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EPIDERMIS
Stratum corneum
Stratum lucidum**
Stratum Basale
Stratum Basale
Lowest epidermal layer, near dermis Good nutrient supply Reproduces by mitosis Cuboidal, columnar in shape Moves to upper epidermis in 27 days Stem cells that produce keratinocytes Melanocytes - # the same for all races
Melanin produced in a melanosome.
Stratum Spinosum
Stratum Spinosum
Living cells Dividing 8-10 cells thick Keratinocytes numerous
Stratus Granulosum
Poor nutrient supply. Flatten layer of cells. 3-5 cells thick. No cell division. Keratin accumulates.
Lucidum
Found only in very thick skin. Translucent. Highly keratinized. Dead cells
Stratum Corneum
25-30 cells thick. Cells are filled with keratin and hardened. Sloughed off. Outer most layer of epidermis. Keratinocytes
Layer
Characteristics
Stratum Basale
Stratum Spinosum
Stratum
Granulosum
Properties Outer layer of skin, composed of 5 zones of stratified epithelium (keratinocytes); contains melanocytes and Langerhans cells.
Function Responsible for the continual replenishing of skin, resists friction, waterproof, prevents water loss.
15-25 layers of dead, flat, keratinized Resists friction, waterproof, prevents squamous epithelial cells, without water loss. nuclei. Normally thin but thick over the soles of the feet and palms of the hands. Only found in thick skin (palms and soles of the feet). Transition between the corneum and lucidum layer. Resists friction, waterproof, prevents water loss.
3-5 layers of keratinocytes containing They form keratin and expel lipids keratin granules. which stick the cells together and form a waterproof barrier. Usually the thickest layer of keratinocyte cells, they are joined together by desmosomal connections. Also contains Langerhans cells. Langerhans cells are part of the immune response.
A layer of cuboidal-shaped cells, lined Keratinocyte cell division occurs here up on a basal membrane. It contains to replenish skin. Melanocytes protect stem cells, keratinocytes, and the skin from UV. melanocytes (pigment cells).
DERMIS
Dermis
Connective tissue layer Collagen and elastic fibers, nerves, blood vessels, muscle fibers, adipose cells, hair follicles and glands. Papillary layer
1/5 of dermis loose areolar connective tissue Highly vascular Dermal papillae - fingerprints
Hypodermis
Attaches the reticular layer to the underlying organs Loose connective tissue and adipose tissue Major blood vessels rete cutaneum
Properties Deep layer of skin, composed of collagen and elastin rich connective tissue. It contains hair follicles, sebaceous glands, blood vessels and sense receptors. Projections push into the epidermis. Highly vascular and innervated. Dense, interlacing connective tissue, predominantly parallel to the skin's surface. Not part of skin layer. Subcutaneous connective tissue, rich in fat and vessels.
Function It is responsible for the elasticity and mechanical support of skin. Supplies the epidermis with nutrients. Important in thermoregulation. Forms finger prints, brings capillaries closer to the avascular epidermis. Forms lines of skin tension, cleavage lines. Protective cushion and insulator.
Papillary
Reticular
Hypodermis
Dermis
Hair Follicle
Hair Follicles
Nails
Plates of highly packed, keratinized cells Protection, scratching, & manipulation Formed by cells in nail bed called the matrix ( in area of lunula) 1 mm / week Eponychium - cuticle
Sebaceous Gland
Exocrine gland Associated with follicle Secretes oily substance Holocrine gland
Sebaceous Gland
Skin Glands
Sebaceous (oil) glands
Usually connected to hair follicles Holocrine glands Fats, cholesterol, proteins, salts, and cell debris Moistens hair and waterproofs skin
Sweat Gland
Exocrine gland Sudoriferous glands Produces water, salts Eccrine glands respond to temperature Apocrine glands respond to pain, emotions
Sweat Gland
Apocrine
Develops scent as bacteria metabolize secretion Stimulated when frightened, during pain, during emotional upset
Eccrine Gland
3. Free Nerve endings detect pain 4. Bulb of Krause (Wilhelm Johann Friedrich Krause) detects cold 5. Corpuscles of Ruffini (Angelo Ruffini) detect heat
Hypodermis (Subcutaneous)
Functions:
1. Regulation of body temperature
Cellular metabolism produces heat as a waste product . High temperature
Dilate surface blood vessels Sweating
Low temperature
Surface vessels constrict shivering
2. Protection physical abrasion dehydration ultraviolet radiation 3. Sensation touch vibration pain temperature
4. Excretion
5. Immunity/ Resistance 6. Blood Reservoir 8-10 % in a resting adult 7. Synthesis of vitamin D uv light aids absorption of calcium
REMINDER
Bring the following materials (by group) on thurs., (Nov. 15, 2012) 1/8 illustration board Glue or paste Scissors Coloring materials (colored pencils, crayons, pastel colors) Craft materials for design
Ceruminous glands
Modified sudoriferous glands Secrete cerumen (ear wax)
Mammary glands
Secrete milk
Skin color
Genetic factors
Same number of melanocytes Albinism
Environmental factors
Uv light or x-rays
Physiological factors
Amount of blood Amount of oxygen
Cyanosis Carotene accumulation Jaundice liver disorder
Wound healing
Inflammation
Blood vessels dilate and become permeable
Heat, redness, swelling and pain
Shallow cuts
Epithelial cells migrate Contact inhibition
Deeper wounds
Inflammatory phase
Fibrin forms clot
Migratory phase
Fibroblasts make granulation tissue
Burns
First degree or partial thickness burn
Only epidermis is damaged Erythema, mild edema, surface layer shed Healing a few days to two weeks No scarring
Rule of Nines
Mucous membranes
Line cavities that open to the exterior Layer of epithelium over connective tissue; epithelium varies with location Tight junctions and goblet cells
Integumentary system is the skin and the organs derived from it (hair, glands, nails) One of the largest organs
2 square meters; 10-11 lbs. Largest sense organ in the body