Vaccinations

 The most recent National Immunization

Coverage Survey of households by Health
Canada, performed in 2002, found that only
56.7% of 2 year old children had received
all of the recommended DPTP/Hib and
MMR immunizations. - Volume Matters: Physician Practice Characteristics
and Immunization Coverage Among Young Children Insured Through a Universal Health Plan
Astrid Guttmann, Doug Manuel, Paul T. Dick, Teresa To, Kelvin Lam, and Therese A. Stukel
Pediatrics 2006; 117: 595-602.
595-602.
 More parents are rejecting
vaccinations for their children

 They consider the vaccines more

dangerous than the disease
 They prefer natural rather than artificial
immunity
 They have a vaccine-injured child (a
growing number)
 They have religious or philosophical
objections to vaccination
Question: Are vaccinated children
healthier than non-vaccinated
children?
 There is no proof vaccinated
children are healthier
No major study has compared
vaccinated and nonvaccinated
children to see which is healthier.
Immunized children: 23.1%
had asthma, 30% had other
allergic illnesses.
Non-immunized children: 0%
had asthma or other allergic
illness.
11% of vaccinated children were
diagnosed with asthma vs 2% of
unvaccinated children - Odent M,
Culpin E, Kimmel T, Pertussis vaccination
and asthma : is there a link ? JAMA 1994 ;
272 : 592-3
 DPPT or MMR and
allergies/asthma
Children vaccinated with
DPPT (or MMR) had 14 times
more asthma and 9.4 times
more eczema than non-
vaccinated children. McKeever TM,
Lewis SA, Smith C. Does vaccination increase the risk of
developing allergic disease?: A birth cohort study. Winter
Abstract supplement to Thorax, 2002; 57: Supplement III
•Measles vaccination in childhood was
related to the following diseases in adult
life: autoimmune diseases…skin
diseases, degenerative diseases of bone
and cartilage and certain tumors. Renne T.
Measles virus infection without rash leads to disease in adult life. Lancet
5 January 1985.
TH1 TH2
 Ingredients
aluminum hydroxide
aluminum phosphate
ammonium sulfate
amphotericin B
animal tissues: pig blood, horse
blood, rabbit brain,
dog kidney, monkey kidney,
chick embryo, chicken egg,
duck egg
calf (bovine) serum
betapropiolactone
fetal bovine serum
formaldehyde
formalin
gelatin
glycerol
human diploid cells (originating
from human aborted fetal
tissue)
hydrolized gelatin
hydrolized gelatin
monosodium glutamate (MSG)
neomycin
neomycin sulfate
phenol red indicator
phenoxyethanol (antifreeze)
potassium diphosphate
potassium monophosphate
polymyxin B
polysorbate 20
polysorbate 80
porcine (pig) pancreatic
hydrolysate of casein
residual MRC5 proteins
sorbitol
sucrose
thimerosal (mercury)
tri(n)butylphosphate,
VERO cells, a continuous line of
monkey kidney cells
washed sheep red blood cells
 Mercury
 One of the most poisonous
substances known to exist in nature.
 Children have received up to 125
times the safe limit of mercury set by
the EPA (autism skyrocketed).
 Symptoms of mercury toxicity
resemble those of autism.
 Mercury is still in use (as of 2003.)
 Question: Do vaccines cause
autism?
• One in 10,000 births were autistic in 1970s
• One in 500 in 1980s
• One in 100 in 1990s
• One in 86 in 2002 (UK study).
• One in 165 today - Pediatrics, July 2006
• In an investigation of unvaccinated Amish population, it was
expected that 200 children would be Autistic (based on the
1/165 ratio) – only 3 were found, and all had been vaccinated!
(Washington Post, April 18th 2005)
• If improved detection/diagnosis were the reason for
increased Autism rates, where are all the Autistic adults?
 Formalin/Aluminum
 Formalin is a dilute formaldehyde solution.
Nearly 50 studies have shown a link
between formaldehyde exposure and
leukemia and brain, colon and lymphatic
cancer.
 Aluminum is a neurotoxin that crosses the
brain/blood barrier. Neustaedter R. The Vaccine Guide,
Berkley, CA: North Atlantic Books. 1996.
 Aluminum
 “After 20 weeks studying the mice, the team found statistically
significant increases in anxiety (38 percent); memory deficits
(41 times the errors as in the sample group); and an allergic
skin reaction (20 percent). Tissue samples after the mice were
"sacrificed" showed neurological cells were dying. Inside the
mice's brains, in a part that controls movement, 35 percent of
the cells were destroying themselves” – Study performed at
UBC, 2006
 Research by Dr. Hugh Fudenberg, M.D., the world's leading
immunogeneticist and 13th most quoted biologist of our times
(author of nearly 850 papers in peer reviewed journals),
shows that individuals who had five consecutive flu shots
have a ten times higher chance (1000%) of getting
Alzheimer's disease than if they had only one or two or no
shots.
 2 questions
Are vaccines effective at preventing
disease?
Are vaccines responsible for eradicating
infectious diseases in 20th century?
 Question: are vaccinations
“effective?”
What does effective mean?
CDC: “Effective” means antibodies
are produced, not clinical
effectiveness (i.e. no disease).
However, there is often no correlation
between antibodies and resistance to
disease.
“[Pertussis] infections are common in
an immunized population…more
prevalent than previously documented.”
98% were vaccinated in this population.
He Q, Vijanen MK, Arvilommi H et al. Whooping cough caused by Bordetella
pertussi and Bordetella parapertussis in an immunized population. Journal of
the American Medical Association. 1998;280:635-637.
Outbreaks have occurred in
100% vaccinated populations.
Morbidity and Mortality Weekly Report. US Govt. 12/29/89/38(S-
9):1-18.

“80% cases of measles are

contracted in vaccinated
people.” Morbidity and Mortality Weekly Report. US Govt.
6/6/86/35(22):366-70.
 More pertussis since vaccination

With mandatory vaccination and 5 doses of

DPT vaccine, pertussis occurs at a far
higher rate now than before the
introduction of the vaccine. “There is
substantial underreporting of pertussis…
including hospitalizations.” Sutter RW and Cochi SL.
Pertussis hospitalizations and mortality in the United States, 1985-
1988. JAMA. 1992;267(3):386-390.
 Whooping cough deaths increase
despite all the vaccinations
“The number of infants dying from whooping
cough is rising despite record high
vaccination levels. All the deaths in 2000
occurred among infants under the age of 4
months.”
“Since the early 1980s, reported pertussis
incidence has increased cyclically with
peaks occurring every 3-4 years.”
Morbidity and Mortality Weekly Report. Feb 1, 2002;51:73-76.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5104a1.htm
 Vaccines interfere with
transplacental immunity
Girls who are vaccinated have
less protection to pass on to
their unborn child. (a) More
measles now occurs in
children less than 1 and adults
25+ (b) (a) Papania M, Baughman AL, Lee S, et al Increased
susceptibility to measles in infants in the United States. Pediatrics.
1999;104(5):e59 National Immunization Program, Epidemiology
Program Office, Centers for Disease Control and Prevention,
Atlanta, Georgia 30333, USA. (b) MMWR 1991;40:369-372 in
JAMA;1991;265(24).
 Hib vaccine
Since the vaccine Hib meningitis has
declined but other types of meningitis
have increased to levels higher than
before the Hib vaccine was used.
 Replacement chapter for “immunization against infectious disease”
1996: Chapter 23, Meningococcal. [British] Dept of Health. [Pub by
NHS Executive.)
www./doh.gov.uk/meningitis-vaccine/chapter23.htm
 Beattie G. Vaccination: A Parent’s Dilemma. Australia: Bunya
Books. 1997.
 Mumps Outbreak in Atlantic
Canada
 “The Halifax outbreaks have occurred in
both a doubly vaccinated cohort of
adolescents, and a singly vaccinated
cohort of young adults. The nature of these
outbreaks raises questions as to he t

efficacy of the MMR vaccine in each of

these cohorts.” - Two successive outbreaks of mumps in Nova Scotia
among vaccinated adolescents and young adults Gaynor Watson-Creed, Andrea Saunders,
Jeffrey Scott, Luis Lowe, Janice Pettipas, and Todd F. Hatchette

Can. Med. Assoc. J. 2006; 175: 483-488.

 Tetanus
 Associated with improper wound cleaning,
malnutrition and a weak immune system.
 Decreased 92% from mid-1850s to early
1900s (before vaccination).1900 -1999:
473 - 70 deaths. Most occur in those over
50 (95% of fatalities); 5% of tetanus
occurs under age 20. Fatalities are rare
among younger people.
 Chicken pox (varicella)
A mild self-limiting disease that gives
permanent life long immunity if caught
as a child but is much more
dangerous in adults.
The chances of a child becoming
seriously ill and dying from chicken
pox are about equal to winning the
lottery.
 NNT
 For varicella vaccination, we estimated that 34 000 people
would need to be vaccinated to prevent 1 death (using mortality
rates reported by Brisson and Edmunds25 and assuming 100%
efficacy against the varicella-zoster virus and no waning in
protection). To prevent 1 meningococcal-related death, we
estimated that about 21 000 people would need to be
vaccinated (using mortality data reported by De Wals and
associates26 and assuming 100% efficacy against types A, C, Y
and W135). - Estimating the number needed to vaccinate to prevent
diseases and death related to human papillomavirus infection Marc Brisson, PhD,
Nicolas Van de Velde, MSc, Philippe De Wals, MD PhD, and Marie-Claude Boily, PhD
Can. Med. Assoc. J. 2007; 177: 464-468
 Question: Did vaccines eliminate
diseases?
“Nearly 90% of the total decline in
mortality (scarlet fever, diphtheria,
whooping cough, and measles)
between 1860 and 1965 occurred
before the introduction of
antibiotics and widespread
immunization.” Illich, I. Medical Nemesis. Chapter 1-The
Epidemics of Modern Medicine, NY: Bantam Books 1976
 Scarlet fever, typhoid fever and
pertussis
Scarlet fever, typhoid fever and
pertussis were major killers.
No vaccine was introduced for scarlet
fever and typhoid fever.
All three diseases declined to virtually
zero.
 Polio vs Aseptic Meningitis
 "Prior to 1954 any physician who reported paralytic poliomyelitis was doing his patient a
service by way of subsidizing the cost of hospitalization and was being community-
minded in reporting a communicable disease. The criterion of diagnosis at that time in
most health departments followed the World Health Organization definition: "Spinal
paralytic poliomyelitis: signs and symptoms of nonparalytic poliomyelitis with the
addition of partial or complete paralysis of one or more muscle groups, detected on two
examinations at least 24 hours apart."
 - Dr. Bernard Greenberg, Chairman of the Committee on Evaluation and Standards of
the American Public Health Association

 In 1955 the criteria were changed to conform more closely to the definition used in the
1954 field trials: residual paralysis was determined 10 to 20 days after onset of illness
and again 50 to 70 days after onset
 Example: In one US county in July 1955 there were 273 cases of polio reported for 50
cases of asceptic meningitis, compared to 5 cases of polio in 1966 and 256 cases of
aseptic meningitis.
 In Canada, the Dominion Bureau of Statistics
issued an official bulletin in June 1959 titled
Poliomyelitis Trends, 1958. "Data shown in this
report are confined to paralytic poliomyelitis only.
It may be noted that the Dominion Council of
Health at its 74th meeting in October 1958
recommended that for the purposes of national
reporting and statistics the term non-paralytic
poliomyelitis be replaced by 'meningitis, viral or
aseptic,' with the specific viruses shown where
known."
Flu Shot Video
THE PROBLEM?
 THE PROBLEM
 Only 3 of the 10000+ strains are added
each year
 They are selected nine months in advance
(to allow manufacturers time)
 The three strains are based on which ones
are circulating in south east Asia at the
time
 There is NO GUARANTEE that those will
be the strains circulating this “flu season”
 HOW EFFECTIVE?
 Last year, the strains were a non-match
 For the first time ever, all three strains
have been changed this year
 In the best years, the shot has been 0%-
14% effective
 Efficacy is measured by antibody response
vs avoidance of disease
 Most people will show antibody response
to influenza by the end of the season
 “POLICY vs EVIDENCE”
 BMJ Oct 26, 2006 - Summary points:
 Public policy worldwide recommends the use of inactivated
influenza vaccines to prevent seasonal outbreaks
 Because viral circulation and antigenic match vary each
year and non-randomised studies predominate, systematic
reviews of large datasets from several decades provide the
best information on vaccine performance
 Evidence from systematic reviews shows that inactivated
vaccines have little or no effect on the effects measured
 Most studies are of poor methodological quality and the
impact of confounders is high
 Little comparative evidence exists on the safety of these
vaccines
 Reasons for the current gap between policy and evidence
are unclear, but given the huge resources involved, a re-
 Archives of Pediatric and Adolescent Medicine, Oct
2008: “significant influenza vaccine effectiveness could
not be demonstrated for any season, age, or setting”
 American Journal of Respiratory and Critical Care
Medicine, Sept 2008: “no decrease in deaths from
influenza and pneumonia despite the fact that
vaccination rates have risen from 15% in 1980 to 65%
now”
 National Institute of Allergy and Infectious Disease: “We
conclude that frailty selection bias and use of non-
specific endpoints such as all-cause mortality have led
cohort studies to greatly exaggerate vaccine benefits”
 Cochrane Database of Systemic Reviews, 2006: A
review of 51 studies involving 260000 children found no
evidence that the flu vaccine is any more effective than
a placebo
 SWINE FLU
Symptoms are similar to seasonal flu, but
milder
All deaths have had underlying health
problems
In 1976, the Swine Flu vaccine killed more
people than the Swine Flu itself
Next fall expect recommendations for all
people to be vaccinated
 GARDASIL
Gardasil has been marketed as a vaccine
against cervical cancer
In fact, it is a vaccine for HPV – the virus
that causes genital warts
In certain cases, genital warts can become
cancerous
Problem: Only two strains of 200+ are in the
shot!
 GARDASIL
Problem: It was only studies in 1200 girls, of which
only 100 were 9 years old
Problem: Long tem side effects as well as
effectiveness of vaccine have never been
studies
Problem: Less than 400 Canadian women die from
cervical cancer annually
Problem: there have been tens of thousands of
adverse reactions, including 30+ deaths
attributed to the vaccine
 GARDASIL
PROBLEM: IS IT EVER REALLY A GOOD
IDEA TO INJECT NINE YEAR OLD
GIRLS WITH THE VIRUS THAT CAUSES
GENITAL WARTS?
 HOW DANGEROUS ARE
VACCINES?

Exactly how many children are injured by

vaccines?
 Doctors rarely report damage
“Doctors
underreport
adverse vaccine
reactions by
90%.” US Food and
Drug Administration
"Investigative Report on the
Vaccine Adverse Event Reporting
System.“ NVIC.
“The company estimates
about a 50-fold underreporting
of adverse events in the
passive reporting system.”
Froeschle, J. Connaught Laboratories. Adverse events associated with
childhood vaccines, evidence bearing on causality. Washington DC:
Institute of Medicine presentations. 5/11/92; 328 Appendix. B.
 One in 500 injuries reported…
 An analysis of the CDC’s own data
demonstrates that the number of actual
injuries from the rotavirus vaccine is 500
times the injuries reported to VAERS.
 http://search.cdc.gov/search97cgi/s97is.dll?queryText=
Kaiser+Permanente+and+rotashield&SortField
=score&Action=FilterSearch&Collection
=CDCALL1&ResultTemplate=nsearchresult.hts&filter=
newsearch.hts
 http://www.cdc.gov/nip/ACIP/minutes/acip-min-oct01.rtf
Vaccine(s) Filed Compensated Dismissed
Injury Death Total
DT (diphtheria-tetanus) 62 9 71 20 48
DTP 3,281 695 3,976 1,263 2,674
DTP-HIB 16 8 24 3 19
DtaP 250 66 316 81 102
DTaP-Hep B-IPV 25 10 35 4 4
DTaP-HIB 6 1 7 3 0
Td (tetanus-diphtheria) 128 2 130 51 53
Tdap 4 0 4 0 0
Tetanus 59 2 61 21 30
Hepatitis A (Hep A) 11 0 11 1 3
Hepatitis B (Hep B) 526 45 571 123 255
Hep A- Hep B 4 0 4 3 1
Hep B-HIB 3 0 3 2 1
HIB 17 3 20 6 5
HPV (human papillomarvirus) 4 0 4 0 0
Influenza (Trivalent) 214 13 227 57 24
IPV (Inactivated Polio) 260 14 274 7 264
OPV (Oral Polio) 279 27 306 157 146
Measles 142 19 161 54 107
Meningococcal 4 0 4 0 0
MMR (measles-mumps-rubella) 762 52 814 282 328
MMR-Varicella 6 0 6 1 0
MR 15 0 15 6 9
Mumps 10 0 10 1 9
Pertussis 5 3 8 2 6
Pneumococcal Conjugate 23 3 26 5 13
Rotavirus 31 1 32 20 11
Rubella 189 4 193 70 123
Varicella 40 2 42 21 13

TOTAL 11,757 994 12,746 2,266 4,755