1.

Alcohol consumer

2 Often use barbiturate at the same time with alcohol

3. Using drug which make slender of type of amphetamine and metamphetamine by injection

Amphetamine Barbiturate ( Dormicum ) OMZ ( omeprazol)

Neurobium
Diazepam Propovol

o In stomach : liquid shabu o At kidney and bile : morphine

o At urine : and amfetamin of metamfetamin high rate

o At body was found propovol and benzodentin that was represented the root cause death

Activity of this medicine is quick that is in 30 minute and stay until 5-7 hours. Midazolam was bound plasma protein counted 96%.Reorganizing allows quickly and perfection ( 60-80%) becoming final metabolite 1-hydroksimethyil-midazolam which is released to pass urin in the form of glukuronida. plasma of T 1 / 2 - its very short that is 1,5-2,5 [hours of metabolit finally 60-80 minute

Barbiturate : 7,5-15 mg ( maleat) local Anaesthesia Pramedication : oral 25 minute mg45 ; 1ntramuskular 5 mg ( chloride) Side Effects : if exceeding dose above can cause resistance in respiration of which can become fatally

Blocking of acid exretion do not depended from plasma rate, but from surface under curve ( AUC). Its Reabsorption is complete, for 2-5 hours. It has high Protein plasma ( 95%), t1/2 plasma its only more or less 1 hour but its activity stay 24 hour. At heart, this substance is reorganized entirely become inactive metabolites, which is excreted by urine to 80%. Between blood and its effect do not have correlation.

Omeprazol ravelled in acid atmosphere so that require to be given by acid proof cladding. Side effects : head pain, muscle pain, sleepless, Eliminasi of and diazepam of fenitoi pursued

Blocking of acid exretion do not depended from plasma rate, but from surface under curve ( AUC). Its Reabsorption is complete, for 2-5 hours. It has high Protein plasma ( 95%), t1/2 plasma its only more or less 1 hour but its activity stay 24 hour. At heart, this substance is reorganized entirely become inactive metabolites, which is excreted by urine to 80%. Between blood and its effect do not have correlation.

ANALYSIS CASE
Consumption barbiturate which have long time with at the same time alcohol will improve barbiturate activity which caused poisoned Usage of alcohol in a state of empty stomach can improve acid of gastric and to decrease it, was given omeprazol. This drug can degrade acid quickly and strongly by resistance pump proton.

Usage of drug which made slender contains amfetamin and metamfetamin will stimulate CNS, increase heart frequency and blood pressure. represent symptom of hipoksia. To overcome recuring Usage of this amfetamin caused tolerance

because condition of overdosis, arise painful and spasm then is given neurobion, but it is not effective.

Giving high dose of diazepam ( 400 iv mg). It can more serious condition of hipoksia and cause to desist breath at once