PHARMACEUTICAL PACKAGING BY METALS

PRESENTED BY : SHAGUFTA KHAN B. PHARM VIII SEMESTER

PHARMACEUTICAL PACKAGING
Pharmaceutical packaging is the means of providing protection,

presentation, identification and information, containment, convenience to encourage compliance with and closures.
FDA-

and

Packaging is the science, art and technology of enclosing or protecting products for distribution, storage, sale, and use.
An economical means of providing protection, presentation,

identification, information and convenience for pharmaceuticals product from the moment of production until it is used or administered.

METALS
Metals used in packaging including Tin (15%) Aluminum (60%) Lead (25%)

These metals are useful in the preparation of collapsible tubes.

Type of metal containers

a. Collapsible tubes b. Metal containers for tablets and capsules c. Metal foil

TIN
Tin:
F00D PHARMACEUTICA LS product for which purity is an important consideration

ADVANTAGES
Tin is chemically inert of all collapsible tube metals. It offers a good appearance and compatibility with a wide

range of products.

Aluminum

Aluminum tubes offer significant savings in

product shipping costs because of their light weight. They provide good appearance

Lead
Lead has the lowest cost of all tube metals and is

widely used for nonfood products such as adhesives, inks, paints, and lubricants.
Lead should never be used alone for anything

taken internally because of the risk of lead poisoning.

The inner surface of the lead tubes are coated

and are used for products like fluoride toothpaste.

Type of metal containers:

Collapsible tubes Metal containers for tablets and capsules Metal foil

COLLAPSIBLE TUBES
The collapsible metal tube is an attractive

container that permits controlled amounts to be dispensed easily, with good re closure and adequate environmental protection to the product. The risk of contamination of the portion remaining in the tube is minimal, because the tube does not "suck back. It is light in weight and unbreakable, and it lends itself to high-speed automatic filling operations. The ductile metals used for collapsible tubes are tin (15%), aluminum (60%), and lead (25%)

COLLAPSIBLE TUBES
Collapsible Tubes

Plastic Collapsible Tubes

Laminated tubes Metal Collapsible Tubes

METAL COLLAPSIBLE TUBES

Advantages Permits controlled amount to be dispensed easily with good reclosuer & provides adequate protection to the product.

Does not suck back

Disadvantages Corrosion & Breakage

METAL FOILS
Thin sheets of metals. <100 m thickness. Aluminium barrier Attractive Reflective surface Thick alluminium sheets tray for blister pack. Thin alluminium foil vaccum depositioning.

Metal foils

Containers for tablet and capsules

Closures Emphasised On Metals

Closures-

METALS 1.Tin 2. Aluminium

Closures Are Available In 5 Basic Designs 1) Screw-on Closure 2) Crimp-on Closure 3) Roll-on Closure 4) Friction Closure 5) Press-on Closure

SCREW CAP CLOSURES

ROLL ON

Tamper Resistant Packaging

As per FDA It is a packaging in which there is an indication or barrier to entry which if breached or missing, can reasonably be expected to provide visible evidence to consumer that tampering has occurred.

Tamper Resistant Packaging

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Film wrappers Blister package Strip package Bubble pack Shrink seal & bands Aerosol containers Bottle seals Tape seals Breakable caps Foil, paper or plastic pouch

FILM WRAPPERS

BLISTER PACKAGING

STRIP PACKING

AEROSOL CONTAINERS

Advantage of Metals
They are sturdy.

They are impermeable to light, moisture,and

gas. They are light in weight as compared to glass containers. Labels can be printed directly on to their surface.

Disadvantage of metals
They are expensive.

They may shed metal particles into

pharmaceutical products. They are not generally used for extemporaneous dispensing. They react with certain chemicals of drug.

THANK YOU.