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Jeng-Yee Lin MD PhD Division of Plastic Surgery, Taipei Medical University Hospital nad Taipei Medical University
Wound Healing
Wound healing process: Hemostasis phase Inflammatory phase Proliferation phase Scar Remodeling
Hemostasis (0-3hr)
Vasoconstriction Platelet aggregation PDGF Coagulation cascade reaction
Biological wound dressing: Autograft skin: STSG FTSG; xenograft skin Synthetic wound dressing
Wound dressing
VAC-negative pressure dressing: promote cell cycle and granulation tissue growth. continue draining of exudate of the wound. avoid its use in malignancy.
Wound dressing
Foam: polyurathane film or porous sponge. Hydrogel: water 70-90%, alternative to wet dressing. Hyrocolloid: Duoderm, Comfeel,Alleyvn, slowly absorbing water. Calcium alginate: promote hemostasis Collagen-base bilayer skin substitute: Biobrane, Integra Silver containing dressing: Ag coated high densisty
Fluid resuscitation
1.Crystalloid but not colloid fluid resuscitation in the first 24 hr. 2.Colloid fluid can be infused 24 hr after burn injury. 3.Volume of resuscitation can be more than Parkland formula if inhalation injury is suspected. 4. General guideline: keep 30-50ml/hr urine output after acute stage.
advanced medical disease (DM) > 10% major burn injury >20% burn injury involving joints or perineum
Facial trauma
Facial bone fracture Facial lacerations
Facial laceration
Watch out for lacrimal duct, facial nerve, or salivary gland injury
Image study
X-ray Waters view: Zygoma /arch view: Nasal bone: most common facial fx CT scan: more sensitive and specific than CT
Compartment syndrome
Etiology : Trauma/bone fracture Crush injury Burn injury Vascular injury Tight cast Drug overdose
Tx of compartment syndrome
Early and prompt fasciotomy prevent further tissue and nerve injury. Fasciotomy is urgently done based on clinical finding not measurement of an absolute value in tissue pressure
Diabetic foot
Etiological risk: 1.Peripheral neuropathy 2 Peripheral vascular disease
Decubitus ulcer
Ischemic tissue due to pressure on tissue greater than the arteriole oncotic pressure. Presure time relationship Grade I-IV
Risk factors
Moisture Friction: Shear force: avoid > 30 degree head up in supine position
Decubitus ulcer
Tx Osteotomy of bony prominence Debridement VAC negative pressure wound closure.
S/S: 5P: pain, paresthesia, pallor, pulselessness, poikilothermia hairless & scaly skin, intermittent claudication Ankle-brachial index (ABI) <1
PAOD
Venous ulcer
Venous congestion results in hypoxia of local tissue Perivascular thick fibrin also impede oxygen diffusion Leukocyte migrate more slowly than usual and become activated, damaging the vascualr endothelium. Macromolecule/hemosiderin leaking into the
Tx of venous ulcer
Keep wound moist and clean Compression and debridement Skin graft or bilayer skin substitute. Hyperbaric oxygen therapy may help stasis dermititis healing.
Diabetic ulcer
Neuropathic impairment of musculoskeletal balance Decrease immune system from leukocyte dysfunction and peripheral vascular disease Tx : Keep wound clean and moist, attentive debridement and use of PDGF and TGF-beta growth factor topical agent may improve wound