In this episode, the J. Craig Venter Institute's senior computational biologist Douglas Rusch talks about the Global Ocean Sampling Expedition's genomic treasure hunt and the first batch of research results that just came out. We'll also talk about an analysis of pharmaceutical agents in the Journal of Natural Products that showed that the majority of approved agents in the last quarter century are still derived from natural products. Plus we'll test your knowledge about some recent science in the news. Websites mentioned include http://www.plos.org; http://collections.plos.org/plosbiology/gos-2007.php; http://pubs.acs.org/journals/jnprdf