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Disclaimer: The following information is not a substitute for medical care or medical counseling and is not intended for the diagnosis, treatment or prevention of disease or symptoms. The following statements made regarding nutritional supplements have not been evaluated by the FDA.
Supplements that replace drug induced nutrient depletions and minimize side effects (vitamin C, CoQ10, folic acid, zinc, B vitamins.) Supplements that may minimize dependence on OTC/non prescription medications (antacids, NSAIDs, etc.)
Epocrates.com
Easy reference for serious and common side effects as well as multiple drug interactions Download free basic app for smart phones or free basic program for computer.
Free Statins With Fast Food Could Neutralize Heart Risk, Scientists Say Science Daily (August 12, 2010) Fast food outlets could provide statin drugs free of charge so that customers can neutralize the heart disease dangers of fatty food, researchers at Imperial College London suggest in a new study.
Lipitor
Serious Reactions
Myopathy Tendon Rupture Rhabdomyalisis Renal Failure Hepatotoxicity Pancreatitis Anaphylaxis Angiodema Lupus Polymalgia Rheumatica Dermatomyositis Vasculitis Thrombocytopenia Leukopenia Hemolytic Anemia Photosensitivity Stevens Johnson Syndrome
Lipitor
Common Reactions
Headache Infection Rhinitis Sinusitis Myalgia Diarrhea Arthritis Rash Abdominal pain Back Pain Flu syndrome Allergic reaction Dyspepsia Flatulence Pharyngitis Constipation Elevated CK Elevated liver enzymes Decreased CoQ10
For more complete discussion on cholesterol, watch November 2011 webinar on lab testing
Antacid Medications
In 2009, Nexium was the second best selling prescription drug with a 4.6 sales increase from 2008 - drugs.com Prevacid was the tenth best selling prescription drug drugs.com How many over the counter antacid medications are sold each year?
Hypochlorhydric stomach: a risk condition for calcium malabsorption and osteoporosis? Scandinavian Journal of Gastroenterology. 2010;45(2):133-8. Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Gastroenterolgy 2010 Jul;139(1):93-101.
Warfarin
Serious Reactions hemorrhage skin/tissue necrosis gangrene cholesterol embolism purple toes syndrome hypersensitivity rxn anaphylactic rxns cholestatic jaundice hepatitis vasculitis tracheobronchial calcification anemia
Warfarin
Common Reactions
bleeding bruising easily abdominal cramps/pain nausea/vomiting diarrhea flatulence/bloating fatigue/malaise lethargy asthenia headache dizziness pruritus edema dermatitis rash/urticaria fever cold intolerance paresthesias alopecia
Plavix
Serious Reactions
bleeding, severe, fatal hemorrhage TTP neutropenia anaphylactoid rxns serum sickness angioedema hypersensitivity rxn Stevens-Johnson syndrome toxic epidermal necrolysis hepatitis hepatic failure, acute pancreatitis
Plavix
Common Reactions nausea dyspepsia diarrhea abdominal pain hemorrhage purpura rash pruritus influenza-like sx cough bronchitis dizziness headache fatigue arthralgia chest pain palpitations epistaxis UTI
Aspirin side effects kill about a thousand people a year in the US. If aspirin were a new drug, it would have a tough time getting approved by the FDA and would only be available by prescription. Taking any dose of aspirin on a regular basis can triple your risk of dangerous gastrointestinal bleeding, according to some studies
Continued: Additional research indicates that if you're consuming just one serving of alcohol every day while taking aspirin on a regular basis, the risk of bleeding increases by another 250 percent. In other words, if you are one of the millions of Americans who have a glass of wine each day in the hope of improving your health, but are also taking aspirin, your risk of internal bleeding becomes seven times greater than if you didn't drink or take aspirin
Continued:
Aspirin also interferes with absorption of vitamin C, and regular use of aspirin can deplete your gastrointestinal lining of vitamin C. Taking equal doses of vitamin C and aspirin decreases the amount of stomach damage that occurs when compared to taking aspirin alone, according to research done at a German university. The protective effect of vitamin C on aspirin side effects has been demonstrated in healthy people and people with inflammation of the stomach caused by infection with Helicobacter pylori, a bacterium that causes ulcers.
Novel use of silymarin as delayed therapy for acetaminophen-induced acute hepatic injury.
Forsch Komplementmed 2010;17(4):209-13 Abstract AIM: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyllanthus urinaria extract when used to rescue mice from acetaminophen-induced acute liver injury. In the present study, we further compared the therapeutic action of silymarin with N-acetyl cysteine (commonly used in clinical practice for emergency treatments) as a rescuer in mice after administering a lethal dose of acetaminophen for 24 h.
METHODS: Acute liver injury was induced in the treatment groups by intraperitoneally administered acetaminophen at a dose of 550 mg/kg body weight on day 1. The control group received an equal volume of physiological saline intraperitoneally. From day 2 to 4, the treatment groups received various doses of silymarin or N-acetyl cysteine orally once daily, while the control group and the acetaminophen group received an equal volume of water orally. The mortality rate was recorded in all groups. RESULTS: Silymarin greatly improved the counteracting effects on mortality rate as compared to N-acetyl cysteine. CONCLUSION: Silymarin should be further considered as an antidote for patients with acetaminophen induced acute hepatic injury and delayed treatment.
Statins (Cardio Plus, Livaplex, Tuna Oil) Antacids (Zypan) Anti platelets, anti coagulants (Cyruta Plus) Acetaminophen/Tylenol (Silymarin) NSAIDs (Cholorophyll Complex, Tuna Omega 3 Oil)
When in Doubt
Catalyn (6 per day)
Whole food sources of all known vitamins