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  • MES &amp Process Minds 2012 - Agenda

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    we.CONECT Global Leaders GmbH
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    Improving Quality & Compliance and increasing Operational Excellence with Manufacturing Execution Systems in Pharma & Life Sciences Industries Life sciences producers are faced with a multitude of new challenges. Economic pressures like globalisation, litigation and government mandated pricing threaten operating margins, while an ever-changing regulatory environment makes it harder to stay compliant. New scientific bases for innovative products increase the complexity of manufacturing. Initiatives, such as targeted treatments and medicine tailored to specific subsets of patients, challenge the industry to change their supply strategy from a classic push-oriented model, to a pull-oriented model, already common in other industries. In a regulated environment such as the pharmaceutical & Life Science Industry, it is imperative that manufacturing shop floor information is visible in the boardroom on a real time, or near real time basis to enable informed decision-making throughout the supply chain. In addition, MES projects for international markets require new processes for batch records, validation and reporting. The pharma & life sciences industry was the driving force behind many of the concepts of MES, including genealogy, electronic signatures, quality control, specifications, batch execution, paperless batch etc. Of particular importance for this industry is to ensure process quality, efficiency and safety. Process understanding will be the key to manage these challenges and to build an efficient pharmaceutical production. Manufacturers will have to turn to fully integrated IT solutions to achieve operational excellence. In this regard Manufacturing IT such as Manufacturing Execution Systems is one of the key business enablers for reaching Operational Excellence. An MES controls, optimizes, and documents business processes executed on the shop floor in full compliance with all the pharmaceutical requirements. It is the goal of an MES to increase security and reliability of the manufacturing process and to improve product quality. Cost effectiveness is another important element, mainly for gaining approval for MES projects. In order to develop an ROI program for an MES, project leaders and stakeholders must be able to identify the long-term goals of their manufacturing execution process and often justify projects with hard cost savings. Here, the question is where the major cost drivers for MES projects are and which strategy is the right one to reduce costs. On the other hand MES has a high potential for new plant construction, particularly when the production has a high degree of automation and material flow. MES reduces the expenses for the documentation of production data, Batch losses due to event management and functions of the MES systems are dramatically reduced. The functions of MES go far beyond the horizontal and vertical integration, MES is positioned as an independent system of its functions, in various models such as the NAMUR S-88, ISA, FDA or the MESA-c-MES model, MES has already been integrated. The Web technology opens the way for Web-based Systems to be networked in production. The companies are global “on-time-and on-location” which means they can get real-time date at their mobile terminals. In addition, an efficient and integrated MES provides full visibility, real-time monitoring of production lines according to the different roles, tasks and permissions in production management of the pharma & life sciences industry. It is now time to expand the level of integration and automation further to a more flexible manner to respond to changing market demands. With international Top-Speakers at a senior executive level, the MES & Process Minds 2012 will establish a new approach in finding the right MES excellence strategy for pharma and life sciences industries. We look forward to welcoming you! Your we.CONECT team

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    Improving Quality & Compliance and increasing Operational Excellence with Manufacturing Execution Systems in Pharma & Life Sciences Industries Life sciences producers are faced with a multitude of new challenges. Economic pressures like globalisation, litigation and government mandated pricing threaten operating margins, while an ever-changing regulatory environment makes it harder to stay compliant. New scientific bases for innovative products increase the complexity of manufacturing. Initiatives, such as targeted treatments and medicine tailored to specific subsets of patients, challenge the industry to change their supply strategy from a classic push-oriented model, to a pull-oriented model, already common in other industries. In a regulated environment such as the pharmaceutical & Life Science Industry, it is imperative that manufacturing shop floor information is visible in the boardroom on a real time, or near real time basis to enable informed decision-making throughout the supply chain. In addition, MES projects for international markets require new processes for batch records, validation and reporting. The pharma & life sciences industry was the driving force behind many of the concepts of MES, including genealogy, electronic signatures, quality control, specifications, batch execution, paperless batch etc. Of particular importance for this industry is to ensure process quality, efficiency and safety. Process understanding will be the key to manage these challenges and to build an efficient pharmaceutical production. Manufacturers will have to turn to fully integrated IT solutions to achieve operational excellence. In this regard Manufacturing IT such as Manufacturing Execution Systems is one of the key business enablers for reaching Operational Excellence. An MES controls, optimizes, and documents business processes executed on the shop floor in full compliance with all the pharmaceutical requirements. It is the goal of an MES to increase security and reliability of the manufacturing process and to improve product quality. Cost effectiveness is another important element, mainly for gaining approval for MES projects. In order to develop an ROI program for an MES, project leaders and stakeholders must be able to identify the long-term goals of their manufacturing execution process and often justify projects with hard cost savings. Here, the question is where the major cost drivers for MES projects are and which strategy is the right one to reduce costs. On the other hand MES has a high potential for new plant construction, particularly when the production has a high degree of automation and material flow. MES reduces the expenses for the documentation of production data, Batch losses due to event management and functions of the MES systems are dramatically reduced. The functions of MES go far beyond the horizontal and vertical integration, MES is positioned as an independent system of its functions, in various models such as the NAMUR S-88, ISA, FDA or the MESA-c-MES model, MES has already been integrated. The Web technology opens the way for Web-based Systems to be networked in production. The companies are global “on-time-and on-location” which means they can get real-time date at their mobile terminals. In addition, an efficient and integrated MES provides full visibility, real-time monitoring of production lines according to the different roles, tasks and permissions in production management of the pharma & life sciences industry. It is now time to expand the level of integration and automation further to a more flexible manner to respond to changing market demands. With international Top-Speakers at a senior executive level, the MES & Process Minds 2012 will establish a new approach in finding the right MES excellence strategy for pharma and life sciences industries. We look forward to welcoming you! Your we.CONECT team

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    87 visualizzazioni8 pagine

    MES &amp Process Minds 2012 - Agenda

    Caricato da

    we.CONECT Global Leaders GmbH
    Improving Quality & Compliance and increasing Operational Excellence with Manufacturing Execution Systems in Pharma & Life Sciences Industries Life sciences producers are faced with a multitude of new challenges. Economic pressures like globalisation, litigation and government mandated pricing threaten operating margins, while an ever-changing regulatory environment makes it harder to stay compliant. New scientific bases for innovative products increase the complexity of manufacturing. Initiatives, such as targeted treatments and medicine tailored to specific subsets of patients, challenge the industry to change their supply strategy from a classic push-oriented model, to a pull-oriented model, already common in other industries. In a regulated environment such as the pharmaceutical & Life Science Industry, it is imperative that manufacturing shop floor information is visible in the boardroom on a real time, or near real time basis to enable informed decision-making throughout the supply chain. In addition, MES projects for international markets require new processes for batch records, validation and reporting. The pharma & life sciences industry was the driving force behind many of the concepts of MES, including genealogy, electronic signatures, quality control, specifications, batch execution, paperless batch etc. Of particular importance for this industry is to ensure process quality, efficiency and safety. Process understanding will be the key to manage these challenges and to build an efficient pharmaceutical production. Manufacturers will have to turn to fully integrated IT solutions to achieve operational excellence. In this regard Manufacturing IT such as Manufacturing Execution Systems is one of the key business enablers for reaching Operational Excellence. An MES controls, optimizes, and documents business processes executed on the shop floor in full compliance with all the pharmaceutical requirements. It is the goal of an MES to increase security and reliability of the manufacturing process and to improve product quality. Cost effectiveness is another important element, mainly for gaining approval for MES projects. In order to develop an ROI program for an MES, project leaders and stakeholders must be able to identify the long-term goals of their manufacturing execution process and often justify projects with hard cost savings. Here, the question is where the major cost drivers for MES projects are and which strategy is the right one to reduce costs. On the other hand MES has a high potential for new plant construction, particularly when the production has a high degree of automation and material flow. MES reduces the expenses for the documentation of production data, Batch losses due to event management and functions of the MES systems are dramatically reduced. The functions of MES go far beyond the horizontal and vertical integration, MES is positioned as an independent system of its functions, in various models such as the NAMUR S-88, ISA, FDA or the MESA-c-MES model, MES has already been integrated. The Web technology opens the way for Web-based Systems to be networked in production. The companies are global “on-time-and on-location” which means they can get real-time date at their mobile terminals. In addition, an efficient and integrated MES provides full visibility, real-time monitoring of production lines according to the different roles, tasks and permissions in production management of the pharma & life sciences industry. It is now time to expand the level of integration and automation further to a more flexible manner to respond to changing market demands. With international Top-Speakers at a senior executive level, the MES & Process Minds 2012 will establish a new approach in finding the right MES excellence strategy for pharma and life sciences industries. We look forward to welcoming you! Your we.CONECT team

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    ImprovIng QualIty & ComplIanCe and InCreasIng operatIonal exCellenCe wIth manufaCturIng exeCutIon systems In pharma & lIfe

    sCIenCes IndustrIes
    24th 25th september 2012 | novotel BerlIn am tIergarten more than 15 Case studIes | ICeBreaker sessIon | world Caf sessIon | Challenge your peers http://pharma-mes.we-conect.com

    researChed & developed By

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    oVerView
    SPEAKERS

    mes & process minds 2012 MAIN TOPICS


    > strategies and criteria for the selection of mes, technical and organisational requirements for mes and selection of appropriate systems > distributed systems from the perspective of global harmonisation > Compliant documentation, regulatory guidance and Quality assurance for manufacturing excellence / mes as the bridge to achieve pat and Qbd > automation infrastructure for operational excellence: remote operations management, automation services strategy & in-plant mobility solutions > mes Infrastructure for Cloud Computing within a regulated Industry / gmp environment > systemised control of production & manufacturing intelligence: Integrated It systems and mes management in process industries operations > next generation It and process control solutions: Closing the gap between r&d and manufacturing through intelligent mes > review the value of early employee engagement and training for mes > Cost management and effectiveness analysis for mes projects > serialisation requirements for mes > Integration of mes & mobile devices and the use of cloud services > gradual reduction of It isolated applications on a production level by use of platform solutions > Integration of sap business systems with applications in production control > Integration of sap mII & sCm > mes as a comprehensive integration platform: with descriptive real-time and detailed information from production, making business processes faster and more flexible > Batch record standardisation: how batch records were first standardised on paper before going electronic > mes in emerging Countries / BrIC gmp requirements for application

    dr. peter Iles-smith mes technical dIrector - global manufacturing & supply GlaxoSmithKline plc / UK Carson sublett vice president operations & site director DSM Pharmaceuticals / The Netherlands Christoph lebl associate director automation Genentech Inc., Hillsboro, OR / USA paul kelly mes director Corporate operations Genzyme Industrial Affairs IS / Ireland dr. Bernd lehle director Biopharma electronic management systems Boehringer Ingelheim Pharma GmbH & Co. KG / Germany mark mckechnie lead mmdIt / global services MSD Carlow Site / Ireland michele vecchi head of manufacturing Information system Chiesi Group / Italy laura lei director, global technology group Baxter BioScience / USA stefan tautscher global head It Intercell AG / Austria Jens seest head of department for Quality assurance It Compliance LEO Pharma A/S / Denmark dr. anke meyer Business unit director pharma and md&d Janssen-Cilag AG / Switzerland mehron mirian Csv lead B.Braun Medical Inc. / USA marcel de grutter head of It portfolio management epo Abbott Healthcare Products B.V. / The Netherlands marian phelan sap / mes / material management lead Merck Sharp & Dohme / Ireland John dzelme senior systems analyst Roche Diagnostics / Switzerland nirav patel manufacturing systems engineer Bristol-Myers Squibb / USA Johann wieser head automation & mes F. Hoffmann-La Roche AG / Switzerland Brian duran Is project leader Sanofi Pasteur / France

    BUSINESS PARTNERS

    we.CONECT business peers take advantage of solution-oriented individual meetings that we can arrange with these partners before and during the conference.

    researChed & developed By

    http://pharma-mes.we-conect.com

    page 2 / 9

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    CONTENTS
    p. 2 | overview speakers main topics | icebreaker Icebreaker session Business partners media partners

    aGenda

    icebreaKer session | sunday, 23 rd septemBer 2012

    we.conect icebreaKer
    our Icebreaker session consists of small round tables with speakers, business partners and attendees where the audience will discuss the main challenges and cutting edge topics of the conference in a relaxed atmosphere. glass in hand, make your way around our round tables and get to know each other. enjoy food and drinks at the opening of the conference, break the ice and get the show on the road.

    p. 3

    p. 4-5 | conference day 1 Challenge your peers evening session p. 6-7 | conference day 2 world Caf

    20.00 | round tables Pre-conference drinks and Icebreaker Round Tables with speakers, business partners & participants

    ICeBreaker round taBle 1

    Quality by Design QbD in MES-Concept How companies deal with QbD, what are their challenges and new proposed approaches from ISPE Mehron Mirian, Csv lead, B.Braun Medical Inc. / USA

    ICeBreaker round taBle 2 ICeBreaker round taBle 3

    Manufacturing Intelligence through coupling BI and process improvement

    Performance Management Benchmark, Practices and Roadmap

    BUSINESS PARTNERS
    Enterprise System Partners acorn Business Campus | mahon Industrial park | Blackrock | Cork mr. dermot oCallaghan phone: +353 87 832 8905 | email: dermot.ocallaghan@esp.ie www.EnterpriseSystemPartners.com

    HALFMANN GOETSCH PEITHER AG st. alban-vorstadt 94 | Ch-4052 Basel, switzerland phone: +41 61 544 00 00 | email: info@hgp.ag www.hgp-pharma-consulting.com

    we.CONECT business peers take advantage of solution-oriented individual meetings that we can arrange with these partners before and during the conference.

    MEDIA PARTNERS
    produCtIvIty management is a felicitous relaunch of the former successful pps management competence in production and logistics. the concept of produCtIvIty management is characterized by high-value information with long lasting effect, by a close contact to editorial contents in print and on the internet and as well a unique forum, which includes considerable scientists, opinion formers, business practitioners, consultants and analysts for futureorientated trends. www.productivity-management.de

    researChed & developed By

    http://pharma-mes.we-conect.com

    page 3 / 8

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    aGenda
    8.00 8.45

    conference day 1 | monday, 24th septemBer 2012


    | registration with coffee and tea | welcome and introduction by we.ConeCt, the Chair and the advisory Board

    we.conect strateGy tracK


    Sustainable strategies for improving efficiency, productivity and compliance by implementing comprehensive data- and information platforms
    9.00 | Case study Flexible MES Architecture in a changing business environment > general pharma trends: less blockbusters, more specialized drugs, more biotech > past / present: Classical big biotech mes architecture > future: flexible mes architecture to support more and smaller products > special challenges for a contract manufacturer > plans with werum pas-x 3 Dr. Bernd Lehle, director Biopharma electronic management systems, Boehringer Ingelheim Pharma GmbH & Co. KG / Germany 9.40 | Case study Challenges in managing Automation & MES & reducing complexity dont Forget the Human Element > youve invested significantly in automation & control systems > the justification for the expenditure is not being realized > how much was invested in operator influence of the system? > operator training & awareness > Invest in the Culture to realize the improvements expected > Challenges in managing automation & mes & reducing complexity dont forget the human element Carson Sublett, vice president of operations & site director, DSM Pharmaceuticals / USA 10.20 | refreshment break with networking Zone

    we.conect inteGration tracK (1)


    Bridging the gap between traditional plant floor automation systems and business applications such as Enterprise Resource Planning (ERP), SAP, LIMS, SAP MII, SCM, Track & Trace
    10.50 | Case study Advance from Paper to Process Leverage MES to Analyze Plant Floor Data for Reporting and KPI Metrics > tactical strategies for implementing control points and an analysis framework to track and trend plant-floor data > transform plant floor data into a strategic analysis tool > tools to track oot / oos and equipment data > how to integrate data into a common database for analysis > Integrating control points in the process to analyze manufacturing data > ways to track and trend ranges and control points > detect anomalies in real-time Tba 11.30 | Case study MES Design, implementation, upgrade and gobal rollout (including packaging, warehouse and distribution, interfaced serialised product with MES, ERP and EPCIS systems) @ Genzyme Paul Kelly, mes director Corporate operations, Genzyme Industrial Affairs IS / Ireland 12.10 | Case study Implementing a fully paperless solution involving end to end process integration between MES and ERP, LIMS, asset, and training management systems and standardization on a global level > global mes rollout strategy to minimize project expenses and risks while maximizing resource productivity > standard Integration model aligning business processes across the organization > maintenance of reusable recipe objects and integration data flows across various distinct manufacturing sites > defining the roles and interactions for pat and serialization in the mes realm Nirav Patel, manufacturing systems engineer, Bristol-Myers Squibb / USA 12.50 | lunch with networking Zone

    we.conect processinG tracK (1)


    Manufacturing Execution Systems: Technical and organizational requirements and Selection Suitable Systems
    14.00 | Case study Software-Qualification & Validation from the perspective of Industry Ensuring high quality software in the Fast Track environment Johann Wieser, head automation & mes, F. Hoffmann-La Roche AG / Switzerland

    researChed & developed By

    http://pharma-mes.we-conect.com

    page 4 / 8

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    aGenda

    conference day 1 | monday, 24th septemBer 2012

    we.conect compliance & Validation tracK


    14.40 | Case study Security for Manufacturing IT Infrastructure and the Cloud Concept IT Control and Compliance Jens Seest, head of department for Quality assurance It Compliance, LEO Pharma A/S / Denmark 15.20 | Case study Effective MES implementation costs, benefits, justification and the people dimension > Identifying the cost drivers in mes projects > Business change and the impact of the people dimension on cost and schedule > hidden benefits or why the users may come to love the system Dr. Peter Iles-Smith, mes technical director, GlaxoSmithKline plc / UK 16.00 | refreshment break with networking Zone

    we.conect challenGe your peers what would you do?


    In these round tables, each with one moderator, the participants interact, describe & discuss their specific issues, approaches and solutions regarding the conference topic. we.CONECT finds out in advance the most important issues facing the participants. 16.30 | parallel round tables Based on your input, we will create these Round Tables involving an interactive discussion with your peers.

    we.conect processinG tracK (2)


    Improving Quality & Compliance and increasing Operational Excellence with Manufacturing Execution Systems
    17.20 | Case study Tracking of Product Contact Components in sterile manufacture / Traceability of components and management through MES / SAP > Benefits / business case for tracking of components > mes & sap Interface management > tracking of single use parts / tracking of reusable parts > technology, system validation & Compliance > lean manufacturing Quality & regulatory Compliance > factors for success Marian Phelan, sap / mes / material management lead, MSD / Ireland 18.00 | Case study Enabling Operational Excellence with MES Solutions that Drive Continuous Improvements > leverage mes and machine data to reduce machine change over times > visualize the value chain to reduce lead times > understand how certain tools in mes can be used to increase throughput while maintaining quality > utilize the integration of mes with other systems to reduce inventory and the administrative effort of replenishment John Dzelme, senior systems analyst, Roche Diagnostics / Switzerland

    dInner In a relaxed atmosphere to ConClude the fIrst ConferenCe day


    20.00 | networking dinner

    researChed & developed By

    http://pharma-mes.we-conect.com

    page 5 / 8

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    aGenda
    8.40

    conference day 2 | tuesday, 25th septemBer 2012


    | welcome and introduction by we.ConeCt, the Chair and the advisory Board

    we.conect world caf


    The World Caf will be initiated with short statements
    9.00 | short statement roI Caf I Develop an ROI program for an MES and engage project leaders and stakeholders with long-term goals of their manufacturing execution process > how can we make a truly paperless production a reality in the regulated environment? > what is the best approach to bridge the gap between enterprise systems and the shop floor automation? > high automation / Integration and high flexibility: are these conflicting priorities for an mes implementation? > how does the architecture and system landscape for the future look like > key success factors: who and what do we need to consider for a successful implementation? Dr. Anke Meyer, Business unit director pharma and md&d, Janssen-Cilag AG / Switzerland 9.05 | short statement processing & Integration Caf Process & Manufacturing IT harmonization of multiple sites to improve product quality and achieve excellence in manufacturing operations > what are the benefits to have harmonized process cross manufacturing sites? > how to understand, identify & manage the differences among facilities? > which are the right strategies & methods to harmonize processes (business) and It? > what are the key challenges during implementation? (data security and validity / language to be used / equipment variation, tolerance differences (ended up with smaller data than desired) Laura Lei, director, global technology, Baxter BioScience / USA 9.10 | short statement training & development Caf Training through the project lifecycle: > mes awareness training during project initiation (level set expectation and provide your core team with the knowledge they need to scope the project) > mes competency training prior to design (expand the core team and educate smes) > exploratory testing during development (Build a ground swell for your project and educate your future validation testers) > Implementation specific training prior to validation (give your testers the information they need to execute effectively and enable your team to write more generic test scripts) > training for roll-out (design your strategy to meet your organizational needs and available systems keep focus on key objectives of training and also on defendable compliance positions) Brian Duran, Is project leader, Sanofi Pasteur / France 9.15 | short statement roI Caf II Successfully Implementing MES: Its Not Turn the Key & Go! Saving time and money by ensuring management buy-in from the start > ensuring that mes is seen as a highly useful tool at a facilitys disposal and not just another technical system > realising that the majority of faults arise from poor management and organisation and not from the technology itself > ensuring consistent communication between operator and management in mes success > evaluating facility-specific priorities in software implementation > how to deal with cultural impact on the organization > Interfacing between erp and mes Marcel de Grutter, head of It portfolio management epo, Abbott Healthcare Products B.V. 9.30 | start world caf | each session lasts 40 minutes we.ConeCt and the chair open the world Caf, explaining the principles and set the world Caf etiquette.
    roi caf i processing & integration caf training & development caf roi caf ii

    12.10 | world Caf panel discussion Presentation of the key results of the World Caf and the individual interviews 12.30 | lunch with networking Zone

    researChed & developed By

    http://pharma-mes.we-conect.com

    page 6 / 8

    mes & process minds 2012 24 th 25 th septemBer 2012 | novotel BerlIn am tIergarten

    aGenda

    conference day 2 | tuesday, 25th septemBer 2012

    we.conect inteGration tracK (2)


    Global & Local Harmonization of MES and related applications & systems
    14.00 | Case study Integrating GMP production control and business process applications IT infrastructure design and operation > lean It infrastructure supporting validated and business related processes > design, setup and qualification > manage the operation of mixed gmp and non-gmp environments > security vs. process integration: enable interaction of mes with other systems while not jeopardizing your system integrity Stefan Tautscher, global head It, Intercell AG / Austria 14.40 | Case study MES Implementation to Go-Live at a Greenfield Vaccines and Biologics Manufacturing Facility Mark McKechnie, lead mmdIt / global services, MSD Carlow Site / Ireland 15.20 | refreshment break with networking Zone 15.50 | Case study How a mid-sized company has achieved an additional competitive advantage through the tight integration of their EBR / MES and their Automation System > mes totally integrated with plant automation layer > mes totally paperless > mes integrated with erp > gain in efficiency and saving personnel Michele Vecchi, head of manufacturing Information system, Chiesi Group / Italy 16.30 | Case study System Obsolescence the Road to a New MES / Migration of an MES > 4 years after building a green field fill-finish facility the mes is already obsolete > maintaining ongoing day-to-day manufacturing while migrating to a new mes > Competing for resources with a similar project at the same company but different site > Building the business case migrating a 4 year old system Christoph Lebl, associate director automation, Genentech Inc., Hillsboro, OR / USA 17.10 | Closing words from the chair and end of the conference

    REFERENCES OF OUR PAST CONFERENCES Great event & interactive sessions!


    Ben Hopkins, DSM / USA

    Creating new connection!


    Marc Labaille, Solvay / France

    Very interesting due to many fields and topics covered!


    Dr. Horst Rschert, Ticona GmbH / Germany

    I certainly enjoyed the sections and sessions top organisation & conference!
    Kaveh Pourteymour, BP / UK

    Many thanks to the whole we.conect team, a well prepared and executed conference in a new and modern style!
    Carsten Schmidt, Siemens Automation / Germany

    Perfect background of participants!


    Dr. Wolfgang Rybczynski, SAP / Germany researChed & developed By

    http://pharma-mes.we-conect.com

    page 7 / 8

    for more detailed information aBout our speakers and InteraCtIve segments please vIsIt http://pharma-mes.we-conect.com we are lookIng forward to welComIng you!

    researChed & developed By

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