MCQs in Biochemistry

06/06/2012 MCQs in Biochemistry
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CARBOHYDRATESANDCARBOHYDRATEMETABOLISM
$ % $ * ) ! * " / $ ! " * ` ` * 2 %) # 2 * 0 ` !
! 3 + ! / ! %) + 4 - 0 1 / ! &%) . ! ! " % %! ) 4
(A) IncreasedlevelsoflactateintheR.B.C
(B) Hemolyticanemia
(C) DecreasedratioofADPtoATPinR.B.C
(D) Increased phosphorylation of Glucose to
Glucose-6-phosphate
$ % $ * ) ! * " / $ ! " * ` ` * 2 %) # . / / ! ( ! ) / .
* ) ! - ) %) # # ` 0 * . ! ( ! / * ` %. ( %. * - - ! /
(A) TheconversionofGlucosetolactateoccurs
onlyintheR.B.C
(B) Glucoseentersmostcellsbyamechanismin
whichNa
+
andglucoseareco-transported
(C) Pyruvate kinase catalyses an irreversible
reaction
(D) An elevated level of insulin leads to a
decreasedleveloffructose2,6-bisphosphate
inhepatocyte
$ % $ * ) ! * " / $ ! " * ` ` * 2 %) # * ( + * 0 ) .
) ) * / # %1 ! - %. ! / * / $ ! ) ! / . 4 ) / $ ! . %. * "
` 0 * . !
(A) Lactate (B) Glycerol
(C) -ketoglutarate (D) Acetyl CoA
$ % $ * " / $ ! " * ` ` * 2 %) # - ! / %* ) . %. 0 ) %, 0 !
/ * # ` 0 * ) ! * # ! ) ! . %.
(A) LactatePyruvate
(B) Phosphoenolpyruvatepyruvate
(C) Oxaloacetatephosphoenolpyruvate
(D) Glucose-6-phosphateFructose-6-phosphate
$ ! . 4 ) / $ ! . %. * " # ` 0 * . ! " - * ( + 4 - 0 1 / !
4 # ` 0 * ) ! * # ! ) ! . %.
(A) Requirestheparticipationofbiotin
(B) Occursexclusivelyinthecytosol
(C) Isinhibitedbyelevatedlevelofinsulin
(D) Requiresoxidation/reductionofFAD
$ ! * ) 1 ! - . %* ) * " + 4 - 0 1 / ! / * ! / 4 ` *
)

(A) Isreversible
(B) Involvestheparticipationoflipoicacid
(C) Dependsonthecoenzymebiotin
(D) Occursinthecytosol
. / ! 0 - ! " " ! / %.
(A) Inhibitionofglycolysis
(B) Oxygenisinvolved
(C) Inhibitionofenzymephosphofructokinase
(D) Allofthese
* 2 ( ) 4 . - ! + - * 0 ! %) / $ !
* ) 1 ! - . %* ) * " + $ * . + $ * ! ) * ` + 4 - 0 1 / ! / *
%/ - / !
(A) 1 (B) 2
(C) 4 (D) 6
! 0 ! # ` 0 / / $ %* ) ! " 0 ) / %* ) . %) .
/ *
(A) ProduceNADPH
(B) Reducemethemoglobintohemoglobin
(C) ProduceNADH
(D) ReduceoxidizingagentssuchasH
2
O
2
$ ! ) 4 ` ` ) %) ! %. / $ ! + - ! 0 - . * - * "
(A) L-DOPA (B) Histamine
(C) Tyrosine (D) Throxine
) ) * . ! %. + - ! . ! ) / %) . * ( ! + ` ) /
+ - * 0 / . ` %&!
(A) Resins (B) Pectins
(C) Mucilage (D) Gums
` / * . ! %. ( %) * ) . / %/ 0 ! ) / * "
(A) Milk sugar (B) Honey
(C) Cane sugar (D) Chitin
` 0 * . ( %) ! %. ) %( + * - / ) / * ) . / %/ 0 ! ) /
* "
(A) Homopolysaccharide
(B) Heteropolysaccharide
(C) Mucopolysaccharide
(D) Dextran
` 4 * # ! ) %. + - ! . ! ) / %) ` ` * 4 / %. . 0 ! .
! 3 ! + /
(A) Liver (B) Brain
(C) Kidney (D) Stomach
* %) ! / ! . / %. + * . %/ %1 ! " * - . / - $ ! 3 / - %) )
(A) Mucoproteins (B) Agar
(C) Glycogen (D) Cellulose

MCQsINBIOCHEMISTRY
284. Thegeneralformulaforpolysaccharideis
(A) (C
6
H
10
O
5
)
n
(B) (C
6
H
12
C
6
)
n
(C) (C
6
H
12
O
5
)
n
(D) (C
5
H
10
O
5
)
n
285. Epimersofglucoseis
(A) Fructose (B) Galactose
(C) Ribose (D) Deoxyribose
286. Humanheartmusclecontains
(A) D-Arabinose (B) D-Ribose
(C) D-Xylose (D) L-Xylose
287. The intermediate n hexose monophos-
phateshuntis
(A) D- Ribulose (B) D-Arabinose
(C) D-xylose (D) D-Lyxose
288. On boiling Benedicts solution is not
reducedby
(A) Sucrose (B) Lactose
(C) Maltose (D) Fructose
289. Thedistinguishingtestbetweenmonosac-
charidesanddissaccharideis
(A) Bialstest (B) Seliwanoffstest
(C) Barfoedstest (D) Hydrolysistest
290. Barfoedssolutionisnotreducedby
(A) Glucose (B) Mannose
(C) Sucrose (D) Ribose
291. Coricycleis
(A) Synthesisofglucose
(B) reuseofglucose
(C) uptakeofglycose
(D) Both(A)&(B)
292. Canesugarisknownas
(A) Galactose (B) Sucrose
(C) Fructose (D) Maltose
293. Whichof thefollowingis not reducing
sugar?
(A) Lactose (B) Maltose
(C) Sucrose (D) Fructose
294. D-Glucoseand D-glucosearerelated
by
(A) Epimers (B) Anomers
(C) Multirotation (D) Ketoenolpair
295. The stable ring formation inD-Glucose
involves
(A) C-1andC-4 (B) C- 1andC-2
(C) C-1andC-5 (D) C- 2andC-5
296. ReductionofGlucosewithCa
++
inwater
produces
(A) Sorbitol (B) Dulcitol
(C) Mannitol (D) Glucuronicacid
297. Starchandglycogenarepolymersof
(A) Fructose (B) Mannose
(C) D-Glucose (D) Galactose
298. Reducingabilityofcarbohydratesisdue
to
(A) Carboxylgroup (B) Hydroxylgroup
(C) Enediolformation (D) Ringstructure
299. Whichofthefollowingisnotapolymer
ofglucose?
(A) Amylose (B) Inulin
(C) Cellulose (D) Dextrin
300. Invertsugaris
(A) Lactose
(B) Mannose
(C) Fructose
(D) Hydrolyticproductofsucrose
301 The carbohydrate reserved in human
bodyis
(A) Starch (B) Glucose
(C) Glycogen (D) Inulin
302 Adissaccharidelinkedby -1-4Glycosi-
deiclinkagesis
(A) Lactose (B) Sucrose
(C) Cellulose (D) Maltose
36
of 301
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CARBOHYDRATESANDCARBOHYDRATEMETABOLISM 23

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MCQsINBIOCHEMISTRY 24
253. A 254. A 255. C 256. A 257. B 258. B
259. A 260. D 261. A 262. B 263. C 264. B
265. D 266. B 267. C 268. A 269. B 270. C
271. B 272. C 273. A 274. B 275. D 276. C
277. D 278. C 279. D 280. A 281. C 282. B
283. C 284. A 285. B 286. C 287. A 288. A
289. C 290. C 291. D 292. B 293. C 294. B
295. C 296. A 297. C 298. A 299. B 300. D
301. C 302. D

7.A Polysaccharides are polymers of monosac-
charides. They are of two types hompolysac-
charides that contain a single type of
monosaccharide(e.g .,starch,insulin,cellulose)
and heteropolysaccharides with two or more
differenttypesofmonosaccharides(e.g.,heparin,
chondroitinsulfate).
30.B Mutorotationreferstothechangeinthespecific
opticalrotationrepresentingtheinterconversionof
-and -anomersofD-glucosetoanequilibrium.
48.A Starch is a polysaccharidecomposed of D-
glucose units held together by -glycosidic
bonds,( 1 4linkages;atbranchingpoints
16linkages).
71.A Hyaluronic acid is the ground substance of
synovial fluid of joints. It serves as lubricants
andshockabsorbantinjoints.
93.A Theprocessofshiftingahydrogenatomfrom
onecarbontoanothertoproduceenediolsis
referredtoastautomerization.
117.A Mucopolysaccharides(commonlyknownas
glycosaminoglycans)areheteropolysaccharides
composedofsugarderivatives(mainlyamino
sugars and uronic acids). The important
mucopolysaccharidesincludehyaluronicacid,
heparin,chondroitinsulfate,dermatansulfate
andkeratansulfate.
141.B Molischtest: Itisageneraltestforthedetection
ofcarbohydrates.ThestrongH
2
SO
4
hydrolyses
carbohydrates(poly-anddisaccharides)tolib-
eratemonosaccharides.Themonosaccharides
getdehydratedtoformfurfural(frompentoses)
orhydroxymethylfurfural(fromhexoses)which
condense with -naphthol to form a violet
colouredcomplex.
163.A Seliwanoffs test: this is a specific test for
ketohexoses. Concentrated hydrochloric acid
dehydrates ketohexoses to form furfural
derivativeswhichcondensewithresorcinolto
giveacherryredcomplex.
187.A Rotherastest: Nitroprossideinalkalinemedium
reactswithketogroupofketonebodies(acetone
andacetoacetate)toformapurplering.This
testisnotgivenby -hydroxybutyrate.
203.D Twospecifictransportsystemsarerecognized
fortheentryofglucoseintothecells.
(a) Insulin-independenttransport: Thisisacarrier
mediated uptake of glucose which is not
dependentonthehormoneinslulin.Thisoperates
inhepatocytes,erythrocytesandbrain.
(b) Insulin-dependent transport: This occurs in
muscleandadiposetissue.
230.D Hexokinaseandglucokinaseareinvolvedin
thephosphorylationofglucosetoglucose6-
phosphate.Theenzymehexokinase,present
in almost all the tissues, catalyses the
phosphorylationofotherhexosealso(fructose,
mannose).IthaslowK
m
forsubstrates(about
0.1 mM) and is inhibited by glucose 6-
phosphate.Incontrast,glucokinaseispresent
inliver,catalysesthephosphorylationofonly
glucose,hashighK
m
forglucose(10mM)

CARBOHYDRATESANDCARBOHYDRATEMETABOLISM 25
andisnotinhibitedbyglucose6-phosphate.
251.D The three enzymes namely hexokinase (or
glucokinase), phosphofructokinase and
pyruvatekinase,catalyzingtheirreversible
reactionsregulateglycolysis.Amongthese,
phosphofructokinaseisthemostregulatory.It
isanallostericenzymeinhibitedbyATP,citrate
andactivatedbyAMPandPi.
275.D The inhibition of glycolysis by oxygen is
referredtoasPasteureffect.Thisisdueto
inhibitionoftheenzymephosphofructokinase
byATPandcitrate(formedinthepresenceof
O
2
)
291.D Thecycleinvolvingthesynthesisofglucosein
liverfromtheskeletalmusclelactateandthe
reuseofglucosethussynthesizedbythemuscle
forenergypurposesisknownasCoriCycle.
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