Aids

1. Specify basic mechanical factors which hamper penetration of infectious exciter in in organism in presence of the immunodeficient state. A) Integral skin cover. B) Mechanical deleting of contagium from an organism with secrets: spleens, then, by a secret, mucus of bronchial tubes. C) None of the indicated variants of answer. 2. What acidity of secret of sweat, greasy and mucus glands does matter for warning of penetration in the organism of infection at the immunodeficient state? A) A low value of is a sour environment. B) Neutral environment. C) A high value of - is an alkaline environment. 3. By determination of I.I. Mechnikov, what two types of cells are carry out capture and overcooking of of microorganisms is phagocytosis? A) Polimorphonuclear neutrophyls and macrophages. B) Eosinophyls and basophyls. C) Granulocyts and plasmatic cells. D) Micro- and macrophages. 4. High title of antibodies to streptolysinO is testify in behalf on which from the transferred pathosiss? A) Chronic glomerulonephritis. B) Revmatoidniy arthritis. C) A streptococcus infection is recently carried. D) System red . 5. What from the resulted assertions right does describe the mechanism of antiviral action of interferon? A) An interferon is formed by coverage of surface of cages, warning of virus thus. B) Interferon directly virus in a environment. C) An interferon is destroyed by a virus which gets in a cage. D) An interferon operates through the genome of cage, products of antiviral albumens. 6. Swift development of immune insufficiency at AIDS is conditioned: A. By the defeat of CD4by the virus of immunodeficit B. Joining of the second infection, conditioned de bene esse a pathogenic exciter C. By elimination of the virus of immunodeficit D. By none of the transferred mechanisms E. All of the transferred mechanisms 7. Define the possible ways of distribution of the purchased immunodeficit, conditioned RNKretrovirus. A. Sexual a way B. Parenteral way throe whole blood and its separate components transfusion C. Transplacental way from maser to the born D. By none of the transferred ways E. All of the transferred ways 8. Does observe at AIDS hypergammaglobulinaemia and the amount of B-cells i? A. Yes B. It is not C. In most cases D. In the minority of cases E. Only in at persons younger 60 years

9. Specify the most substantial clinical signs of AIDS: A) Pnevmocistna pneumonia B) Dyspepsia, lasting more than month C) Fever, lasting more than month D) The loss of weight more than on 10% E) Limfoadenopatiya F) None of the indicated signs. 10. What microorganisms more frequent can be by reason of lethal end at AIDS? A) Cytomegaloviruses B) Virus of Epshtane-Barr C) Virus of herpes simplex D) Candida albicance E) Cryptococes F) Toxoplazma G) Pnevmocysta caryni H) None of the indicated microorganisms Answers : 1 AB, 2 A, 3 D, 4 C, 5 D, 6 AB, 7 ABC, 8 C, 9 ABCDE, 10 ABCDEFG. 11. Leading role in defence new-born from an infection in the first years of life belongs... A) IgM. B) IgD. C) IgG. D) IgE. 12. Antirhesus -globulins are applied... A) For treatment of hemolytic new-born disease, related to incompatibility of mather and new-born rhesus. B) For the prophylaxis of rhesus conflict in the moment of the repeated births for rhesus-negative mathers. C) For treatment of staphylococcus infection, flu, wooping-cough. 13. All of the followings belong to oxygen-dependent bactericidal factors of phagocytes, except for: A) Peroxyd anion. B) Lizocim. C) Free hydroxil. D) Hydrogen peroxyd. 14. What from the indicated structural elements of flu virus can induce creation of antibodies which own the expressed protective activity against flu? A) Neyraminidaza. B) Hemagglutinin. C) Nucleinic acid. D) Capsid. 15. Antibodies, specific to virus flu hemagglutinin, neutralize this virus... A) By complement activating throw a classic way. B) Causing viruse aggregation. C) By inhybition of virus binting with cellular receptor and impreding of its penetration in the cell D) Dysfunction of viral neurominidase. 16. What factors of defence more frequent than all can be broken in immunodeficit? A) Mechanical defence of penetration of infectious agent in the organism. B) Humoral factors, which destroy infectious agent which got in the organism. C) Phagocytose factors.

D) None of the transferred variants. 17. Specify the typical ways of penetration of infection in the organism in expressed immunodeficient states. A) Ingalatory. B) Peroral. C) Parenteral. D) Transkutanious. E) Transplacental. F) Only inhalation and peroral. 18. How does stress influence on immunoreactions? A) Represses the reactions of - link of the immune system. B) Stimulates the reactions of T-link of the immune system. C) Represses the reactions of B-link of the immune system. D) Stimulates the reactions of B-link of the immune system. 19. What formations of the neuro-immune-endocryne system take part in realization of stress changes of the immune system? A) Cortex of cerebri. B) Hypothalamus - hypophysis suprarenal glands. C) Thyroid. D) All of transferred. 20. How does secretory activity of thymus change at diminishing of endogenous glucocorticoids level? A) Increased. B) Diminishes. Answers: 11 C, 12 B, 13 B, 14 B, 15 C, 16 ABC, 17 ABCDE, 18 AC, 19 AB, 20 A 21. Is setting of interferon and its inductors expedient in the early stages of AIDS? A) Yes. B) It is not. 22. Lethal complications as new formations and heavy infections are characteristic for: A) Stages of SPID-associated complex B) For actually AIDS 23. How characteristically asymptomatic virus presenting during many years for HIV-infection? A) Yes B) It is not 24. What from the indicated new formations are cause for the diagnosis of AIDS? A) Kaposhy Sarcoma in persons junior 60 years B) Osteosarkoma C) Bazalioma 25. Is it possible to diagnose AIDS, based only on a positive reaction ELISA? A) Yes B) It is not C) Not always 26. Specify an absolute sign on the basis of which it is possible to diagnose AIDS: A. Clinical displays of opportunisti infections

B. Lymphopenia at if helper-supressive coefficient less than 1 C. Enhance concentration of immunoglobulins of classes G and An D. Decrease reactivity to general use antigens E.. Kaposhi Sarcoma in persons junior 60 years 27. Clinical displays of opportunistic infections in patients with AIDS condition: A. By suppression of dallied type hypersensitiveness of B. By a brech of cytotoxic T-cells formation C. Diminishing of -helper efficiency D. By none of the indicated factors 28. What stage of AIDS development can be pathology of CNS? A. In a latent period B. On the stage of generalise lymphadenopathy syndrome C. In AIDS-association complex D. At actually AIDS E).None of transferred 29. What preparations do behave to antiviral, what is applied at AIDS? A. Azidotimidin, rybaverin,acyclovir. B. Suramin, adeninorabiosid,ankamicin. C. Geteropolianion-23. D. None of transferred E. All are transferred preparations 30.What immunomodulators preparations are used for treatment of AIDS? A. Levamisole. B. Izoprinozin. C. Timosinum. D. Imreg, interleikin-2. E. All from transferred preparations arent expedient to apply in AIDS.
Answers

21 A, 22 B, 23 A, 24 A, 25 C, 26 E, 27 BC, 28 ABCD, 29 ABC, 30 ABCD

31. An engineer which 3 years worked by the contract in Africa, last 2 years feeling itself satisfactorily, is hospitalized in the pulmonary department with complaints about a general weakness, nightly swetting, dry unproductive cough. In a blood test found out a lymphopenia. Specify the most expedient diagnostic tactic? A. Test on restory of nitroblue tetrazolium. B. Determination of complement activity. C. Determination of phagocytic index. D. Search of antibodies to HIV in the ELISA test and immunobloting method. E. Search of leucocytes activity 32. Does the virus of immunodeficit of man influence on formation of cytotoxic T-cell, mainly acts on -helpers? A) Yes B) It is not C) In rare cases 33. Immune answer in patients with viral infection is characterized: A) By the increase of interferon formation

B) Activating of cytotoxic T-cells C) Speed-up making of immunoglobulins A, M, G D) Forming of memory cells E). None of transferred 34. What diseases, caused fungi, are characteristic for patients, infected HIV? A) Candidosis with the defeat skin of foots, brushes and folds B) Candidosis with the defeat of esofageus C) Criptococosis with the defeat of lungs, CNS or disseminative infection D) All of the indicated diseases and displays 35. What pathologic stetes and diseases, related to immunosupression it is necessary to differentiate AIDS? A) With an innate immunodeficit B) With the malignant tumour of the lymphoreticular system C) With heavy albumin-power insufficiency D) With none of the transferred pathosiss 36. Specify the clinical stages of AIDS development: A) Inkubating period B) Syndrome of generalised lymphadenopathy C) AIDS-associated complex D) AIDS E) None of the transferred periods is the stage of AIDS 37. What symptoms are characteristic for the AIDS-associated complex? A) Generalised lymphadenopathy B) Loss of body wait C) Swatting, fever, cough D) Dyspepsia E) Leico-, lympho-, thrombocitopenia, violation of cellular immunity F) None of the transferred signs 38. Immunological inspections of patients carried out as: A) Single investigation of patient in admition in the clinic B) Twofold investigation of patient C) Immunological monitoring of the disease flow D) Immunological investigation in dynamics if immunothropic therapy is displaed. 39. Specify, what preparations are used at symptomatic treatment of AIDS? A) Antibacterial preparations. B) Antifungal preparations. C) Antiviral preparations. D) None of the transferred preparations. 40. A patient which completed a course 5 years ago treatment concerning hearth tuberculosis of lungs appealed at Antituberculosis dispanser for the removal from account. After control investigation, was determent, that before the positive reaction of Mantu became negative. To consider... A) Patient is recovered from tuberculosis. B) An active tubercular process is saved. C) The vaccination of BCG is rotined a patient. D) The immunodeficient state takes place (possibly, AIDS).
Answers : 31 D, 32 A, 33 BC, 34 BC, 35 ABC, 36 ABCD, 37 ABCDE, 38 CD, 39 ABC, 40 D.