a New York State Center for Advanced Technology at Columbia University

Biomedical Informatics Update 2012

February 2, 2012
Pfizer Headquarters
219 E 42nd St., New York, NY Conference Room (ground floor)

A one-day meeting for local and regional healthcare specialists to discuss advances, problems, and solutions in various medical informatics venues in the New York area. The session will provide an opportunity to meet and talk to leading specialists who are at the forefront of HIT practice and innovation. This event is organized by Columbia University's Center for Advanced Information Management* and Department of Biomedical Informatics and is hosted by Pfizer Healthcare Informatics.

*The Center for Advanced Information Management at Columbia University is a NYSTAR-sponsored Center for Advanced Technology

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630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196

Biomedical Informatics Update 2012

February 2, 2012
Pfizer Headquarters
219 E 42nd St., New York, NY Conference Room (ground floor)

Program Schedule
Time Event

8:30am 9:00am

Coffee, Pastries
Welcome and Introductions

Michael Cantor, MD, MA; Pfizer, Inc. Update Overview George Hripcsak, MD, MS; Columbia University Remarks on New York City Biomedical Technology Seth W. Pinsky NYC Economic Development Corporation Electronic Medical Records, Biobanks, and Personalized Medicine Erwin Bottinger, MD Where Are We With Implementing Health Information Exchange? Gilad Kuperman, MD, PhD BREAK An Update on the Primary Care Information Project and Population Health in NYC Jesse Singer, DO, MPH Evaluation of HIE Implementation: New Methods and Results from HEAL NY Phase 5 Jacqueline Merrill, RN, MPH, DNSc LUNCH Watsons Potential Impact on Medical Practice Part A: Herbert S. Chase, MD, MA Part B: Roberto Sicconi, Dr. Ing. Demo and Q/A Session Update on PACeR [Partnership to Advance Clinical Electronic Research] David A. Krusch, MD Looking to the Future: Biomedical Informatics Research, Training, and Practice Edward H. Shortliffe, MD, PhD Speaker/Attendee Mixer

9:15am

9:45am

10:15am 10:45am

11:15am

12:00pm 1:00pm

1:45pm

2:15pm

3:00pm

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630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196

Biomedical Informatics Update 2012

Speakers Profiles
Pf izer Host

Michael N. Cantor, MD, MA, FACP

Senior Director, Pfizer Biomedical Informatics Services Pfizer, Inc.
Michaels work at Pfizer focuses on finding innovative uses for clinical data; precision medicine; and drug safety. He also co-leads the Data Without Borders initiative within Pfizers Worldwide R&D Business Technology organization. Prior to joining Pfizer he was the Chief Medical Information Officer for the South Manhattan Network of NYCs Health and Hospitals Corporation, based at Bellevue Hospital in Manhattan. Trained as an internist, he continues to see patients at Bellevue and is a Clinical Assistant Professor of Medicine at NYU School of Medicine. He completed his residency and informatics (MA) training at the Columbia campus of New York Presbyterian Hospital.
CAIM Host

Erwin P. Bottinger, MD
Director, Charles R. Bronfman Institute for Personalized Medicine Professor, Nephrology and Professor, Pharmacology and Systems Therapeutics Mt. Sinai School of Medicine
Dr. Bottinger is a trained nephrologist and experimental biologist, and holds the Irene and Dr. Arthur Fishberg Professor of Medicine endowed chair at Mount Sinai School of Medicine since 2004. His research focuses on exploring and evaluating the translation of genetic and molecular information in medical practice. He is the Director of the Charles R. Bronfman Institute for Personalized Medicine at Mount Sinai and the principal architect of the Institutes Biobank since 2007. He served previously as Vice Chair for Research, Department of Medicine. In addition, Dr. Bottinger holds NIH-funded research grants in the area of mechanisms of kidney disease and diabetic complications. Dr. Bottinger was previously an Associate Professor of Medicine and Molecular Genetics at Albert Einstein College of Medicine in Bronx, New York, for six years. During his tenure at Albert Einstein he also held several hospital appointments, including Attending Physician in the Department of Medicine at Montefiore Medical Center and Jacobi Medical Center in the Bronx. Dr. Bottinger also served as Visiting Associate at the National Cancer Institute and Visiting Staff Physician in the Kidney Disease Section at the Warren Grant Magnuson Clinical Research Center of the National Institutes of Health in Bethesda, Maryland. Dr. Bottinger has published many scientific studies and has received several awards, including the Special Service Award from the National Cancer Institute and the Mellini Award for Excellence in Biomedical Sciences. In 2002, he was elected a member of the American Society for Clinical Investigation. Trained in Europe, Dr. Bottinger received his medical degree from Friedrich-Alexander Universitat School of Medicine in Erlangen, Germany. He moved to New York to pursue a residency in internal medicine at Cabrini Medical Center and later completed a clinical and research fellowship in nephrology at Massachusetts General Hospital and Harvard Medical School in Boston. In addition, he served as a research fellow at the National Cancer Institute, where he stayed on as a Visiting Associate for four more years. Dr. Bottinger joined Mount Sinai in 2004.

George Hripcsak, MD, MS

Vivian Beaumont Allen Professor and Chair of Biomedical Informatics

Director, Center for Advanced Information Management Columbia University

In addition to his Columbia roles, George is also Director of Medical Informatics Services for NewYork-Presbyterian Hospital. He is a boardcertified internist with degrees in chemistry, medicine, and biostatistics. He led the effort to create the Arden Syntax, a language for representing health knowledge that has become a national standard. Dr. Hripcsaks current research focus is on the clinical information stored in electronic health records. Using data mining techniques such as machine learning and natural language processing, he is developing the methods necessary to support clinical research and patient safety initiatives. As Director of Medical Informatics Services, he oversees a 7000-user, 3-millionpatient clinical information system and data repository. He is currently co-chair of the Meaningful Use Workgroup of HHSs Office of the National Coordinator of Health Information Technology. Its role is to define the criteria by which health care providers collect incentives for using electronic health records. Dr. Hripcsak was elected fellow of the American College of Medical Informatics in 1995 and served on the Board of Directors of the American Medical Informatics Association (AMIA). As chair of the AMIA Standards Committee, he coordinated the medicalinformatics community response to the Department of Health and Human Services for the health-informatics standards rules under the Health Insurance Portability and Accountability Act of 1996. Dr. Hripcsak chaired the National Library of Medicines Biomedical Library and Informatics Review Committee, and he is a fellow of the American College of Medical Informatics and the New York Academy of Medicine. He has served on several Institute of Medicine and National Academy of Sciences committees, and he has published over 200 papers.

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630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196

Biomedical Informatics Update 2012

Speakers Profiles (cont.)
Herbert Chase, MD, MA
Professor of Clinical Medicine (in Biomedical Informatics) Columbia University
For over thirty years, Herb Chase has been teaching clinical medicine and basic science to medical students, interns and residents, and junior and senior faculty at the Columbia University College of Physicians and Surgeons. He is a board certified Internist and Nephrologist who spent the early part of his career as a basic scientist. After shifting his interest from research to education, he directed and participated in several major medical school courses. In 2000 he left Columbia University and was appointed the first Deputy Dean for Education at Yale School of Medicine where he introduced several major programmatic changes. In 2006 he returned to Columbia to enter the Masters program in Biomedical Informatics as an NLM-funded Postdoctoral Fellow. Dr. Chase has been recognized for his outstanding teaching with many awards including the Presidential Teaching Award of Columbia University.
Dr. Chase is currently a Professor of Clinical Medicine (in Biomedical Informatics) involved in several research projects: developing informatics methods to detect chronic kidney disease in its earliest stages; developing just-in-time information-retrieval systems for clinicians at the point of care; implementing strategies for pharmacovigilance operating through the electronic medical record (EHR); and creation of a patient record summary in the EHR.

Jacqueline Merrill, RN, MPH, DNSc

Associate Professor of Clinical Nursing in Biomedical Informatics Co-Investigator, HITEC (Health Information Technology Collaborative) Associate Clinical Director, Center for Advanced Information Management Columbia University
Jackie is a public health nurse and public health services researcher. She holds a doctorate in nursing science with a concentration in public health informatics. Dr. Merrills public health experience includes six years with the New York City Department of Health and Mental Hygiene in the Bureau of School Health and the Office of Nursing and Quality Improvement. Prior to earning her doctorate she spent four years as project director of the Center for Health Policy, at the Columbia University School of Nursing. As a result of her experience in clinical care, public health practice, and policy research, she has a broad knowledge of healthcare issues and particular understanding of health information technology as it relates to public health systems. Dr. Merrills research is based on a complex adaptive systems paradigm. She works with local public health departments to improve organizational performance. This work applies network analysis and management science to provide evidence-based decision support for public health managers.
In October, Dr. Merrill completed an evaluation of the public health use cases implemented in Phase 5 of the Health Care Efficiency and Affordability Law for New Yorkers (HEAL-NY) Capital Grant Program. The goal of this multi-year program is to transform health care in NYS, in large part through health information technology. Dr. Merrills evaluation was part of the Health Information Technology Evaluation Collaborative (HITEC), the academic consortium led by Weill Cornell Medical College, which is the designated evaluation entity for health IT projects funded under the HEAL-NY initiative

He is the Principle Investigator on a $3.7 million grant, funded through the Office of the National Coordinator, for UniversityBased Training of Health Information Technology Professionals. He is also a medical advisor to the IBM team developing the medical version of Watson. He continues to develop new medical educational programs at Columbia where he is now implementing a four-year curriculum in medical decision-making and a capstone course in Biomedical Informatics.

David A. Krusch, MD
Director - Department of Medical Informatics Professor - Department of Surgery, Oncology and Professor Department of Medical Informatics University of Rochester Medical Center
Dave received his M.D. from the Johns Hopkins School of Medicine and then completed his residency and fellowship in surgery at the University of Virginia. His areas of specialty interest include gastrointestinal surgery, minimally invasive upper abdominal surgery, vascular access and surgical treatment of hematological diseases. Dr. Krusch is also the Director of the Department of Medical Informatics and the Chief Medical Information Officer. He has received several awards and honors, including the University of Rochester Medical Center Board Award for Excellence, 2003; Buswell Fellowship Award, University of Rochester School of Medicine and Dentistry University of Rochester School of Medicine and Dentistry, 1993; The Bigger-Lehman Award, Virginia Surgical Society Virginia Surgical Society.

Gilad J. Kuperman, MD, PhD

Executive Director, NYCLIX Director, Interoperability Informatics, NewYork-Presbyterian Hospital; Adjunct Associate Professor, Department of Biomedical Informatics, Columbia University
Gil is Executive Director of NYCLIX, a health information exchange organization that covers Manhattan and other parts of New York City. He is also Director for Interoperability Informatics at NewYork-Presbyterian Hospital. His role there is to help the hospital realize the benefits of interoperability internally, with its business partners and through participation in regional data interchange efforts. Dr. Kuperman is an Adjunct Associate Professor of Biomedical Informatics at Columbia University. He will be the Board Chair of the American Medical Informatics Association, AMIA, in 2012 and 2013. In 2010, he was Scientific Program Committee chair for the AMIA Annual Symposium, a conference on informatics which draws over 2000 people annually.

WWW.CAT.CO LU M BIA.EDU

630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196

Biomedical Informatics Update 2012

Speakers Profiles (cont.)
Edward H. Shortliffe, MD, PhD, MACP, FACMI
President and CEO, American Medical Informatics Association (AMIA)
Ted Shortliffe is President and CEO of the American Medical Informatics Association, based in Bethesda, MD. His academic appointment is as Adjunct Professor of Biomedical Informatics at Columbia Universitys College of Physicians and Surgeons. Previously he was Professor of Biomedical Informatics at the University of Texas Health Science Center in Houston and, before that, at Arizona State University. He also served as the founding dean of the Phoenix campus of the University of Arizonas College of Medicine. From 2000-2007 he was the Rolf A. Scholdager Professor and Chair of the Department of Biomedical Informatics at Columbia University and Professor of Medicine and of Computer Science at Stanford University (1979-2000). Dr. Shortliffe has spearheaded the formation and evolution of graduate degree programs in biomedical informatics at Stanford, Columbia, and Arizona State University. His research interests include the broad range of issues related to integrated decision-support systems, their effective implementation, and the role of the Internet in health care. He is an elected member of the Institute of Medicine, the American Society for Clinical Investigation, and the Association of American Physicians. He has also been elected to fellowship in the American College of Medical Informatics and the American Association for Artificial Intelligence. A Master of the American College of Physicians, he received the Grace Murray Hopper Award of the Association for Computing Machinery in 1976. Currently Editor-in-Chief of the Journal of Biomedical Informatics, Dr. Shortliffe has authored over 300 articles and books in the fields of biomedical computing and artificial intelligence. cryptographic systems for data security, a portable videoconferencing system for laptops. In 1998 he moved to the US to work as executive assistant to the GM of IBM Microelectronics, leading two cooperation projects with IBM Research (a speech chip and a Bluetooth chip). Dr. Ing Sicconi joined the Human Language Technology group at IBM T. J. Watson Research Center in 2000. There he managed development of exploratory prototypes of conversational and multimodal user interfaces in smartphones and other consumer devices (STB, videogames), with a special focus on cars, both in standalone and in network-connected configurations. Most recently he joined the DeepQA team to apply deep semantic analysis of very large unstructured information sources, hypotheses generation, multiple search and results scoring techniques to the Jeopardy! game and business Question Answering applications. Research projects are currently targeting differential diagnosis assistance in healthcare, technical support for agents in contact centers, customer technical support in financial services, and online videogaming. He coordinated speech activities and graphics display of the Watson avatar as part of the Jeopardy! Challenge.

Jesse Singer, DO, MPH

Assistant Commissioner for the Primary Care Information Project (PCIP) NYC Department of Health & Mental Hygiene (DOHMH).

Roberto Sicconi, Dr. Ing.

Program Director IBM T.J. Watson Research
Roberto received his MS degree from the Politecnico University of Milan, Italy and his Doctorate degree from the same University in 1985 in the area of image processing and new Computer Aided Design techniques. He joined IBM Italy in 1985 to work on development of multimedia platforms, both hardware and software, working on hardware acceleration for hi-resolution PC and RISC/6000 workstations, DSP-based front-ends for IBM speech recognitions systems on PCs, PS/2 and laptops. In 1990 he became manager of the Multimedia Development Lab at Vimercate, Italy, leading development of speech recognition products (Martin/Voicetype), high-throughput bank check image scanners, a high-resolution negative film scanner, TV-Teletext VBI receivers, high-speed modems, a satellite Internet data broadcasting system, IBM

Jesse is board certified in Public Health and Preventive Medicine. He joined PCIP in 2007 as the Director of Quality Informatics and in 2009 became PCIP's Executive Director of Development. He was responsible for overseeing the collaborations between health information technology vendors and PCIP to incorporate public health priorities and functions into these products. Such functions include quality measurement and population health surveillance, clinical decision support, health information exchange and interfaces with public health agencies. Dr. Singer is a frequent presenter and panelist, focusing on health information technology (HIT) as a means to improve public health. He conceptualized and led the development of the Hub, an innovative model for improving public health through a system integrated with EHRs, allowing rapid deployment of public health queries, a clinical decision support system, and secure provider communication. This system currently covers close to 2 million patients in NYC. PCIP received the 2011 HIMSS Public Health Davies Award of Excellence for its positive impact on population health through HIT innovations such as the Hub.

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630 West 168th Street, PH 1501, New York, NY 10032 Telephone: 212 305 2944 Facsimile: 212 305 0196

Biomedical Informatics Update 2012

Organizational Profiles
a New York State Center for Advanced Technology at Columbia University

Center for Advanced Information Management

630 West 168th Street, PH 1501, New York NY 10032 Telephone: 212 305-2944 www.cat.columbia.edu

In 1983, New York State established a Center for Advanced Technology (CAT) Program to promote the collaboration between its industry base and its major research institutions. The goal was to facilitate technology transfer and commercialization using the expertise and resources in academia to benefit companies economically. Currently, the program continues with 15 CATs at 13 institutions located around the state. Each CAT has a specific technology focus (http://www.nystar.state.ny.us/cats.htm) and approach to helping its partner companies. The CAT program is supported by Empire State Development, Division of Science, Technology and Innovation (a.k.a. NYSTAR). NYSTAR currently offers a range of programs to help promote the states technology base. Columbia Universitys Center for Advanced Information Management has been a participant in the CAT program since its inception. CAIMs focus is at the intersection of biomedical science, information technology, and biomedical imaging, with the occasional inclusion of other areas of biomedicine and information processing. Its main contributing units are the Department of Biomedical Informatics and the Center for Computational Biology and Bioinformatics, both at the medical center (College of Physicians and Surgeons), and the Computer Science Department and imaging group of the Department of Biomedical Engineering, both in the School of Engineering and Applied Science. This broad range of expertise serves CAIM well in allowing for innovative interdisciplinary projects involving specialists from both schools and campuses.

Department of Biomedical Informatics

622 West 168th St. VC5, New York, NY 10032 Telephone: 212 305-5334

Department of Biomedical Informatics

www.dbmi.columbia.edu
The Columbia University Department of Biomedical Informatics is among the oldest in the nation. Its goals are to discover new information methods, to augment the biomedical knowledge base, and to improve the health of the population. DBMIs 30 faculty members and 60 students work in a highly collaborative environment, applying informatics from the atomic level to global populations. Areas of application include: CLINICAL CARE. Design clinical information systems and mine the electronic health record. BIOLOGY. Includes systems biology, structural biology, and virology, on studies in partnership with the Center for Computational Biology and Bioinformatics. PUBLIC HEALTH. Design systems to promote and protect the health of communities, improve public health systems, and deploy information technology internationally. TRANSLATIONAL RESEARCH. Integrate biological and clinical knowledge and facilitate multidisciplinary science.

Pfizer Incorporated
Pfizer applies science and its global resources to improve health and well-being at every stage of life. It strives to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines for people and animals. Pfizers diversified global health care portfolio includes human and animal biologic and small molecule medicines and vaccines, as well as nutritional products and many of the world's best-known consumer products. Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with its responsibility as the world's leading biopharmaceutical company, Pfizer also collaborates with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on it. To learn more, please visit www.pfizer.com. Pfizer has co-sponsored the medical informatics update since its inception.