DRUG NAME

MECHANISM OF ACTION

ADMINISTRATIO N

INDICATION & CONTRAINDICAT ION INDICATION:

ADVERSE EFFECT

NURSING RESPONSIBILITI ES Before administration, ask the patients mother if patient is allergic to penicillins or cephalosporins and verify thru skin test. If large doses are given, therapy is prolonged or patient is at high risk, monitor for signs and symptoms of superinfection Tell patients mother to report adverse reaction or signs and symptoms of super infection promptly Instruct patients mother to report discomfort at IV insertion site Advise patients

Generic Name: Ceftazidime Brand Name: Fortaz, Tazicef, Tazidime, Ceptaz

Classification: Anti-Infective Mode of Action Third generation cephalosporin that inhibits cell wall synthesis, promoting osmotic instability usually bactericidal.

Dosage: 470 milligram Route: TIV Frequency: Q8 ANST: (-)

Ceftazidime is a third generation cephalasporin that is used in the treatment of infections caused by mainly Gram Negative organisms like Enterobacter, Klebsiella and Proteus.It is highly active against pseudomonas aeuruginosa. CONTRAINDICAT ION: Ceftazidime is contraindicated in infants less than one month of age,renal disease, pregnancy, lactation and hypersensitivity .

CV: Headache CV: phlebitis, thrombophlebitis GI: nausea and vomitting, diarrhea

mother to notify prescriber about loose stools or diarrhea

DRUG NAME

MECHANISM OF ACTION

ADMINISTRATIO N

INDICATION & CONTRAINDICAT ION INDICATION:

ADVERSE EFFECT Paresthesia of limbs, flaccid paralysis, nausea, vomitting, abdominal pain, hypotension

NURSING RESPONSIBILITI ES Monitor VS Check potassium level after repeated doses. Inform patient of short-term need for drug and answer any questions and address concerns Review potential adverse reactions and instruct patient to promptly report

Generic Name: Potassium chloride Brand Name: Kalium Durule

Classification: Potassium salt Mode of Action: Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.

Dosage: 1 tab Route: Frequency: TID ANST: (-)

Hypokalemia. Prophylaxis during treatment w/ diuretics. CONTRAINDICAT ION: Renal insufficiency, hyperkalemia, untreated Addison's disease, constriction of the esophagus &/or obstructive changes in the alimentary tract.

any occurrences.

DRUG NAME

MECHANISM OF ACTION

ADMINISTRATIO N

INDICATION & CONTRAINDICAT ION INDICATION:

ADVERSE EFFECT

NURSING RESPONSIBILITI ES Assess for infection (vital signs, appearance of wound, sputum, urine, and stool; WBC) at beginning of and during therap. Ask about antibiotic allergy. Obtain specimen for culture and sensitivity before starting therapy

Generic Name: Ertapenem Brand Name: Invanz

Classification: Anti-infectives Mode of Action: Moderate to severe complicated skin infection Bactericidal action against specific aerobic gram-positive organisms.

Dosage: 1g Route: TIV soluset NSS 30 mins. Frequency: OD ANST: (-)

GI effects, injection-site INVANZ is reactions, raised indicated for the platelet count; treatment of adult less frequently patients and dry mouth, taste pediatric patients disturbances; (3 months of age hypotension, and older) with chest pain, the following pharyngeal moderate to discomfort, severe infections dyspnea, caused by dizziness, sleep susceptible disturbances, isolates of the confusion, designated seizures, microorganisms vaginitis, raised CONTRAINDICAT glucose; headache; ION: hypersensitivity

Hypersensitivity, cross-sensitivity reactions with penicillins, cephalosporins, and other carbapenems

reactions; antibioticassociated colitis; dysphagia; liver disorder; arrhythmia; syncope; nasal congestion; cough; wheezing; CNS effects; pelvic peritonitis; renal impairment; muscle cramp; blood disorders, hypoglycaemia; electrolyte disturbances.

DRUG NAME

MECHANISM OF ACTION

ADMINISTRATIO N

INDICATION & CONTRAINDICAT ION INDICATION:

ADVERSE EFFECT CNS: dizziness, drowsiness, fatigue, headache, vertigo CV: chest pain, palpitations GI: nausea, diarrhea, abdominal pain, cholestatic jaundice, dyspepsia,

NURSING RESPONSIBILITI ES Obtain specimens for culture and sensitivity testing before starting therapy Dont administer as IV bolus or IM injection Dilute solution using NSS or half-

Generic Name: Azithromycin Brand Name: Zmax, Zithromax

Classification: Macrolide Antiinfective Mode of Action: Bactericidal & bacteriostatic. Demonstrates cross-resistance

Dosage: 500mg Route: Frequency: 3 days ANST: (-)

Zmax (azithromycin) is indicated for the treatment with mild to moderate infections caused by susceptible isolates of the designated

to erythromycinresistant gram (+) strains and resistance to most strains of Enterococccus fecalis and methicillinresistant Staphylococcus aureus

microorganisms in the specific conditions listed below.

flatulence, melena GU: nephritis, vaginitis, candidiasis CONTRAINDICAT Metab: hyperglycemia, ION: hyperkalemia Skin: Zmax photosensitivity, (azithromycin) is contraindicated in rashes, angioedema patients with known hypersensitivity to azithromycin, erythromycin or any macrolide or ketolide antibiotic.

NSS, D5W, or LR Infuse over no less than 60mins. Infuse 1mg/mL over 3 hours or 2mg/2mL over 1 hr IV onset is rapid, peaks at end of infusion Monitor temp., WBC counts, and CS results Assess for s/sx of infection Monitor patients at risk for cardiac arrhythmia

DRUG NAME

MECHANISM OF ACTION

ADMINISTRATIO N

INDICATION & CONTRAINDICAT ION INDICATION:

ADVERSE EFFECT Severe allergic reactions such as rash, hives, itching, dyspnea, tightness in the chest, swelling of the mouth, face,

NURSING RESPONSIBILITI ES Unusual change in bleeding pattern should be immediately reported to the physician.

Generic Name: Tranexamic Acid Brand Name: Hemostan, Fibrinon,

Classification: Anti-fibrinolytic, antihemorrhagic Mode of Action: Tranexamic acid

Dosage: 500mg Route: TIV

Tranexamic acid Injection is indicated in patients with hemophilia for

Cyklokapron, Lysteda, Transamin

is a synthetic derivative of the amino acid lysine. It exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules. Antifibrinolytic drug inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots. The plasminogenplasmin enzyme system is known to cause coagulation defects through lytic activity on fibrinogen, fibrin and other clotting factors. By inhibiting the action of plasmin (finronolysin) the anti-fibrinolytic agents reduce excessive breakdown of

Frequency: ANST: (-)

short-term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction.

lips or tongue Calf pain, swelling or tenderness Chest pain, Confusion Coughing up blood Decreased urination

For women who are taking Tranexamic acid to control heavy bleeding, the medication should only be taken during the menstrual period. Tranexamic Acid should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed. The medication can be taken with or without meals. Swallow Tranexamic Acid whole with plenty of liquids. Do not break, crush, or chew before swallowing. If you miss a dose of Tranexamic Acid, take it when you remember,

CONTRAINDICAT Severe or ION: persistent headache Tranexamic acid Injection is Severe or contraindicated: persistent body malaise 1. In patients with Shortness of acquired breath defective color vision, Slurred speech since this prohibits Vision changes measuring one endpoint that should be followed as a measure of toxicity (see WARNINGS ). 2. In patients

fibrin and effect physiological hemostasis.

with subarachnoi d hemorrhage . Anecdotal experience indicates that cerebral edema and cerebral infarction may be caused by CYKLOKAPR ON (tranexamic acid) in such patients. 3. In patients with active intravascula r clotting.

then take your next dose at least 6 hours later. Do not take 2 doses at once.