DN8 CL1 kLVILW

SAMLL ULS1ICNS

Dk VAI8nAV 8nAkA1
Dk ISnAD AGGAkWAL
kALAM 8CCkS
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(1)1rue about boundar|es of |ngu|na| cana| are a|| LkCL1
(A) Con[olnL Lendon anLerlorly
(8) lascla Lransversalls ls posLerlor boundary
(C) lngulnal llgamenL forms base
(u) lnLernal obllque forms roof

AnSWL8(A) Con[olnL Lendon anLerlorly

8Ll Cray's anaLomy 39Lh edlLlon page 11091111
hLLp//enwlklpedlaorg/wlkl/lngulnal_canal

1o help deflne Lhe boundarles Lhe canal ls ofLen furLher approxlmaLed as a box wlLh slx
sldes noL lncludlng Lhe Lwo rlngs Lhe remalnlng four sldes are usually called Lhe anLerlor
wall posLerlor wall roof and floor

1hese conslsL of Lhe followlng


Super|or wa|| (roof)
lnLernal obllque

1ransversus abdomlnls
Anter|or wa||
Aponeurosls of exLernal obllque
Aponeurosls of lnLernal obllque (laLeral
Lhlrd of canal only)
Superflclal lngulnal rlng (medlal Lhlrd of
canal only)
INGUINAL CANAL
oster|or wa||
1ransversalls fascla
Con[olnL
Lendon (medlal Lhlrd
of canal only)
ueep lngulnal
rlng (laLeral Lhlrd of
canal only)

Infer|or wa|| (f|oor)
lngulnal llgamenL
Lacunar llgamenL (medlal Lhlrd of
canal only)
lllopublc LracL (laLeral Lhlrd of canal
only)

Cne way Lo remember Lhese sLrucLures ls wlLh Lhe mnemon|c MAL1 sLarLlng aL Lhe Lop and golng
counLerclockwlse
O , Muscles
O A Aponeuroses (1he A ln ,AL1 colncldes wlLh Lhe poslLlon of Lhe wallanLerlor 1hls can
be used Lo remember LhaL Lhe dlrecLlon of Lhe mnemonlc ls anLlclockwlse)
O L LlgamenLs
O 1 1ransversalls/1endon


(2) Marys |aw states the re|at|onsh|p of heart rate w|th?
(A) Cardlac ouLpuL
(8) SLroke volume
(C) ArLerlal 8
(u) resysLollc volume

AnSWL8 (C) ArLerlal 8

8Ll 1exLbook of racLlcal hyslology by Ck al al ravaLl 2
nd
edlLlon age 190

ulse raLe ls lnversely proporLlonal Lo Lhe blood pressure buL noL vlce versa 1hls ls called
,arys law

(3) naemog|ob|n synthes|s starts w|th?
(A) Clyclne
(8) PlsLldlne
(C) lron
(u) lollc acld

AnSWL8 (A) Clyclne

8Ll Parper 26
Lh
e p 271273

Steps of porphyr|n r|ng synthes|s

Lnzyme Locat|on substrate roduct porphyr|a

ALA synLhase ,lLochondrlon Clyclne succlnyl CoA
uAmlnolevullnlc
acld
none
ALA dehydraLase CyLosol uAmlnolevullnlc acld orphoblllnogen
ALA
uehydraLase
deflclency
8C deamlnase CyLosol orphoblllnogen
PydroxymeLhyl
bllane
AcuLe
lnLermlLLenL
porphyrla
uroporphyrlnogen lll
synLhase
CyLosol PydroxymeLhyl bllane
uroporphyrlnogen
lll
CongenlLal
eryLhropoleLlc
porphyrla
uroporphyrlnogen lll
decarboxylase
CyLosol uroporphyrlnogen lll
Coproporphyrlnogen
lll
orphyrla
cuLanea Larda
Coproporphyrlnogen
lll oxldase
,lLochondrlon
Coproporphyrlnogen
lll
roLoporphyrlnogen
lx
Coproporphyrla
roLoporphyrlnogen
oxldase
,lLochondrlon
roLoporphyrlnogen
lx
roLoporphyrln lx
varlegaLe
porphyrla
lerrochelaLase ,lLochondrlon roLoporphyrln lx Peme
LryLhropoleLlc
proLoporphyrla
neme synthes|snote that some react|ons occur |n the cytop|asm and some |n the m|tochondr|on
(ye||ow)

(4) Mutat|on |n kerat|n 1 and 10 are assoc|ated w|th?
(A) Lpldermolysls bullosa slmplex
(8) LpldermolyLlc hyperkeraLosls
(C) LpldermolyLlc palmoplanLar keraLoderma
(u) ,eesmann eplLhellal corneal dysLrophy

AnSWL8 (8) LpldermolyLlc hyperkeraLosls

8Ll !ournal of aLhology 2004 204 333366 uCl 101002/paLh1643

,uLaLlons ln keraLlns k1 and k10 are assoclaLed wlLh bullous congenlLal lchLhyoslform
eryLhroderma (8ClL) also someLlmes referred Lo as LP or LPk (epldermolyLlc
hyperkeraLosls Lhe prlnclpal cllnlcal feaLure of Lhls dlsorder)"

Mutat|ons of kerat|n (8emember aL leasL flrsL 2)
k3/k14 Lpldermolysls bullosa slmplex (L8S)
k1/k10 8ullous congenlLal lchLhyoslform eryLhroderma or
LpldermolyLlc hyperkeraLosls (LPk)
k9 LpldermolyLlc palmoplanLar keraLoderma
k6 k16 and k17 achyonychla congenlLa
k3/k12 ,eesmann eplLhellal corneal dysLrophy
k4/13 WhlLe sponge naevus

(S) As per "Drugs and cosmet|c act" prescr|pt|on drugs are |nc|uded |n?
(A) Schedule C
(8) Schedule P
(C) Schedule
(u) Schedule x

AnSWL8 (8) SecLlon P

8Ll lorenslc ,edlclne and 1oxlcology by 8n karmakar page age 42

As per drug and cosmeLlc rule 1943 urugs are classlfled lnLo dlfferenL schedule as follows
Schedu|e Drugs
Schedule C 8lologlcal and speclal producLs
Schedule L olsons
Schedule l vacclne and sera
Schedule C Pormone preparaLlons AnLl hlsLamlnes AnLlcancer
Schedule P urugs and polsons Lo be sold only by prescrlpLlon of a 8eglsLered medlcal
pracLlLloner
Schedule ! LlsL of dlseases for Lhe cure and prevenLlon of whlch no drug should be
adverLlsed (caLaracL epllepsy hydrocele bllndness eLc)
Schedule l AnLlbloLlcs and oLher recenL chemoLherapeuLlc agenLs


(6) er|phera| neuropathy not caused by wh|ch ant|retrov|ra| drug?
(A) Lamlvudlne
(8) uldanoslne
(C) Zldovudlne
(u) ZalclLablne

AnSWL8 (A) Lamlvudlne

8Ll Parrlson's 17
Lh
ed chapLer 182

S|de effects of some |mportant ant|retrov|ra| drugs

Ant|retrov|ra|
drug
Ma[or tox|c|ty
Zldovudlne Anemla granulocyLopenla myopaLhy lacLlc acldosls hepaLomegaly
wlLh sLeaLosls headache nausea
uldanoslne ancreaLlLls perlpheral neuropaLhy abnormallLles on llver funcLlon
LesLs lacLlc acldosls hepaLomegaly wlLh sLeaLosls
ZalclLablne erlpheral neuropaLhy pancreaLlLls lacLlc acldosls hepaLomegaly
wlLh sLeaLosls oral ulcers
SLavudlne erlpheral neuropaLhy pancreaLlLls lacLlc acldosls hepaLomegaly
wlLh sLeaLosls ascendlng neuromuscular weakness llpodysLrophy
Lamlvudlne

PepaLoLoxlclLy
Abacavlr PypersenslLlvlLy reacLlon (can be faLal) fever rash nausea
vomlLlng malalse or faLlgue and loss of appeLlLe
Lfavlrenz PepaLoLoxlclLy
uelavlrdlne Skln rash abnormallLles ln llver funcLlon LesLs

rotease |nh|b|tors
Sequanavlr ularrhea nausea headaches hyperglycemla faL redlsLrlbuLlon llpld
abnormallLles
8lLornavlr nausea abdomlnal paln hyperglycemla faL redlsLrlbuLlon llpld
abnormallLles may alLer levels of many oLher drugs lncludlng
saqulnavlr
lndlnavlr nephrollLhlasls lndlrecL hyperblllrublnemla hyperglycemla faL
redlsLrlbuLlon llpld abnormallLles
Amprenavlr nausea vomlLlng dlarrhea rash oral paresLheslas elevaLed llver
funcLlon LesLs hyperglycemla faL redlsLrlbuLlon llpld abnormallLles
AzLanavlr Pyperblllrublnemla 8 prolongaLlon nausea vomlLlng
hyperglycemla faL maldlsLrlbuLlon

(7) Mo|otov cockta|| |s?
(A) eLrol bomb
(8) ConLalns alcohol and coke
(C) used for Plv LreaLmenL
(u) ComblnaLlon of drugs used by coke addlcLs
AnSWL8 (A) eLrol bomb
8Ll lorenslc Sclence aL Work by !ay A Slegel !ay Slegel age 141
A ,oloLov cockLall ls also known as a peLrol bomb or alcohol bomb lL ls a slmple Lype of
lmprovlsed lncendlary devlce 1he slmplesL form conslsLs of a sLoppered boLLle fllled wlLh a
combusLlble llquld such as gasollne or hlghproof alcohol wlLh a fuelsoaked rag sLuffed ln
Lhe neck of Lhe boLLle


(8) |rst d|sab|||ty census was done |n the year?
(A) 1881
(8) 1931
(C) 1981
(u) 2001
AnSWL8 (A) 1881
8LlhLLp//censuslndlagovln/uaLa_roducLs/Llbrary/lndlan_percepLlve_llnk/PlsLory_llnk/c
ensushlsLoryhLm hLLp//censuslndlagovln/Ad_Campalgn/drop_ln_arLlcles/03
PlsLory_of_Census_ln_lndlapdf
llrsL general populaLlon census of lndla was done ln 1871 (noL rellable)
1he flrsL compleLe census of populaLlon was however conducLed ln 1881 on a
unlform basls LhroughouL lndla provldlng Lhe mosL compleLe and conLlnuous
demographlc record for any comparable populaLlon
Census AcL was passed ln 1948
1he flrsL census afLer lndependence was Laken ln 1931
lor Lhe flrsL Llme ln Lhe hlsLory of Census of lndla a Census ALlas was planned aL Lhe
SLaLe level as well as aL lndla level ln 1961 census
1he new feaLures of 1971 Census were
1 An aLLempL was made Lo collecL daLa on currenL ferLlllLy
2 ,lgraLlonal parLlculars wlLh reference Lo place of lasL resldence
3 A new concepL of SLandard urban Area was developed for Lhe LabulaLlon of
cerLaln urban daLa

ln 1981 Lhe quesLlon on dlsablllLy was canvassed for Lhe flrsL Llme and dropped ln
1971 relnLroduced ln 1981 and agaln dropped ln 1991
1he counLrys flrsL comprehenslve headcounL of menLally and physlcally challenged
people released on AugusL 9 2004 sLaLes LhaL Lhere were 21906769 dlsabled
people ln lndla ln !anuary 2001 1he census LhaL began a llLLle over Lhree years ago
puLs lndlas dlsablllLy raLe aL 213
Powever Census 2001 was conflned Lo dlsablllLy ln vlslon speech audlo movemenL
and menLal Census 2011 lncluded people wlLh mulLlple dlsablllLles


(9) Memory of Cu1 |s?
(A) 1 mlnuLe
(8) 2 mlnuLe
(C) 3 mlnuLe
(u) 4 mlnuLe
AnSWL8 (8) 2 mlnuLe
8Ll 1he ConLracepLlon Sourcebook by LllzabeLh 8 Connell page 138 ,edlcal [ournal of
AusLralla volume 2 volume 2 lssue 67
,emory of an luu devlce ls Lhe Llme Laken Lo regaln lLs orlglnal shape on lnserLlon
Lo Lhe uLerlne cavlLy
Loadlng Lhe luu lnLo Lhe lnserLer barrel should be fasL keeplng ln mlnd as Lhe plasLlc
wlll lose lLs memory afLer opproximote/y two minutes ln Lhe lnLroducer and wlll
noL regaln lLs orlglnal shape
nova1 was malnly developed Lo have a beLLer memory of shape Lhan Copper1
(10) In Downs syndrome 2nd tr|mester quadrup|e test |nc|udes a|| LkCL1
(A) Alpha feLoproLeln
(8) PCC
(C) lnhlbln A
(u) A

AnSWL8 (u) A

8Ll lernando arlas 3
rd
e p 4443

1he tr|p|e test measures Lhe followlng Lhree levels ln Lhe maLernal serum
1 AlphafeLoproLeln (Al)
2 Puman chorlonlc gonadoLropln (hCC)
3 uncon[ugaLed esLrlol (uL3)

1he levels may lndlcaLe lncreased rlsk for cerLaln condlLlons
A UL
3
hCG Assoc|ated cond|t|ons
low low hlgh uown Syndrome
low low low Lrlsomy 18 (Ldwards syndrome)
hlgh n/a n/a
neural Lube defecLs llke splna blflda assoclaLed wlLh lncreased levels of
aceLylchollnesLerase ln amlnonlc fluld or omphalocele or gasLroschlsls or
mulLlple gesLaLlon llke Lwlns or LrlpleLs

lurLhermore Lhe Lrlple LesL may be comblned wlLh an ulLrasound measuremenL of nuchal
Lranslucency

1he 1rlple LesL measures serum levels of Al esLrlol and beLahCC wlLh a 70 senslLlvlLy
and 3 falseposlLlve raLe lL ls complemenLed ln some reglons of Lhe unlLed SLaLes as Lhe
uad test (addlng lnhlbln A Lo Lhe panel resulLlng ln 81 senslLlvlLy and 3 falseposlLlve
raLe for deLecLlng uown syndrome)

Down's syndrome 1
sL
LrlmesLer 2
nd
LrlmesLer
Screenlng LesL nuchal Lranslucency +
beLa PCC + A le
comblned LesL
1rlple LesL (PCC + Al +uL
3
)
;uadruple LesL ( Lrlple LesL +
lnhlbln A)
ulagnosLlc LesL CvS AmnlocenLesls