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S1221 Dacarbazine
Technical Data:
M.Wt: Formula: Solubility: Purity: Storage: CAS No.: 182.18 C6H10N6O Unknown 99% at -20 2 years 4342-03-4
H2N N NH O N N N
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Synonyms:
DTIC, DTIC-Dome
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Biological Activity
Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.[1] Dacarbazine belongs to the family of chemicals known as alkylating agents. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.[2] Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse.[1]
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References
[1] http://en.wikipedia.org/wiki/Dacarbazine [2] http://www.cancer.gov/drugdictionary/?CdrID=39768
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Notes
PLEASE KEEP THE PRODUCT UNDER -20 FOR LONG-TERM STORAGE. NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products, stored under the recommended conditions, are stable for two years. Products are sometimes shipped at a temperature that differs from the recommended storage temperature,most are recommended stored at -20 Many products are stable in the short-term at temperatures that differ from that . required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save your shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage recommendations on the product data sheet.
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