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S1522 CHR-2797
Technical Data:
M.Wt: Formula: Solubility: Purity: Storage: CAS No.: 406.47 C21H30N2O6 Unknown 99% at -20 2 years 238750-77-1
HO HN O N H O OH O O
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Aminopeptidase
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Tech Support
tech@selleckchem.com
(chemistry support)
Synonyms: Tosedostat
techbio@selleckchem.com
(bio support)
Biological Activity
Tosedostat (formerly CHR-2797) is an aminopeptidase inhibitor with IC50 of 100, 150, 220, >1000, >5000, >10000 and >30000 nM for LAP, PuSA, aminopeptidase N, aminopeptidase B, PILSAP, LTA4 hydrolase and MetAP2, respectively. It has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel. [1][2]
Web
www.selleckchem.com
References
[1] Krige D et al. Cancer Res. 2008 Aug 15;68(16):6669-79 [2] Reid AH et al. Clin Cancer Res. 2009 Aug 1;15(15):4978-85
Return Policy
Please inspect packages immediately upon receipt and notify customer service within 3 days of delivery of any damage or discrepancies.Our team will take quick and appropriate action to correct any problem.
Goods ordered in error can only be accepted for return if made within 3 days of delivery, are unopened,have been stored correctly and are in good condition. Should you wish to return any item(s), prior authorization must
Notes
PLEASE KEEP THE PRODUCT UNDER -20 FOR LONG-TERM STORAGE. NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products, stored under the recommended conditions, are stable for two years. Products are sometimes shipped at a temperature that differs from the recommended storage temperature,most are recommended stored at -20 Many products are stable in the short-term at temperatures that differ from that . required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save your shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage recommendations on the product data sheet.
be received from our customer service team. Returns accepted will be subject to a 30% restocking charge.
For all product returns and product replacements,please contact Selleck directly by info@selleckchem.com or +1-713-922-4115 Please have on hand, the invoice number, purchase order number,air bill number and approximate date of shipment/receipt.