GPAT MODEL TEST-3

Question 1 of 100
Qualitative analysis by the polarography is based on

a) Electrode potential

b) Half wave potential

c) Migration Current

d) Limiting current

Question 2 of 100
DLVO theory is related to

a) Stability of emulsion
b)
c) stability of colloids
d)
e) Stability of suspension
f)
none

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Question 3 of 100
Nux vomica contains strychnine not less than

A) 2.3

B) 2.1

C) 1.2

D) 3.2

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Question 4 of 100
In coriander sativum; primary ridges are

A) 8 in numbers, prominent & straight

B) 8 in numbers, wavy & inconspicuous

C) 10 in numbers, wavy & inconspicuous

D) 10 in numbers, prominent & straight

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Question 5 of 100
Monsanto tester is used to test …….of the tablets.

A) Friability

B) Hardness

C) active content

D) disintegration

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Question 6 of 100
17, 21-Dihydroxy pregn-4-ene-3,11,20-trione is

A) Cortisone

B) Cholesterol

C) Progesterone

D) Aldosterone

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Question 7 of 100
Which is not characteristic of Gentian roots

A) Stone cells are absents

B) Starch grains are absents

C) Phloem fibers are

absent

D) Calcium oxlate crystals are absent

Question 8 of 100
A widely accepted detector electrode for pH measurement is

A) Platinum wire

B) Glass electrode

C) Ag-AgCl electrode

D) Lanthanum Florid electrode

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Question 9 of 100
1-oxopenam structure and has no 6-acylamino side chain of penicillin is
 A) Clavulanic acid

B) Impenam

C) Sulbactum

D) Carbpenam

Question 10 of 100
Microorganism used for obtaining dextran by fermentation is

A) Aspergillus oryzae

B) Aspergillus niger

C) Leuconostoc mesenteroids

D) Trichodermal reesii

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Question 11 of 100
Proenkephaline A is precursor of which one endogenous peptide

A) Leu-enkephaline

B) Dynorphine

C) Neonorphine

D) Beta-endorphine

Question 12 of 100
Which is the functional group transferred by coenzyme pyridoxal phosphate

A)amino

B)acyl

C)aldehyde

D)H-atom

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Question 13 of 100
Calcipotriene, a synthetic VitaminD3 analogue has the following attribute

A)Pronounced antirachitic activity

B) Pronounced antiscorbutic activity

 C) Used as a topical application in the treatment of moderate plaque psoriasis

D) Effect on calcium metabolism is 200 times more than ergocalciferol

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Question 14 of 100
Shinoda Test is used for

A) Tanin

B) Proteins

C) Flavonoids

D) Fat

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Question 15 of 100
Green bone is used in preparation of which type of gelatin

A) Type A

B) Type B

C) Both A and B

D) None of above

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Question 16 of 100
Inadequate spreading of the coating solution before drying is called as

A) Blistering

B) Cracking

C) Orange peel effect

D) Hazing

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Question 17 of 100
Which of the enzyme is not used in citric acid cycle

A) a-ketoglutarate dehydrogenase

B) Aconitase

C) Isocitrate dehydrogenase
 D) Carbonic anhydrase

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Question 18 of 100
…….is called as vibrational spectroscopy

A) IR-spectroscopy

B) UV-Visible spectroscopy

C) ESR

D) NMR

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Question 19 of 100
Partial or complete separation of top or bottom crown from tablet is termed as

A) Lamination

B) Sticking

C) Mottling

D) Capping

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Question 20 of 100
Licence of manufacture for sell or distribution of drugs other than those specified in
Schedules C, C1 and X

A) Form 24

B) Form 27

C) Form 26

D) Form 25

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Question 21 of 100
Decrease thickness of mucus and increase muco-ciliary movement are termed as

A) Antitussive

B) Mucolytic

C) Decongestant
 D) Expectorant

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Question 22 of 100
Carr Price reaction of vitamin A gives

A) Intense green

B) Intense violet

C) Intense blue

D) Intense red

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Question 23 of 100
Polarogram containing electroluminescent substance is obtained by plotting

A) Current vs Volume

B) Current vs Potential

C) Resistance vs Time

D) Potential vs Volume

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Question 24 of 100
Phenylethylamine and dicyanoamide (cyanoguanidine) are used to prepare

A) Phenformin

B) Chloroguanide

C) Cycloguanil

D) Metformin

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Question 25 of 100
"Athletics foot" disease is caused by

A) Fungus

B) Virus

C) Plasmodium
 D) Bacteria

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Question 26 of 100
A conductivity cell consist of

A)Two platinised platinum electrode

B) Platinum calomel electrode

C) Platinum tungsten electrode

D) Glass calomel electrode

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Question 27 of 100
Cedar wood oil is used in …….Magnification

A) 100x

B) 10x

C) 4x

D) 40x

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Question 28 of 100
One pair is incorrect

A) Anisocytic-cruciferous stomata

B) Paracytic-rubiaceous

C) Anomopcytic- ranunculaceous

D) Dicytic- irregular cell stomata

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Question 29 of 100
Which microorganism is used in the I.P. assay of Streptomycin?

A) Micrococcus luteus

B) Klebsiella peumoniae

C) Bacillus cereus

D) Staphylococcus epidermidis
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Question 30 of 100
In the double helical structure of DNA, A + G = T + C is given by

A) Avery-MacLeod-McCarty experiment

B) Hershey-Chase experiment

C) Nirenberg and Khorana's codon assignments

D)Chargaff's rules
Question 31 of 100
HLB range of o/w emulsifier is

A) 8 - 16

B) 4 - 6

C) 1 - 3

D) 7 - 9

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Question 32 of 100
Alpha-Glucosidase inhibitor used as oral hypoglycemic agent:

A) Guar gum

B) Acarbose

C) Troglitazone

D) Glucomannam

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Question 33 of 100
In normal healthy adult, blood urea concentration is

A) 20 mg/dL

B) 80 mg/dL

C) 100 mg/dL

D) 60 mg/dL

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Question 34 of 100
Immobilization of enzyme on self assembling nanocrystalline ceramic core is called

A) mesosome

B) aquasome

C) transfersome

D) neosome

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Question 35 of 100
Bancroft rule is used to study the stability of

A) Colloids

B) Suspension

C) solution

D) Emulsion

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Question 36 of 100
All enzymes are…….. in nature

A) Lipid

B) Protein

C) Carbohydrates

D) Lipopolysachharide

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Question 37 of 100
[2-chloro-11-(1-piperazinyl) dibenzo[b,f][1,4]oxazepine] is known as

A) Amoxapine

B) Quetiapine

C) Doxepin

D) Loxapine

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Question 38 of 100
Which of the following is water insoluble polymer?
 A) Hydroxypropyl methyl cellulose

B) Polyvinyl pyrolidone

C) Ethyl cellulose

D) Hydroxypropyl cellulose

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Question 39 of 100
Total number of Purine nucleotides is equal to total number of Pyrimidine nucleotides. This
according to

A) Watson & Crick model

B) Bohr's model

C) Chargaff'rule

D) none of these

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Question 40 of 100
Saponin glycoside is obtained from one of the followings

A) Roots of Picorrhyza kuroa

B) Dried roots of Asparagus racemosus

C) Dried leaves of Nerium oleander

Dried Bark of Rhamnus purshiana

Question 41 of 100
One of the following great name is related with magic bullet

A) Ehrlich

B) Pasteur

C) Sorenson

D). Fleming

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Question 42 of 100
The most abundant amino-acid present in the body is

A) Tyrosine
 B) Gultamine

C) Alanine

D) Aspargine

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Question 43 of 100
Iron content in gelatin should be not more than

A) 20 ppm

B) 15 ppm

C) 5 ppm

D) 10 ppm

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Question 44 of 100
which of the following is not 2,4,6- tri-iodo benzoic derivative organ imaging agent

A) diatizoic acid

B) Ioxaglate

C) Ipodate

D) metrizamide

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Question 45 of 100
Non protein part of conjugated enzyme is known as

A) Apoenzyme

B) Holoenzyme

C) Prosthetic group

D) Pseudoenzyme

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Question 46 of 100
The extrapyrimidal symptoms are the major side effects of

A) Typical neuroleptics
 B) Atypical neuroleptics

C) Tricyclic antidepressants

D) none

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Question 47 of 100
Hydroxylation of cyclopentene with KmnO4 results in

A) cis-1,2-cyclopentanediol

B) trans-1,2-cyclopentanediol

C) cyclopentanol

D) all

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Question 48 of 100
Which of the following nucleus present in Hydralazine?

A) Naphthalene

B) Pteridine

C) Aziridine

D) Phthalazine

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Question 49 of 100
Titrant used in IP assays of fluorouracil is

A) HClO4

B) TBAH

C) Sodium nitrite

D) Iodine

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Question 50 of 100
Enteric tablet coating material is

A) Hydroxypropyl methyl cellulose

B) Povidone
 C) Sodium carboxy methyl cellulose

D) Polyvinyl phthalate acetate

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Question 51 of 100
The first line drug for Burkett's lymphoma is

A) Actinomycine-D

B) Cyclophosphamide

C) Vinblastin

D) Dauxorubicin

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Question 52 of 100
A titration in which potential applied across two electrodes is maintained at a constant value
and the current is measured and plotted against volume of titrant is

A) Potentiometric titration

B) Amperometric titration

C) Displacement titration

D) Conductometric titration

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Question 53 of 100
Rat holing is problem during manufacturing of tablets is due to

A) Poor design of hoper

B) Higher processing temperature or humidity

C) Higher granule moisture content

D) Air entrapment

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Question 54 of 100
…. Amino acid shows fluorescence

A) Tryptophane

B) cysteine
 C) Serine

D) Glycine

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Question 55 of 100
Which one of the following is selective a2-antagonist?

A) Clonidine

B) Indoramine

C) Prazosin

D) Yohambine

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Question 56 of 100
In differential staining techniques, counter stain used is

A) gentian violet

B) crystal violet

C) neutral red

D) methyl violet

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Question 57 of 100
Buck Wheat is rich in

A) Fraxin

B) Rutin

C) Aesculetin

D) Scopoletin

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Question 58 of 100
St Johns wort is widely used in United States mainly as

A) Antioxidant

B) Antitussive

C) Antidepressant
 D) none of these

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Question 59 of 100
the number of peaks shown by cyclobutane in an NMR spectum is

A) One

B) Four

C) Five

D) Two

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Question 60 of 100
Canada balsam is used for

A) Fixing the section

B) Staining the section

C) Staining the starch grain

D) Staining the calcium oxalate crystal

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Question 61 of 100
All of the following drugs are thymidine inhibitors except

A) Triflouridine

B) Cytarbine

C) Vidarbine

D) Idoxuridine

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Question 62 of 100
Sodium cromoglycate has been developed from …molecule found in Ammi visnaga

A) Tubocuranin
 B) Physostigmine

C) Khellin

D) Morphine

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Question 63 of 100
Streptomycin has no useful activity in the treatment of

A) Tuberculosis

B) Brucellosis

C) Bubonic plague

D) Tularemia

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Question 64 of 100
Spans are chemically

A) Polysorates

B) Sorbitan esters

C) liposomes

D) none of these

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Question 65 of 100
Which of the following test is not applicable on parentral preparations?

A) Clarity test

B) Sterility test

C) Uniformity test

D) Pyrogen test

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Question 66 of 100
A typical auxin of plant, which is found in growing tissue is
 A) Indole-3-acetic acid

B) Gibberlin

C) Abscisic acid

D) None of these

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Question 67 of 100
The plasticizer used in capsule is

A) Mannitol

B) Sorbitol

C) PEG

D) Lactose

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Question 68 of 100
____ color is observed in Murexide test for ______ alkoids

A) Yelow, Indol

B) Blue, Imidazole

C) Purple, Purine

D) Green, Pyrrole

rythromycin acts by

A) combining with 50s-ribosome

B) combining with 30s-ribosome

C) Interfering with DNA synthesis

D) all of these

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Question 70 of 100
Tissue plasminogen activator that disperses blood clots, beneficial if it is given within

A) 9 hours

B) 24 hours
 C) 3 hours

D) 3 days

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Question 71 of 100
Porosity is defined as

A) the ratio of the void volume to the true volume

B) the ratio of the void volume to the bulk volume

C) the ratio of the true volume to the bulk volume

D) none of these

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Question 72 of 100
The pinene hydrochloride rearranged into bornyl terpenoid is called as

A) Pinacol rearrangement

B) Fries rearrangement

C) Beckmann rearrangement

D) Wagner-Meerwein rearrangement

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Question 73 of 100
The purity and acceptability of the propellant is tested by

A) Moisture

B) Halogen

C) Non volatile residue determination

D) All of these

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Question 74 of 100
Glutamate to GABA is converted by the enzyme

A) Kinase

B) Glutamate decarboxylase
 C) Maelic dehydrogenase

D) HMG-CoA

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Question 75 of 100
The volume (ml) required for a given size of "000" capsule is:

A) 0.75

B) 0.25

C) 0.95

D) 0.55

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Question 76 of 100
serum sample of a patient shows elevated levels of (SGOT) Serum-glutamyl-oxaloacetate
transferase. The Patient could be suffering from

A) Kidney disorder

B) Myocardial infarction

C) Parkinson's disease

D) Liver disorder

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Question 77 of 100
One of the following is not a Leukotriene synthatase inhibitor

A) Montelukast

B) Zafirlukast

C) Ziluton

D) Nedocromil sodium

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Question 78 of 100
Find the missing number 24:15::63:?

A) 28

B) 56
 C) 38

D) 48

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Question 79 of 100
Covering trichomes present in Datura are

A) Uniseriate unicellular

B) Biseriate unicellular

C) Biseriate multicellular

D) Uniseriate multicellular

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Question 80 of 100
which drug is used in hypertention that is angiotensin-II antagonist at AT1 receptor?

A) Hydralazine

B) Lisnopril

C) Telmisartan

D) Diazoxide
Question 81 of 100
presence of anomocytic stomata on the epidermis of pericarp and mesocarp containing
lignified and reticulate parenchyma

A) Nutmegh

B) Cardamom

C) Cinnamon

D) Fennel

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Question 82 of 100
Current vs. Potential curve is known as

A) Chromatogram

B) Polarogram

C) Cardiogram

D) none of these
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Question 83 of 100
In normal HPLC

A) Stationary phase is polar and mobile phase is non polar

B) stationary phase is non polar and mobile phase is polar

C) both phase are polar

D) both phase are non polar

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Question 84 of 100
One of the following is largest Cotton producing state in India

A) Maharasthra

B) Utter Pradesh

C) Gujarat

D) Rajasthan

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Question 85 of 100
The most stable conformation of Acetylcholine is

A) Trans

B) Guache

C) Eclipsed

D) all of these

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Question 86 of 100
The Ex-officio members of pharmacy council of India includes

A) Director general of health services

B) Director of central drug laboratory

C) Drug controller of India

D) All of these
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Question 87 of 100
The mesh size of USP disintegration apparatus is

A) 2 mesh

B) 5 mesh

C) 10 mesh

D) 20 mesh

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Question 88 of 100
Non curable disease comes under

A) Schedule- P1

B) Schedule- J

C) Schedule- N

D) Schedule- S

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Question 89 of 100
For which of the following BCS, in-vitro in-vivo correlation is not needed?

A) Low solubility, low permeability

B) High solubility, high permeability

C) High solubility, low permeability

D) Low solubility, high permeability

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Question 90 of 100
In competitive inhibition of enzymatic reaction, following vent occurs

A) Km increases, Vmax decreases

B) Km unchanged, Vmax increase

C) Km increases, Vmax unchanged

D) Km decreases, Vmax increases

Question 91 of 100
Isapgol shows color change when treated with ruthenium red
 A) Voilet

B) Yellow

C) Brown

D) Pink

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Question 92 of 100
The unit of measurement for conductance id

A) Ohms

B) Amperes

C) Mhos

D) Milli Volt

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Question 93 of 100
Compitative nondepolarizing neuromuscular blocking agent is

A) None of Above

B) Parathion

C) Succinylcholine

D) Trimethaphan

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Question 94 of 100
dipyridodiazepine heterocyclic ring system is present in the following drug

A) efavirenz

B) didanosine

C) nevirapine

D) amithopterine

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Question 95 of 100
Column coupling (Switching)HPLC is known as ……

A) Column back flushing

 B) Boxcar

C) Filtration

D) none of these

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Question 96 of 100
Exonucleases functions

A) to remove nucleic acid only from the end of chain

B) to remove sugar part of DNA

C) to break bond within the DNA chain

D) all of theses

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Question 97 of 100
At critical temperature, the surface tension of liquid

A) increases up to some extend

B) does not change

C) becomes zero

D) becomes negative

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Question 98 of 100
Psychrometric chart is related to

Osmotic pressure
A)

B) solubility

C) Humidity

D) evaporation

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Question 99 of 100
In ocular drug delivery system, drug absorption occurs through:

A) Cornea

B) Sclera

C) Conjunctiva

D) All of the above

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Question 100 of 100

Which type of sample is used in gas chromatography?

A) Liquid or gas

B) Solution

C) Solid, liquid or gas

D) Crystal
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