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. GRAND TEST
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a) 4-Aminobenzoic acid & 2-hydroxytriethyl amine b) Sodium p-aminobenzoate & 2-
chlorotriethyl amine
c) 2-Chloroethyl ester of 4-aminobenzoic acid & diethyl amine d) All of these
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Q.3 UV spectroscopy is the type of
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a) Emission spectroscopy b) Absorption spectroscopy c) Vibrational spectroscopy d) None of
these
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a) CNS b) Autonomic ganglia c) Liver d) CVS
flexuosus
Q.10 Which one of the following antibodies contributes in immune response through
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cytolytic action?
a) IgG, IgE b) IgG, IgM c) IgA, IgM d) IgA, IgD
Q.11 When partial agonist is administered along with agonist. The effect of agonist may be
a) Potentiated b) Suppressed c) Unchanged d) Depends on the type and nature of receptor
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Q.12 2-bromopyridine + Benzyl cyanide + 2-(dimethyl amino) ethyl chloride gives
a) Mepyramine b) Triprolidine c) Pheniramine d) Bromopheniramine
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Q.14 List of minimum equipments required for efficient running of pharmacy is given in
schedule
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a) M b) A c) N d) R
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Q.15 The proteolytic enzyme obtained from plant origin is
a) Pepsin b) Diastase c) Papain d) Renin
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Q.16 Cantharidin, used as counter-irritant is obtained from
a) Stem wood of santalaceae family b) Roots of piperaceae
c) Insets of meloidae family d) Aerial part of chenopodiaceae family
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Q.17 All of the following are antimetabolite except
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a) Methotrexate b) Thioguanine c) Procarbazene d) Cytarabine
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Q.18 Which one of the following drug is likely redistributed in human body?
a) Drug with high aqueous solubility b) Drug with very low aqueous solubility
c) Intermediate aqueous solubility d) Drug with very low lipid solubility
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Q.21 All of the following are biogenetically derived from tyrosine except
a) Colchicine b) Morphine c) Codein d) None of these
Q.22 Phenobarbitone is a
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Q.25 Sta-Rx-1500 is used in tablet formulation as
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a) Diluent b) Disintergrant c) Binder d) Glidant
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Q.26 The reference standard used in ESR is
a) Trimethylsilane b) Diphenyl picryl hydrazyl c) Methyl silane d) Tstramethylsilane
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Q.27 Stomatal index is used as analytical constant for identification and authentification of
a) Baark drug b) Volatile oil c) Leaf drug d) Fixed oil
Q.28“Tachyphylaxis” is related to
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a) Development of tolerance due to repeated use of drug b) Development of tolerance to
pharmacological related drug
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c) Rapid development of tolerance d) Resistance of microorganism to inhibitory action of
antimicrobials
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council
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Q.34 Dibenzthiazepine derivative is
a) Olanzapine b) Clozapine c) Quetiapine d) Loxapine
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Q.35 Which one of the following adverse effect of the drugs is very common among persons
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having similar genetic make-up?
a) Intolerance b) Photosensitivity c) Idiosyncrasy d) Mutagenicity
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Q.36 Over use of which of the following drug may cause parkinsonism?
a) Levodopa b) Domperidone c) Imipramine d) Chlorpromazine
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Q.37 The main active constituent present the eucalyptus oil is
a) Alpha-pinene b) Limonene c) 1:8 Cineole d) Menthol
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Q.38 The number of NMR signal expected for CH3-CH2-Cl is
a) 3 b) 5 c) 2 d) 4
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Q.41 Remoxipride is a
a) Benzamide b) β-aminoketone c) Fluorobutyrophenone d) Dibenzoxazepine
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a) Scattered light b) Absorbed light c) Transmitted light d) None of these
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Q.45 Which one of the following drug is used for treatment of myasthenia gravis?
a) Physostigmine b) Pilocarpine c) Edrophonium d) Pyridostigmine
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Q.46 Emulsifier is added in emulsion to prevent
a) Phase inversion b) Creaming c) Coalescence d) All of these
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Q.47 Which one of the following drug belonging from diphenylbutylpiperidine class?
a) Penfluridol b) Haloperidol c) Resperidone d) Sulpieride
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Q.48 The principle of separation in paper chromatography is mainly
a) Adsorption b) Fractionation c) Partition d) Selective adsorption
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Q.49 The presence of candelabra trichomes is microscopic feature of the drug listed a to d.
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Q.50 Which one of the drug acts directly to alter fungal cell membrane permeability?
a) Ampicillin b) Polymixin B c) Amphotericin B d) Streptomycin
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c) Phenoxybenzamine – Alpha receptors
d) Pindolol - Beta receptors
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Q.56 The standard potential of a hydrogen electrode is
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a) 0 b) 1 c) 100 d) 7
Q.57 Which one of the following drug is less effective in patient suffering from liver
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disease?
a) Drug having higher presystemic metabolism b) Prodrug
c) Acidic drug d) Basic drug m
Q.58 Metabolism of carbamazepine is proceeds mainly through
a) Acetylation b) Epoxide formation c) Sulfide formation d) Sulfoxide formation
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Q.59 Saturated picric acid solution in cold water used for the detection of alkaloid is known
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as
a) Hager reagent b) Mayer’s reagent c) Dragendorff’ss reagent d) Wagner’s reagent
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Q.63 Shellac is a resin obtained from an inset laccifera iacca, and it is used as a
a) Colouring matter b) Coating material c) Anthelmintics d) Base of ointment
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Q.66 A drug represents SSRIs and 5HT2A antagonist is
a) Citalopram b) Maprotiline c) Trazodone d) Amoxapine
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Q.67 Rate constant of zero-order kinetics is expressed as (C0= Initial concentration of drug
in plasma, Ct = concentration of drug in plasma at
time t )
a) Ct – C0 / t b) (Co – Ct ) t c) (Co – Ct ) / t d) None of these
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Q.68 Which one of the following drug included in “dope test” for athletes?
a) Propranolol b) Prazosin c) Dexamphetamine d) Diazepam
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Q.69 Which one of the following parameter is important for passive diffusion of drugs from
gastrointestinal tract?
a) Permeability coefficient b) Dissolution constant c) pH of absorption site d) Dissociation
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constant
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a) Limit test for chloride b) Limit test for sulfate c) Microbial limits d) Sterility test
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Q.75 Some of the antihistaminic are also effective in parkinsonism because of their
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a) Sedative property b) Dopaminergic activity c) Anticholinergic activity d) All of these
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Q.76 General structural formula of oximes is
a) R-N=CH-OH b) R-NH-OH c) R-N=O d) R-CH=N-OH
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Q.77 Dog senna an adulterant of senna which is obtained from
a) Cassia auriculata b) Cassia obovata c) Cassia fistula d) Cassia cinnamon
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Q.78 An important reaction for the synthesis of amino acid from carbohydrate
intermediate is transamination which requires the co-factor
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a) Thiamine b) Riboflavin c) Niacin d) Pyridoxal phosphate
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Q.79 Solutions of two different solids are said to isotonic if they have almost similar
a) Surface tension b) Viscosity c) Concentration d) Osmotic pressure
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c) Noyes-Whitney equation
d) Handerson-Hasselbatch equation
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Q.86 Nernst equation is used to measure
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a) Absorbance b) Turbidity c) Electrode potential d) Diffusion current
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Q.87 In chromatographic analysis Rf value range from
a) 1 – 100 b) 0 – 1 c) -1 – +1 d) 0 – 10
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Q.88 Anthraquinone of cascara contain mainly
a) C-glucosides b) N-glucosides c) O-glucosides d) S-glucosides
Q.89 Diphenhydramine is a
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a) An amide b) Amino alkyl ether c) Amino alkyl ester d) An aldehyde
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Q.90 The members of the DTAB hold the office for
a) 5 yrs b) 3 yrs c) 7 yrs d) 1 yrs
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Q.92 Which one of the following organ has greatest capacity to biotransform the drugs?
a) Kidney b) Skin c) Liver d) Heart
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Q.95 Most major metabolic pathways are considered mainly either anabolic or catabolic.
Which of the following pathway is most correctly
considered to be amphibolic?
a) Glycolysis b) Citric acid cycle c) Gluconeogenesis d) Lipolysis
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Q.96 Which of the following oil is used as non-aqueous vehicle for intramuscular injection?
a) Castor oil b) Sesame oil c) Linseed oil d) Mustard oil
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Q.97 At the end point in the potentiometric titration the
a) Potential is maximum b) Change in potential in minimum
c) Potential is minimum d) Change in potential in maximum
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Q.98 Creams are
a) Ointment b) Gels c) Elixir d) Emulsion m
Q.99 Aspirin is preferably prepared by which method of tablet manufacturing?
a) Direct compression b) Wet granulation c) Dry granulation d) Direct compression & dry
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granulation
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ANSWERS
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1 2 3 4 5 6 7 8 9 10
a d b c c a c d b b
11 12 13 14 15 16 17 18 19 20
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b c d c c c c b a a
21 22 23 24 25 26 27 28 29 30
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d b d c a b c c b a
31 32 33 34 35 36 37 38 39 40
a d b c c d c c c c
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41 42 43 44 45 46 47 48 49 50
a b a a d c a c d c
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51 52 53 54 55 56 57 58 59 60
b c d b c a b b a a
61 62 63 64 65 66 67 68 69 70
c c b a c c c c a c
71 72 73 74 75 76 77 78 79 80
c a c c c d b d d b
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81 82 83 84 85 86 87 88 89 90
d b c c b c b a b b
91 92 93 94 95 96 97 98 99 100
d c d a b b d d c a
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.b
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