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Composition
Each 1 ml contains:
Magnesium sulfate 7 H2O 100 mg
Indications
Convulsions associated with pre-eclampsia and eclampsia of pregnancy and to control convulsions associated with acute
nephritis in children. Hypomagnesaemia especially acute cases accompanied by signs of tetany.
MAGNESIUM SULFATE is indicated in uterine tetany and premature labour as a myometrial relaxant.
Paediatric Dose:
Anticonvulsant:
I.M.:
10 - 40 mg/kg as needed to control convulsions.
Precautions
Pregnancy:
MAGNESIUM SULFATE is parenterally administered in the treatment of toxaemias of pregnancy. It may produce
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hypotonia, hypotension and respiratory depression of the neonate, therefore it is usually not administered to the mother
during the 2 hours preceding delivery unless it is the only therapy available.
Breast-feeding:
Problems in humans have not been documented.
Drug Interactions
Concurrent use with calcium salts may neutralize effects of MAGNESIUM SULFATE.
Parenteral MAGNESIUM SULFATE in digitalized patients may cause cardiac conduction defects.
MAGNESIUM SULFATE potentiates the action of neuromuscular blockade.
MAGNESIUM SULFATE may potentiate the action of C.N.S. depressants.
Contra_indications
Heart block, renal failure (Creatinine clearances < 20 ml/min.) and intolerance to MAGNESIUM SULFATE.
Side effects
Parenteral MAGNESIUM SULFATE injection may cause flushing, hypotension, hypothermia, hypotonia, reduced heart
rate and reduced respiratory rate.
Presentation
Box of 5 or 50 ampoules of 10 ml each.
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