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HOLOGENIX – CELLIANT® TECHNOLOGY

•  Hologenix has spent over a decade developing and


perfecting our technology into a commercially viable
process with significant and substantial health benefits.

•  Celliant is protected by seven patents worldwide.

•  Celliant is proven by five clinical studies.

•  Hologenix works with well respected and established


brands including Reebok, adidas Golf, Saucony and
Ironman.

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PERFORMANCE APPAREL MARKET

Performance apparel is an expanding market1.


•  Over 100 Million Americans exercise on a regular basis.

•  As of 2008 the performance apparel industry was a $6.4 billion industry.

•  Expected to grow 19% to $7.6 billion by 2014.

•  Biggest area of growth is technical fabrics.

(in billions)

1. Data obtained from Thomson Reuters Corporation R


HEALTH & WELLNESS INDUSTRY

•  The Health & Wellness Industry has increased in sales from


$59 billion in 2003 to over $112 billion in 20081.

•  Declining health and increased availability is driving people to


these products.
•  The economic downturn is causing people to be more
discerning, only purchasing proven products.

•  The market is continuing to grow.

1. Data obtained from Natural Marketing Institute R


HISTORY OF TECHNICAL FABRICS

•  Gore-Tex (1978) – First waterproof/breathable fabric. Works by allowing water


vapors to exit through tiny holes that are too small for water droplets to get back in.

•  Compression (1983) – Decreases muscle vibrations to reduce fatigue.

•  Coolmax (1986) – Wicking capabilities and better breathability than natural fibers.

•  Antimicrobial (2004) – Technique from early 20th century is now becoming popular
in consumer products. Uses Trevira Bioactive (silver ions attach to bacteria to
destroy them).

None of these performance fibers are responsive textiles.

Responsive textiles are textiles that interact with the environment.

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CELLIANT - THE WORLD’S FIRST RESPONSIVE TEXTILE

Celliant is a revolutionary technology that harnesses the body’s


natural energy through the use of minerals and fibers. The
result is enhanced tissue oxygen levels which helps reduce pain,
improves circulation, aids in muscle recovery and helps to
balance body temperature.
! Polyester based; can be integrated into any textile
! Versatile for a wide range of products
! Efficacy proven through five clinical studies

Hologenix, the maker of Celliant fiber is the only company to have


performed U.S. based clinical studies proving the efficacy of its product.

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THE PROVEN EFFECTS OF CELLIANT

In clinical testing, Celliant has been proven to reduce pain,


increase blood circulation, increase oxygen levels, help balance
body temperature and improve quality of sleep.
! Clinically proven to increase blood circulation and oxygen levels in the body, 2003.
! Clinically proven to increase oxygen and help balance body temperature, 2005.
! Clinically proven to reduce pain, 2008; published Spring, 2009.
! Clinically proven to increase oxygen, 2009.
! Initial clinical testing indicates improved sleep quality and a reduction in nocturnal
awakenings, 2009-2010.

Hologenix, the maker of Celliant fiber is the only company to


have performed peer-reviewed, published, clinical studies proving
the efficacy of its product.
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2003 – OXYGEN INCREASE IN DIABETIC SUBJECTS

•  Performed by Lawrence A. Lavery, DPM, MPH, an associate professor in the


department of orthopedic surgery and rehabilitation at Loyola University Medical
Center and Hines Veterans Administration Hospital in Chicago.
•  Tested TCPO2 (how much oxygen reaches the surface of the skin) in the hands
and feet.
•  Study of 20 diabetic subjects wearing Celliant gloves and stockings vs. placebo
garments.
•  Within one hour subjects showed on average a 13.6% improvement in their hands
with 100% Celliant gloves and an 8% improvement in their feet with 50%
Celliant stockings.

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2005 – OXYGEN INCREASE IN HEALTHY SUBJECTS

•  Performed by Graham M. McClue, Ph. D., a researcher with Hyperbaric Treatment


& Training Services Ltd., an independent research facility in Houston, Texas.
•  Tested TCPO2 in the hands and feet.
•  Double blind study of 13 healthy subjects wearing Celliant® gloves and stockings
vs. placebo garments.
•  Within one hour subjects showed an increase of oxygen levels by 10% to 24%.

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2008 - DIABETIC PAIN STUDY
•  Performed by Dr. Ian Gordon, M.D., Ph.D. at University of California Irvine Medical Center,
Director of the University of California Wound Clinic, Associate Clinical Professor of
Surgery at the University of California, Irvine and Chief of the Vascular Surgery Section at
the VA Long Beach Healthcare System.
•  Single-center, prospective, double-blind, randomized trial approved by the institutional
review board with test subject receiving either Celliant or control socks.
•  55 Subjects filled out McGill Short Form Pain Surveys—an industry accepted scale for
measuring pain relief that is used in FDA trials for pain relief medications—for two consecutive
weeks to measure pain.
•  Participants received a 2.7x greater reduction in pain for participants wearing products enhanced
with Celliant versus those wearing placebo products.

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2009 – OXYGENATION STUDY

•  Ian Gordon, M.D., Ph.D. F.A.C.S., Clinical Professor of Surgery, UC Irvine.


•  24 healthy volunteers wore both Celliant and placebo garments for 90 minutes.
•  Subjects were tested for skin temperature, grip strength and TCPO2 levels.
•  Overall 8% increase in oxygen levels and 12% increase in grip strength.
TCPO2

(Minutes)
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2009-10 CELLIANT SLEEP STUDY

Sleep efficiency with a placebo


! Significant nocturnal awakenings
! 67% Sleep efficiency

Sleep efficiency with Celliant


• Zero nocturnal awakenings
• 95% Sleep efficiency

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FUTURE OF CELLIANT STUDIES

! Science Advisory Board

! Wrist & Elbow Strength Study

! Cycling Performance Study

! Wound Healing Study

! Sleep Quality Study

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TCPO2 TESTING

•  Transcutaneous Oxygen Pressure (TCPO2) is


the measurement of how much oxygen is
reaching your muscles.
•  Developed for diabetics to check for hypoxia
(oxygen deficiency).

•  The patient sits comfortably while the technician applies the sensory nodes to the skin.

•  Test takes about 3.5 hours.


•  90 minutes with placebo.
•  30 minute cool down.
•  90 minutes with Celliant.
•  Testing with both the placebo and
Celliant allows each patient to serve as
their own control.

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WHAT TYPES OF RENEWABLE ENERGY ARE
AVAILABLE?

Water?
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WHAT TYPES OF RENEWABLE ENERGY ARE
AVAILABLE?

Wind?
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WHAT TYPES OF RENEWABLE ENERGY ARE
AVAILABLE?

Solar?
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WHAT ABOUT THE BODY? - SCIENCE OF LIGHT

With almost 7 billion people on Earth, the most


abundant energy source is the human body.
! Thermographic cameras show infrared emissions.
!  Certain minerals are photocatalysts which means that
they are “optically responsive” absorbing light at the
surface, redirecting it, and sending it back to the body.
! These minerals can be infused into fibers.

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ELECTROMAGNETIC SPECTRUM

The human body emits photons ranging from 200-850nm1 which includes light in
the ultraviolet, visible and infrared wavelengths.
In order to be visible to the human eye without additional equipment there would
need to be between 100 and 1,000,000 more photons per square centimeter.
1. http://www.photobiology.com/photobiology99/contrib/applegate/index.htm
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EXAMPLES OF LIGHT RAYS

X-Rays (.01 to 10nm wavelengths) are high energy light beams


that pass through the body. Because bones are made of larger
atoms than soft tissue, we are able to record their absorption with
an x-ray camera.

Microwaves (1mm to 1m wavelengths) are not just used to cook


food. They are actually much more useful in communication
where they transmit information for long distance telephone,
internet, radar and GPS.

Radio waves (1m to 100m wavelengths) send analog sounds at


set frequencies. They are also used in medicine and astronomy.

What is the connection? All forms pass through solid objects while remaining effective.

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SCIENCE OF LIGHT - EARLY HISTORY

Light therapy or photobiology has been used for centuries


•  Light therapy dates back to early civilization when the Ancient Greeks first
recognized that exposure to sun light could have health benefits.

Solar energy is any radiant light or heat energy emitted by the sun
"

•  Energy from the sun is proven to be beneficial.


•  It is the bodies main source of Vitamin D which plays an essential role in many
major organ systems.
•  Increases the flow of calcium into the bloodstream.

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SCIENCE OF LIGHT - 20TH CENTURY USE

Nobel Prize
!  Niels Finsen won the Nobel Prize for Medicine in 1903 for
his studies on using light therapy to treat tuberculosis and
small pox.

Other forms of light are also proven to benefit the body.


"

"! Infants with neonatal jaundice have been prescribed treatments of blue
light since the 1930s.
! In the 1960’s red light was proven to increase production of new
collagen which makes healthier looking skin. Red light pens are now
commonly sold as an anti-wrinkle therapy.
*Both of these processes are FDA approved.
"! In 1999 NASA proved that light can be used to stimulate cell growth and
speed wound healing.

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CELLIANT MINERALS

•  Although the formula for Celliant is a trade secret, the


following three minerals are used in our technology:

Titanium Dioxide – Absorbs available energy.

Silicon Dioxide (Silica) – Acts as a reflector of


energy and as an anti-microbial.

Aluminum Oxide (Alumina) – Enhances


strength of reflectivity.

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FROM MINERALS TO FIBER

•  These minerals are ground down to into a


powder finer than one micron.

•  This powder is added to a liquid polyester


resin which creates chips called Celliant
Master Batch.

•  The Celliant Master Batch is extruded into


staple fiber (right) which is baled and sent to
a spinning facility where it is made into yarn.
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CELLIANT PROPERTIES

! Specially formulated, worldwide patent-protected, mineral compound.

! Micron-sized particles infused into fiber during extrusion.

! A permanent part of the fiber, lasting the life cycle of the material.

2,000x magnification of a cross section of Transmitted light image of Celliant Fiber in plane polarized
Celliant Fibers light (n=1.544)

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HOW DOES CELLIANT WORK?

1. Celliant fibers are created from 2. Celliant fibers absorb energy 3. Celliant converts the energy into
natural minerals and embedded into from the body. a usable form.
polyester fibers.

4. Celliant recycles this energy 5. This recycled energy triggers 6. These reactions result in increased
back to the body. natural chemical reactions in the blood flow and oxygenation to the
body. tissue.

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“COMPETITOR” - FAR-INFRARED FABRICS

Current far-infrared materials in the marketplace:


Sample Claims:
Super Textile
• Improves blood circulation
and 18.9% increase
Shinin Silica Corp.
• Thermal skin temperature
increasing: +0.77
Shang Yung Co.
• Moisture transferring and
quick-drying
Kodenshi
• Antibacterial and
deodorization
Revoreno
• Increases body energy -44
to 99%
Nexus One

These companies have not provided any independent clinical testing.


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CONSUMER BENEFITS

Performance: Celliant provides additional oxygen to the muscles allowing more


efficient energy production.
! Enhances performance.
! Less muscle fatigue during activity.
! Increased stamina and strength.

Recovery: Celliant speeds the natural healing process reducing soreness and
muscle fatigue from exercise.
! Increased blood circulation stimulates healing process.
! Speeds recovery time.
! Allows for more active lifestyle.

Wellness: Celliant causes better blood circulation and body temperature


regulation.
! Reduces pain.
! Improves quality of sleep.
! Increases overall comfort.

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WHAT RESEARCHERS ARE SAYING ABOUT
CELLIANT
“It’s important to note that properly controlled clinical trials have shown a positive effect from wearing clothing enhanced with
Celliant®. Frankly, as a skeptic, I was surprised at the results and am excited to conduct additional trials.”
! Dr. Ian Gordon, MD, PhD
Director of the University of California Wound Clinic, Associate Clinical Professor of Surgery at the University of California,
Irvine and Chief of the Vascular Surgery Section at the VA Long Beach Healthcare System

“This study shows a significant increase in blood flow in the skin. This improvement might be enough to take patients from being
symptomatic to asymptomatic, which for patients that are taking 10 or 15 drugs, to be able to wear a garment with no negative side
effects is a tremendous advantage.”
! Dr. Lawrence A. Lavery, DPM, MPH
Associate Professor, Department of Orthopedic Surgery and Rehabilitation, Loyola
University Medical Center & Hines Veterans Administration Hospital, Chicago, Illinois

“There are a number of benefits that will come out of wearing this product. In the athlete, it will increase oxygen metabolism rates,
therefore enhancing performance. It will also aid recovery of people that don’t exercise very often. Most often you exercise and become stiff.
This will help to eliminate the stiffness. In the diabetic population, it will increase oxygen at the surface or oxygen to wounds and
eventually the wounds will heel on a quicker basis.”
! Dr. Graham McClue, PhD
Research Director, Hyperbaric Treatment & Training Center, Houston, Texas

“The first two participants reported a subjective improvement of their sleep with the use of the active
garment mattress cover… In addition, objective sleep recordings in both subjects showed improved
sleep efficiency (more sleep while in bed), a decreased wake after sleep onset time (less total night time
awake after initial sleep onset), and an overall reduced number of nocturnal awakenings”
! Dr. Marcel Hungs, MD, PhD
Assistant Clinical Professor, Department of Neurology, University of California, Irvine
Director, Center for Sleep Medicine R
WHAT CONSUMERS ARE SAYING ABOUT
CELLIANT
"I was having a lot of sleeping problems due to breaking my back in a motocross accident about 5 years ago. A friend suggested I try a
mattress pad with Celliant®. Ever since, I almost sleep too well. I am a firm believer in this product and recommend it to everyone!"
! Donny Emler Jr. aka “LIL D”, FMF Racing

“I have been a type II diabetic for 15 years and recently neuropathy has been affecting my legs and feet. I tried a number of different
support hose and have not been satisfied with their performance. In many cases they restricted the blood flow and ended up increasing
the pain. Your socks have been fantastic. I seem to get the support that I need without the restrictions. They not only help with the
numbness but provide the support that I need to assist me in walking."
! Frank S. Chase, Nashua, New Hampshire

“ During the 2005 Toronto Marathon, I wore Celliant® running socks and had zero problems with my feet... As it happened, I ended up
seeing my doctor a few days later for my annual physical. He was amazed that my feet didn't show any signs of blistering, swelling,
bruising etc.”
! Andrew Wells, Real Estate Broker and Marathon Runner, Toronto, Canada

“In "Terminator 3: Rise of the Machines," I play the most powerful machine yet, opposite Arnold Schwarzenegger. Powerful machines
may be impervious to pain, but people aren't, so I wore Celliant® socks throughout a difficult and grueling shooting schedule, and it
helped me recover quickly from exertion.”
! Kristanna Loken, Actress

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CELLIANT® PARTNERS

BEDDING HOSIERY
• Ambient • Achieve O2
• Deslee Clama • Arriva
• Fabrictech • Reflexa Socks
• Ironman • Wickers
• Serta

PERFORMANCE APPAREL OTHER


• Courage Sports • Belevation
• Reebok ZigTech Apparel • Draper Therapies
• Saucony AmpPro2 • Pedors Shoes
• TaylorMade-adidas Golf • Grasshopper Shoes
• Equipedic

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CELLIANT®

•  Safe

•  Proven

•  Revolutionary

David Horinek
Hologenix, LLC
(888) 721-1545
david.horkinek@celliant.com
www.celliant.com R

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