Tablet single punch

machine
Rebin sulaiman Abdullah
 Single punch tablet press is also called as a eccentric press or single station
press
 It is most simplest machine for tablet manufacturing.
 Single station tablet press employs a single tooling station that is a die and a
pair of upper and lower punches.
 This tablet press is available as both manually operated and power driven.
 In this single punch tablet press, the compaction force on the fill material is
exerted by only the upper punch while the lower punch is immovable such as
action equivalent to hammering motion.
 TPM is approximately 60
The tablet press compartments
Feed mechanism
 The mechanism involved in tablet press is that compaction of powder blend is
accomplished by exerting the presser via upper to word lower punches.

 The resultant tablet are formed in the die cavity with their shape and size.

 It involved compression of only upper punch.

Working

 The process of tablet compression can be divided into three stages

 1-filling
 2-compression
 3-ejection
Filling

 The lower punch falls with in the die leaving a cavity into
which a particulate matter flows under the influence a
gravity from a hopper. Through tablets are
usually described in terms of weight. The die is filled
by volumetric process
Compression

 The upper punch, descends ,and its tip enter the die, confining the distance
separating the punch force decreases, either by movement of upper punch
alone.
 The porosity of the contents of the dies progressively reduced, and the
particles are forced into the over closer proximity to each other.
Ejection

 The upper punch is withdrawn from the die and show the force being applied
to the tablet is removed.

 The effect of this might to be cause the deformed particles to return to their
former shape, which would result in a decrease inter-particulate contact and
hence tablet strength.
Advantage

 The machine structure is rational and small.

 it s very to operate, and it operates at a high utilization ratio.
 The machine capable of utilize a high amount of pressure to reduce the
weight difference between the tablets while maintaining a low noise level.
 The machine also provides a continuous control over the loading of the raw
materials, and the thickness of tablet.
Experiment

 AIM:- To prepare and compress 30 tablets each contains 0.9 g sodium chloride
by direct compression method.
 Rx Sodium chloride 0.9 g
 Equipment’s required:- Weighing balance, sieve, tablet punching machine.
 The crystals of sodium chloride are granular and free Flow able (No need for
granulation)
 Sodium chloride crystals when compressed, bind together, To produce tablets
of good hardness (no need for binding Agent)
 Tablets of sodium chloride, being soluble tablets (no need for disintegrating
agent)
 Sodium chloride when compressed, dose not stick to metal of punches and
dies of tablets machine (no need for lubricant).
Procedure:

 1-Screen sodium chloride crystals through a No. 16-22 sieve. This step is
necessary to break down lumps and to produce a uniform granular powder.
 2- Adjust the tablet machine to 1/2 gm size tablet.
 3- Fill the sodium chloride into the feeder (hopper) of tablet machine whose
dosing unit has been adjusted for compressing tablets having weight 0.5 gm.
 4-Check on the weight of the tablets every now and then adjust the machine
accordingly.