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Abstract
para-Menthane-3,8-diol(PMD) is a monoterpene
spent product of the distillation of leaves of the
Australian lemon-scented gum tree (updated
nomenclature Corymbia citriodora ssp.
citriodora). In April 2005, the U.S. Centers for
Disease Control and Prevention (CDC) endorsed
two non-deet mosquito repellents, including
PMD. However, few mosquito professionals have
in-depth familiarity with the history and efficacy
of PMD. In this article, we describe the origin and
development of PMD as a repellent and offer a
comprehensive review of its performance against
Aedes, Anopheles, Culex, and Ochlerotatus. In
addition, we present original data from field and
laboratory studies involving large numbers of
subjects and comparisons with high-
concentration deet and other repellents. We
conclude that not only is the CDC endorsement
warranted but also that it probably
underestimates the value of PMD as a deet
alternative for public health applications.
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Publication types
Research Support, Non-U.S. Gov't
MeSH terms
Aedes
Animals
Anopheles
Culex
Culicidae*
Cyclohexane Monoterpenes
DEET
Female
Humans
Insect Repellents*
Male
Menthol / analogs & derivatives*
Ochlerotatus
Substances
Cyclohexane Monoterpenes
Insect Repellents
DEET
Menthol
terpin
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