Documenti di Didattica
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Dose
ordered Action & Absorption Metabolism/ Adverse Reaction Nursing
Generic/Trade Route,
Names freq. Classification Reason Distribution Excretion Side effects Considerations
Routine
Advair discuss anti-asthmatic Asthma A:30% M:liver sysphonia; hoar- 1 min. between
fluticasone & corticosteroid D:10-25% E:<5% urine seness; fungal inhalations
salmeterol airway and feces infection 1st broncho dilat.
check f/excoriat.
Decongestant arterioles in & bleeding; puls
Afrin sympathomim. nasal pass. BP. Not w/ HTN
constrict DM,HD,thyroid pr
selective beta2-
Albuterol adrenergic asthma/ A:PO well M:liver + heart rate up check lungs, HR,
Proventil bronchodilator COPD D:lact. E: BP. Stop meds w
wheezing
diuretic (weak) cause loss of A:>90% M:liver hyperkalemia BP down -fall rsk
Aldactone K-sparing Na, HCO3,Ca D:plac. Lact. don't give suppl urinal empty
spironalactone saves K+,H+ potasium I&O,call light
not for renal pt
Aleve 837 analgesic,NSAID pain,fever A:complete M:liver GI bleed; full glass of H2O
Naproxen antipyretic inflammation D:plac. Lact. E: hepatitis;S&J syn upright for 30min
anaphylaxis drowsy;noETOH
Altace pg 147 antihypertensiv mng HTN A:50-60% M:liver cough, hypoTN check BP
ramipril ACE inhibitor mng CHF D:? E:60%kidn. angioedema
check HR, BP migraine HA 40% fecal agranulocyt. taste desturb.
proteinurea
anti anxiety anxiety, A:well M:compl.liver drowsy, dry mth shake suspens
Atarax anti histamine preop. Sedat D: unknown E:bile feces pain at IM site deep IM Ztrack
hydroxyzine sedative/hypnot anti emetic Painful-don't use
anti pruritic deltoid
Avodart BPH (benign reduces size A:60% M:liver reduced libido wear gloves
dutasteride prostate Hyperp prostate D:11.5% into E:feces ejac. Disorder no blood donate
use gloves agent semen impotence
Benicar 153 anti hypertensiv A:26% absorb M: renal failure CI renal disease
olmesartan angiot. II antag. lowers BP D:? E:kid 30-50% hyperkalemia
BP check reduce stroke rest bile/feces
risk
Carbidopa/levod. anti parkinson up dopam. A: well M:GI tract & toxidity: muscle check vs w dose
dopamine agent levels in D:BBB liver twitching,winking adjustement,
corpus stratium beh.change, liver & kidn func
tongue protrude food after med.
Carboxymethyl Articial tears Treats and prevents A: cornea Chnges in vision or allergic rxn Changes in
cellulose opth tears irritation caused by epithelium vision
dry eyes.
Pain in eye
check labs,PSA
a-neoplastic A:well M:liver weakness, Naus. up BUN &
Casodex reduce risk D:? E: const., diarrhea creatan.
spread of CA
Anti -HTN analgesia A:GI tr, skin M:liver drowsy, check pulse &BP
Catapres adrenergic hypertension D:CNS,plac. E:50% unch dry moutn last dose @HS
Clonidine opioid withdr in urine gradual d/c
antipsychotic reduce poss. A: well M:1st pass Hyperglycemia give prune juice
Clozaril 300 dopamine & and neg. sx D: rapid bbb liver weight gain, sedation, watch
clozapine serotonin block of schizophr. & placenta E: orth. hypoTN for EPS (not
red. Suicide agranulocytosis common)
Clindamycin Anti-biotic Treats skin, A: Well M and E: liver Dizziness, headache, vertigo, Monitor bowel
(Cleocin) Inhibits protein respiratory, Gyn, D: Widely arrhythmias, hypotension, elimination, abd
synthesis of Osteo, abdominal diarrhea, N/V, rash, phlebitis , cramping, assess
bacteria infections and colitis for infction
septicemia
Codeine #2=15mg opioid analgesic pain,cough A:50%PO M:liver conv. confusion,sedat. CNS depressant
narcotic #3=30mg allergy,cold mnge diarrh 100% IM to morphine hypoTN,constip. caut:MAO inhib.
hold resp.<10 #4=60mg cough remedy D:wide,plac,lac E:10% kidney N&V, admin before severe pain
urinary retention dependence
Cogentin pg192 cholinergic suppress A: well M: unknown dry mouth red dose w/musc
benztropine blocker in tremors D: unknown E: unknown constipation weakness, not w
Mesylate corpus statium sedation/up HR narr. Angl glauc.
Laxative, stool
softener constipation A:small intes. M: throat irritation w full glass water
D:? E:bile mild cramps no up peristalsis
Colace
docusate sodium
anti emetics mng N&V A:variable M:liver GI Neuroleptic mal. gloves, w/food;
Compazine anti psychotic trt psychosis D:high cons in syndr.; agranulo VS, sedation prec.
prochlorperazine phenothiazine & anxiety CNS, plac. Lac. cytosis, xtr pyram tardive dyskinesia
blur vis., const. dry mouth
antiparkinson prevent brk- A:35% rapid M:highly neurol.mal.synd. adm. w levodopa
Comtan COMT inhibitor dwn of levo D:unknown E: bile rhabdomyolysis mon. EPS/dyskin.
entacapone dopa diarrhea DC gradually
dizzy; hallucin. urine:brwn/orang
orthost. hypoTN move slow
a-hypertensive reduce HR A:well, first M:extensive bradycardia, PE, food slows abs;
Coreg B-blocker 1&2 & BP; slows pass E:feces via CHF, dizzy, weak check HR,BP,
carvedilol HTN progres D:98 %prot. B bile,< 2% fatigue, hyper- Orthostatics,
hold for HR <50 unch. In urin glyc., impotence I&O
check BP
anti-HTN hypertention A:1st pass, M:14% act. renal failure check orthostatic
Cozaar angiot.II rec. lower stroke D: E:some unch liver impairment p. edema, lungs
iosartan antagonist risk kidney hyperkalemia creatinine,BUN
lipid lowering manage high A:PO 20% M:1st pass, abd. Cramps d/c w/myopathy
Crestor agent cholesterol D:? 10% metab. constip./diarrhe or up CPK levels
Rosuvastatin E:90% feces rhabdomyolysis muscle tendern.
rash/heartburn opthalmic exam
anti arrythmia reduce seiz A:slow, GI tr M:liver Ataxia, nystagm check orthostatic
Dilantin anti convulsant activity D:CSF/fatty E:kidneys hypotension & hyperkalemia
phenytoin/ alfa adrenergic contr. arryth tissue cerebrov. spasm ass. Edema,
fosphenytoin blocker manage pain w parenteral dizzy, HA, diarrh
narrow ther. Range
inotropic (force) increase A:IV only M:liver HTN, PVC's POT DANGER IV
Dobutrex beta1 adrenerg cardiac outp. D:? E: hypokalemia check dose
dobutamine w/o up HR check VS, I&O
peripheral pulse
anti emetics NV, dizzyness A:well M:liver drowsiness assess Bowel snd
Dramamine anti histamine motion sickn D:Plac, lact E: anorexia & abd pain for
dimenhydrinate dry mouth acute abdomen
check for dehydr.
anti-infective abd. Infection A:80%PO M:liver part. seizures, HA, assess for infec
Flagyl anti-ulcer disrupts DNA D:most tissue E:urine,feces dizzy, abd.pain I&O, wt., stool
&protein synt & fluids anorexia, naus. sample for
dry mouth Giardiasis
allergy,cold a-inflammat. A:<2%,local M:liver rapid dizzy, HA, nasal rinse mouth aft.
Flonase cough remedy immune D:some swall E: bleed, abd. Pain shake bef. Use
fluticasone corticosteroid modifier loss of taste adm. 15 min
intra nasal before meds
corticosteroid Na reabsorb. A:well M:liver CHF,dizzy, HA mon: fluid retent
Florinef for orthostatic hypotents r/t D:lact. arrythmias BP; no abrubt
fludrocortisone hypotention adrenocortic. fluid vol. excess discontinuation
insufficiency
antipyretic pain, inflam A:GI tract M:liver GI bleed, hepat. give with food
Ibuprofen antirheumatic fever, D: E:1% unch constip,diarrh,HA up risk CV diseas
(motrin,advil) anti inflammat. inhibits pros- kidneys dehydrat. Skin risk dehydration
NSAID analgesic taglandin syn problems; N&V
anti parkinson up dopam. A: well M:GI tract & toxidity: muscle check vs w dose
Levodopa 713 dopamine agent levels in D:BBB liver twitching,winking adjustement,
corpus stratium beh.change, liver & kidn func
tongue protrude food after med.
Adrenergic cardiac arrest A:IV rapid M:extensive bradycardia;HTN check BP q2°
Levophed vasopressor HTN; septic D: E:small amt NV;confusion;HA and HR, ECG
norepinephrine stimul. Heart; shock;upper unch urine tremor;anxiety
bitartrate vasodilate GI hemorrha urin retntn;dysrythm
check BP coronary artery cardiac arrest
Milk of Magnesia electrolyte repl. prevent hypo A:30% M: diarrhea assess bowel func
magnesium laxative Mg;laxative D:plac, lact. E: kidneys chewed w water
hydroxide antiacid
laxative constipation M: abd. Bloating, distention,sounds
MiraLax osmotic E:feces cramp,gas,naus stool.
polyethylene glycol A:nonabsorb. diarrhea fast 3-4° pre adm.
D:? clear liquids post
MS Contin
(morphine SR opioid analges. severe pain A: 30% M: liver CNS depression give before pn
TBSR) sch II PE, MI pain D: wide disturb. Percept. becomes severe
narcotic
Morphine opioid analgesic severe pain A:better IM M:liver resp. depression check vitals sign
(Roxanol) r/t PE, MI D:wide,plac. E: hypoTN,constip. hold for ICPpt &
hold for resp<10 supp cough lact. confus/sedation excess confusion
narcotic slow GI tract numbne; Stupor dependence
Nardil pg810 anti depressant increase A: well Gitract M: liver seizures,hyper NO Tyramine food
phenelzine neurotransm. D:plac. Lact. E: tensive crisis not @HS,
drug-drug intera. not for liver prob
MAOI fatal hepatic nec check PB, I&O
Neoral 125/1.25 immune suppr. organ transp 10/60 1st pass M:liver seizures;tremor ck lab changes
cyclosporin prevent D:wide E:bile/urine HTN;NV;livertox; ck hypersensit:
rejection kidneytoxic, inf. resp.&flushing
pg 339 hirsutism K-up, Mg- down
antiHTN rapid low BP A:IV rapid com M:RBC&tissue cyanide toxidity ck: BP,HR,ECG
Nipride/Nitropress peripheral vaso D:? then liver dizzy, HA,abd.pn HCO3,PCO2,pH
nitropusside dilation nausea plas. thiocyanate
anti-anginal dilate coron A:PO,SL,Buccal M: rapid,com dizzy, HA, hypoT check q 5min x3
Nitroglycerin nitrate artery for PO less bioav. plete by liver tackycardia for chestpain if
angina pect. D:? & blood enzy sbp >90
opioid agonist mod. Severe A:well M:liver confusion, seda- no MAO inhibitor
Norco (5/325) nonopioid anal- pain D:? E: tion, hypoTN no alc. A-hista-
hydrocodone/tylenol gesic constipation mines or sedativ.
narcotic (opioid) check respir.
hold for resp<10
diuretic FVE, HTN A:IV complete M:liver,minim FVD risk VS,I&O, ass. For
Osmitrol increase D:ECF E:kidneys pulm. Edema dehydration or
mannitol osmotic pressur blurred vision fluid overload
OxyFAST, Opiod. Binds to For severe pain. A: well M: liver Confusion, sedation, dizziness, Assess pain, BP,
Oxycodone opiate receptors in Supresses withdrawl D: widely respiratory depression, low BP, HR, RR vitals,
CNS. Alters pain symptoms in opiod constipation, nausea, vomiting. bowel function
perception detox. because it causes
constipation.
gen. anesthesia anesthesia A:into fat M:liver inj. Site reaction seizures, ICP,
Pentothal barbiturate up ICP D:plac;lact; E: myocard.dysfx BP; resp. depr.
thiopental seizures bbb apnea, laryngeal arrythmias
st. epileptic. spasm, resp.dep
Pyridium 944
phenazopyridine urinary pain, M:rapid with or following
urinary tract itching,burnin A:well oral unchanged bright orange meal, don't crush,
analgesic urgency, freq. D:? Cross plac kidney urine break,chew tab.
post surge M:liver part 30 min bef. Meal
Reglan gastric stasis E:25% unch IM end of surg.
metoclopramide & NV; A:GI tract urine neuroleptic Mal. 30 min bef. Chem
chemo Vom.: D:BBB, plac, drowsi, restless, check side effect
anti-emetics esoph reflux lact. extra pyrram. Sy tardive dyskinesia
eyedrops for
Scopolamine 1299 cycloplegic irritation,photophobia not for glaucoma
isopto hyoscine cycloplegic refraction blurred vision
mydriatics mng: uveitis anticholer. Effect
CI:hypermagnes
& hypocalemia
check lab values
M:no info
Slow Mag electrolyte repl. A:PO 30% E:Kidneys
magnesium Cl laxative D:Wide, plac. diarrhea
lact.