ANGEL OF MERCY

HIGHER INSTITUTE OF NURSING, BUSINESS TECHNOLOGY & BIOMEDICAL SCIENCES

P.O BOX 3500, BONABERI-DOUALA, LITTORAL REGION CAMEROON.

TEL: (237) 674 491 104 / 695 988 949 USA Contact (001) 651-283-3546
EMAIL: angelofmercy2006@msn.com

FIRST SEMESTER EXAMS 2019/2020

Department: School of Health & Business

Program: HND & Vocational School Venue: Exam Hall C
Course Title: BIOCHEMISTRY Date: 26/02/ 2020
Course Code: BCH 119 Time: 8: 00am - 10: 00am
Instructors: Mr. Nkweti Duration: 2hours

INSTRUCTIONS TO CANDIDATES: Answer the questions in each section according to the

instructions provided for the section. You are reminded of the need of sensitivity to the English
language as a primordial essence for generating grammaticality and correct usage.

Instruction: Shade the correct option.

1. A drug which prevents uric acid synthesis by inhibiting the enzyme xanthine oxidase is

(A) Aspirin (B) Allopurinol

(C) Colchicine (D) Probenecid
2. Oxidation of which substance in the body ields the most calories

(A) Glucose (B) Glycogen

(C) Protein (D) Lipids
3. Milk is deficient of which mineral?

(A) Phosphorus (B) Sodium

(C) Iron (D) Potassium
4. All the following processes occur rapidly in the membrane lipid bilayer except
(A) Flexing of fatty acyl chains
(B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phopholipids
(D) Rotation of phospholipids around their long axes

5. Which of the following statement is correct about membrane cholesterol?

(A) The hydroxyl group is located near the center of the lipid layer

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(B) Most of the cholesterol is in the form of a cholesterol ester
(C) The steroid nucleus form forms a rigid, planar structure

6. Which one is the largest particulate of the cytoplasm?

(A) Lysosomes
(B) Mitochondria
(C) Golgi apparatus
(D) Entoplasmic reticulum

7. The most active site of protein synthesis is the

(A) Nucleus (B)Ribosome
(C) Mitochondrion (D) Cell sap

8. The absorption of intact protein from the gut in the foetal and newborn animals takes place by
(A) Pinocytosis (B) Passive diffusion
(C) Simple diffusion (D) Active transport

9. The average pH of Urine is

(A) 7.0 (B) 6.0
(C) 8.0 (D) 0.0

10. Genetic information of nuclear DNA is transmitted to the site of protein synthesis by
(A) rRNA (B) mRNA
(C) tRNA (D) Polysomes

11. The general formula of monosaccharides is

(A) CnH2nOn (B) C2nH2On
(C) CnH2O2n (D) CnH2nO2n

12. Isomers differing as a result of variations in configuration of the —OH and —H on carbon
atoms 2, 3 and 4 of glucose are known as
(A) Epimers (B) Anomers
(C) Optical isomers (D) Steroisomers

13. The number of isomers of glucose is

A) 2 (B) 4
(C) 8 (D) 16

14. The carbohydrate of the blood group substances is

(A) Sucrose (B) Fucose
(C) Arabinose (D) Maltose

15. Which of the following is a non-reducing sugar?

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(A) Isomaltose (B) Maltose
(C) Lactose (D) Trehalose

16. Mutarotation refers to change in

(A) pH (B) Optical rotation
(C) Conductance (D) Chemical properties

17. The constituent unit of inulin is

(A) Glucose (B) Fructose
(C) Mannose (D) Galactose

18. The glycosaminoglycan which does not contain uronic acid is

(A) Dermatan sulphate (C) Keratan sulphate
(B) Chondroitin sulphate (D) Heparan sulphate

19. A positive Benedict’s test is not given by

(A) Sucrose (B) Lactose
(C) Maltose (D) Glucose

20. The specific gravity of urine normally ranges from

(A) 0.900–0.999 (B) 1.003–1.030
(C) 1.000–1.001 (D) 1.101–1.120

21. Obesity increases the risk of

(A) Hypertension
(B) Diabetes mellitus
(C) Cardiovascular disease
(D) All of these

22. All proteins contain the

(A) Same 20 amino acids
(B) Different amino acids
(C) 300 Amino acids occurring in nature
(D) Only a few amino acids

23. All the following are sulphur containing amino acids found in proteins except
(A) Cysteine (B) Cystine
(C) Methionine (D) Threonine

24. The functions of plasma albumin are

(A) Osmosis (B) Transport
(C) Immunity (D) both (A )and (B)

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25. An example of α-amino acid not present in proteins but essential in mammalian metabolism is
(A) 3-Amino 3-hydroxypropanoic acid
(B) 2-Amino 3-hydroxybutanoic acid
(C) 2-Amino 4-mercaptobutanoic acid
(D) 2-Amino 3-mercaptopropanoic acid

26. An example of metalloprotein is

(A) Casein (B) Ceruloplasmin
(C) Gelatin (D) Salmine

27. After releasing O2 at the tissues, hemoglobin transports

(A) CO2 and protons to the lungs
(B) O2 to the lungs
(C) CO2 and protons to the tissue
(D) Nutrients

28. An example of chromoprotein is

(A) Hemoglobin (B) Sturine
(C) Nuclein (D) Gliadin

29. An example of phosphoprotein present in egg yolk is

(A) Ovoalbumin (B) Ovoglobulin

(C) Ovovitellin (D) Avidin

30. Both α-helix and β-pleated sheet conformation of proteins were proposed by
(A) Watson and Crick
(B) Pauling and Corey
(C) Waugh and King
(D) Y.S.Rao

31. An example of a hydroxy fatty acid is

(A) Ricinoleic acid (B) Crotonic acid
(C) Butyric acid (D) Oleic acid

32. An example of a saturated fatty acid is

(A) Palmitic acid (B) Oleic acid

(C) Linoleic acid (D) Erucic acid

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33. If the fatty acid is esterified with an alcohol of high molecular weight instead of glycerol, the
resulting compound is
(A) Lipositol (B) Plasmalogen
(C) Wax (D) Cephalin

34. A fatty acid which could be synthesized in the body and has to be supplied in the diet

(A) Palmitic acid (B) Lauric acid

(C) Linolenic acid (D) Palmitoleic acid

35. Essential fatty acid:

(A) Linoleic acid (B) Linolenic acid
(C) Arachidonic acid (D) All these

36.Vitamins are
(A) Accessory food factors
(B) Generally synthesized in the body
(C) Produced in endocrine glands
(D) Proteins in nature

37. Vitamin A or retinal is a

(A) Steroid
(B) Polyisoprenoid compound containing a cyclohexenyl ring
(C) Benzoquinone derivative
(D) 6-Hydroxychromane

38. Fat soluble vitamins are

(A) Soluble in alcohol
(B) one or more Propene units
(C) Stored in liver
(D) All these

39. Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising
(A) NADPH + (B) FAD
H+ (D) NADH +
(C) NAD H+

40. Preformed Vitamin A is supplied by

(A) Milk, fat and liver
(B) All yellow vegetables
(C) All yellow fruits
(D) Leafy green vegetables

41. A Holoenzyme is
(A) Functional unit (B) Apo enzyme
(C) Coenzyme (D) All of these

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42. Example of an extracellular enzyme is
(A) Lactate dehydrogenase
(B) Cytochrome oxidase
(C) Pancreatic lipase
(D) Hexokinase

43. When ATP forms AMP

(A) Inorganic pyrophosphate is produced
(B) Inorganic phosphorous is produced
(C) Phosphagen is produced
(D) No energy is produced

44. Alcohol dehydrogenase from the liver contains

(A) Sodium (B) Copper

(C) Zinc (D) Magnesium

45. Hormones
(A) Act as coenzyme
(B) Act as enzyme
(C) Influence synthesis of enzymes
(D) Belong to B-complex group

46. Hormone that bind to cell surface receptor and require the second messenger camp is
(A) Antidiuretic hormone
(B) Cholecystokinin
(C) Calcitriol
(D) Gastrin

47. A nucleoside consists of

(A) Nitrogenous base
(B) Purine or pyrimidine base + sugar
(C) Purine or pyrimidine base + phosphorous
(D) Purine + pyrimidine base + sugar + phosphorous

48. The most abundant free nucleotide in mammalian cell is

(A) ATP (B) NAD

(C) GTP (D) FAD

49. The total body water in various subjects is relatively constant when expressed as percentage of
the lean body mass and is about
(A). 30% (B) 40%
(C) 50% (D) 70%

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50. The percentage of water contained in the body of an individual is less because

(A) High fat content (B) Low fat content

(C) High protein content
(D) Low protein content

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SECTION-B (STRUCTURAL) (10marks)

Write short notes on the following

1. Name all the fat soluble vitamins and give two functions each.
2. Give 3 functions of hormones and explain.

SECTION-C (ESSAY) (10marks)

Discuss on the 3 analytical phase and their source of variation.

GOOD LUCK!