HEALTH BENEFITS OF SORGHUM

SORGHUM MAY INHIBIT CANCER TUMOR GROWTH

Compounds in sorghum called 3-Deoxyanthoxyanins (3-DXA) are present in darker-colored

sorgums, and to a lesser extent in white sorghum. Scientists at the University of Missouri
tested extracts of black, red, and white sorghums and found that all three extracts had strong
antiproliferative activity against human colon cancer cells.
Journal of Agricultural & Food Chemistry. 2009 Mar 11;57(5):1797-804

SORGHUM MAY PROTECT AGAINST DIABETES AND INSULIN RESISTANCE

Advanced glycation endproducts (AGEs) are increasingly implicated in the complications of

diabetes. A study from the University of Georgia Neutraceutical Research Libraries showed
that sorghum brans with a high phenolic content and high anti-oxidant properties inhibit
protein glycation, whereas wheat, rice or oat bran, and low-phenolic sorghum bran did not.
These results suggest that “certain varieties of  sorghum bran may affect critical biological
processes that are important in diabetes and insulin resistance.”
Phytotherapy Research. 2008 Aug;22(8):1052-6

SORGHUM IS SAFE FOR PEOPLE WITH CELIAC DISEASE

Up to one percent of the U.S. population (and about ½% worldwide) is believed to have
Celiac Disease, an autoimmune reaction to gluten proteins found in wheat, barley and rye.
While sorghum has long been thought safe for celiacs, no clinical testing had been done until
researchers in Italy made a study. First, they conducted laboratory tests; after those tests
established the likely safety, they fed celiac patients sorghum-derived food products for five
days. The patients experienced no symptoms and the level of disease markers (anti-
transglutaminase antibodies) was unchanged at the end of the five-day period.
Clinical Nutrition. 2007 Dec;26(6):799-805. Epub 2007 Aug 24

SORGHUM MAY HELP MANAGE CHOLESTEROL

Scientists at the University of Nebraska observed that sorghum is a rich source of

phytochemicals, and decided to study sorghum’s potential for managing cholesterol. They
fed different levels of sorghum lipids to hamsters for four weeks, and found that the healthy
fats in sorghum significantly reduced “bad” (non-HDL) cholesterol.  Reductions ranged from
18% in hamsters fed a diet including 0.5% sorghum lipids, to 69% in hamsters fed a diet
including 5% sorghum lipids.  “Good” (HDL) cholesterol was not affected. Researchers
concluded that “grain sorghum contains beneficial components that could be used as food
ingredients or dietary supplements to manage cholesterol levels in humans.”
Journal of Nutrition. 2005 Sep;135(9):2236-40

ADVANTAGES OF SORGHUM OVER MAIZE IN SOUTH AFRICAN DIETS

Sorghum has been widely consumed as a staple food and in beverages throughout Africa.
More recently, corn has replaced sorghum in some areas. Researchers from the University of
Witwatersrand Medical School in South Africa believe that “the change of the staple diet of
Black South Africans from sorghum to maize (corn) is the cause of the epidemic of squamous
carcinoma of the esophagus.” They link the cancers to Fusarium fungi that grow freely on
maize but are far less common on sorghum and note that “countries in Africa, in which the
staple food is sorghum, have a low incidence of squamous carcinoma of the esophagus.”
Medical Hypotheses. 2005;64(3):658-60

ANTIOXIDANTS IN SORGHUM HIGH RELATIVE TO OTHER GRAINS AND TO FRUITS

Joseph Awika and Lloyd Rooney, at Texas A&M University, conducted an extensive review
of scores of studies involving sorghum, and concluded that the phytochemicals in sorghum
“have potential to signiciantly impact human health.”  In particular, they cited evidence that
sorghum may reduce the risk of certain cancers and promote cardiovascular health. Click
here to download the full paper.
Phytochemistry. 2004 May;65(9):1199-221

SORGHUM MAY HELP TREAT HUMAN MELANOMA

Scientists in Madrid studied the effect of three different components from wine and one from
sorghum, to gauge their effects on the growth of human melanoma cells. While results were
mixed, they concluded that all four components (phenolic fractions) “have potential as
therapeutic agents in the treatments of human melanoma” although the way in which each
slowed cancer growth may differ.
Journal of Agricultural & Food Chemistry. 2001 Mar;49(3):1620-4