Name: _______________________

It’s Not You It’s Me:

Date: ________________________
Cells Splitting
Pd. _______
1. Go to the following website: https://www.hhmi.org/biointeractive/eukaryotic-cell-cycle-and-cancer
2. Click on STAR CLICK AND LEARN
3. Read through the BACKGROUND and answer the associated questions.
4. After the background, each phase of the cell cycle can be clicked to view further information.

1. Why is cell division important for both unicellular and multicellular organisms?

2. Why does cell division remain important to an adult organism even after it is fully developed?

3. Cells divide, differentiate, or die. What is differentiation?

4. What is apoptosis? What is its purpose?

5. What happens if cell cycle regulators don’t function properly?

6. CELL CYCLE (fill in the table below)

Phase What Happens? Checkpoint

G1

G0 N/A

G2

CELL CYCLE REGULATORS AND CANCER

1. What are cell cycle regulators? Include an example of a stimulatory and inhibitory protein.

2. Cancer is the result of an improperly regulated cell cycle. Describe two reasons why cells can form
tumors.

3. Normally, tumor suppressor genes inhibit the cell cycle. How do mutated tumor suppressor genes affect
the cell cycle?
During your cell cycle simulation, you had time to think about your choices and were able to make
changes. Cancer cells are abnormal cells that have uncontrolled cell division. Explain how a mistake in
the steps of the cell cycle could lead to cancerous cells forming.
Be sure the include the following:
• How you can tell if a cell is cancerous
• What steps are included in the normal cell cycle
• Describe at least THREE different errors in the cell cycle that can lead to the rise of cancerous cells
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