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Asthma
Asthma is a chronic inflammatory disorder of the airways in which many cells play a
role, including mast cells, eosinophils, T-lymphocytes and neutrophils. In susceptible
individuals, this inflammation causes symptoms which are usually associated with widespread
but variable inflow obstruction that is often reversible either spontaneously or with treatment.
Asthma tends to occur in children with a tendency to react with hypersensitivity to
allergens. Mast cells release histamine and leukotrienes that result in diffuse obstructive and
restrictive airway disease.
Mechanism of disease
Asthma primarily affects the small airways and involves three separate processes: bronchospasm,
inflammation of bronchial mucosa, and increased bronchial secretions (mucus).
Therapeutic Management
Child with mild, persistent Asthma
Usually is prescribed an inhaled anti-inflammatory corticosteroid as Fluticasone daily.
Child with moderate persistent symptoms
Usually is prescribed an inhaled anti-infammatory corticosteroid daily and a long-acting
bronchodilator at bedtime.
Pneumonia
Cause. Possibly bacterial (pneumococcal, streptococcal, staphylococcal, so chlamydial)
or Viral (Respiratory syncytial virus RSV)
Pneumococcal Pneumonia: with this, children may have blood-tinged sputum as exudative
serum and red blood cells invade the alveoli. After 24-48 hours, the alveoli are no longer filled
with red blood cells and serum, but fibrin, leukocytes and pneumococci. At this point, the child’s
cough no longer raises blood-tinged sputum but thick purulent material.
S/s: high fever, nasal flaring, chest pain, chills, dyspnea. Taychypnea and tachycardia develop.
Crackles may be present. Breath sounds become bronchial.
Therapeutic Management:
Either Ampicillin or a third-generation cephalosporin.
Humidified oxygen
Chlamydial Pneumonia: Symptoms usually begin gradually with nasal congestion and a sharp
cough. It progress to tachypnea with wheezing and crackles. It is treated with Erythromycin.
Viral Pneumonia: There may be diminished breath sounds and fine crackles.
Therapeutic management:
Antipyretic for the fever
Intravenous fluid if the child is dehydrated or exhausted from feeding