John Smith 57 M Married Roman Catholic

Polymyolitis

Azathioprine - Imuran Immunosuppresant Inhibits DNA, RNA, and protein PO Rheumatoid - Rheumatoid - Pregnancy - Fever Assessment
History:
- Asazan synthesis and antagonizes arthritis – arthritis Use - Lactation - Chills Allergy to azathioprine;
purine synthesis. It also 1mg/kg/day for 6-8 only with adults - Alcoholism - Bone marrow depression; rheumatoid arthritis patients
previously treated with
inhibits mitosis and interferes weeks. May adjust meeting criteria - Chronic liver disease characterized by leucopenia, alkylating agents; pregnancy or 
with cellular metabolism of dose gradually to for classic - Immune deficiencies thrombocytopenia or anemia male partners of women trying
susceptible organisms. 2.5mg/kg/day if rheumatoid - Blood dyscrasias - Anorexia to become pregnant; lactation
- Physical:
Azathioprine should be needed. arthritis and - Hypersensitivity to drug - Nausea T; skin color, lesions;
discontinued as soon as oral not responding -Diarrhea liver evaluation, bowel sounds;
LFTs, renal function tests, CBC
therapy can be introduced. to conventional - Rash
management. - Alopecia Interventions
- Give drug IV if oral
administration is not possible;
-Chronic switch to oral route as soon as
ulverative possible.
- Administer in divided daily
colitis doses or with food if GI upset
- Myasthenia occurs.
gravis
BLACK BOX WARNING:
- Chron’s Monitor blood counts regularly;
disease severe hematologic effects
may require the discontinuation
of therapy; increases risk of 
neoplasia.

Teaching points
- Take drug in divided doses with
food if GI upset occurs.
- Avoid infections; avoid crowds
or people who have infections.
Notify your physician at once if 
you are injured.
- Notify your health care provider 
if pt is pregnant or 
wishes to become pregnant.

Alexa-Rae P. Zagado SNBC Ronald Ramo RN, MAN

BSN-III 4/10/20