Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Session / Wednesday, May 19/1:30 PM-4:00 PM / Room 291-292 (Second Level), Morial Convention Center
J. Kim1, H. kang1, J. Kim1, M. Kim1, S. Kim1, H. Yun1, J. Ahn2, C. Kim1, K. Kim1, J. Song1
1The Catholic University of Korea, College of Medicine, Seoul, Korea, 2The Catholic University of Korea, College of Medicine, seoul, Korea
Introduction
Systemic mastocytosis is a rare disease characterized by an abnormal proliferation of mast cells that infiltrate the skin, bone marrow,
spleen, liver, and lymph nodes. The release of mast cell mediators such as histamine causes systemic attack, with flushing, pruritus,
headache, gastrointestinal symptoms, and even vascular collapse with syncope. To the best of our knowledge severe lymphadenopathy of
neck and pleural involvement of systemic mastocytosis were not reported. We present a case with various manifestations such as
pulmonary, intestinal, bone, and lymph node involvement.
Case Report
A 77-year-old-woman presented with palpable neck mass and headache for 1 month. She did not complained of flushing and pruritus.
Physical examination showed bilateral cervical lymphadenopathy and decreased breathing sound in right lung field. There was no skin
lesion. Laboratory finding showed eosinophilia, elevated liver enzyme, and anemia. Plain chest films and chest computed tomography
(CT) showed large pleural effusion in right hemithorax. Neck CT also revealed multiple bilateral well defined lymphadenopathy along
cervical chain(Fig 1).
Fig 1 - Neck CT