ANNA UNIVERSITY OF TECHNOLOGY, COIMBATORE

AFFILIATED INSTITUTIONS
CURRICULUM 2007

B.E - BIO MEDICAL ENGINEERING

SEMESTER VII
(Applicable to the students admitted from the Academic Year 2007-2008)

Code No. Course Title L T P M C

THEORY
070380023 Neural Networks and Application 3 0 0 100 3
070380029 Computers in Medicine 3 0 1 100 4
070380030 Medical Optics 3 0 0 100 3
070380034 Diagnostic and Therapeutic Equipments II 3 0 0 100 3
Elective II 3 0 0 100 3
Elective III 3 0 0 100 3
PRACTICAL
070380035 Hospital Training 0 0 4 100 2
070380036 Diagnostic and Therapeutic Equipments Lab 0 0 3 100 2

SEMESTER VIII
(Applicable to the students admitted from the Academic Year 2007-2008)

Code No. Course Title L T P M C

THEORY
Hospital Management 3 0 0 100 3
Elective IV 3 0 0 100 3
Elective V 3 0 0 100 3
PRACTICAL
Project Work 0 0 12 200 6
Comprehension** 0 0 2 -

** No Examinations

LIST OF ELECTIVES - VII SEMESTER

(Applicable to the students admitted from the Academic Year 2007-2008)

Code No. Course Title L T P M C

070380037 AI and Pattern Recognition 3 0 0 100 3
070380038 Physiological Modeling 3 0 0 100 3
070380039 Medical Informatics 3 0 0 100 3
070380040 Rehabilitation Engineering 3 0 0 100 3
070380041 Total Quality Management 3 0 0 100 3
070380042 ICU & Operation theatre Equipments 3 0 0 100 3
 LIST OF ELECTIVES - VIII SEMESTER
(Applicable to the students admitted from the Academic Year 2007-2008)

Code No. Course Title L T P M C

Bio Fluids and Dynamics 3 0 0 100 3
Medical Imaging Techniques 3 0 0 100 3
Assist Devices 3 0 0 100 3
VLSI Design 3 0 0 100 3
Computer Networks 3 0 0 100 3
Biotelemetry 3 0 0 100 3
070380023 NEURAL NETWORKS AND ITS APPLICATION

1. ADAPTIVE LINEAR COMBINER 9

Elementary neurophysiology and biological neural network-Artificial neural network, Adeline
and Madeline.

2. BACK PROPOGATION AND ASSOCIATE MEMORY 9

Back propogation network, generalized delta rule, Bidirectional associate memory, Hopefield
memory architecture.

3. BOLTZMANN’S MACHINES AND COUNTER PROPOGATION NETWORK 9

Simulated Annealing, Boltzman completion network, Boltzman input output network, counter
propogation network.

4. SELF-ORGANISING MAPS AND ADAPTIVE RESONANCE THEORY 9

Self organizing map,feature map classifier, adaptive resonance theory network, ART1,ART2.

5. SPATIOTEMPORAL NETWORKS AND NEOCOGNITRON 9

Architecture of spatiotemporal networks, Sequential competitive avalanche field, Neocognitron
architecture and dataprocessing.

TOTAL : 45
TEXT BOOK
1. J.A. Freeman & David.M. Skapura, Neural networks, Algorithms applications and
programming techniques, Addison Wesley, 1991. ISE Reprint 1999.

REFERENCES
1. David M. Skapura, “Building Neural Networks”, Addison Wesley, 1996.
2. Bose, “Neural Network Fundamentals with graphs, algorithms and applications”, Tata
McGraw-Hill, 1995.
070380029 COMPUTERS IN MEDICINE

1. OVERVIEW OF COMPUTER HARDWARE PC-AT 9

8086 architecture, system connections, Instruction set & programming, Microcontrollers,
Motherboard and its logic, RS232-C and IEEE bus standards, CRT controllers, FDC, HDC and
Post sequence, PC based video card, modems and networking.

2. SYSTEM DESIGN 9
Multichannel computerised ECG, EMG and EEG data acquisition, storage and retrieval,
transmission of signal and images.

3. COMPUTERS IN PATIENT MONITORING 9

Physiological monitoring, automated ICU, computerised arrhythmia monitoring, information
flow in a clinical lab, computerised concepts, interfacing to HIS.

4. COMPUTERS IN MEDICAL SYSTEMS MODELLING 9

Radiotherapy, drug design, drug delivery system, physiological system modelling and simulation.

5. COMPUTERS IN MEDICAL RESEARCH 9

Role of expert systems, pattern recognition techniques in medical image classification, ANN
concepts.

TOTAL : 45
TEXT BOOKS
1. R.D.Lee, “Computers in Medicine”, Tata McGraw-Hill, New Delhi, 1999.
2. Douglas V.Hall, “Microprocessors and Interfacing : Programming and hardware”,
McGraw-Hill, Singapore, 1999.
070380030 MEDICAL OPTICS

1. OPTICAL PROPERTIES OF THE TISSUES 9

Refraction, Scattering, absorption, light transport inside the tissue, tissue properties, Light
interaction with tissues, optothermal interaction, fluorescence, speckles.

2. INSTRUMENTATION IN PHOTONICS 9
Instrumentation for absorption, scattering and emission measurements, excitation light sources –
high pressure arc lamp, solid state LEDs, LASERs, optical filters, polarisers, solid state detectors,
time resolved and phase resolved detectors.

3. APPLICATIONS OF LASERS 9
Laser in tissue welding, lasers in dermatology, lasers in ophthalmology, otolaryngology, urology.

4. OPTICAL HOLOGRAPHY 9
Wavefronts, Interference patterns, principle of hologram, optical hologram, applications.

5. SPECIAL TECHNIQUES 9
Near field imaging of biological structures, in vitro clinical diagnostic, fluorescent spectroscopy,
photodynamic therapy.

TOTAL : 45
TEXT BOOKS
1. Tuan Vo Dirh, “Biomedical photonics – Handbook”, CRC Press, Bocaraton, 2003 (Unit I
– III, V).
2. Leon Goldman, M.D., & R.James Rockwell, Jr., “Lasers in Medicine”, Gordon and
Breach, Science Publishers Inc., New York, 1971 (Unit IV).
070380034 DIAGNOSTIC AND THERAPEUTIC EQUIPMENTS – II

UNIT I ULTRASONIC TECHNIQUES FOR DIAGNOSIS 10

Basic principles of Echo technique, display techniques A, B, M modes, Echo cardiograms, Echo
encephalogram, Ultrasonic applied as diagnostic tool in ophthalmology, obstetrics and
gynaecology.
UNIT II PATIENT MONITORING AND BIOTELEMETRY 9
Patient monitoring system – ICU, post operative, ICCU, single channel telemetry, multichannel
telemetry, frequency allotment, radiopill. Tranmsmission of Biosignals over telephone lines.

UNIT III DIATHERMY 9

Clinical applications of electrotherapy, short wave diathermy, ultrasonic diathermy, microwave
diathermy, surgical diathermy unit, IR lamps, UV lamps.

UNIT IV SPECIAL DIAGNOSTIC TECHNIQUES 9

Principles of Cryogenic technique and application, Endoscopy, Laproscopy, Thermography.

UNIT V PATIENT SAFETY 8

Sources of leakage current, Micro and Macro shock, monitoring circuits, earthing schemes.
TOTAL : 45
TEXT BOOKS
1. Khandpur R.S, “Handbook of Biomedical Instrumentation”, Tata McGraw-Hill, New
Delhi, 1997.

REFERENCES
1. John G.Webster, “Medical Instrumentation Application and Design”, John Wiley and
sons, New York, 1998.
2. Joseph J.Carr and John M.Brown, “Introduction to Biomedical equipment technology”,
John Wiley and sons, New York, 1997.
070380035 HOSPITAL MANAGEMENT

1. NEED AND SCOPES OF CLINICAL ENGINEERING 9

Clinical engineering program, educational responsibilities, role to be performed by them in
hospital, staff structure in hospital.

2. NATIONAL HEALTH POLICIES 9

Need for evolving health policy, health organization in state, health financing system, health
education, health insurance, health legislation.

3. TRAINING AND MANAGEMENT OF TECHNICAL STAFF IN HOSPITAL 9

Difference between hospital and industrial organization, levels of training, steps of training,
developing training program, evaluation of training, wages and salary, employee appraisal
method.

4. STANDARDS AND CODES IN HEALTH CARE 9

Necessity for standardization, FDA, Joint Commission of Accreditation of hospitals, ICRP and
other standard organization, methods to monitor the standards.

5. COMPUTER IN MEDICINE 9
Computer application in ICU, X-Ray department, laboratory administration, patient data,
medical records, communication, simulation.

TOTAL : 45
TEXT BOOKS
1. Webster J.C. and Albert M.Cook, “Clinical Engineering Principle and Practice”, Prentice
Hall Inc., Englewood Cliffs, New Jersey, 1979 (Unit I).
2. Goyal R.C., “ Handbook of hospital personal management”, Prentice Hall of India, 1996
(Unit II – V).
070380036 DIAGNOSTIC AND THERAPEUTIC EQUIPMENT LAB

1) Study of ultrasonic transducers and displays.

2) Study of pacemaker.
3) Multichannel biotelemetry.
4) Shortwave and ultrasonic diathermy.
5) Multichannel data acquisition system.
6) Simulation of biosignals.
7) Analysis of ECG signals.
8) Analysis of EEG signals.
9) Leakage current and electrical safety measurements.
10) Mini Project.
 ELECTIVES
070380037 ARTIFICIAL INTELLIGENCE AND PATTERN RECOGNITION

UNIT I INTRODUCTION 9
Definition of AI, Intelligent agents, perception and language processing, problem solving,
searching, heuristic searching, game playing, Logics, logical reasoning.

UNIT II BASIC PROBLEM SOLVING METHODS 9

Forward Vs Background, knowledge representation, frame problems, heuristic functions, weak
methods of matching.

UNIT III PRINCIPLES OF PATTERN RECOGNITION 9

Patterns and features, training and learning in pattern recognition, pattern recognition approach,
different types of pattern recognition.

UNIT IV DECISION MAKING 9

Baye’s theorem, multiple features, decision boundaries, estimation of error rates, histogram,
kernels, window estimaters, nearest neighbour classification, maximum distance pattern
classifier, adaptive decision boundaries.

UNIT V CLUSTER ANALYSIS AND FEATURE EXTRACTION 9

Unsupervised learning, hierarchical clustering, Graph theories approach to pattern clustering,
fuzzy pattern classifier, application of pattern recognition in medicine.
TOTAL : 45

TEXT BOOKS
1. Elain Rich and Kevin Knight, “Artificial Intelligence”, 2nd Edition, Tata McGraw-Hill,
1993.
2. Earl Gose, Richard Johnsonbaugh, Steve Jost, “Pattern Recognition and Inmage
Analysis”, Prentice Hall of India Pvt. Ltd., New Delhi, 1999.
070380038 PHYSIOLOGICAL MODELLING

UNIT I INTRODUCTION 9
System concept, system properties, piece-wise linear approximation, electrical analog for
compliance, thermal storage, pulse response of first order systems, response of resistant and
compliance system.

UNIT II TRANSFER FUNCTIONS 9

Transfer functions and its use, engineering concept in coupled system, example of Transformed
signals.

UNIT III IMPEDANCE CONCEPT 9

Circuits for the Transfer function with impedance concept, prediction of performance, periodic
signals.

UNIT IV FEEDBACK SYSTEMS 9

Characteristics of physiological feedback systems, uses and testing of system stability.

UNIT V SIMULATION OF BIOLOGICAL SYSTEMS 9

Simulation of thermal regulation, pressure and flow control in circulation, occulo motor system,
endocrinal system, functioning of receptors.

TOTAL : 45
REFERENCES
1. William B.Blesser, “AS System approach to Bio-medicine”, McGraw-Hill book co., New
York, 1969.
2. Manfreo clynes and john H.Milsum, “Bio-medical engineering system”, McGraw-Hill
book co., NewYork, 1970.
3. Douglas S.Regs, “Control theory and physiological feedback mechanism”, The William
& Williams co., Baltimore, 1970.
070380039 MEDICAL INFORMATICS

1. MEDICAL DATABASE IMPLEMENTATION 9

Medical data acquisition and database systems: PC based mutlichannel data acquisition system;
storage, analysis and retrieval techniques.

2. VISUAL BASIC 9
Visual programming concepts; visual Basic environment, tools and controls; Dynamic data
exchange; VB based Medical information System.

3. COMPUTERS IN SYSTEM DESIGN 9

Hospital Information System its design and functional characteristics; Principles and application
of Artificial Intelligence, Pattern Recognition, Neural Network and Fuzzy Logic in Medicine.

4. MULTIMEDIA AND VIRTUAL REALITY APPLIED TO MEDICINE 9

Basic concepts of Multimedia; Design of Multimedia information systems; Components of virtual

reality; Virtual reality applications in medicine.

5. COMPUTERS IN MEDICAL RESEARCH 9

Medical Informatics and its levels; Design and development of educational packages on medical
sciences; Integrated design concepts; Interactive multimedia, Virtual and digital libraries, Internet
and its applications.

TOTAL : 45
TEXT BOOK
1. R.D.Lele, “Computer in Medicine”, Tata McGraw-Hill, New Delhi, 1997.
REFERENCES
1. Tay Vaughan, “Multimedia making it work’, Tata McGraw-Hill, New Delhi, 1997.
2. Davis Chapman, “Teach Yourself Visual Basic 6 in 21 days”, New Delhi, 1997.
3. Harold Sackman, “Biomedical Information Technology’, Academic Press, New York,
1997.
4. Mary Brth Fecko, “Electronics Resources: Access and Issues”, Bowker and Saur,
London, 1997
070380040 REHABILITATION ENGINEERING

UNIT I PROSTHETIC AND ORTHOTIC DEVICES 9

Hand and arm replacement, different types of models for externally powered limb
prosthetics, feedback in orthotic system, material for prosthetic and orthotic devices,
mobility aids.

UNIT II AUDITORY AND SPEECH ASSIST DEVICES 9

Types of deafness, hearing aids, application of DSP in hearing aids, vestibular implants,
Voice synthesizer, speech trainer.

UNIT III VISUAL AIDS 9

Ultra sonic and laser canes, Intra ocular lens, Braille Reader, Tactile devices for visually
challenged, Text voice converter, screen readers.

UNIT IV MEDICAL STIMULATOR 9

Muscle and nerve stimulator, Location for Stimulation, Functional Electrical Stimulation,
Sensory Assist Devices

UNIT V REHABILITATION MEDICINE AND ADVOCACY 9

Physiological aspects of Function recovery, Psychological aspects of Rehabilitation
therapy, Legal aspect available in choosing the device and provision available in education,
job and in day-to-day life.

TOTAL:45 PERIODS

REFERENCES

1. Levine.S.N.Editor, Advances in Bio Medical Engineering and Medical Physics, Inter

University Publication, New York 1968.
2. Albert M.Cook and Webster J.G, Therapeutic Medical devices, Prentice Hall Inc.,
NewJersy, 1982.
3. Reswick.J, What is Rehabilitation Engineering, Annual review of Rehabilitation-
volume2, Springer-Verlag, New York 1982. Hanfredclynes, “ Biomedical
Engineering Systems’, McGraw Hill, 1999
4.“Handbook of Physical Medicine & Rehabilitation’, W.B.Saunders Publications,
2003
070380041 TOTAL QUALITY MANAGEMENT

1. INTRODUCTION 9
Definition of Quality, Dimensions of Quality, Quality Planning, Quality costs - Analysis
Techniques for Quality Costs, Basic concepts of Total Quality Management, Historical Review,
Principles of TQM, Leadership – Concepts, Role of Senior Management, Quality Council,
Quality Statements, Strategic Planning, Deming Philosophy, Barriers to TQM Implementation.

2. TQM PRINCIPLES 9
Customer satisfaction – Customer Perception of Quality, Customer Complaints, Service Quality,
Customer Retention, Employee Involvement – Motivation, Empowerment, Teams, Recognition
and Reward, Performance Appraisal, Benefits, Continuous Process Improvement – Juran Trilogy,
PDSA Cycle, 5S, Kaizen, Supplier Partnership – Partnering, sourcing, Supplier Selection,
Supplier Rating, Relationship Development, Performance Measures – Basic Concepts, Strategy,
Performance Measure.

3. STATISTICAL PROCESS CONTROL (SPC) 9

The seven tools of quality, Statistical Fundamentals – Measures of central Tendency and
Dispersion, Population and Sample, Normal Curve, Control Charts for variables and attributes,
Process capability, Concept of six sigma, New seven Management tools.

4. TQM TOOLS 9
Benchmarking – Reasons to Benchmark, Benchmarking Process, Quality Function Deployment
(QFD) – House of Quality, QFD Process, Benefits, Taguchi Quality Loss Function, Total
Productive Maintenance (TPM) – Concept, Improvement Needs, FMEA – Stages of FMEA.

5. QUALITY SYSTEMS 9
Need for ISO 9000 and Other Quality Systems, ISO 9000:2000 Quality System – Elements,
Implementation of Quality System, Documentation, Quality Auditing, TS 16949, ISO 14000 –
Concept, Requirements and Benefits.

TOTAL : 45
TEXT BOOK
1. Dale H.Besterfiled, et al., Total Quality Management, Pearson Education, Inc. 2003.
(Indian reprint 2004). ISBN 81-297-0260-6.

REFERENCES
1. James R.Evans & William M.Lidsay, The Management and Control of Quality, (5th
Edition), South-Western (Thomson Learning), 2002 (ISBN 0-324-06680-5).
2. Feigenbaum.A.V. “Total Quality Management, McGraw Hill, 1991.
3. Oakland.J.S. “Total Quality Management Butterworth – Hcinemann Ltd., Oxford. 1989.
4. Narayana V. and Sreenivasan, N.S. Quality Management – Concepts and Tasks, New
Age International 1996.
5. Zeiri. “Total Quality Management for Engineers Wood Head Publishers, 1991.
070380042 ICU AND OPERATION THEATRE EQUIPMENTS

UNIT I

ICU EQUIPMENT: Suction apparatus – Different types; Sterilizers – Chemical, Radiation,

Steam for small and large units. Automated drug delivery systems – Infusion pumps, closed loop
control infusion system, implantable infusion system. (9)

UNIT II

CRITICAL CARE EQUIPMENT: Hemo dialysis Machine – Different types of Dialyzers.

Membranes, Machine controls and measurements, Heart Lung Machine –different types of
oxygenators, peristaltic pumps, Incubators. (9)

UNIT III

OT EQUIPMENT: Surgical diathermy, Instruments for operation.Anesthesia Equipment –

Humidification, Sterilisation aspects – Boyles apparatus. (9)

UNIT IV

CENTRALIZED SYSTEMS: Centralized Oxygen, Nitrogen, Air supply & Suction.

Centralised Air – Conditioning, Operation theatre table & lighting. (9)

UNIT V

PATIENT SAFETY: Patient electrical safety – Types of hazards – Natural protective

mechanisms against electricity – Leakiage current – Inspection of grounding and patient
isolation, Hazards in operation rooms – ICCU and IMCUs – Opto couplers and Pulse
Transformers. (9)

TOTAL : 45
TEXT BOOK:
1. Khandapur R S, “Handbook of Bio-Medical Instrumentation”, Second Edition, Tata McGraw
Hill Publishing Company, Ltd., 2003.

REFERENCE BOOKS:
1. John G Webster, “Medical Instrumentation- Application and Design”, John Wiley & Sons,
Inc., New York, Third
Edition,1999.
2. Joseph Dubovy, “Introduction To Bio-Medical”, McGraw Hill Co., 1978.
3. Terry Bahila, “Biomedical And Clinical Engineering”, Prentice Hall Inc., 1981.
 BIO-FLUID AND DYNAMICS

1. INTRODUCTORY CONCEPTS 9
Fluids and non-fluids, continuum coordinate systems, force and moments, stress at a point, rate of
strain, properties of fluids, classification of fluids.

2. FLUID FLOW 9
Different types of fluid flows, laminar and turbulent flow, transition from laminar to turbulent
flow, laminar flow-annulus, laminar flow between parallel plates, measurement of viscosity.

3. BOUNDARY LAYER FLOW 9

Development of boundary layer, estimates of boundary layer thickness, boundary layer equation,
nature of turbulence, smooth and rough surface, boundary layer separation.

4. PRESSURE AND FLOW IN BLOOD VESSELS 9

Friction loss in flow in a tube, velocity distribution of aortic system, waveform of pressure and
velocity in aorta, wave reflections and impedance in arterial segments, blood flow in veins and
blood flow in capillaries.

5. ANALYSIS OF CARDIO VASCULAR DYNAMICS 9

Control theory and system analysis, mechanical analysis of circulatory systems, basic concept of
myocardial mechanics, index of contractibility, fluid dynamics of aortic and mitral valves.

TOTAL : 45
REFERENCES
1. K.L.Kumar, “Engineering fluid mechanics”, Eurasia Publishing House (P) Ltd., New
Delhi, 1998.
2. D.H.Bergel, “Cardiovascular fluid dynamics”- Vol. I, Academic press, London & New
York, 1972.
 MEDICAL IMAGING TECHNIQUES

1. DIFFERENT MODES OF MEDICAL RECORDING 9

Quality assurance and image improvement in diagnostic radiology with X-Rays, specific Quality
assurance tests for X-rays, need for sectional images, principles of sectional images recording,
computer tomography with different trajectories.

2. RADIOISOTOPIC IMAGES 9
Radio isotopic imaging equipments, radiation detectors, radionuclide for imaging, static and
dynamic planar scintillography.

3. NUCLEAR MAGNETIC RESONANCE IMAGING 9

Development of NMR, relaxation processes and their measurements, MRI-Image acquisition and
reconstruction, MRI safety.

4. MATHEMATICS OF IMAGE FORMATION AND IMAGE PROCESSING 9

Concept of object and image, general image processing problem, discrete fourier representation
and models for imaging, image restoration, image sampling, perception of moving images.

5. COMPUTER REQUIREMENT FOR IMAGING SYSTEM 9

Single/ multi user system, transferring of images, processing speed, display of medical images, 3-
D image display and its clinical applications.

TOTAL : 45
TEXT BOOK
1. Steve Webb, “The physics of medical imaging”, Adam Hilger, Bristol, England,
Philadelphia, USA, 1988.
 ASSIST DEVICES

1. CARDIAC ASSIST DEVICES 9

Principle of External counter pulsation techniques, intra aortic balloon pump, Auxillary ventricle
and schematic for temporary bypass of left ventricle, prosthetic heart valves.

2. HEMODIALYSERS 9
Artificial kidney, Dialysis action, hemodialyser unit, membrane dialysis, portable dialyser
monitoring and functional parameters.

3. HEARING AIDS 9
Common tests – audiograms, airconduction, boneconduction, masking techniques, SISI, Hearing
aids – principles, drawbacks in the conventional unit, DSP based hearing aids.

4. PROSTHETIC AND ORTHODIC DEVICES 9

Hand and arm replacement – different types of models, externally powered limb prosthesis,
feedback in orthodic system, functional electrical stimulation, sensory assist devices.
5. RECENT TRENDS 9
Transcutaneous electrical nerve stimulator, bio-feedback.

TOTAL : 45
TEXT BOOKS
1. Levine S.N. (ed), “Advances in Bio-medical engineering and Medical physics”, Vol. I, II,
IV, inter university publications, New York, 1968 (Unit I, IV, V).
2. Kopff W.J, “Artificial Organs”, John Wiley and sons, New York, 1976. (Unit II ).
3. Albert M.Cook and Webster J.G, “Therapeutic Medical Devices”, Prentice Hall Inc.,
New Jersey, 1982 (Unit III).
 VERY LARGE SCALE INTEGRATED CIRCUIT DESIGN

1. MOS TECHNOLOGY AND CIRCUITS 9

MOS Technology and VLSI, Process parameters and considerations for BJT, MOS and CMOS,
Electrical properties of MOS circuits and Device modelling.

2. MOS CIRCUIT DESIGN PROCESS 9

MOS layers, Stick diagram, Layout diagram, Propagation delays, Examples of combinational
logic design, Scaling MOS circuits.

3. DIGITAL CIRCUITS AND SYSTEMS 9

Programmable Logic Array (PLA) and finite state machines, Design of ALU’s Memories and
Registers.

4. ANALOG VLSI AND HIGH SPEED VLSI 9

Introduction to analog VLSI, Models for analog switches, active resistors, current sources / sinks,
current references, BJT and CMOS operational amplifiers for simulation. Layout of typical
circuits like common source amplifier, current source and differential amplifier, Sub-micron
technology and GaAs VLSI technology.

5. HARDWARE DESCRIPTION LANGUAGES 9

VHDL Background and basic concepts, Structural specification of hardware and Design
organisation and parameterization.

TOTAL : 45
TEXT BOOKS
1. Dougles A. Pucknell and Kamran Eshrafhian, Basic VLSI Design systems and circuits”,
Prentice Hall of India Pvt., Ltd.
2. Randall L.Geiger and P.E.Allen, “VLSI design techniques for analog and digital
circuits”, McGraw-Hill Int., Co., 1990.
3. Peter J.Ashenden, “The Designer’s guide to VDNL”, Harcourt Asia Pvt., Ltd., 1995.

REFERENCES
1. Amar Murkherjee, “Introduction to NMOS and CMOS VLSI system design”, Prentice
Hall, 1986.
2. Fabious.E., “Introduction to VLSI design”, McGraw-Hill, 1990.
3. Navabi.Z., “VHDL analysis and modeling of digital systems”, McGraw-Hill, 1983.
4. Mohammed Ismail and Terri Fiez, “Analog VLSI, Signal and Information Processing”,
McGraw-Hill, 1994.
5. Neil H.E. Weste, Kamaran Eshraghian, Principles of CMOS VLSI Design”, Addison
Wesley, 1998.
 COMPUTER NETWORKS

1. DATA COMMUNICATION CONCEPTS 8

Transmission media – Data encoding – Interface and Modems – Multiplexing – Error detection
and correction – Digital subscriber line – Circuit switching – Packet switching – Message
switching.

2. WIDE AREA NETWORKS 10

ISO – OSI layered architecture – Function of the layers – Data link protocols – HDLC, LAPB,
LAPD, Inter networking devices – Repeaters, Bridges, Routers, Routing algorithms – Distance
vector routing, link state routing, X.25 protocol, congestion control.

3. FRAME RELAY AND ATM NETWORKS 9

Frame relay operation – layers and traffic control; ATM networks – Architecture switching,
layers service classes.

4. LOCAL AREA NETWORK 10

LAN topology – Ethernet – Token bus – Token ring – FDDI – Wireless LAN, ATM LAN – IEEE
802 Medium access control layer standard – Random access protocols – ALOHA – Slotted
ALOHA.

5. OSI LAYERS 8
Transport layer issues – Session layer – Synchronization – Presentation layer – Encryption,
decryption, Application layer – Message handling system, file transfer, virtual terminal – E-mail.

TOTAL : 45
TEXT BOOK
1. William Stallings, “Data and Computer Communication”, sixth edition, Pearson
education Asia, 2000.

REFERENCES
1. Behrouz A, Forouzan, “Data Communication and Networking”, second edition, Tata
McGraw-Hill, 2000.
2. Fred Halsall, “Data Communication, Computer networks and Open Systems”, Fourth
edition, Addison Wesley, 1995.
3. Andrew S.Tanenbaum, “Computer networks”, Third edition, PHI, 1996, Chapter 4.
 BIOTELEMETRY

UNIT I :INTRODUCTION TO TELEMETRY PRINCIPLE 9

Basic system – classification – Non electrical telemetry systems – Voltage and Current telemetry
systems – local transmitters and converters – frequency telemetering – Power Line Carrier
Communication (PLCC).

UNIT II: BIOTELEMETRY PRINCIPLES: 9

Introduction – Physiological parameters adaptable to Biotelemetry Components of Biotelemetry
system: Transmitters – Receivers – Transmission lines – Antennas – Filters – modulation and
multiplexing methods used.
UNIT III RADIOPILL IN BIOTELEMETRY
Radio pill Telemetry, Portable and Landline Telemetry unit, frequency allotment , Applications in
Gastroenterology .

UNIT IV: BIOTELEMETRY SYSTEMS: 9

Radio telemetry – Infrared telemetry – ultrasonic telemetry – storage telemetry – wired telemetry
– wireless telemetry – single channel telemetry system – temperature telemetry system – multi
channel telemetry system – multipatient telemetry – implantable telemetry system.

UNIT V: APPLICATIONS OF BIOTELEMETRY: 9

Application in cardio vascular system – Application in neurology – Application in monitoring of
Biomechanical parameters – Application in urology – Application in monitoring and control of
Diabetes mellitus – Application in sports and medicine – Application in patient care.

Total 45
TEXT BOOK:
1. John G Webster, “Encyclopedia of Medical devices and Instrumentation – Vol.1”, John Wiley
and Sons, 1988

REFERENCE BOOKS:
1. Patranabis D, “Telemetry Principles”, TMH, New Delhi, 1999.
2. Leslie Cromwell, Fred J Weibell and Erich A Pfeiffer, “Biomedical Instrumentation and
Measurements”, PHI, Second
Edition, 2003.
3. Khandpur R S, “Handbook of Biomedical Instrumentation”, Tata McGraw Hill, New
Delhi,1987