INSTRUCTIONS:

Input the patient's weight in pounds in the yellow box and press "enter" on your keyboard.
To calculate the toxic dose of a 1:1 mixture, mark the two corresponding yellow boxes with an "x"
Toxic Dose Lidocaine 4.5 mg/kg
Toxic Dose Lidocaine with Epi 7 mg/kg
Toxic Dose Marcaine 2 mg/kg

Weight of Patient lbs

0 kg

LA Solution Concentration
2% Lidocaine 20 mg/ml
1% Lidocaine 10 mg/ml
0.5% Marcaine 5 mg/ml
0.25% Marcaine 2.5 mg/ml

Toxic Dose = (ml/mg) x (mg/kg) x kg

Toxic Dose 1:1 Mix = TD1 when TD1<TD2

TOXIC DOSES Weight-Based Equation (ml) Max Total Dose (ml)

2% Lidocaine ml 15
2% Lidocaine with Epi ml 25
1% Lidocaine ml 30
1% Lidocaine with Epi ml 50
0.5% Marcaine ml 35
0.5% Marcaine with Epi ml --- 45
0.25% Marcaine ml 70
0.25% Marcaine with Epi ml --- 90
1:1 Mix ml --- ---
-These calculations assume weight-based toxic doses as defined. Note, these can vary depending on manufacturer a
-These limits are based off recommendations for normal, healthy adults undergoing most routine procedures.
-Toxicity may depend on patient-specific, site-specific and block-specific factors and should be fully assessed on an individual basis.
-For more information on local anesthetic use and recommendations in podiatric surgery, refer to Kihm's Podiatry Institute Update Article, 2011.
-Maximal total recommended doses: Lidocaine plain 300mg, Lidocaine with Epi 500mg; Marcaine plain 175mg, Marcaine with Epi 225mg.
-When weight-based limits exceed maximum total dose limits, maximum total doses are used.
-Lidocaine and marcaine are believed to have additive toxic effects in humans.
-Use at your own discretion. No liability is assumed for overadministration of local anesthetic.
our keyboard.
ow boxes with an "x"

ssed on an individual basis.

Podiatry Institute Update Article, 2011.
175mg, Marcaine with Epi 225mg.