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Normal pulmonary venous Doppler
Dr David Carroll ◉ et al.

Normal pulmonary venous blood flow in the pulmonary veins may be investigated during
echocardiography with spectral Doppler analysis. Perturbations in the normal pulmonary venous
waveform may indicate the presence of diastolic dysfunction and elevated filling pressures in the left
atrium and ventricle. 

Radiographic features

Pulsed wave Doppler (PWD) of the right superior pulmonary vein, which one may insonate from an
apical four-chamber view (A4C), will typically yield a waveform with three positive deflections
(S1,S2,D) and one negative deflection (AR) 1. 

Superior angulation of the transducer from an adequate A4C is often necessary to obtain adequate
visualization of the right upper pulmonary vein. Color flow Doppler insonation of the posteromedial left
atrium should precede use of PWD to ensure optimal alignment with the pulmonary venous flow.
Reduction of the set Nyquist limit is often necessary as the flow velocities of interest are typically
modest.

Pulsed wave Doppler

systolic deflections
positive, referred to as S1 and S2, often indistinguishable and simply referred to as the S
wave
the first (S1) component denotes atrial diastole, with suction of blood into the left atrium
abolished with atrial fibrillation
the second (S2) component occurs when the mitral annulus is apically displaced with
ventricular systole, decreasing left atrial pressure and creating a gradient for forward flow
blunted by mitral regurgitation
diastolic deflections
normally a prominently positive, albeit more diminutive, deflection following the sequential
systolic components
referred to as the D wave
atrial reversal
the downstroke of the D wave will often dip below the baseline, indicating flow away
from the transducer
referred to as the AR wave, corresponding to atrial contraction and "reversal" of flow
positively correlated with inotropic function of the left atrium

Differential diagnosis

While various pathological entities may disturb flow through the pulmonary veins, a series of
predictable changes in the aforementioned waveforms occurs during the progression of diastolic
dysfunction. A progressive increase in left atrial pressure will blunt the systolic flow velocities in the
pulmonary veins, with the majority of forward flow increasingly occurring during diastole. The
elevation in left ventricular end diastolic pressure, secondary to lusitropic incompetence, will
exaggerate the flow reversal that occurs with atrial contraction, prolonging the AR wave 4.

diastolic dysfunction on pulmonary venous Doppler


the S/D ratio
normal filling patterns are predominantly systolic, with an S/D ratio > 1
a pathologic increase in mean left atrial pressure will reverse this pattern, resulting in
an S/D ratio < 1 and a diastolic filling predominance
progressive increase in amplitude of D wave and a decrease in S wave with
increasing filling pressures
atrial reversal velocity and duration
normally the peak of the AR wave is < 35 cm/s
a peak velocity exceeding this upper limit implies elevated filling pressures
the AR wave duration is typically examined in concert with the mitral inflow velocities
the transmitral A wave and the pulmonary venous AR wave should be roughly
similar in length
the duration of the latter should only exceed the former by < 20 m/s, with
greater discrepancies occurring with elevated filling pressures 3
a sensitive indicator of pseudonormalization of the filling pattern (stage III
diastolic dysfunction)
atrial fibrillation on pulmonary venous Doppler
abolition of organized atrial contraction decreases the peak of the S1 wave and decreases
the peak velocity of the AR wave
elevated lusitropy on pulmonary venous Doppler
the enhanced relaxation found in young patients may also reverse the S/D ratio and mimic
advanced diastolic dysfunction
vigorous left ventricular suction results in elevated peak D wave velocities, with a restrictive
transmitral filling pattern
if doubt exists regarding the consequence of these findings, tissue Doppler of the mitral
annulus is required
heart failure with a preserved ejection fraction
vigorous longitudinal excursion of the mitral annulus during systole may obfuscate
increased filling pressures by preserving the (S>D) pulmonary venous systolic filling
dominance
the velocity of the S2 wave is proportionate to the pressure gradient created by this
contraction
however, increased LVEDP imposes an afterload on the left atrium, shortening the duration
of the transmitral A wave while simultaneously prolonging the duration of the pulmonary
AR wave
increasing disparity between the AR duration and the A wave duration correlates with
elevations in filling pressures

References
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URL of Article https://radiopaedia.org/articles/normal-pulmonary-v

Article information
rID: 66714
System: Cardiac
Section: Approach
Tags: cardiology, emergencymedicine, pocus
Synonyms or Alternate Spellings:

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Cases and figures

Case 1: apical 4 chamber viewCase 1: apical 4 chamber view


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Case 2: right upper pulmonary veinCase 2: right upper pulmonary vein


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Case 3: pulmonary venous doppler waveform illustrationCase 3: pulmonary venous doppler waveform
illustration
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