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Review Article
EUROPEAN JOURNAL OF PHARMACEUTICAL
Vartika et al. European Journal of Pharmaceutical and Medical Research
ISSN 2394-3211
AND MEDICAL RESEARCH
www.ejpmr.com EJPMR
ABSTRACT
Strotas are channels which function as medium through which the nutrients, vital resources and biological waste
stream to and fro between the interior, periphery and the exterior of human body. Healthy strotas are the source of
good health. They serve as conduits through the pores of which prasad bhaga (nutrient) and mala bhaga
(metabolic waste) pass to and fro from the poshya or sthayi dhatu (non-circulationg component of tissue). Entire
strotas in body can be summed up as aggregate of gross channels, subtle channels and molecular channels. A brief
discussion regarding origin, appearance, functioning, types and number of different strotas alongwith their
contemporary aspect is made in present study.
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Vartika et al. European Journal of Pharmaceutical and Medical Research
DISCUSSION tract. This helps to keep the lungs free of particles and
The word strotamsi is derived from „Sravnaat strotamsi‟ bacteria as they are highly prone to contagion. Together
which means it is the path that helps in streaming of with blood vessels it also helps to warm and
substances.[4] Strotas are those in which mana (mind), humidify the air before it reaches terminal
prana (vital energy), anna (food nutrients), jala (water), bronchioles.[13] Thus every conduit of transportation or
dhatu (circulating part of dhatu), updhatu (subsidiary strotas is specialised as per the function it has to
tissue product), dhatumala (metabolic waste), mutra perform. On this basis, acharya Charak has given various
(urine), purisha (stool) are moving.[5] The channels synonyms of strotas like sira (vein), dhamani (artery),
which transport the poshaka dhatu (nutrient substances) rasayani (lymphatic ducts), rasavahini (capillary), nadi
are supplied to cells and tissues via the process of (tubular conduits), path (passages), marga (pathways,
transudation through path called as strotas.[6] tracts), sharirchidrani (body orifices),
samvritasamvritani (open or blind passages), sthana
Acharya Charak mentions that person is aggregate of (sites), ashaya (repertories), niketa (resorts).[14] Acharya
strotas because of their pervasiveness and diffusiveness Sushruta does not consider sira and dhamani as strotas
that aggravate and pacify dhatu (tissue). As per Acharya as these are separate entities.
Sushrut- A strotas is tubular structure or organ which
originate from vacant spaces spread throughout the body, Functions of strotas
initiates the flow of the fluid material from the inner of The main functions of strotas are customised as per its
the body to its outer opening.[7] As per Acharya Charak- area of influence. It includes uptake, secretion, recycling
strotas are as large in number as organs are there in our and excretion of waste products. The normal functioning
body. Channels carry the transformed dhatus to different of the particular strotas depends upon its moolasthana.
destinations through their mesh of network to nourish the
cells and tissues.[8] Any injury to the strotas leads to poor Moolasthan as area of influence
circulation resulting in manifestation of disease. Moola is derived from “Moolamiti prabhav sthanam”-
which means root or foundation. The foundation is
Panchabhautik constitution of strotas known as “prabhav sthanam” or area of influence or
While defining panchbhautik predominance of various area of origin. They are basically the controlling organs
body constituents, strotas are enumerated under aakash of strotas. Two chief organs related with the extended
mahabhuta.[9] Entire empty space wherever aakash strotas are defined ultimately for every strotas. These
mahabhuta is present is distributed uniquely. Thus origin moolasthan can be considered as the organ that have
of strotas is by aakash mahabhuta predominantly with significant role in either uptake, secretion, recycling or
other mahabhutas. The cardinal property of aakash excretion of waste products from that strotas.
mahabhuta is apratighat i.e. non- resistance. Non- Moolasthana of srotas can be determined firmly as:
resistance property of strotas is important for supply of Utpatti sthana (origin point of view)
nutrients for apposite growth of the body. Aakash has Sangraha sthana (storage point of view)
only one attribute shabda (sound). Any substance having Vahana sthana (conduction).[15]
quality of tiuch obstructs the movement. Aakash being
devoid of tactile perception doesnot obstruct any As a tree is seriously affected by injury to its root
movement.[10] similarly the channels of circulation in human body are
seriously affected when their moolasthan is injured. The
Swaroop (Appearance of strotas) moolasthan of each abhyantra strotas as per various
Strotas have characteristics similar to dhatu they carry acharyas are explained in table 1.[16,17,18]
and the function they have to perform. They can be
tubular, either large or small, either straight or Any abnormalities in peripheral strotas ultimately can
reticulated.[11] This can be correlated to the specialised affect the moolasthana of Strotas and vice-versa.
type of cells that every organ or organ system have to
carry out specialised function. These specialized cells are Types and Number of strotas
particularly designed to perform the functions for which Acharya Charak used terms sthoola (macro) and anu
they are intended. For instance, neurotransmitters can (micro) for strotas while explaining normal functions of
only be carried via neurons to complete the obligatory vayu as the entity that brings about origin of strotas.[19]
communicative functions. Neurons have extensions These consist of both gross channels (macro) and subtle
called dendrites and axons that bring information into channels (micro) on the basis of morphology. These
and, release information from, the cell itself which is channels of circulation are present in intra-cellular for
unique to them[12]; the mucosa of respiratory channels instance synthesis and formation of cellular structures by
consist of the epithelium and supporting lamina propria. endoplasmic reticulum and golgi apparatus; inter-cellular
The epithelium is made of tall columnar pseudostratified includes transport of lipid soluble substances through
cells having cilia and goblet cells. Mucous from the lipid bilayer and transport of water & lipid insoluble
goblet cells traps particles from the air which are substances through protein channels over cell membrane,
transported upwards towards the pharynx by the cilia on sodium-potassium pump for maintaining ion
the epithelium so as to be expelled out of respiratory concentration across cell membrane; and extra-cellular
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Vartika et al. European Journal of Pharmaceutical and Medical Research
spaces which include secreted protein that remains According to Shalyatantra, piercing of or injury to
associated with the cell as part of the extracellular matrix strotas causes specific pain manifested in certain specific
of the human-body. Hormones, growth factors, cytokines parts of the body. They are important for understanding
and chemokines, various enzymes act by travelling the of the prognosis of such conditions. Thus, Acharya
extracellular space towards biochemical receptors on Charak had explained dushti lakshan of strotas while
cells. Thus entire strotas in body can be summed up as Sushrut had explained viddha lakshan of strotas
aggregate of gross channels, subtle channels and according to surgical aspect.
molecular channels. Gross channels include gastro-
intestinal tracts, respiratory tract, lymphatic systems, Contemporary aspect of strotas
arteries, veins and genito-urinary tracts; subtle channels Different strotas as explained by acharyas have been
include artetioles, venules, capillaries, minute defined in table 2 with their adjacent similitude to organ
lymphatics; molecular channels include permeability of system as per contemporary aspect.[27] The theory of
membranous pores of cell membranes. semi-permeability may be well correlated with transport
via strotas because of their property of being permeable
It is not possible to numerate all strotas as these are to some substances and impermeable to others. [28]
innumerable.[20] Based on location, strotas are classified Likewise particular strotas carries poshaka dhatu
into two categories- bahirmukha strotas (external (nutrients) to its very own poshya dhatu only. The
orifices) and antarmukha strotas (internal structures concept of specific receptors that bind nutrients,
carrying out metabolism). Bahirmukha strotas have their transmitter substances or drugs onto the cell can be
opening to the outside and are seen (externally) with the correlated to selectivity of strotas. This either initiates
naked eye. These are 9 in male and 12 in female. They biological effects or inhibits cellular functions.
include body parts with each having opening for ear-2, A semipermeable membrane is a biological membrane
eyes-2, mouth-1, nostrils-2, anus-1 and urethra-1. In that allows certain molecules or ions to pass through it
female, the additional orifices are 2 openings in the by diffusion, more specialized processes of facilitated
breast and 1 as vaginal orifice. [21] According to diffusion, passive transport or active transport. The rate
Sharangdhar, they are 10 in male and 13 in female- of course depends on the pressure, concentration,
bhramarandhra being extra.[22] Abhyantra strotas on the and temperature of the molecules or solutes on either
other hand are attached to a specific anatomical structure side, as well as the permeability of the membrane to each
called moolasthana. The normal functioning of the solute.[29] This corresponds to selective transport and
particular group of channels is depending upon its transformation of poshaka bhag in particular strotas and
moolasthana. Acharya Charak depicted 13 abhyantra final uptake by poshya bhaga. Permeability may depend
strotas.[23] Acharya Sushruta explained 11 pairs i.e. 22 on solute size, solubility, properties depending on the
strotas called as yogavahi strotas.[24] membrane structure and the solute.
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Vartika et al. European Journal of Pharmaceutical and Medical Research
channel carrying vital nutrients) at that particular site of Samhita. Vol 2. Varanasi. Chowkhamba Sanskrit
strotas which may result in manifestation of disease. The Series Office, 2012; 318,319.
vitiated strotas further vitiates dhatu and this vicious 11. Shastri K., Chaturvedi G., editor. Charak Samhita.
cycle continues. Any vitiation in and around strotas has Vol.1. Varanasi. Chaukhamba Bharti Academy,
to be taken care of judiciously in its early stages. 2011; 714.
12. Gyton A.C., Hall J.E. Textbook of Medical
Ushma of dhatu called as dhatvagni (metabolic enzymes Physiology. Second South Asia edition. Elsevier
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are important for transportation of nutrient and essential Dipika commentary of Chakrapanidatta. Charak
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