APEEJAY STYA UNIVERSITY

A. BASIC INFORMATIONS

1. Course Code \Title\Program: DIPH- / Hospital and Clinical Pharmacy

2. Total Study Hours: 75 hrs. Lecture = 75hrs. (3hrs/ week) Duration: 25 weeks
3. Practical Duration:-3 Hours/week
4. Name and contact details of the instructor:

Name Ms. Poonam Verma

Address Apeejay Stya University, Sohna,

Haryana
Email poonam.verma@asu.apeejay.edu
URL http://university.apeejay.edu/

5. Category : D. Pharm.
6. School : Pharmaceutical Sciences

B. COURSE DESCRIPTION

In this course students will learn about concept of health, disease (types, causative agent, mode
of transmission and prevention). After completing the course, students will understand how can
they serve as a Health Education resource person and community pharmacist for society and can
serve as health care delivery system for all.

C. LEARNING OBJECTIVES

Scope: This course is designed to impart basic knowledge on drug procurement and distribution
to out- patients and in- patients and clinical pharmacy services in the hospital.

Objectives: Upon completion of the course, the student shall be able to understand
Hospital Pharmacy
 To professionalize the functioning of pharmaceutical services in a hospital.
 To contribute to the overall objectives of hospital which is a community centre.
 To ensure the availability of the right medication, at the right time in the right dose, at the
minimum possible cost
 To take upon itself the functions of material management-purchasing, storage, inventory
control and flawless drug distribution system.
 To serve as a counselling department not only to the ultimate user of the drug, but also to
the medical staff and the nursing staff by updating them on dosage regimen, by giving
instructions regarding usage, possible side effects, precautions regarding food etc.

Clinical Pharmacy
 To assist the physician in doing better job of prescribing and monitoring drug therapy.
 To maximise the patients role in the drug use process.
 To assist nurses in administering medications and documenting medication incidents
correctively
 D. Intended Learning Outcomes of Course(ILOs)

After completing this course the student will be able to:

a- Knowledge and Understanding:

1. Understand the elements of pharmaceutical care and provide comprehensive patient care
services
2. Interpret the laboratory results to aid the clinical diagnosis of various disorders
3. Provide integrated, critically analyzed medicine and poison information to enable healthcare
professionals in the efficient patient management
4. Distinguish the different organizations of hospital pharmacy departments , services and
procedures.
5. Deal with pharmaceutical care and the role of the pharmacist in the hospital setting.
b-Intellectual Skills:
After completing this course the student will be able to:
1) Apply their knowledge to prepare parentral infusions for individual patient use.
3) Choose rationally the optimal adjuvant used for delivery of the drug formula.
4) Deal with scientific data and prepare reports to be discussed with instructors.
c-Professional and practical Skills:
After completing this course the student will be able to:
1) Deal with therapeutic regimens for special categories of seriously ill patients.
2) Manage risk issues concerning prevention of the risk of drug – drug interactions and
incompatibilities in pharmaceutical preparations.
3)Use properly the pharmaceutical and medical terms and abbreviations.

d-General and Transferable Skills:

After completing this course the student will be able to:
1) Apply information technology skills to control drug inventories and human resources
management.
2) Have effective verbal and nonverbal communication skills.
3) Acquire a good command of medical terminology which enables him
to deal freely with the medical team.
4) Apply all aspects concerning drugs, purchase, supplies, storage etc. so show decision making
abilities .
5) Command good skills to offer counseling to patients.

E. TEACHING METHODOLOGY

The teacher has plans to lay more emphasis on active participation of every student. Group
discussions and team learning will be encouraged rather than normal lecture based teaching.
Student will be encouraged to ask questions and to participate in cooperative learning
environment of classes. Performance of students will be continuously assessed with the help of
MCQs, quizzes, tests and team projects. Feedback and inputs of students will also be invited at
regular intervals.
 F. COURSE STRUCTURE AND CONTENTS

Unit Unit Title Contents/Learning Domain Teaching Student Number

No methodology Assessment of
Lectures
1 Hospital Pharmacy: http://www.srmu Open book
Introduction to (a) Definition niv.ac.in/sites/de class test
Hospital (b) Functions and objectives of fault/files/downl MCQs
Pharmacy Hospital Pharmaceutical oads/HOSPITAL
services. _PHARMACY.p Class
(c) Location, Layout, Flow df
Assignments 6 lectures
chart of material and men.
(d) Personnel and facilities https://apps.who. Objectives
requirements including int/medicinedocs
equipments based on /documents/s196
individual and basic needs. 22en/s19622en.p
(e) Requirements and abilities df
required for Hospital
pharmacists.
2 Drug http://www.autho Open book
Distribution (a) Out-patient services rstream.com/Pres class test
system in (b) In-patient services-(a) types entation/ARIFA MCQs
Hospitals of services (b) detailed MOMINA-
discussion of unit Dose 1531003-drug- Class 5 Lectures
system, Floor ward stock distribution-
system, Satellite pharmacy Assignments
systems/
services,
Objectives
Central sterile services, Bed
Side Pharmacy.
(a) Economical considerations, http://www.auth Open book
3 Manufacturing: estimation of demand. orstream.com/Pr class test
(b) Sterile manufacture-large esentation/tausif MCQs
and small volume parenterals, 1991-1795419- Class
facilities, requirements, layout design-layout- Assignments
production planning, man- operational- 6 Lectures
Objectives
power requirements. facilities-sterile-
(c) Non-sterile manufacture- products/
Liquid orals, externals-bulk
concentrates. https://www.rese
(d) Procurement of stores and archgate.net/publ
testing of raw materials. ication/2755189
37_A_Review_o
n_Parenteral_Pro
duction_Technol
ogy
Nomenclature Surgical instruments, hospital Open book
4 and uses of :- equipments and health class test
3 lectures
accessories. MCQs
Class
 Assignments
Objectives

Organization, P.T.C (Pharmacy Therapeutic http://www.eahp. Open book

functioning and Committee),Hospital eu/sites/default/fi class test
5 composition Formulary System les/w1_- MCQs
_noemi_martine Class 3 lectures
z_lopez_de_castr Assignments
o.pdf
Objectives
https://www.slid
eshare.net/apollo
james/hospital-
formulary
Drug Responsibility for establishing http://www.autho Open book
6 Information the centre. rstream.com/Pres class test 3 lectures
service and Drug What qualities the Pharmacist entation/siddu83 MCQs
Information has to run the DIS? 90-1377736-dic/ Class
Bulletin. Assignments
http://www.jocpr
Objectives
.com/articles/revi
ew-on-benefits-
of-drug-
information-
services-a-new-
transpiring-
practice-to-
health-care-
professionals-in-
hospitals.pdf
Surgical Surgical dressing like cotton, http://www.authors Open book
7 Dressing and gauze, bandages and adhesive tream.com/Presen class test
tation/ak_shrivasta
Hospital tapes including their va-1760002- MCQs
3 lectures
Supplies pharmacopoeial tests for surgical-products/ Class
quality. Other hospital supply Assignments
e.g I.V sets B.G sets, Ryals https://www.slides
Objectives
tubes, Catheters, Syringes etc. hare.net/Akshatas
hettar/surgical-
aids
Computer https://www.scri Open book
8 Applications in Maintenance of records, bd.com/documen class test
Hospital inventory control, medication t/182852450/Ap MCQs
Pharmacy monitoring, drug information plication-of- 3 lectures
Class
and data storage and retrieval Computers-in- Assignments
in hospital and retail Hospital-and-
pharmacy establishments Objectives
Clinical-
Pharmacy

http://compappin
pharm.blogspot.c
 om/

Part-II : Clinical Definition,scope and concept https://www.rese Open book

9 Pharmacy. of clinical pharmacy. archgate.net/publ class test
3 lectures
Introduction to Constraints on Development of ication/3076660 MCQs
Clinical Clinical Pharmacy 66_Clinical_phar Class
Pharmacy macy_practice_i Assignments
Practice n_developing_co
Objectives
untries_Focus_o
n_India_and_Pa
kistan
10 Modern Pharmacists and Patient https://www.ncbi Open book
dispensing counselling and advice for the .nlm.nih.gov/pm class test
3 lectures
aspects use of common drugs, c/articles/PMC4 MCQs
medication history 211565/ Class
Assignments
http://jprsolution
Objectives
s.info/files/final-
file-
58e05a7d194012
.57689311.pdf
11 Common daily .Introduction, dosage forms of https://pharmlabs Open book
terminology drugs, common .unc.edu/labs/pre class test
3 lectures
used in the Pharmacological glossary, scriptions/latin.ht MCQs
Practice of Pharmaceutical latin terms m Class
Medicine Assignments
Objectives

Pathophysiology . Disease, manifestation and Open book

and symptoms of pathophysiology including class test
12 Diseases salient symptoms to MCQs
understand the disease like Class
Tuberculosis, Hepatitis, Assignments 7 Lectures
Rheumatoid Arthritis,
Objectives
Cardiovascular
diseases, Epilepsy, Diabetes,
Peptic Ulcer, Hypertension.
13 Physiological Haemoglobin values, RBC & https://pdfs.sema Open book
parameters with WBC counts, Differential nticscholar.org/3 class test
5 lectures
their significance count, ESR, Clotting time of 8ed/231835d2e4 MCQs
blood, Urine examination, 825a6ee5543ee2 Class
Heart rate. 6dad16ffb002.pd Assignments
f
Objectives

14 Drug . (a) Definition and http://medind.nic Open book

Interactions: introduction. .in/jav/t15/i1/javt class test
(b) Mechanism of Drug 15i1p42.pdf MCQs
Interaction. Class 7 lectures
 (c) Drug-drug interaction with Assignments
reference to analgesics, http://www.phar Objectives
diuretics, cardiovascular drugs, minfotech.co.nz/
Gastro-intestinal agents, oman/modules/D
Vitamins and Hypoglycemic rug_Interactions.
agents. htm
(d) Drug-food interaction.
15 Adverse Drug https://www.pbm Open book
Reactions: (a) Definition and .va.gov/PBM/va class test
4 lectures
Significance. centerformedicat MCQs
(b) Drug-induced diseases and ionsafety/tools/A Class
Teratogenicity dverseDrugReact Assignments
ion.pdf
Objectives

16 Drugs in Clinical Introduction, general treatment Open book

Toxicity of poisoning, systematic http://iomcworld. class test
antidotes. Treatment of com/ijptp/files/sa MCQs
insecticide poisoning, heavy mbria%20tarlok Class 4 lectures
metal poison, Narcotic %20et%20al Assignments
drugs, Barbiturate, %20dec
Objectives
Organophosphours poisons. %202015.pdf

17 Drug abuse and Introduction, addictive drugs https://www.ther Open book

drug dependence and their treatment, ecoveryvillage.c class test 4 lectures
complications. om/drug- MCQs
addiction/#gref Class
Assignments
Objectives

18 Bioavailability of Introduction, including factors https://www.rese Open book

Drugs affecting it. archgate.net/publ class test 3 lectures
ication/2718328 MCQs
90_Bioavailabilit Class
y_A_Pharmaceut Assignments
ical_Review
Objectives

G. LEARNING RESOURCE MATERIAL

1. Dr. A.R Paradkar, S.A Chunawala, Hospital and Clinical Pharmacy( IInd year D.Pharm),
Twentieth Edition, July 2016, Nirali Prakashan
2. Anees A. Siddiqui, Imran Parvez, Seemi Siddiqui; Text book of Hospital and Clinical
Pharmacy, CBS Publishers.
3. A.V Yadav, B.V Yadav, Hospital and Clinical Pharmacy (IInd Year D.Phram), Fifteenth
Edition, August 2008, Nirali Prakashan.
4. D.J Patil, Hospital and Clinical Pharmacy( IInd year D.Pharm); Second Edition, March
2008, Nirali Prakashan.
5. Remington's Pharmaceutical Sciences.
6. Martindale The Extra Pharmacopoeia

H. LEARNING ASSESSMENT CRITERION

Sessional Exam 2 times during the semester

Sessional I
Sessional II
Duration of Sessional Exams 1 hours each
Marks of each sessional exam Sessional I: 10
Sessional 2: 10
Duration of Final Exam 3 hrs.
Marks of Final Exam 80
Total 100

I. GRADING MATRIX FOR THE COURSE

Score/ Percent Letter Grade

(Indicative^^)
More than 90% A+
85% < 90% A
75% < 85% A-
70% < 75% B+
65% < 70% B
60% < 65% B-
55% < 60% C+
50% < 55% C
< 50% NP

List Of Practical For Hospital & Clinical Pharmacy

A. Preparation of Transfusion Fluids.
P-1. To prepare 100ml of 0.9%w/v sodium chloride injection IP
P-2. To prepare 100ml 0f 5%w/v dextrose injection IP
P-3. To 0.9% w/v sodium chloride and prepare 100ml of 5%w/v of dextrose injection IP
P-4. To prepare 100ml of 10%w/v mannitol intravenous injection IP

B. Sterilization Of Surgical Instruments, Glassware & Other Hospital Supplies

P-5. Sterilization of glassware by hot air oven.
P-6. Sterilization of surgical dressings, glassware etc by autoclave method

C. Evaluation of Surgical Dressings

P-7. Evaluation of given sample of absorbent cotton for loss on drying as per IP norms
P-8. Evaluation of given sample of absorbent cotton for absorbency ( sinking time and
water holding capacity) as per IP 1996 Norms.
P-9. Evaluation of given sample of absorbent cotton for ether soluble substances and water
soluble substances as per IP Norms.
P-10. Evaluation of given sample of absorbent cotton for acidity and alkalinity identification
and surface active substances as per IP 1996 Norms.

D. Handling & Use Of Data Processing Equipments

P-11. Preparation of patients profile for single patient in MS Word
P-12. Preparation of record for registration of patients in hospital using MS Excel sheet.

APEEJAY STYA UNIVERSITY

 A. BASIC INFORMATIONS

1. Course Code \Title\Program: BP-103 Pharmaceutics-I

2. Total Study Hours : 61 hrs. [Lecture = 45 hrs. (3 hrs/week); Self Study, Tutorial = 16
hrs. (1 hr/week)] 61 hrs. Practical
Practical Duration : 4 Hours/week
3. Name and contact details of the instructor:

Name Ms. Poonam Verma

Address Apeejay Stya University, Sohna,

Haryana
Email poonam.verma@asu.apeejay.edu
URL http://university.apeejay.edu/

5. Category : B. Pharm.
6. School : Pharmaceutical Sciences

B. COURSE DESCRIPTION
This course is designed to impart a fundamental knowledge on the preparatory pharmacy
with arts and science of preparing the different conventional dosage forms.
Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new
chemical entity (NCE) into a medication to be used safely and effectively by patients. It is
also called the science of dosage form design. There are many chemicals with
pharmacological properties, but need special measures to help them achieve therapeutically
relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs
to their delivery and disposition in the body. Pharmaceutics deals with the formulation of a
pure drug substance into a dosage form.

C. LEARNING OBJECTIVES

This course will impart basic knowledge in the area of pharmaceutics, various dosage forms and
unit operations involved in pharmaceutical industries. Prescription and its components and
posology are also covered in this course. The objective of this course is to provide the knowledge
to the students with respect to various dosage forms such as powders, monopasic and biphasic
liquid dosage forms, suppositories, pessaries, etc. The students will also get hands-on training in
the preparation of such dosage forms in the laboratory components.

D. LEARNING OUTCOMES

1. Students developed a good knowledge and skills in the development of different

formulations and their evaluation characteristics.
2. Students can understand the formulation, methods of preparation and evaluation of
tablets, capsules and various cosmetic products. Students can also understand the mechanism
of tablet coating.
3. To know various unit operations used in Pharmaceutical industries.
4. To perform various processes involved in pharmaceutical manufacturing process.
5. Solve the problem through the application of fundamental principles of
pharmaceutical metrology and conclude the decision.
 6. Classify different dosage forms and apply principles of pharmaceutical science in
formulation and dispensing the various dosage forms.
7. Apply pharmacopoeial standards for the preparation of various dosage forms.
8. Identify their professional role in the healthcare system.
9. Explain the concept, Formulation, evaluation and packaging of various semisolid dosage
forms
10. Recognize route of drug administration and classification of Pharmaceutical dosage form.
11. Understand various disinfection and sterilization techniques ,evaluate the sterility testing,
microbial assays, pharmacopoeial standards of sterilization process

E. TEACHING METHODOLOGY

The teacher has plans to lay more emphasis on active participation of every student. Group
discussions and team learning will be encouraged rather than normal lecture based teaching.
Student will be encouraged to ask questions and to participate in cooperative learning
environment of classes. Performance of students will be continuously assessed with the help of
MCQs, quizzes, tests and team projects. Feedback and inputs of students will also be invited at
regular intervals.

F. COURSE STRUCTURE AND CONTENTS

Unit Contents Learning Domain Students Number Remarks

No Assessment of
Lectures
Historical background and Open book
development of profession of http://www.cysonline.org/articl class test
pharmacy: History e.asp?issn=2229- MCQs
of profession of Pharmacy in India 5186;year=2010;volume=1;issu
I e=2;spage=7;epage=11;aulast=
in relation to pharmacy education, Class 10
industry Bawa Hours
Assignments
and organization, Pharmacy as a
career, Pharmacopoeias: https://www.researchgate.net/
Objectives
Introduction to IP, BP, publication/321331560_History
USP and Extra Pharmacopoeia. _of_Pharmacy
Dosage forms: Introduction to
dosage forms, classification and https://www.researchgate.net/
definitions publication/44807123_Pharma
cy_Education_in_India
Prescription: Definition, Parts
of prescription, handling of
Prescription and
Errors in prescription.
Posology: Definition, Factors
affecting posology. Pediatric dose
calculations
based on age, body weight and
body surface area.
Pharmaceutical calculations:
Weights and measures – Imperial
& Metric
system, Calculations involving http://www.mediafire.com/file
percentage solutions, alligation, /p4h658n67540l73/Pharmaceu Open book
 proof spirit and tical_Calculations_and_Metrolo class test P-6,
isotonic solutions based on gy.doc/file MCQs P-13
freezing point and molecular
weight. https://www.slideshare.net/Pal Class 10
II laviKurra/lakshmidurga-final-
Powders: Definition, Assignments Hours
classification, advantages and ppt
disadvantages,Simple & Objectives
compound powders – official https://teachntest.files.wordpr
preparations, dusting powders, ess.com/2016/08/pharmaceuti
effervescent, cal-calculations.pdf
efflorescent and hygroscopic
powders, eutectic mixtures.
Geometric dilutions.
Liquid dosage forms:
Advantages and disadvantages of
liquid dosage forms.
Excipients used in formulation of
liquid dosage forms. Solubility
enhancement
techniques
Monophasic liquids: Definitions
and preparations of Gargles, http://www.gputtawar.edu.in/ P-1, P-2,
Mouthwashes, downloads/Monophasic P-3, P-4,
III Open book P-7, P-8
Throat Paint, Eardrops, Nasal %20Liquid%20Dosage
class test P-12,
drops, Enemas, Syrups, Elixirs, %20Forms.pdf
Liniments and MCQs P-15,
Lotions. https://www.slideshare.net/P P-16,
Class P-17,
Biphasic liquids: allaviKurra/pharmaceutical-
Suspensions: Definition, suspensions-and-emulsions Assignments 8 Hours P-18
advantages and disadvantages,
classifications, http://simplepharmanotes.blo Objectives
Preparation of suspensions; gspot.com/2018/01/the-
Flocculated and Deflocculated biphasic-dosage-form-
suspension & stability suspensions.html
problems and methods to
overcome.
Emulsions: Definition,
classification, emulsifying agent,
test for the identification
of type of Emulsion, Methods of
preparation & stability problems
and methods to
overcome.
Suppositories: Definition, types,
IV advantages and disadvantages, https://irjponline.com/admin/p Open book
class test 8 Hours P-14
types of bases, hp/uploads/2515_pdf.pdf
methods of preparations. MCQs
Displacement value & its https://www.researchgate.net/
calculations, evaluation of publication/280105303_Displac Class
suppositories. ement_Value_Calculation_Six_
Assignments
Pharmaceutical Easy_Steps
 incompatibilities: Definition, Objectives
classification, physical, chemical http://www.authorstream.com
and therapeutic incompatibilities /Presentation/kumarawate007-
with examples 2229948-pharmaceutical-
incompatibilities/

https://www.researchgate.net/
publication/332482842_PHAR
MACEUTICAL_INCOMPATIBILITE
S_A_REVIEW
Semisolid dosage forms: https://pdfs.semanticscholar. Open book P-9,
Definitions, classification, org/b0cc/aa16eae4670b9522 class test P-10,
mechanisms and factors 5d8b173deeb53d865dc9.pdf MCQs P-11
influencing dermal penetration of 7 Hours
V drugs. Preparation of ointments, https://www.researchgate.net Class
pastes, creams /publication/320923384_Rec
Assignments
and gels. Excipients used in semi ent_Advances_in_Semisolid
solid dosage forms. Evaluation of _Dosage_Forms Objectives
semi solid
dosages forms
.
Recommended Books: (Latest Editions)

1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott
Williams andWalkins, New Delhi.
2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers,
New Delhi.
3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone,
Edinburgh.
4. Indian pharmacopoeia.
5. British pharmacopoeia.
6. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The
University of Michigan.
7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott
Williams, New Delhi.
8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society,
Elsevier Health Sciences, USA.
10. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC,
New York.
11. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker,
INC, New York.
12. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and
Suspensions, Marcel Dekker, INC, New York

LEARNING ASSESSMENT CRITERION

Sessional Exam 2 times during the semester

Sessional I
 Sessional II
Duration of Sessional Exams 1 hour each
Marks of Sessional exam 15 marks
Continuous mode (Attendance, quiz, presentation
10 marks
etc.)
Duration of End Term Semester Exam 3 hrs.
Marks of End Term Semester Exam 75 marks
Total 100 marks

Scheme for Awarding Internal Assessment: Continuous Mode

Criteria Marks
Attendance 4
Academic activities (Average of any 3 activities e.g. quiz, assignment, open 3
book test, field work, group discussion and seminar)
Student – Teacher interaction 3

LEARNING ASSESSMENT CRITERION PRACTICAL (50 marks)

Duration of Sessional Exams 4 hours
Marks Sessional Exam (2 per semester) 10 marks
Continuous mode (Attendance 2 marks and records
5 marks
3marks, Daily performance etc.)
Duration of End Term Semester Exam 4 hrs.
Marks of End Term Semester Exam 35
Total 50 marks

Question paper pattern for theory Sessional examinations

I. Multiple Choice Questions (MCQs) = 10 x 1 = 10
OR
Objective Type Questions (5 x 2) = 05 x 2 = 10
(Answer all the questions)
I. Long Answers (Answer 1 out of 2) = 1 x 10 = 10
II. Short Answers (Answer 2 out of 3) = 2 x 5 = 10
Total = 30 marks
Question paper pattern for practical sessional examinations
I. Synopsis = 10
II. Experiments = 25
III. Viva voce = 05
Total = 40 marks
Question paper pattern for end semester theory examinations
For 75 marks paper
I. Multiple Choice Questions(MCQs) = 20 x 1 = 20
OR
Objective Type Questions (10 x 2) = 10 x 2 = 20
(Answer all the questions)
II. Long Answers (Answer 2 out of 3) = 2 x 10 = 20
III. Short Answers (Answer 7 out of 9) = 7 x 5 = 35
Total = 75 marks
Question paper pattern for end semester practical examinations
I. Synopsis = 05
II. Experiments = 25
III. Viva voce = 05