Maristela, Iriza III.

About 30 times sweeter than sucrose

A. Only 1 D. II and III
Pole, Rochelle C. B. I and II E. III only
C. I and III
Pharmaceutical Dosage Form and Drug Delivery 11. A hermetic container which permits withdrawal of
System successive portion of the contents without
changing the strength of the remaining portion
1. The purpose of Phase 3 clinical trial is;
A. Multiple dose vial
I. Safety
B. Single dose ampule
II. Effectiveness
C. Blister package
III. Dosage
D. Large plastic bottle for capsule
A. I, II and III D. I and II
E. Tamper-evident package
B. I and III E. I only
12. Photo degradation can be prevented by
C. II and III
packaging drugs in a light resistant container.
2. Which of the following is a correct statement
Which of the following containers is NOT light
regarding TDDS?
resistant?
A. Ortho Evra is a testosterone transdermal
A. Colorless bottle covered with aluminum
system.
foil
B. Skin lotion may be used at the application
B. Bottle covered with carbon paper
site of transdermal patches to avoid irritation.
C. Transparent plastic container
C. Physical exercise and extreme ambient
D. Amber colored bottle
temperature (e.g. sauna) may increase the
E. Opaque plastic container
absorption of drug from Nitroglycerin patch.
13. This plastic material is rigid and has good clarity
D. Absorption of drug from TDDS is greater if
thus, is used in blister packaging of capsules and
the patch is applied to a site with a thick horny
tablets is;
layer.
A. PET D. APET
E. TDDS should be removed when showering,
B. PVC E. APETG
bathing or swimming.
C. PETG
3. Which of the following phrases describe the elixir
14. Simple syrup can be prepared by;
dosage form?
I. Percolation
I. Sweetened and flavored
II. Solution with heat
II. The product contains alcohol as
III. Agitation without heat
preservative
A. I, II and III are correct
III. Medicated or non-medicated
B. I and II are correct
A. I only D. I and II
C. II and III are correct
B. II and III E. I, II and III
D. Only II is correct
C. I and III
E. I and III are correct
4. Which of the following preparations is for external
15. Features of ophthalmic ointment and gels include;
use only?
I. Must be packaged in collapsible
A. Lugol’s solution
ointment tubes having elongated
B. Iodine tincture
narrow tip
C. Magnesium citrate solution
II. Non-sterile preparation
D. Belladonna tincture
III. Ointment bases should have a
E. Diphenhydramine elixir
softening point close to body
5. A preparation applied to the skin with a fine
temperature, both for comfort and for
camel’s hair brush or glass applicator is known
drug release
as:
A. Only 1 D. I and II
A. Glycerite D. cataplasm
B. I and III E. I, II and III
B. Liniment E. glycerogelatin
C. II and III
C. Collodion
16. Ointment base classified as hydrocarbon base
6. For orally administered drug, the dosage form
include;
used as clinical trial material for Phase 1 is;
I. Petrolatum
A. Capsule with excipient
II. White ointment
B. Capsule containing active ingredient alone
III. PEG ointment
C. Tablet without excipient
A. Only 1 D. I and II
D. Tablet with excipient
B. I and III E. I, II and III
E. Solution form
C. II and III
7. If a drug product requires an antioxidant, which of
17. How many percent of glycerin is contained in
the following would be used?
glycerogelatin?
A. Fumed silica D. butylhydroxyanisole
A. 15% D. 5%
B. Titanium dioxide E. Phenylmercuric nitrate
B. 35% E. 10%
C. Benzalkonium chloride
C. 40%
8. The following are physicochemical properties to
18. Papers, Moleskin, linen are types of what
be considered in dosage form design except;
component of plasters?
A. Physical state
A. Adhesives D. Medicaments
B. Nature of the illness
B. Backing material E. Container
C. Polymorphism
C. Absorbent
D. Solubility
19. Creams ointments may be medicated or
E. Dissociation constant
nonmedicated. Which of the following
9. Which of the following excipient are added to
preparations contain a depigmenting
tablet formulation to provide enough bulk for
medicaments?
compression?
A. Crotamiton cream
A. Glidants D. Disintegrants
B. Tolnaftate cream
B. Diluents E. Surfactants
C. Hydroquinone cream
C. Lubricants
D. Mupirocin ointment
10. Characteristics of Stevia powder include;
E. Tetrinoin cream
I. A natural, non-toxic sweetener
II. Contraindicated to phenylketonurics
20. Type of ointment that must meet sterility test and 30. A topical solution employed as astringent was or
requirements for metal particles. wet dressing is;
A. Dermatologic ointment A. Aluminum Subacetate Topical Solution
B. Ophthalmic ointment B. Povidone-Iodine Solution
C. Rectal ointment C. Coal Tar Topical Solution
D. Nasal ointment D. Hydrogen Peroxide Solution
E. Vaginal ointment E. Chlorhexidine Topical Solution
21. An enema used for the diagnostic visualization of 31. Pharmaceutical solutions are of different
the GIT is; characteristics, uses and methods of preparation.
A. Starch enema Which of the following statements correctly
B. Barium sulfate enema describe a specific solution?
C. Aminophylline enema A. Magnesium citrate solution is simple
D. Nutritive enema solution method
E. Hydrocortisone enema B. Liniments are ethereal solutions
22. Nasal preparation are employed; C. Embrocations are used externally and are
I. As nasal decongestant for prevention applied with rubbing
and treatment of allergic rhinitis D. Bactidol is a collyrium
II. To restore moisture and relieve dry, E. Douches are rectal injections
congested and inflamed nasal 32. An aqueous solution used for irrigative cleansing
membranes of the vagina is termed as;
III. In the form of nose drops or sprays A. Enema D. Douche
A. I, II and III D. I and III B. Lavation ori E. Collunarium
B. I and II E. I only C. Embrocation
C. II and III 33. Characteristics of large volume parenterals
23. Flexible Collodion,USP is rendered waterproof by include all of the following EXCEPT;
the addition of; A. Sterile
A. Menthol D. Camphor B. Isotonic
B. Castor oil E. alcohol C. Package in containers not exceeding 1
C. Ether liter
24. Which of the following statements is correct? D. Meet standards for particulate matter
A. Diapid nasal spray is used for the E. Colored
prevention and treatment of perennial 34. The method of sterilization employed for heat-
allergic rhinitis labile enzyme preparations, catheters, needles
B. Lugol’s solution contains sodium iodide as and plastic disposable syringes is;
co-solution A. Sterilization by Ionizing radiation
C. Simple syrup can be prepared by B. Gas sterilization
percolation C. Autoclaving
D. Calcium hydroxide Topical Solution is also D. Steam sterilization
known as Liquor Carbonis Detergens E. Dry heat sterilization
E. Magnesium citrate solution is used as 35. Parenteral preparations are of different types.
antidiarrheal Which of the following is a dry Solid for Injection?
25. This tincture is a topical protectant. A. Propofol, USP
A. Belladonna tincture B. Imipenem and Cilastatin for Injectable
B. Compound benzoin tincture Suspension, USP
C. Tolu balsam tincture C. Methylprednisolone Acetate Suspension,
D. Sweet orange peel tincture USP
E. Iodine tincture D. Insulin Injection, USP
26. Which method is used in the preparation of Ipecac E. Cefuroxime for Injection, USP
Syrup? 36. Pastes are semi-solid preparations that generally
A. Solution with the aid of heat contain a larger portion of solid materials so are;
B. Solution by agitation without the aid of I. Less greasy and stiffer than
heat ointment
C. Solution by chemical reaction II. More macerating and more
D. Percolation penetrating than ointment
E. Any of these III. Are effectively employed to absorb
27. All of the following otic preparations are indicated serous secretions
for bacterial infections of the ear EXCEPT; A. I and II D. III only
A. Auralgan otic Solution B. II and III E. I, II and III
B. Cerumenex Eardrop C. I and III
C. Chloromycetin Otic Solution 37. Considerations in the use of TDDS include;
D. Corticosporin Otic Solution I. Rotating locations within the
E. Maxitrol Drops recommended site should be avoided
28. Aromatic Spirit of Ammonia is a reflex stimulant in the application of replacement
administered; patches
A. Orally II. TDDS should be removed when
B. Topically into the abdomen showering, bathing or swimming
C. By rubbing into the affected area III. Use of the skin lotions should be
D. By inhalation avoided at the application site
E. By subcutaneous injection because they affect skin hydration and
29. A pharmaceutical solvent water intended for the can also alter the partition coefficient
preparation of officially known as; between the drug in the TDDS and the
A. Water, USP skin
B. Purified Water, USP A. I, II and III D. II and III
C. Water for Injection, USP B. I and II E. III only
D. Sterile Water for Injection, USP C. I and III
E. Bacteriostatic Water for Injection, USP 38. All of the following statements are true regarding
biologics, EXCEPT;
 A. Biologic products must pass control C. Stability
requirements such as potency, sterility, 49. Drug substance can be protected from the
pyrogens and constituent materials. destructive influences at atmospheric oxygen or
B. Freezing is required in the storage of humidity through:
biologics. I. Coated tablets
C. Most biologics have an expiration date of II. Enteric coated tablets
a year or longer after the date of III. Sealed ampoules
manufacture. A. I, II and III D. I and III
D. Biologics are generally administered by B. I and II E. III only
injection C. II and III
E. Toxoids and Vaccines are biologics for 50. Preformulation considerations include all of the
active immunity following EXCEPT;
39. Which of the following biologics is available in oral A. Polymorphism
form as enteric coated capsules? B. Stability in the presence of expected
A. Typhoid vaccines excipients
B. Hepatitis B vaccine C. Membrane permeability
C. Diphtheria and Tetanus Toxoids D. Particle size
D. Measles Virus Vaccine E. Dissolution
E. Hepatitis Vaccine 51. Liquid drugs such as Vit A, D and E are
40. Methylcellulose is used in ophthalmic solution as; formulated as;
A. Buffer D. Thickener A. Sublingual tablet
B. Preservative E. Isotonic agent B. Soft gelatin capsule
C. Sterilizing agent C. Nasal inhaler
41. Which of the following preparations is NOT D. Compressed tablets
sterile? E. Hard gelatin capsule
A. Eye drop D. Solution for Injection 52. The original appearance, palatability, uniformity,
B. Implant E. Dialysis Solution dissolution and suspendability are retained. The
C. Suppository type of stability described is;
42. A novel drug delivery system Cyanocobalamin A. Physical D. Microbiologic
(Nascobal Gel) used in the treatment of vitamin B. Chemical E. Therapeutic
B12 deficiency is available as; C. Toxicological
A. A controlled release sublingual application 53. Approaches in the stabilization of drug product
B. Microspheres for injection against hydrolytic decomposition include all of the
C. A nasal gel following EXCEPT;
D. Automatic injector A. Replacement of atmospheric
E. Chewable dispersible tablet B. Supply drug in a dry form for reconstitution
43. Prodrug of biotechnology include all of the C. Refrigeration
following EXCEPT; D. Use of buffering agents
A. Estring D. Rituximab E. Suspending the drug in non-aqueous
B. Interferon E. Epoeitin Alfa vehicle rather than dissolving them in an
C. Human Growth Factor aqueous medium
44. Advair diskuss is a novel preparation for; 54. Based on USP guidelines for extemporaneously
A. Oral inhalation prepared drug products, the stability of water
B. Parenteral administration containing formulation prepared from ingredients
C. Sub gingival application in solid form is;
D. Vaginal inserts A. Not later than 25% of the time remaining
E. Topical delivery until the products expiration date or 6
45. Characteristics of drug substance bet suited for months whichever is earlier.
incorporation into an extended release product B. A beyond use date of 6 months
include; C. A beyond use date not later 14 days on
I. Uniformly absorbed form the GIT storage at cold temperature
II. Possess a good margin of safety D. A beyond use date of the intended
III. Used in the treatment of acute rather duration of therapy or 30 days whichever
than chronic conditions is earlier
A. Only 1 is correct E. None of these
B. I and III are correct 55. TRUE statements regarding flavoring of
C. I and II are correct pharmaceuticals include all of the following
D. I, II and III are correct EXCEPT;
E. Only I is correct A. Fruit or citrus flavors combat acid or sour
46. Camphor is commonly comminuted by which of taste of drugs
the following techniques? B. Children prefer less sweet with tart rather
A. Trituration D. Pulverization by than a fruit flavor pharmaceutical
B. Levigation intervention C. Organic esters, alcohols and aldehydes
C. Sieving E. Micronization are pleasant to taste
47. The vehicle of Effervescent granulated salts D. Chewable tablets and lozenges are
usually contain; usually flavored and sweetened
I. Citric acid E. In selecting a flavorant, the age of the
II. Tartaric acid intended patient must be considered
III. Sodium bicarbonate 56. The following products require the addition of
A. I, II and III D. Only II is correct preservatives EXCEPT;
B. I and III E. I and II A. Syrups D. Ophthalmic products
C. II and III B. Emulsions E. Large volume parenterals
48. Pharmaceutics is concerned with the following C. Semisolid preparations
areas of pharmaceutical dosage form design 57. Strip packs, blister packs, tape seals and bubble
EXCEPT; packs are example of;
A. Formulation D. Sales and marketing A. Light-resistant packaging
B. Manufacture E. Effectiveness B. Compliance packaging
 C. Child-resistant packaging 69. Tablets may differ in terms of release mechanism.
D. Adult-senior use packaging Which of these tablets has delayed-release
58. Characteristics of APET and PETG plastic feature?
materials include; A. Sugar-coated tablets
I. Transparent B. Film-coated tablets
II. Unsuitable for gamma radiation C. Chewable tablets
III. Has excellent luster D. Enteric coated tablets
A. I, II and III D. I and III E. Instant dissolving/disintegrating tablet
B. I and II E. III only 70. Reason for suspension include;
C. II and III I. Sustaining effect
59. Problems encountered with plastic containers II. Taste
include all of the following EXCEPT; III. Stability
A. Permeability A. I, II and III D. III only
B. Alkalinity B. II and III E. I and III
C. Leaching C. I and II
D. Deformation upon storage 71. Characteristics of particle of suspension in ideal
E. Sorption situation include;
60. The following drug products require colorants I. Perfectly spherical in dilute
EXCEPT; suspension
A. Capsules II. No collision of particles
B. Compressed tablets III. Settling of particles obey Stokes’ Law
C. Sugar-coated tablets A. I, II and III D. III only
D. Suppositories B. II and III E. I and III
E. Suspension C. I and II
61. Two plasticized gelatin ribbons are continuously 72. A technique of reducing particle size producing
and simultaneously fed with liquid or pastes fill 10-50um particle diameter is;
between the rollers of the rotary die mechanism. A. Dry milling D. Spray drying
What method of preparing SGC is described? B. Micropulverization E. Fluid energy
A. Plate process D. Punch method C. Micronization grinding
B. Rotary die process E. Both B and C 73. Bentonite, a suspending agent is classified as;
C. Reciprocating die process A. Clay D. Cellulose
62. A tablet excipient that causes adhesion of powder B. Plant colloid E. Protein substance
particles in tablet granulation C. Synthetic
A. Lubricant D. Diluent 74. Caking of particles in suspension can be
B. Disintegrant E. Anti-adherents prevented by including flocculation. Which of the
C. Binder following can be employed as flocculating agent?
63. An excipient used in sugar free-chewable tablet I. Diluted Bentonite magma
A. Mannitol D. lactose II. Surface active agent
B. Sorbitol E. Crystalline maltose III. Electrolytes
C. Xylitol A. I, II and III D. I and II
64. In preparing vaginal inserts, the following B. II and III E. III only
excipients are used EXCEPT; C. I and II
A. Lubricant D. Coating agent 75. These substances increase the viscosity of the
B. Disintegrating agent E. Dispersing agent dispersion medium.
C. Filter A. Wetting agents D. Solubilizing
65. Wecobee bases used in suppositories are agents
triglycerides derived from; B. Flocculating agents E. All of these
A. Mineral oil D. Olive oil C. Suspending agents
B. Coconut oil E. Theobroma oil 76. TRUE statements regarding packaging, labeling
C. Almond oil and storage of suspensions include;
66. In preparing suppositories by molding from a melt, I. Packaged in an oversized container to
lubricating the mold is required if the suppository facilitate through mixing
is; II. A “shake well” label must be affixed
A. PEG-based III. Must be protected from freezing
B. Cocoa butter-based A. I, II and III D. I and II
C. Glycerinated gelatin based B. II and III E. III only
D. Both B and C C. I and III
E. All of these 77. The following are oral suspension EXCEPT;
67. Suppositories using this base should be A. Maalox suspension
moistened first with water to avoid irritation to the B. Combantrin suspension
tissue upon insertion; C. Cesalamine suspension
A. Cocoa-butter D. Amoxicillin suspension
B. Glycerinated gelatin E. Gaviscon Liquid suspension
C. Wecobee base 78. Which of the following properties is undesirable in
D. Glyceryl monopalmitate pharmaceutical suspension?
E. Witepsol base A. Thixotropy D. Bleeding
68. TRUE statement about PEG-bases suppositories B. Caking E. Flocculation
include; C. Cracking
I. Stored at room temperature 79. Single phase gels;
II. Leaks from the orifice I. Are made up of small inorganic
III. It dissolves in the body fluid to release particles
the active drug II. Exhibit Thixotropy
A. I, II and III D. I and II III. Are those in which no apparent
B. I and III E. I only boundaries exist between the
C. II and III dispersed phase and the dispersion
medium
A. I and III D. III only
 B. II and III E. I, II and III 91. A tablet which is 50% larger and heavier than the
C. I and II original uncoated one is;
80. Aluminum hydroxide gel is; A. Sugar-coated tablet
I. Prepared by chemical reaction method B. Film-coated tablet
II. An antacid C. Enteric-coated tablet
III. Applied externally D. Chocolate coated tablet
A. I and II D. III only E. Gelatin coated tablet
B. II and III E. I, II and III 92. Solid dosage administered by oral route include;
C. I and II I. Hypodermic tablets
81. The first step in the continental method of II. Troches
preparing emulsion is the combination of; III. Lollipops
A. Gum and water A. Only I is correct
B. Gum and oil B. II and III are correct
C. Oil and water C. I and II are correct
D. Gum and active ingredient D. I, II and III are correct
E. Gum, water and oil are mixed all together E. I and III are correct
82. Surfactants of HLB value 3 to 6 are employed as; 93. Amount administered to a patient after exposure
A. O/W emulsifier D. Wetting agents or contraction of the illness
B. W/O emulsifier E. Solubilizing agents A. Prophylactic dose
C. Antifoaming agents B. Therapeutic dose
83. This theory of emulsification assumes C. Priming dose
monomolecular layers of emulsifying agent curved D. Maintenance dose
around a droplet of the internal phase. E. Minimum effective concentration
A. Surface tension theory 94. Factors considered in determining a drug’s dose
B. Plastic-film theory during clinical trial include all of the following
C. Oriented-wedge theory EXCEPT;
D. Interfacial film theory A. Age D. Pathologic state
E. Molecular layer theory B. Body weight E. Tolerance
84. Creaming of emulsion through reversible, is not C. Appearance and taste
esthetically acceptable. This problem can be 95. The copies of the NDA submitted by the applicant
remedied by increasing the viscosity of the include;
external phase. Which of the following can I. Field copy
promote the desired condition? II. Pre-approval copy
A. Agitation III. Archival copy
B. Reformulation A. I, II and III D. I and III
C. Addition of suspending agents B. II and III E. III only
D. Addition of preservatives C. I and II
E. Addition of thickeners 96. Clinical trial materials include;
85. The separation of internal phase from the I. The proposed new drug
emulsion is called; II. Placebos
A. Aggregation D. Flocculation III. Comparator drug
B. Creaming E. Sedimentation A. I only D. I and III
C. Breaking B. I and III E. I, II and III
86. Micro emulsion are; C. II and III
I. Thermodynamically stable system 97. A chemical compound that has a fundamental
II. Optically transparent desired biologic or pharmacologic activity is
III. O/W system stabilized by surfactant referred to as;
A. I, II and III D. I and III A. Prodrug D. all of these
B. II and III E. only I B. Lead compound E. none of these
C. I and II C. Goal drug
87. Inhalation aerosols are commonly employed; 98. These are solid dosage forms which are designed
A. As infectives D. in asthma therapy to be inserted under the skin by surgical incision.
B. As contraceptives E. as local anesthetic A. Pellets D. Pills
C. In anorectic conditions B. Inserts E. Troches
88. In mixing powder, the diluent is added in portion C. Plasters
to the potent drug, with trituration after each 99. Cocoa butter, NF is also known as;
addition. What principle is described? A. Yellow wax D. Spermaceti
A. Levigation technique D. Comminution B. Paraffin E. Lanolin
B. Geometric dilution E. Spatulation C. Theobroma oil
C. Pulverization with intervention 100. One of the following is not used in the
89. Powders containing deliquescent and hygroscopic preparation of oral, solution, syrups and elixirs.
materials should be wrapped in what kind of A. Ethylene glycol D. Purified water, USP
paper? B. Alcohol, USP E. Glycerin, USP
I. Vegetable parchment C. Propylene glycol
II. Glassine paper 101. Salicylic acid colloidon contains how many
III. Waxed paper percent of salicylic acid in Flexible Colloidon,
A. I only D. II and III USP?
B. III only E. I, II and III A. 5% D. 15%
C. I and II B. 3% E. 1%
90. In dry or fusion method of preparing effervescent C. 10%
granulated salt, the binding agent used is; 102. Compared with syrups, elixirs are;
A. Alcohol-water mixture I. Less sweet
B. Water of crystallization of citric acid II. Less effective in masking the taste of
C. Alcohol, 95% medicinal substances
D. Lanolin III. More viscous
E. Acacia mucilage A. I, II and III D. II only
B. II and III E. I only
 C. I and II A. Syrup, USP
103. TRUE statements concerning bulk powders; B. Peanut oil
I. oral powders are mixed with water or C. Anise oil
other beverages D. Bacteriostatic water for injection
II. douche powders are dissolve in warm E. White petrolatum
water for vaginal use 113. TRUE statement regarding tartrazine include;
III. dusting powders include topical anti- I. An FD&C color additive
infective, antifungal and antiperspirant II. Can cause hypersensitivity reactions in
A. I, II and III D. II only some individuals
B. I and III E. III only III. Imparts red color to the preparation
C. I and II A. I only D. II and III
104. Blending of powders may be accomplished B. II only E. I, II and III
by; C. I and II
I. Spatulation 114. Type II glass container is;
II. Sifting I. Highly resistant borosilicate
III. Levigation II. Can be used as container for
A. I, II and III D. I and II parenterals
B. I and III E. III only III. Treated soda-lime glass
C. II and III A. I and III D. I and II
105. Different technologies are employed in B. II and III E. I, II and III
preparing modified release products. Glucotrol C. I only
XL, Procardia XL and Covera HS are examples 115. A sugar-based lozenge on a stick (lollipop)
of; used in controlling breakthrough pain in cancer
A. Coated beads/granules patients is;
B. Microencapsulation A. Fentanyl Acti D. Difflam
C. Matrix tablet B. Dormicum E. Alaxan-FR
D. Osmotic tablet hydrocolloid system C. Dequadin
106. F, D and C are used to color; 116. Spansule capsule is;
I. Sugar coated tablets I. An example of extended release
II. Pharmaceutical suspension product prepared by embedding drug
III. Syrups in a slowly eroding hydrophilic matrix
A. III only D. I and III system
B. II and III E. I, II and III II. A capsule containing beads of
C. I and II different coating thickness
107. Advantages of film-coating over sugar-coating III. A half-colored, half-transparent hard
include; gelatin capsule containing colored
I. More durable beads or granules
II. Less bulky A. III only D. I and II
III. Less time consuming to apply B. I and III E. I, II and III
A. I, II and III D. I only C. II and III
B. I and III E. III only 117. The transdermal patch used in travel-related
C. II and III nausea and vomiting that is to be worn in a
108. Characteristics of added substances to hairless area behind the ear is;
capsule formulation; A. Transdermal Nicotine
I. Harmless in quantities used B. Transdermal Clonidine
II. Do not interfere with requisite C. Transdermal Testosterone
compendia assay and tests D. Transdermal Nitroglycerin
III. Do not impair products bioavailability, E. Transdermal Scopolamine
therapeutic efficacy or safety 118. A part of a monolithic transdermal system that
A. I, II and III D. I only functions to store and release the drug at the skin-
B. I and III E. I and II site is the;
C. II and III A. Occlusive backing layer
109. TRUE statements about the function of B. Liquid drug reservoir
excipients used in tablet formulation EXCEPT; C. Semipermeable membrane
A. Binders promote granulation D. Matrix system
B. Glidants promote the flow of the tablet E. Adhesive layer
granulation 119. TRUE statement about vanishing cream
C. Lubricants help the patient to swallow the include;
tablet I. A W/O type of cream
D. Diluents make up the desired bulk of the II. Also known as Petrolatum Rose Water
tablet formulation Ointment
E. Disintegrants promote the breakup of tablets III. Contains large amount of water that
after evaporates after application leaving a
110. The vehicle used in Calamine Lotion is; thin film of stearic acid
A. Aluminum acetate solution A. I, II and III D. I and III
B. Lead acetate solution B. II and III E. III only
C. Calcium hydroxide solution C. I and II
D. Magnesium hydroxide solution 120. Fleet enema is an example of;
E. Purified water, USP A. Diagnostic enema
111. Propofol, USP is a/an; B. Nutritive enema
A. Solution for injection C. Evacuation enema
B. Dry solid for injection D. Non medicated enema
C. Injectable emulsion E. Hydrocortisone enema
D. Injectable suspension 121. Which of the following phrases describe the
E. Not an injectable product elixir dosage form?
112. All of the following are used as vehicle in I. Colloidal dispersion
various dosage forms EXCEPT;
 II. Alcohol and water are its primary B. I and III E. I, II and III
solvents C. II and III
III. The product is self-preserving due to 133. Method used to achieve controlled release
high alcohol content from solid dosage form
A. II only D. I and II I. Coated beads and granules
B. II and III E. I, II and III II. Complex formation
C. I and III III. Ion-exchange resin
122. A colorless to slightly yellow, clear, A. I, II and III D. II and III
effervescent liquid having a sweet, acidulous taste B. I and III E. I only
and a lemon flavor; C. I and II
A. Citric acid syrup 134. Components of glycerogelatin EXCEPT:
B. Magnesium citrate Solution A. Gelatin D. Glycerin
C. Simple syrup B. Petrolatum E. Water
D. Calcium hydroxide solution C. Medicinal agent
E. Aluminum acetate solution 135. Drug dosage form/s that is/are protected from
123. Magnesium aluminum silicate is also known the destructive influence of atmospheric oxygen
as; or humidity.
A. Kaolin D. Bentonite A. Coated tablets D. both a and b
B. Acacia E. Tragacanth B. Sealed ampules E. both a and c
C. Veegum C. Enteric coated
124. Several processes affect the stability and 136. Drug dosage form that are protected from the
pharmaceutical elegance of dispersions. destructive influence of gastric acid after oral
Reversible process include; administration.
I. Caking A. Enteric coated tablets
II. Creaming B. Coated tablets
III. Breaking C. Sealed ampoules
A. I, II and III D. II and III D. Flavored syrups
B. I and II E. II only E. Suspension
C. I and III 137. The amount of heat absorbed when 1 g of a
125. The delivery of fluoride to the teeth may be liquid vaporizes is known as the heat of
accomplish through; vaporization of that liquid and is measured in
A. Sonophoresis D. Ultrasound _______.
B. Phonophoresis E. All of these A. Celsius D. Liter
C. Iontophoresis B. Calories E. Atmosphere
126. The drug antidote for radiation exposure is; C. Grams
A. Cs D. Prussian blue 138. Use to promote and maintain dispersion of
B. Acetazolamide E. Gallium finely subdivided particles of liquid in a vehicle in
C. Captopril which it is immiscible.
127. A radiopharmaceutical used diagnostically to A. Emulsifying agent D. Solvent
evaluate thyroid fraction and morphology. B. Levigating agent E. Humectant
A. Samarium-153 D. Cobalt-57 C. Plasticizer
B. Sodium Iodide-123 E. Stronium- 139. Used as a filtering aid for its adsorbent
89 Chloride qualities.
C. Holmium-166 A. Emulsifying agent D. Solvent
128. This nonradioactive drug is used as an B. Humectants E. Clarifying
alternative to a treadmill stress test prior to agent
cardiac imaging. C. Levigating agent
A. Dipyridamole (Persantine) 140. Used to prevent drying or preparations,
B. Cimetidine (Tagamet) particularly ointments and creams.
C. Captopril (Capoten) A. Levigating agents D. Humectant
D. Furosemide (Lasix) B. Plasticizer E. Solvent
E. Acetazolamide (Diamox) C. Ointment base
129. Inorganic hydrogels; 141. Liquid used as an intervening agent to reduce
I. Single Phase System the particle size of a powder by grinding, usually
II. Bentonite Magma in a mortar.
III. Containing Ingredients dispersing in A. Plasticizer D. Levigating
water agent
A. I and II D. I and III B. Emulsifying agent E. Chelating agent
B. II and III E. I only C. Solvent
C. I, II and III 142. Used to impart color to liquid and solid
130. Upward creaming takes place in unstable preparations.
emulsion in which the internal phase has a _____ A. Flavorant D. Solvent
density that the external phase. B. Colorant E. Humectant
A. Lesser D. Minimal C. Clarifying agent
B. Greater E. Exceedingly high 143. Used in tablet and capsule formulations to
C. Equal improve flow properties of the powder mixture.
131. Which of the following can exhibit a reversible A. Tablet lubricant
sol-to-gel or gel-to-sol transformation? B. Tablet glidant
A. Gels D. Mixture C. Tablet disintegrant
B. Magmas E. both A and B D. Tablet opaquant
C. Lotions E. Tablet polishing agent
132. Membrane-controlled transdermal system 144. Used in tablet formulation to reduce friction
contains the following layers; during tablet compression.
I. An occlusive backing layer A. Tablet lubricant
II. Drug matrix system B. Tablet glidant
III. Micro porous rate-limiting membrane C. Tablet disintegrant
A. III only D. I and II D. Tablet opaquant
 E. Tablet polishing agent 156. Which statement is not true or rectal route of
145. Which of the following given is consider as administration?
example of a tonicity agent? A. used for local effect
A. Sodium chloride D. Liquid glucose B. used for systemic effect
B. Mineral oil E. Hydroxyl cellulose C. preferred for drugs that are destroyed or
C. Sodium glycolate inactivated by the environments of the stomach and
146. It describe the passage of (drug) molecule intestines.
through a membrane that does not actively D. 100% of drug absorbed bypass the liver
participate in the process. E. inconvenient
A. Drug absorption D. Osmosis
157. Which statement is not true in parental route
B. Transport mechanism E.
of drug administration?
Dissociation
C. Passive diffusion A. rapid absorption
147. The rate and extent to which an active drug B. little is lost
ingredient or therapeutic moiety is absorbed from C. for uncooperative unconscious patients
a drug product and becomes available at the site D. once injected, withdrawal of drug is easy
of action. E. sterile
A. Drugs solubility 158. Semisolid that have greater aesthetic appeal
B. Adsorption for their non greasy character, ability to varnish into
C. Peak concentration the skin upon rubbing and ability to absorb serous
D. Bioavailability discharges from the skin lesions.
E. Serum concentration time A. pastes D. powder
148. Drug products that contain the identical B. lotions E. ointment
therapeutic moiety or its precursor but not C. creams
necessarily in the same amount or dosage form 159. Semisolid that contain more solid materials,
as the same salt or ester. stiffer and less penetrating, preferred when
A. Pharmaceutical alternatives protective action is desired.
B. Pharmaceutical equivalents A. ointments D. suspension
C. Bioequivalence drug product B. pastes E. lotion
D. Therapeutic equivalent C. creams
E. Bioavailability
160. Dosage form of choice if increased spread
149. Drug products that contain identical amounts
ability over large areas of skin is desired.
of the identical active drug ingredients, that is, the
A. cream D. pastes
same salt or ester of the same therapeutic moiety
in identical dosage forms but not necessarily B. ointment E. powder
containing the same inactive ingredients. C. lotion
A. Pharmaceutical alternatives 161. Characteristics of ophthalmic preparation,
B. Pharmaceutical equivalents EXCEPT
C. Bioequivalence drug product A. sterile
D. Therapeutic equivalent B. free of grit
E. Bioavailability C. usually absorbed in great extent
150. Drug substance physiochemical properties D. solution, ointment and suspension form may be
that influence bioavailability of oral drugs. employed
A. Particle size D. Liquid solubility E. none of the above
B. Salt form E. All of the above 162. Site of excretion of volatile drugs
C. Hydration A. kidney D. saliva
B. sweat glands E. Lacrimal fluids
151. Pharmaceutical ingredients that influence C. lungs
bioavailability of oral drugs. 163. Example of drug that enter breast milk and
A. Fillers D. Lubricants may be passed on to nursing infants EXCEPT
B. Binders E. All of the above A. theophylline D. diltiazem
C. Coatings B. reserpine E. none of the above
152. Characteristics of dosage forms that influence C. barbiturates
the bioavailability of oral drugs. 164. Method for the determination of particle size
A. Disintegration rate D. Storage condition A. sieving D. light scattering
B. Dissolution rate E. All of the above B. microscopy E. all of the above
C. Product age C. sedimentation rate
153. Physiologic factors that influence the 165. Solid dosage forms in which medicinal agents
bioavailability of oral drugs. and/or inert substances are enclosed in a small
A. Gastric emptying time D. Pathologic shell of gelatin.
condition A. Capsules D. suppositories
B. Intestinal transit time E. All of the above B. tablets E. coated tablet
C. Gastrointestinal abnormality C. pills
154. Site of sublingual route of administration 166. It is obtained by the partial hydrolysis of
A. Rectal collagen obtained from the skin, white connective
D. Under the tongue tissue, and bones of animals.
B. Heart A. agar D. albumin
E. Spine B. gelatin E. dye
C. Bone C. talc
155. A coronary vasodilator used in prophylaxis 167. Capsule size available for human use
and treatment of angina pectoris, which dissolves A. 00 D. 3
under the tongue. B. 1 E. all of the above
A. Aspirin D. Phenytoin C. 2
B. Aspilet E. Warfarin 168. Temperatures that thermally bond the
C. Nitroglycerin capsules’ cap and body.
A. 15 C-20 C D. 30 C-35 C 181. The ideal molecular weight of a drug for
B. 20 C-25 C E. 40 C-45 C transdermal drug delivery is
C. 25 C-30 C A. 1000 and below D. 400 and below
169. Preservative used for soft gelatin capsules B. 800 and below E. none of the above
A. glycerin D. 80% ethyl alcohol C. 600 and below
B. sorbitol E. 95% ethyl alcohol 182. Advantages of transdermal drug delivery
C. methylparaben systems EXCEPT
170. Compressed tablets coated with a thin layer of A. it can avoid gastrointestinal drug absorption
a polymer capable of forming a skin like film. difficulties
A. sugar coated D. enteric coated B. it avoid first pass effect
B. film coated E. buccal tablet C. they are nonvasive
C. gelatin coated D. only potent drugs are suitable candidates for
171. Tablet which have a smooth rapid transdermal delivery
disintegration when chewed or allowed to dissolved E. they are easily and rapidly identified in
in the mouth have a creamy base, usually of emergencies
specially flavored and colored mannitol. 183. The first transdermal system for hypertension
A. sugar coated tablet D. chewable tablet A. nicotine D. estradiol
B. enteric coated tablet E. sublingual B. clonidine E. nifedipine
tablet C. nitroglycerin
C. buccal tablet 184. General guidelines for TDDS’s EXCEPT
172. Prepared by compressing granular A. it should be apply to clean, dry skin
effervescent salts that release gas when in contact B. under of skin lotion should be avoided at the
with water. application site
A. Molded tablet D. Effervescent tablet C. it can be physically altered by cutting
B. Tablet triturates E. Dispensing tablet D. it may be left on when showering, bathing, or
C. Hypodermic tablet swimming
173. Used to determine the tablet’s durability E. it should be applied with thoroughly clean hands
A. Hardness tester D. Microprocessor 185. Suppositories that are shaped like a bullet, or
B. Friability E. Tablet dissolution torpedo or the little finger
C. disintegration testing apparatus A. rectal D. nasal
174. Described dosage forms having drug release B. vaginal E. aural
features based on time, course and/or location that C. urethral
are designed to accomplish therapeutic or 186. Suppositories that are usually globular,
convenience objectives not offered conventional or oviform, or cone-shaped and weighed about 5g
immediate release form. when cocoa butter is the base.
A. extended release D. repeat action A. rectal D. nasal
B. modified release E. target release B. vaginal E. aural
C. delayed release C. urethral
175. Dosage form that allows a reduction in dosing 187. Solid dosage forms that are intended for
frequency from that necessitated by a conventional insertion into the body orifices where they melt,
dosage form, such as solution or an immediate soften or dissolve and exert local or systemic
release dosage form. effects.
A. Modified release D. repeat action A. suppositories D. emulsion
B. Extended release E. target release B. tablets E. lozenges
C. Delayed release C. pills
176. Dosage form designed to release the drug at a 188.The most frequently employed suppository
time other than promptly after administration bases.
A. Modified release D. repeat action A. water miscible bases D. glycerin
B. Extended release E. target release B. polyethylene glycols E. polyoxyl 40
C. Delayed release stearate
177. Drug release directed toward isolating or C. fatty bases
concentrating a drug in a body region, tissue, or 189. Type of suppositories that are thinner and
site of absorption or for drug action. tapered, often about 5mm in diameter.
A. Modified release D. target action A. rectal D. nasal
B. Extended release E. repeat release B. urethral E. aural
C. Delayed release C. vaginal
178. Absorption bases obtained from the wool of 190. Example of rectal suppositories
sheep, is a purified wax like substance that has A. clindamycin phosphate
been cleaned, deodorize, and decolorized. B. clotrimazole
A. petrolatum D. yellow ointment C. miconazole nitrate
B. lanolin E. none of the above D. nonoxynol-9
C. white ointment E. bisacodyl
179. Package for ointments and other semisolid 191. Example of vaginal suppositories
preparations. A. bisacodyl D. hydromorphone
A. large mouth jars D. well closed container B. chlorpromazine E. clotrimazole
B. metal tubes E. all of the above C. hydrocortisone
C. plastic tubes 192. A viscous liquid, miscible with water and
180. Plastic masses containing gelatin (15%), alcohol, frequently substituted for glycerin in
glycerin (40%), water (35%) and medical substance modern pharmaceutical formulations.
(10%). A. isopropyl alcohol D. glycerol
A. gels D. glycerogelatins B. purified water E. tap water
B. pastes E. gelatins C. propylene glycol
C. plasters
193. Purified water, USP, is obtained by the E. all of the above
following EXCEPT 206. The withdrawal of desired constituents from
A. distillation D. all of the crude drugs through the use of selected solvents in
above which the desired constituents are soluble.
B. ion exchange treatment E. none of the above A. distillation D. mixing
C. reverse osmosis B. extraction E. trituration
194. Processes referred to in the industry as cross- C. osmosis
flow membrane filtration. 207. Concentrated preparations of vegetable or
A. ion exchange method D. anion exchange animal drugs obtained by removal of the active
B. reverse osmosis E. distillation method constituents of the respective drug with suitable
C. cation exchange menstrual
195. Methods of expressing the strengths of A. percolates D. fluidextracts
pharmaceutical preparation EXCEPT B. macerate E. solvents
A. %w/v D. ration of strength C. extracts
B. %w/w E. ratio of strength 208. Process in which a comminuted dug is
C. %w/w extracted of its soluble constituents by the slow
196. A normal physiologic body response to rid passage of a suitable solvent through the column of
itself of a noxious or toxic substance, such as a drug.
rotavirus or Escherichia coli. A. extraction D. percolation
A. diarrhea D. hypovolemic shock B. digestion E. infusion
B. vomiting E. fever C. maceration
C. acidosis 209. It is a process in which the properly
197. Concentrated aqueous preparations of a sugar comminuted drug is permitted to soak in the
or sugar substitute with or without flavoring agents menstruum until the cellular structure is softened
and medicinal substances. and penetrated by the menstruum and the soluble
A. syrups D. magma constituents are dissolved.
B. elixir E. juice A. infusion D. percolation
C. solutions B. maceration E. extraction
198. Clear, sweetened hydro alcoholic solutions C. decoction
intended for oral use and are usually flavored to 210. Preparations containing finely divided drug
enhance their palatability. particles distributed uniformly throughout a vehicle
A. syrups D. juice in which the drug exhibits a minimum degree of
B. elixir E. magma solubility.
C. solutions A. magma D. suspension
199. Self preserving elixir and do not require the B. tinctures E. gel
addition of an antimicrobial agent. C. emulsions
A. 2%-4% alcohol D. 8%-10% alcohol 211. Reason/s for preparing suspensions EXCEPT
B. 4%-6% alcohol E. 10%-12% alcohol A. drugs are chemically unstable in solution
C. 6%-8% alcohol B. ease of swallowing
200. Alcoholic or hydro alcoholic solutions prepared C. used to prepare a palatable liquid dosage form
from vegetable materials or from chemical D. flexible in administration of a range of doses
substances. E. none of the above
A. elixir D. solution 212. The study of flow which addresses the
B. syrup E. juice viscosity characteristics of powders, fluids and
C. tinctures semisolids.
201. Water-soluble organic mercurial antibacterial A. stokes
agent used topically for its bacteriostatic and mild B. colligative properties
fungi static properties. C. embryology
A. hydrogen peroxide topical solution D. rheology
B. Povidone iodine topical solution E. embryology
C. chlorhexidine gluconate 213. Guidelines in packaging and storage of
D. thimerosal topical solution suspensions EXCEPT
E. none of the above A. use wide mouth container
202. Component/s of douche powders EXCEPT B. adequate airspace above the liquid
A. boric acid D. sodium citrate C. tight container
B. zinc sulfate E. none of the above D. clear bottle
C. detergents E. protected from freezing
203. Component/s of douche powder 214. A dispersion in which the disperse phase is
A. boric acid D. sodium chloride composed of small globules of a liquid distributed
B. alum E. all of the above throughout s vehicle in which it is immiscible.
C. menthol A. suspension D. emulsion
204. Medicinal substances employed topically in B. magma E. tincture
the mouth EXCEPT C. gel
A. benzocaine eugenol D. 215. In emulsion terminology, the dispersed phase
parachlorphenol is the
B. sodium fluoride E. none of the above A. external phase D. all of the above
C. carbamide peroxide B. internal phase E. none of the above
205. Medical substances employed topically in the C. continuous phase
mouth. 216. Phases of emulsion EXCEPT
A. benzocaine A. dispersed phase D. external phase
B. camphorated parachlorophenol B. dispersion medium E. none of the above
C. carbamide peroxide C. emulsifying agent
D. lidocaine
217. Continental method of emulsion preparation is A. stem D. mounting cup
also referred as B. gasket E. housing
A. dry gum method D. all of the above C. spring
B. 4:2:1 E. a & b only 230. Part of the usual aerosol that holds the gasket
C. English method in place and is the mechanism by which the
218. Method which is useful for the actuator retracts when pressure is released,
extemporaneous preparation of emulsions from returning the valve to the closed position.
volatile oils or oleaginous substances of low A. stem D. mounting cup
viscosities. B. gasket E. housing
A. Forbes bottle method C. spring
B. English method D. auxiliary method 231. Part of the usual aerosol valve assembly that
C. dry gum method E. wet gum method is attached to the aerosol can or container and hold
219. Semisolid systems consisting of dispersion the valve in place.
made up of either small inorganic particles or large A. actuator D. mounting cup
organic molecules enclosing and interpenetrated by B. stem E. spring
a liquid. C. gasket
A. suspension D. collodion 232. Part of the usual aerosol valve assembly
B. gels E. ointment which extends from the housing down into the
C. emulsion product and brings the formulation from the
220. The taking up a certain amount of liquid container to the valve.
without a measurable increase in volume. A. stem D. spring
A. imbibition D. thixotropy B. dip tube E. actuator
B. swelling E. xerogel C. gasket
C. syneresis 233. Part of the usual aerosol valve assembly
221. Taking up a liquid by a gel with an increase in which are made of plastic EXCEPT
volume A. actuator D. mounting cup
A. imbibition D. thixotropy B. housing E. dip tube
B. swelling E. xerogel C. stem
C. syneresis 234. Temperature necessary to liquefy the
222. It occurs when the interaction between propellant gas in aerosol
particles of the dispersed phase becomes so great A. 0 C and below D. -15 C to -20 C
that on standing, the dispersing medium is B. -10 C to -15 C E. -20 to -25 C
squeezed out in droplets and the gel shrinks. C. -34 C to -40 C
A. imbibition D. thixotropy 235. Sterile, pyrogen limited preparations intended
B. swelling E. xerogel to be administered parentally
C. syneresis A. aerosols D. all of the above
223. A reversible gel sol with no change in volume B. injections E. none of the above
or temperature. C. ophthalmic solution
A. imbibition D. thixotropy 236. Small amount of powder may be blended by
B. swelling E. xerogel the movement of a pharmaceutical spatula thru the
C. syneresis powders on a sheet of paper or pill tile
224. It is formed when the liquid is removed from a A. Spatulation D. Tumbling
gel and only the framework remains B. Trituration E. all of the above
A. imbibition D. thixotropy C. Sifting
B. swelling E. xerogel 237. Very fine powders intended for the different
C. syneresis body cavity such as ears, nose, throats, teeth and
225. Example/s of gelling agent vagina.
A. acacia D. ethylcellulose A. Douche powder D. Teas
B. alginic acid E. all of the above B. Dusting powder E. Inhalations
C. bentonite C. Insufflations
226. Pressurized dosage forms that upon actuation 238. Study of particles
emit a fine dispersion of liquid and/or solid A. Micromeritics D. Micromintics
materials containing one or more active ingredients B. Micromerics E. none of the above
in a gaseous medium. C. Micrometics
A. magma D. aerosol 239. A thin semi-opaque paper having limited
B. gel E. inhalant moisture resistant qualities.
C. inhalation A. simple white bond paper
227. Components of an aerosol formulation B. Vegetable parchment
A. product concentrate C. Glassine
B. propellant D. Waxed
C. active ingredient 240. Tablets that are prepared by compressing
D. all of the above granular effervescent salts or other materials
E. none of the above having the capacity to release gas (CO2) when in
228. Liquified gas propellants used in aerosol contact with water.
products which are being phased out A. Effervescent tablet
A. dichlorodifluoromethane B. Press coated tablet
B. difluoroethane C. layered tablets
C. chlorofluorocarbon D. Enteric coated tablets
D. chlorofluorocarbon E. multiple compressed tablets
E. dichlorotetrafluoroethane 241. Tablets prepared by compressing tablets to a
229. Part of the usual aerosol valve assembly that special tablet machine and compressing another
supports the actuator and delivers the formulation layer around the performed tablet.
in the proper from to the chamber of the actuator. A. press coated tablet
B. layered tablets 252. Plastic masses intended for topical application
C. melt-in-your mouth tablets containing gelatin, glycerin, water and added
D. multiple compressed tablets medicinal materials.
E. enteric coated tablets A. glycerogelatin D. plasters
242. Defined as solid dosage forms in which one or B. gelatin E. none of the above
more medication and/or inert substances are C. TDDS
enclosed within a small shell or container of a 253. Common topical dusting powder to prevent
suitable form of gelatin. irritation and chafing.
A. capsule D. caplet A. Tolnaftate powder
B. Tablet E. both A and B B. Chloride powder
C. powder C. Plain talcum powder
243. Disc shaped, solid dosage form containing a D. Nystatin powder
medicinal agent and flavoring agent, intended to be E. all of the above
slowly dissolved in the oral cavity or mouth for local 254. Fabrics and/or film even coated on one side
effect. with a pressure sensitive adhesive mixture.
A. Lozenges D. Caplet A. petrolatum gauze D. adhesive bandage
B. Troches E. both A and B B. absorbent gauze E. gauze
C. Pills C. adhesive tapes
244. Sterile solutions that are compounded and 255. Contains 1% of liquefied phenol in calamine
package for instillation into the eyes. lotion
A. Opthalmic solutions A. phenolated calamine lotion
B. Ear preparations B. white lotion
C. Eye drops C. sulfur lotion
D. Nasal preparations D. calamine lotion
E. Opthalmic ointments E. all of the above
245. Preservative mixture which is effective against 256. It is a process of comminution in which a paste
some strains of Pseudomonas aeruginosa, an is formed by combining the powder material and a
organism that can invade an abraded cornea and small amount of liquid in which the powder is
cause ulceration and blindness. insoluble.
A. Polymixin B, Benzothonium chloride A. Levigation D. Sifting
B. Benzalkonium chloride, Thimerosal B. Trituration E. all of the above
C. Benzalkonium chloride, Polyxmyxin B C. Spatulation
D. Phenyl mercuric nitrate, Chlorobutanol 257. Powders containing deliquescent and
E. Polymixin B and sodium benzoate hygroscopic materials should be wrapped in what
246. Opthalmic preparation which is used to kind of paper.
increase the corneal contact time of a drug A. Vegetable parchment D. Waxed paper
substance and thus provide a more sustained B. Glassine paper E. colored paper
action. C. Bond paper
A. opthalmic suspension 258. This type of coating imparts the same general
B. opthalmic ointment characteristics as sugar coating with the added
C. opthalmic drops advantage of a greatly reduced time period
D. opthalmic solution required for the coating preparation.
E. otic suspension A. enteric coating
247. Chloromycetin 1% Opthalmic ointment B. film coating
A. SAilver nitrate opthal solution C. multiple layer coating
B. Pilocarpine HCl Opthal solution D. single layer coating
C. Chloramphenicol Opthal ointment E. none of the above
D. Naphazoline Opthalmic solution 259. This is a method of preparing tablets in which
E. Polymixin B Opthalmic solution the powder mixture is compacted in large pieces
248. Preparations usually placed in the ear canal and subsequently broken down or sized into
by drops or in small amounts to remove excessive granules.
cerumen, treat ear infection, pain and inflammation. A. wet granulation D. slugging
A. aural preparation D. ophthalmic preparation B. dry granulation E. compactness
B. ear preparation E. both A and B C. direct compression
C. nasal preparation 260. For some granular chemicals like potassium
249. Most common preservative used in opthalmic chloride, this method of preparation of tablet is an
preparations. advantage to use.
A. Benzalkonium chloride D. both A and C A. wet granulation
B. Thimerosal E. all of the above B. dry granulation D. Geometric dilution
C. Chlorobutanol C. direct compression E. slugging
250. Tinactin solution 261. This substance provides water solubility or
A. Tolnaftate permeability to the film to ensure penetration by
B. Povidone Iodine D. Calcium hydroxide body fluids and therapeutic availability of the drug.
C. Carbol-fuschin E. Thimerosal A. alloying substance D. glossant
251. Liquid preparations composed of pyroxylin B. plasticizer E. none of the above
dissolve in a solvent mixture equally composed of C. film former
alcohol and ether with or without added medicinal 262. Problem often encountered in film coating
substances. process characterized by roughness of the tablet
A. Glycerogelatin D. Plaster surface due to failure of spray droplets to coalesce.
B. Sponge E. Paste A. Peeling D. Bridging
C. Collodion B. Picking E. none of the above
C. Orange peel effect
263. Corresponds to the filling-in of the score line or 275. The amount of preservative required to protect
intended logo on the tablet by the film. against microbial growth varies with the proportion
A. Peeling D. Mottling of water available for growth. What is the usual
B. Picking E. none of the above effective concentration of benzoic acid as
C. Bridging preservative?
264. Most common wall forming material used in A. 1% D. 0.01-0.02%
microencapsulation. B. 1-2% E. 0.001-0.002%
A. Lactose D. Dextrose C. 0.1-0.2%
B. Gelatin E. none of the above 276. Relative sweetness of aspartame when
C. Sorbitol compared to sucrose is
265. The following ointment base/s is/are classified A. 1:1 D. 300:1
as hydrocarbon base/s: B. 30:1 E. 500:1
A. Petrolatum USP D. both A and B C.180:1
B. White ointment E. both A and C 277. Tinctures of potent drugs for which no
C. Polyethylene glycol ointment proportion has been fixed, shall have the strength
266. Polyethylene glycol is an example of of:
A. Hydrocarbon base A. 10% by weight D. 50% by weight
B. Water removable base B. 20% by weight E. 60% by weight
C. Absorption base C. 40% by weight
D. Water soluble base 278. Peppermint spirit USP is prepared by:
E. All of these A. solution with maceration
267. Petrolatum USP is: B. chemical reaction
A. a purified mixture of semi-solid hydrocarbons C. Distillation
from petroleum that has been wholly or nearly D. Fermentation
decolorized E. none of the above
B. also known as Yellow ointment 279. Flexible collodion is prepared by adding castor
C. also known as White ointment oil and camphor to collodion. How many % of
D. water soluble castor oil is required in this preparation?
E. none of the above A. 3% D. 0.5%
268. Hydrophilic petrolatum USP is classified as: B. 5% E. 0.005%
A. Hydrocarbon base C. 2%
B. Oleaginous base 280. Salicylic acid contains how many percentage
C. Absorption base of salicylic acid in Flexible collodion?
D. Water removable base A. 3% D. 15%
E. all of the above B. 5% E. 20%
269. Semi-solid preparations containing one or C. 10%
more medicinal agents dissolved or dispersed in 281. Gylcerin or glycerites contain ____ of glycerin
either an oil-in-water emulsion or in another type of A. 50% D. 1%
water washable base. B. 25% E. 0.5%
A. creams D. Ointments C. 10%
B. Gel E. all of the above 282. These are concentrated preparations of
C. Paste vegetable or animal drugs obtained by the removal
270. How many percent of glycerin is contained in a of the active constituents of the respective drugs
glycerogelatin preparation? with suitable menstrual and evaporation of all or
A. 15% D. 5% nearly all the solvent.
B. 35% E. 10% A. Fluidextract
C. 40% B. Distillate
271. This type of suppository base includes C. Extractive
mixtures of fatty and water soluble bases. Example D. Extraction
is Polyoxyl 40 stearate E. none of these
A. fatty base 283. This method of extraction is a process in
B. water miscible base which the soluble constituents of a comminuted
C. water soluble base drug is extracted by the slow passage of a suitable
D. miscellaneous base solvent through a column of the drug.
E. None of the above A. Percoaltion D. Maceration
272. Glyceryl monopalmitate is an example of this B. Infusion E. Steam distillation
type of suppository base C. Decoction
A. fatty base 284. These preparations are made so that each mL
B. water miscible base contains the therapeutic constituents of 1 g of the
C. water soluble base standard drug that it presents.
D. absorption base A. Fluid extract D. Infusate
E. greaseless B. Macerate E. Extract
273. The most frequently employed method in the C. Extractive
preparation of suppositories both on small scale 285. Coarse dispersion include:
and on industrial scale is: A. Emulsion D. all of the above
A. Molding D. Hand shaping B. Gel E. none of the above
B. compression E. none of the above C. Magma
C. Hand rolling 286. In emulsion terminology, the dispersed phase
274. Water impurifies like calcium and magnesium is referred to as:
can be removed by: A. Internal phase D. Dispersion medium
A. Ion exchange D. distillation B. External phase E. Both B and C
B. Absorption E. all of the above C. Continuous phase
C. filtration
287. If the oleaginous phase is the internal phase, B. hydroxyl ethylene diphosphonate
then the emulsion is referred to as: C. radiopharmacy
A. o/w emulsion D. w/o/w emulsion D. radiation
B. o/w/o emulsion E. none of the above E. none of the above
C. w/o emulsion 300. Radiopharmaceutical drugs that are used for
288. This emulsifying agent has a disadvantage of the treatment of non Hodgkin lymphoma
producing emulsions that are too fluid and which A. Bexxar D. Prosta scint
becomes more fluid upon standing. B. Ceretec E. myoview
A. Gelatin D. Bentonite C. Choletec
B. Casein E. none of the above
C. Egg yolk
289. In a small scale extemporaneous preparation
of emulsion, this/these method/s may be applied:
A. Dry gum method D. all of the above
B. wet gum method E. none of the above
C. Forbes method
290. These are thermodynamically stable, optically
transparent, isotropic mixtures of a biphasic oil-
water system stabilized with surfactants.
A. Microemulsion D. o/w emulsion
B. Auxilliary emulsion E. w/o emulsion
C. w/o/w emulsion
291. Mineral Oil emulsion is a/an:
A. o/w emulsion D. w/o/w emulsion
B. o/w/o emulsion E. none of the above
C. w/o emulsion
292. This is used for preparing fluidextracts with
boiling water as the menstruum, alcohol being
added as a preservative to the concentrated
percolate.
A. Process A D. Process E
B. Process B E. Process M
C. Process D
293. This is a percolation method that can be
modified for fluidextracts that must be assayed.
A. Process A D. Process E
B. Process B E. Process M
C. Process C
294. Magnesium aluminum silicate, also known as
veegum, in concentrations of _____, forms firm,
thixotropic gels.
A. 10% D. 1%
B. 5% E. 0.5%
C. 2%
295. Bentonite magma is a preparation of ___
bentonite a native colloidal hydrates aluminum
silicate in purified water.
A. 10% D. 1%
B. 5% E. 0.5%
C. 2%
296. In moist heat sterilization, spores of which
microorganisms are most commonly employed?
A. Bacillus stearothermophilus
B. Bacillus subtilis
C. Bacillus pumilus
D. Clostridium botulinum
E. none of the above
297. A rectal preparation for therapeutic,
diagnostic, or nutritive purposes.
A. Enema D. Suppositories
B. Elixir E. Foam
C. Collodion
298. A solid or semisolid mass supplied on a
backing material and intended to provide prolonged
contact with the skin.
A. Patch D. Foam
B. Plaster E. Gum
C. Film
299. It has been employed to study cerebral
physiology and a rapidly growing non invasive
modality for the diagnosis and management of
cancer.
A. positron emission tomography