Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
DOI 10.1007/s00167-011-1610-1
KNEE
Received: 8 February 2011 / Accepted: 4 July 2011 / Published online: 20 July 2011
Ó Springer-Verlag 2011
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572 Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578
shift of the tibiofemoral contact area. Rodner et al. [18] performed in seven knees and with anterior cruciate liga-
advocate that the increased posterior tibial slope in anterior ment reconstruction in two knees. The clinical diagnosis of
cruciate ligament-deficient knees treated with open-wedge osteoarthritis of the knee was made based on American
HTO redistributes pressure into the posterior tibial plateau, College of Rheumatology criteria [3]. Rosenberg radiog-
and suggest that the undesired redistribution of contact raphy (45° flexion posteroanterior weight bearing) was
pressure may increase the rate of degeneration and used to evaluate osteoarthritis [19]. Spontaneous osteone-
disability. crosis of the knee was diagnosed using magnetic resonance
We hypothesized that increase in the posterior tibial imaging (MRI) [24, 25]. The exclusion criteria consisted of
slope can result in correction loss in the frontal plane. In a genu valgus deformity, previous knee surgery, and
this study, therefore, we observed the characteristic ana- rheumatoid arthritis. There were no complications such as
tomical features of virtual osteotomy surface by computed intra-articular fracture, compartment syndrome, peroneal
tomography (CT), and the posterior tibial slope and the nerve palsy, infection, and nonunion.
hip–knee–ankle angle were accurately measured based on
CT data. Furthermore, we compared two surgical methods. Surgical technique
To our knowledge, the correlation between the changes of
posterior tibial slope and the degrees of correction angle is The knees were divided into the following two groups by
unknown. The purpose of this study was to clarify the surgical methods. In the time period between 2006 and
causes of the increase in posterior tibial slope. In addition, 2008, all osteotomies were fixed with VS Osteotomy Plate
we investigated whether the changes of posterior tibial [Biomet, Parsippany, US] (n = 13, Group A). Between
slope in sagittal plane influenced the correction angle in 2008 and 2009, all osteotomies were fixed with second-
frontal plane. generation interlocking Puddu plate [Arthrex, Naples, US]
and staples [Meira, Nagoya, Japan] (n = 13, Group B).
Medial incision below the joint line was performed to
Materials and methods expose the medial tibial head. The anserinus pes was
incised by an electrocautery. In fluoroscopy, a K-wire was
All patients agreed to participate in the study. The patient introduced along the oblique osteotomy line as orientation,
consent procedure strictly involved disclosure, under- from the region 3 cm below the medial joint line to the top
standing, and voluntariness. The study protocol was noted of fibular head. Osteotomy was carried out by an oscillating
to accord with a criterion of the Institutional Review Board saw parallel to the K-wire. The proximal tibia was osteo-
in the Kinki University Hospital that the approval of the tomized by wide chisels with leaving 5 mm of the lateral
committee is not needed. We reviewed 20 patients (26 cortex. The osteotomy surface was opened carefully by
knees) treated with open-wedge HTO between 2006 and triangle chisels with avoiding intra-articular fracture.
2009 (Table 1). The patients were 10 men and 10 women In Group A, the opening gap was fixed with VS Oste-
at mean age of 42.8 ± 14.0 years (range, 22–65 years). otomy Plate having the trapezoidal block with a 2° pos-
There were 11 right and 15 left knees; six cases were terior slope in order to adjust to the cutting edge of tibia.
bilateral. Based on the inclusion criteria, 19 knees of The VS osteotomy plate was mounted in the anteromedial
medial osteoarthritis with varus deformity and seven of aspect of the proximal tibia (Fig. 1). The mean gap value of
spontaneous osteonecrosis of medial compartment with the used plate was 8.4 ± 2.3 mm (range: 5–12.5).
varus malalignment were enrolled. The procedure com- In Group B, the staples and the interlocking Puddu plate
bined with mosaic plasty for cartilage treatment was were used, and anterior and posterior opening gaps were
Table 1 Characteristics of
Variables period Group A (n = 13) 2006–2008 Group B (n = 13) 2008–2009
subjects
Implant VS osteotomy systemÒ (Dynafix) Opening wedge plate systemÒ
(Arthrex) ? staple
The gap value of the used plate 8.4 ± 2.3 mm (5.0–12.5) 8.2 ± 1.8 mm (5.0–10.0)
mean, SD, (range)
Age (mean/range) 45.1/22–65 39.2/23–58
Patients/joints (no.) 11/13 9/13
Diagnosis (no. of joint)
Osteoarthritis 7 12
Osteonecrosis 6 1
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Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578 573
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574 Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578
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Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578 575
15
Group A Group A
* Group B
**
* Group B
*
** p=0.02
*
13.3
5.2 5.5
11.2 11.4 11.7 5
3.6 3.9
**
0
2.1 -1.5 -1.6
0.3 *p<0.0001
** N.S.
-5
Before After Difference
Before After Difference
Fig. 4 The hip–knee–ankle angle in Groups A (open square) and B
Fig. 3 The posterior tibial slope in Groups A (open square) and B (filled square). Left column hip–knee–ankle angle before operation,
(filled square). Left column posterior tibial slope before operation, Middle column hip–knee–ankle angle after operation, Right column
Middle column posterior tibial slope after operation, Right column difference between the hip–knee–ankle angle before and after
difference between the posterior tibial slope before and after operation. (*P \ 0.0001, ** not significant)
operation. For each box and whiskers plot, the top and bottom
borders of the box represent the 25th and 75th percentiles, respec-
tively, and the cross (?) in the box is the mean. The ends of whiskers
represent the minimum and maximum of all the data. (*not : Group A : Group B
significant, **P = 0.02)
The correction rate (%)
Results
from that after operation in both the groups (n.s.). Further, y = -4.6047x + 94.426
the difference in posterior tibial slope before operation
from that after operation was 2.1 ± 2.5° (range:
-2.7–6.1°) in Group A and 0.2 ± 1.2° (range: -1.8–1.7°) Difference of posterior tibial slope (degree)
in Group B, which showed a statistically significant dif-
ference between the groups (P = 0.02). Fig. 5 Scatter plots of the difference between the tibial posterior
slope before and after operation plotted against the correction rate in
After operation, mean hip–knee–ankle angle significantly
all knees (open circle: Group A, filled circle: Group B). A line of the
increased from 3.6 ± 3.2° (range: 0–11.5°) of varus to -1.5 ± best fit constructed by regression analysis is shown. In the Pearson’s
1.7° (range: -3.9–1.0°) of varus (P \ 0.0001) in Group A, correlation test, the correction rate was significantly correlated with
and from 3.9 ± 2.0° (range: 0.3–6.9°) of varus to -1.6 ± the changes of posterior tibial slope after operation (R = -0.55,
P = 0.003, y = -4.6047x ? 94.426)
1.2° (range: -4–0.4°) of varus in Group B (P \ 0.0001)
(Fig. 4). The difference between the hip–knee–ankle angles
before and after operation was 5.2 ± 2.3° (range: 2.8–11.8°) angle at operation was 6.1 ± 2.2° (range: 3.4–11.2°) in
in Group A and 5.5 ± 2.3° (range: 2.1–9.3°) in Group B, Group A and 6.1 ± 2.2° (range: 3.4–8.6°) in Group B,
suggesting there was no significant difference between the which showed no significant difference between the groups
groups (n.s.). (n.s.). The correction rate was 85.4 ± 18.6% (range:
The obtained correction angle in the frontal plane was 57.6–120.1%) in Group A and 93.0 ± 14.6% (range:
defined as the differences between the hip–knee–ankle 76.8–118.1%) in Group B, suggesting no significant dif-
angles before and after operation. The desired correction ference between the groups (n.s.).
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576 Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578
The correction rate was statistically correlated with the tibial slope after operation (data not shown). In Group B,
difference between the posterior tibial slope before and after the anterior and posterior opening gaps were fixed sepa-
operation in all knees (R = -0.55, P = 0.003, Fig. 5). rately to achieve the preoperatively planed values calcu-
lated based on each patient’s CT data, and the posterior
tibial slope was well maintained after operation. Therefore,
Discussion it was thought to be necessary that the anterior gap and
posterior gap were fixed separately to maintain the pos-
The most important finding of the present study was to terior tibial slope.
clarify the causes of the increase in the posterior tibial It was important to select the appropriate location of the
slope. It is necessary to achieve precisely the desired cor- spacer block plate for avoiding the correction loss and for
rection during open-wedge HTO. the increase in posterior tibial slope. The location where
Numerous studies have reported increase (approxi- the plate could be placed was the anteromedial cortex of
mately 2°–4°) in the posterior tibial slope after open-wedge proximal tibia (Fig. 2 shows the location from Points A to
HTO [5, 8, 15, 17]. Undesired changes in the posterior B). Hernigou et al. [10] report that the bone wedges should
tibial slope may influence knee kinematics and stability [9, be grafted in the most posterior region of the opened
15, 18]. Some methods to maintain the original posterior osteotomy site to avoid correction loss and to increase the
tibial slope after open-wedge HTO have been developed. posterior slope. However, if a desired gap is located not in
Noyes et al. [17] suggest that the posterior slope may the most medial point (Point B), but in the most posterior
increase if the anterior opening gap at the tibial tuberosity point (Point C), the correction loss cannot be prevented. VS
is equal to the posteromedial gap. In addition, the anterior osteotomy system plate (Group A) could not be placed in
opening gap should be about half of the posteromedial gap the region sufficiently close to the most medial point due to
to maintain the posterior slope. According to Song et al. its wide profile, and a spacer block of this plate would be
[20], the anterior gap at anteromedial cortex should be placed apart from the most medial point. Interlocking
fixed to be approximately 67% of the posterior gap at the Puddu spacer plate (Group B) having narrow profile could
posteromedial corner of proximal tibia using CT naviga- be placed in the region close to the most medial point. Our
tion. According to Jacobi et al. [13], the two reference results showed that the correction rate was not significantly
K-wires is placed at the proximal and distal to the osteot- different between Groups A and B. However, the correc-
omy of the tibia, and two K-wire should be kept parallel to tion loss would appear when the location of the spacer plate
ensure maintenance of the original tibial slope during the separated from the most medial point.
procedure [12, 13]. Marti et al. [15] suggest that incom- Although the correction rate was not statistically different
plete osteotomy of the posterior cortex and inadequate between the groups, it was correlated with changes in the
release of the posterior soft tissue aiming at avoiding the posterior tibial slope. This indicated there was a trade-off
risk of neurovascular injury may increase the posterior relationship between the correction in the frontal plane and
tibial slope. that in the sagittal plane. Wang et al. [23] report that oste-
It is important to open the osteotomy surface symmet- otomy of the proximal tibia using the lateral location as a
rically in order to maintain the posterior tibial slope after cortical hinge during open-wedge HTO affects the changes
medial open-wedge HTO. In other words, the osteotomy of posterior tibial slope less than that using the posterolateral
surface should be opened in an ‘‘open-book’’ fashion in the location as a cortical hinge. However, they cannot find the
frontal plane, but not in the sagittal plane. The osteotomy correlation between the correction angle and the posterior
surface showed the characteristic anatomical features slope. In the present study, it seemed that shifting the location
(Fig. 2). Theoretically, if Point B (the most medial point) of cortical hinge from the lateral to the posterolateral regions
was opened to the level of a desired gap in an open-book led to the increase in posterior tibial slope. Therefore, the
fashion using Point D (the most lateral point) as a hinge, increase in posterior tibial slope might result in correction
the posterior tibial slope angle might not be changed. In loss in the frontal plane.
Group A, the opening gap was fixed with VS osteotomy The present study had several limitations. First, the
plate having a 2° posterior slope in order to adjust the number of subjects was small. The posterior tibial slope
cutting edge of tibia, but the mean increase in posterior measured using a conventional radiographic technique
tibial slope was approximately 2.1°. The plate having a shows variations depending on rotations of the tibia in the
trapezoidal block with an only 2° posterior slope was not lateral view [8, 14]. Therefore, to secure the accuracy of
able to sufficiently decrease the changes of posterior tibial each measurement, CT scan was used. Although we had
slope after open-wedge HTO. When a 10-mm gap was informed the patients of the deleterious effects of radiation
opened at operation, approximately 5° posterior slope were exposure, radiation exposure by scan could provide various
necessary in a trapezoidal block to maintain the posterior harmful effects. Thus, we do not perform CT scan recently
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Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578 577
for preoperative planning or postoperative assessment. Conflict of interest All authors do not have any financial support
Second, to fix anterior and posterior gaps separately, a and any competing interest with regard to this manuscript.
staple and the interlocking Puddu plate were used in this
case series. If open-wedge HTO was performed with the
implants that do not have spacer blocks (e.g., Tomofix References
Plate, Synthes, Tokyo, Japan), the anterior and posterior
1. Aglietti P, Rinonapoli E et al (1983) Tibial osteotomy for the
gaps can be set independently, the correction loss would varus osteoarthritic knee. Clin Orthop Relat Res 176:239–251
not appear consequently [22]. Third, CT scan for postop- 2. Agneskirchner JD, Hurschler C et al (2004) Effect of high tibial
erative assessment was obtained a month after operation. flexion osteotomy on cartilage pressure and joint kinematics: a
El-Azab et al. [8] report that changes in the posterior tibial biomechanical study in human cadaveric knees. Arch Orthop
Trauma Surg 124:575–584
slope after open-wedge HTO become stable over time, by 3. Altman R, Asch E et al (1986) Development of criteria for the
comparing the changes immediately after operation and classification and reporting of osteoarthritis. Classification of
those at the time of implant removal. Therefore, we thought osteoarthritis of the knee. Diagnostic and Therapeutic Criteria
that the condition a month after operation would have been Committee of the American Rheumatism Association. Arthritis
Rheum 29(8):1039–1049
maintained since then, and correction loss might not occur. 4. Bauer GC, Insall J et al (1969) Tibial osteotomy in gonarthro-
Forth, substantial differences in the amount of medial sis (osteo-arthritis of the knee). J Bone Joint Surg Am
opening between the patients may significantly influence 51(8):1545–1563
the measured data of the posterior tibial slope. To dem- 5. Brouwer RW, Bierma-Zeinstra SM et al (2005) Patellar height
and the inclination of the tibial plateau after high tibial osteot-
onstrate that the correction rate affects changes in the omy. The open versus the closed-wedge technique. J Bone Joint
slope, we should measure the slope in patients with the Surg Br 87(9):1227–1232
same amount of medial opening. In this study, however, 6. Coventry MB, Ilstrup DM et al (1993) Proximal tibial osteotomy.
the gap value of the used plate varied from 5.0 to 12.5 mm A critical long-term study of eighty-seven cases. J Bone Joint
Surg Am 75(2):196–201
depending on the individuals, while about 76% of all cases 7. Debeyre J, Frain P (1967) An intercondylar femoral osteotomy
ranged from 7.5 to 10.0 mm. The small range of distribu- technique in the management of knee deviations due to arthrosis.
tion seems to lead our conclusion that the correction rate Ann Chir 21:548–553
affects changes in the slope. In the strict sense, it is nec- 8. El-Azab H, Halawa A et al (2008) The effect of closed- and open-
wedge high tibial osteotomy on tibial slope: a retrospective
essary to make further studies using cases with the plate of radiological review of 120 cases. J Bone Joint Surg Br
an equal gap. 90(9):1193–1197
Increase in posterior tibial slope would result in 9. Giffin JR, Vogrin TM et al (2004) Effects of increasing tibial
correction loss. Our findings may help us resolve the slope on the biomechanics of the knee. Am J Sports Med
32(2):376–382
uncertainties regarding to the correction loss in medial 10. Hernigou P, Medevielle D et al (1987) Proximal tibial osteotomy
open-wedge HTO. for osteoarthritis with varus deformity: a ten to thirteen-year
follow up study. J Bone Joint Surg Am 69(3):332–354
11. Hernigou P (2002) Open wedge tibial osteotomy: combined
coronal and sagittal correction. Knee 9(1):15–20
Conclusions 12. Hinterwimmer S, Beitzel K et al (2011) Control of posterior tibial
slope and patellar height in open-wedge valgus high tibial oste-
The trapezoidal block of plate having an only 2° posterior otomy. Am J Sports Med 39(4):851–856
13. Jacobi M, Wahl P et al (2010) Avoiding intraoperative compli-
slope could not sufficiently decrease changes of the pos- cations in open-wedge high tibial valgus osteotomy: technical
terior tibial slope. Therefore, it was necessary to fix the advancement. Knee Surg Sports Traumatol Arthrosc 18(2):
anterior and posterior gaps separately. The security of 200–203
correction angle had a trade-off relationship with the 14. Kessler MA, Burkart A et al (2003) Development of a
3-dimensional method to determine the tibial slope with multi-
changes of posterior tibial slope after open-wedge HTO. slice-CT. Z Orthop Ihre Grenzgeb 141:143–147
Therefore, the increase in posterior tibial slope might result 15. Marti CB, Gautier E et al (2004) Accuracy of frontal and sagittal
in correction loss in the frontal plane. It was required to plane correction in open-wedge high tibial osteotomy. Arthros-
understand the characteristic anatomical features of oste- copy 20(4):366–372
16. Miller BS, Downie B et al (2009) Complications after medial
otomy surface and to pay special attentions to the fixation opening wedge high tibial osteotomy. Arthroscopy 25(6):
of opening gap during open-wedge HTO. 639–646
17. Noyes FR, Goebel SX et al (2005) Opening wedge tibial oste-
Ethical board review statement All patients agreed to participate otomy: the 3-triangle method to correct tibial alignment and tibial
in the study. The patient consent procedure strictly involved disclo- slope. Am J Sports Med 33:378–387
sure, understanding, and voluntariness. The study protocol was noted 18. Rodner CM, Adams DJ et al (2006) Medial opening wedge tibial
to accord with a criterion of the Institutional Review Board in the osteotomy and the sagittal plane: the effect of increasing tibial
Kinki University Hospital that the approval of the committee is not slope on tibiofemoral contact pressure. Am J Sports Med
needed. 34(9):1431–1441
123
578 Knee Surg Sports Traumatol Arthrosc (2012) 20:571–578
19. Rosenberg TD, Paulos LE et al (1988) The forty-five-degree 23. Wang JH, Bae JH et al (2009) Medial open wedge high tibial
posteroanterior flexion weight-bearing radiograph of the knee. osteotomy: the effect of the cortical hinge on posterior tibial
J Bone Joint Surg Am 70(10):1479–1483 slope. Am J Sports Med 37(12):2411–2418
20. Song EK, Seon JK et al (2007) How to avoid unintended increase 24. Yamamoto T, Bullough PG (2000) Spontaneous osteonecrosis of
of posterior slope in navigation-assisted open-wedge high tibial the knee: the result of subchondral insufficiency fracture. J Bone
osteotomy. Orthopedics 30(10 Suppl):S127–S131 Joint Surg Am 82(6):858–866
21. Spahn G (2004) Complications in high tibial (medial opening 25. Yates PJ, Calder JD et al (2007) Early MRI diagnosis and non-
wedge) osteotomy. Arch Orthop Trauma Surg 124(10):649–653 surgical management of spontaneous osteonecrosis of the knee.
22. Staubli AE, De Simoni C et al (2003) TomoFix: a new LCP- Knee 14(2):112–116
concept for open wedge osteotomy of the medial proximal tibia–
early results in 92 cases. Injury 34(Suppl 2):B55–B62
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