Software Data Analysis LIOFeron® TB/LTBI Vs.

Diagnosis

LIOFeron® Clinical sensitivity and specificity : LIOFeron® TB / LTBI

Stand-Alone Software A total of 294 known samples
Tuberculosis IGRA Assay
SPECIFICITY: 97.61 %
✓ Import Data
✓ Results within minutes SENSITIVITY: 97.67 %

LIOFERON® TB/LTBI Concordance:

VS. DIAGNOSIS

No of
Information Sample + - Samples
LIOFERON® Analysis Software
positive
(TB + LTBI) 42 41 43 97,67%
Version 1.0 Build 0.5)
CompanyName LIONEX GmbH negative
Copyright Christoph Lorenz Consulting 2018 (HIV, NTM 6 245 251 97,61%
+ healthy)

LIOFeron® TB/LTBI Vs. reference IGRA method Soon available

>95% concordance for negative &

positive samples. Developped by LIONEX Germany

LIOSpot® TB
Reference IGRA kit
METHOD
positive negative

LIOFeron® negative 2 84
TB/LTBI positive 48 1 ELISPOT Kit for active tuberculosis
Covered by 20 years dedicated to the development of faster and more
Total results: 50 85
LIONEX INTERNATIONAL PATENTS specific tests for tuberculosis diagnosis based on patented
% Concordance 96.00 98.82 processes & technologies.

bioactiva@bioactiva.de · www.bioactiva.de bioactiva@bioactiva.de · www.bioactiva.de bioactiva@bioactiva.de · www.bioactiva.de

 LIOFeron® TB/LTBI a two component IGRA Kit LIOFeron® TB/LTBI a two component IGRA Kit

Transfer 1 mL of human
blood sample
Human blood stimulation tubes: 4 Tubes (Li-Heparin) into each tube LIOFeron®TB/LTBI - HUMAN IFN-γ ELISA
• Tube TB A contains antigens known to be
missing in BCG and commonly used widely
for IGRA tests (green cap)

• Tube TB B contains a proprietary of Lionex

antigen of CD8+ epitopes (blue cap)

• Positive control (ready-to-use) contains

Li-Heparin and mitogen (black cap)

• Negative control (ready-to-use) contains

Li-Heparin (white cap)

INCUBATION DURATION:
16-24 h at 37°C

Remove
human
plasma

Supernatant
(human plasma)

Red blood Human plasma ready

cells for quantification
of IFN-y levels by
HUMAN IFN-y ELISA

bioactiva@bioactiva.de · www.bioactiva.de bioactiva@bioactiva.de · www.bioactiva.de bioactiva@bioactiva.de · www.bioactiva.de