FULLY AUTOMATED PHENOTYPIC AST SYSTEM

TM dRASTTM

dRAST Gram positive & negative panels

dRAST in 6 hours Rapid AST
TM
GP/GN panels for positive blood culture

on PBC
The timely and optimal antibiotic treatment is essential for saving lives of patients with serious infections and for Gram Positive
reducing the use of broad-spectrum antibiotics in antibiotic resistance era.
Antimicrobial agent Concentration (µg/ml) Staphylococcus spp. Enterococcus spp.
dRAST™ performs rapid antimicrobial susceptibility testing directly from positive blood cultures, enabling early
Ampicillin 0.25, 2, 4, 8
stage optimal targeted treatment with the speed that no one ever provided. Ciprofloxacin 0.12, 1, 2
Clindamycin 0.03, 0.25, 0.5, 1, 2
dRAST™ reports optimal antibiotics with MIC(Minimum Inhibitory Concentration) after 6 hours from positive Erythromycin 0.5, 1, 2, 4
blood culture, while other conventional systems take 2-3 days. Gentamicin 1, 2, 4, 8, 16
Levofloxacin 0.12, 1, 2
Linezolid 0.5, 2, 4
dRAST™ from PBC Oxacillin 0.06, 0.25, 0.5, 1, 2

dRASTTM Save 2 days Penicillin 0.12, 0.25, 0.5, 1, 2, 4, 8

Blood Culture Rifampin 0.06, 0.12, 0.25, 0.5, 1, 2, 4
AST
Tetracycline 1, 2, 4, 8, 32
Tirimethoprim/Sulfamethoxazole 0.5/9.5, 2/38, 4/76
Conventional AST
Vancomycin 0.5, 2, 4, 8, 16
Cefoxitin screen 0.5, 4, 8
Blood Culture Pure culture Conventional AST
Gentamicin high level 128, 256, 500
0 Day 1 Day 2 Day 3 Day Streptomycin high level 512, 1000
Inducible Clindamycin resistance 0.5/4

Gram Negative
Burkholderia Other
Antimicrobial agent Concentration (µg/ml) Enterobacteriaceae P. aeruginosa Acinetobacter spp. cepacia complex S. maltophilia Non-Enterobacteriaceae
580
680 Amikacin 0.5, 4, 8, 16, 32
FAST RANDOM ACCESS
Amoxicillin/Clavulanate 2/1, 8/4, 16/8
Direct rapid AST platform Random access function with Ampicillin 1, 8, 16
report optimal antibiotics with emergency samples Ampicillin/Sulbactam 1/0.5, 8/4, 16/8
MIC after 6 hours from PBC Aztreonam 1, 2, 4, 8, 16
Cefazolin 0.5, 2, 4
Cefepime 0.25, 1, 2, 4, 8, 16
Cefotaxime 1, 2, 4, 8, 16, 32
Ceftazidime 0.5, 1, 2, 4, 8, 16
Ciprofloxacin 0.06, 0.12, 0.25, 0.5, 1, 2
SIMPLE FLEXIBLE
Colistin 0.12, 3
Minimal hands on time to operate 1060 Easy to add new antibiotics
Ertapenem 0.5, 1, 8
Stand alone with embedded PC due to technology principle
Gentamicin 0.25, 2, 4, 8
Imipenem 0.5, 1, 2, 4, 8
Meropenem 0.12, 1, 2, 4, 8
Minocycline 0.12, 1, 4, 8
Piperacillin/Tazobactam 4/4, 8/4, 16/4, 32/4, 64/4
Trimethoprim/Sulfamethoxazole 0.5/9.5, 2/38, 4/76
DIRECT LIS ESBL
No sub culture for AST Reliable and efficient integration
No McFarland for inoculum of LIS

Ref: MKT-BDRA1EN A
QuantaMatrix Korea QuantaMatrix Europe
16F, 17F, Bldg.B, BYC HIGHCITY, 131, Villejuif Bio Park - 1 Mail du Pr Georges Mathé
Gasan digital 1-ro, Geumcheon-gu, 94800 Villejuif - France
www.quantamatrix.com Seoul, Rep. of KOREA contact-europe@quantamatrix.com
dRAST TECHNOLOGIES

dRAST Kit TM
Fully automated incubating, imaging, analysis
Single bacterial cells under
GP/GN panels / Gel / Broth
with 2 random access capability
various antimicrobial conditions 1 Panels 2 Gel
Ready to use consumable
Automated dispenser for sample, agarose and growth media

in microfluidic channel GP/GN panels for positive blood culture Agarose for immobilizing bacteria
Microscopic optics to observe cell growth via time-lapse imaging
Temperature control system for incubation
Patented micro-patterned 96 wells with dried
A positive blood culture is mixed with agarose to immobilize
17 GP / 19 GN antibiotics
bacteria cells for microscopic imaging.
Dried antibiotics are rehydrated by adding culture medium.
Automated microscopic imaging is used to detect bacterial growth.

Image processing and analysis software

3 Broth Reporting susceptibility results by proprietary algorithm and database
Automated image processing for growth measurement
Growth medium & pipette tips
Imaging each well every hour MIC determination and SIR interpretation based on data base and expert rules
Reliable and efficient integration of LIS
We can determine MIC and SIR for antimicrobial while observing bacterial growth in real time using a patented
microfluidic chip. Sample + Agarose

Time-lapse tracking for bacterial growth

Robust and accurate image processing alogorithm
Dried antibiotics
Media

You just work on the table 1 minute

Result report
Resistant
Automatic MIC determination and
Susceptible SIR interpretation

1h 2h 3h 4h 5h 6h Scan sample Load cartridge Load Panel