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The journal Chest, the official publication of the American College of Chest
Physicians, highlighted in its review earlier this year that exposure to fine
particulate matter (PM) 2.5 or less is the fifth leading risk factor for death in
the world.
In the recent Global Burden of Disease data analysis as well, more than one
million premature deaths were attributable to ambient air pollution in 2015 in
India. Your lungs, heart and the brain are worst sufferers when pollution
levels peak as very fine PM particles can find their way into the circulatory
system and damage the organs.
“When we say PM 2.5 or 10, it is only the size of the particle we are talking
about and the kind of damage afflicted depends on the source of these
particles, such as firecrackers, fuel combustion, stubble burning, etc. PM
formed due to diesel or kerosene burning can cause lung cancer,” says Dr GC
Khilnani, former head of pulmonology department, All India Institute of
Medical Sciences (AIIMS).
The damage starts with inflammation of the airway, and finer the particulate
matter the deeper it penetrates. “What nobody talks much about but who do
the maximum damage are ultrafine particles of 0.1 micron or less. These
penetrate the lungs and reach the blood stream. Once they are in your blood,
these can go anywhere – the brain, the heart, kidneys, etc.,” said Dr Khilnani,
“When these fine particles that lungs aren’t able to filter reach the blood
stream, these get attached to the blood vessel walls – the arteries. Over a
period of time, there can be a clot formation inside the vessel that can lead to
blockage. There can be a sudden narrowing of the blood vessels that can
eventually lead to a heart attack,” said Dr Upendra Kaul, senior cardiologist,
Batra Hospital & Medical Research Centre.
It can lead to an unstable angina – not enough blood and oxygen flow to the
heart causing a heart attack. In patients who already have blockages,
exposure to pollutants tends to accelerate the process.
“Chronic bronchitis also leads to heart disease, though of a different kind. It’s
called cor pulmonale, or enlargement of the heart,” adds Dr Kaul.
Brain damage
The brain is also not spared from the adverse effects of pollution. “When the
heart malfunctions, it automatically affects the brain functioning as well, as
blood or oxygen flow to the brain becomes restricted, which can lead to a
stroke. Also, inhaling pollutants emits certain chemical responses within the
body which can also cause a stroke over a period of time,” says Dr Deepak
Aggarwal, professor, neurosurgery, AIIMS.
https://www.hindustantimes.com/cities/not-just-organs-pollution-can-cause-cellular-damage-too-
experts/story-mOrSSl7PCq1mwLR3e0tY0O.html
Methods
Retrospective study was done to see the number of cases presented
with respiratory symptoms during increased level of air pollution post
Diwali.