NOMISMA HEALTHCARE

info.nomisma@gmail.com

This imaginative and prescient led our

Advance in scientists to never be glad with the
reputation quo. It driven them to elevate the
BIO-POLYMER bar higher and ever higher. It made them give
all of the passion and knowledge they'd into
making BIO-POLYMER the fulfilment story it's
far and could preserve to be.
The history of BIO-POLYMER is
the story of a formidable vision: To
But maximum of all it made them
help obtain a better nice of life for
concentrate very cautiously to you, our
people. customers. Because your needs always have
been and always may be the foremost driving
pressure for our BIO-

Offering limitless opportunities

Nomisma Healthcare offers bioresorbable polymers that not only set enterprise
standards, but also open new guidelines for therapy development.
 Compliance products
PERFOMANCE ENHANCED BY NOVEL SCIENCE

Nomisma Healthcare gives a broad range of biodegradable polymers for clinical

device, parenteral managed drug delivery and regenerative medication
applications.
The polymers we develop and manufacture extend the possibilities for advanced
drug delivery and progressive medical devices.
Semi-crystalline polymers which includes homo- and copolymers of L-lactide, D,L-
lactide, glycolide, caprolactone, dioxanone are normally used to produce medical
gadgets such as orthopedic and soft tissue fixation gadgets.
Amorphous polymers inclusive of homo- and copolymers of D,L-lactide and
glycolide are the key excipients for plenty sustained launch drug delivery systems.
They enhance concentrated on combined with specific delivery timing – for one
or even numerous active pharmaceutical ingredients.

Polymer properties that are outstanding

COALESCING ADOPTABILITY AND CONSTANCY:

The main gain of BIO-POLYMER is that it's miles accurately resorbed with the resource of the
frame after implantation or injection.By amendment of molecular weight and polymer
composition, the degradation rate and mechanical stability can be followed to the individual
requirements of the application.

Degradable polymers do now not pose any handling issues with regard to processing, storage
or safety. They are to be had in granular form – specifically for medical applications – or as a
powder for pharmaceutical formulations. Stability studies are to be had, showing the long-
term shelf existences of the polymer’s conditions. under proper Storage condition.

.
 Validate process standards
CONTINUOUSLY ENLIGHTENING THE STATUS QUO

The polymers are produced by complicated approaches which have been optimized to
guarantee consistent quality.
One key strength is Nomisma Healthcare’s purification procedure that yields material with
very low residual monomer, which is critical for thermal processing and the controlled
delivery of proteins and peptides.
Nomisma Healthcare is your partner via your complete product existence cycle. We help you
during the improvement manner and throughout the economic production with a reliable
supply of high high-quality products. Our manufacturing sites within the India follow the
highest manufacturing and safety standards.
You can determine the scope of our involvement and always expect us for reliable deliver –
around the sector and across the corner.

Quality that can trust on

DELIVERING CERTIFIED PRODUCTS

Technical documentation can be provided for all non-US registrations on request.

 Medical application
BRINGING SPECIALIZED CONCERT

The BIO-POLYMER product portfolio includes polymers for the production of bioresorbable
implants, medical devices and tissue engineering solutions for both repairing bones,
replacing body features or assisting organs repair themselves.
These medical implants can also be combined with pills for controlled release over time.
Bioresorbable plates and screws for trauma and orthopaedic applications, bioabsorbable
stents and coatings for next generation cardiovascular treatments are only a few
merchandises made via our BIO-POLYMER own family of bioresorbable polymers.

The advantages are:

Proven safety track record,
No adverse reactions,
Complete metabolization,
Easy processing.
 Medical device application laboratories
ENGINEERED EXCELLENCE WITH BIO-POLYMER

Our bioresorbable polymers help the medical device industry discover new ways to use the
body ‘s very own regenerative and repair potential.
With our medical tool application laboratories, we assist our customers not most effective
with reliable delivery of materials but also with support on how to best use BIO-POLYMER
for their unique design and production needs.

Extrusion
Selection of the most appropriate polymer for the application
Characterization of production process situations for successful layout and scale-up
Manufacturing of technical samples for feasibility studies

WE HELP YOU DESIGN AND SCALE UP MEDICAL DEVICES FASTER

BIO-POLYMER is synonymous with parenteral controlled launch delivery systems that
maintain pushing the therapeutic frontier, from nanoparticles to drug-eluting films and
particles.
Bioavailability and extra patient comfort, including less complicated self-
administration.

BIO-POLYMER polymers offer scientists more possibilities for targeting and timing of therapies
with greater precision at lower dosages and with more efficacy and fewer side-effects.

A massive number of managed releases in addition to long-acting medicinal drug

transport formulations developed by way of and with us are making a difference in
thousands and thousands of affected persons lives.
Besides imparting the bioresorbable polymers, we are able to paintings with you in
developing the proper and prolonged depot system and manufacture state-of-the-art
injectable products.
We comply with Polymerisation forward by means of direct condensation.
Bio-Polymers are untied from Tin-II and other toxic metals.
Characterised with the aid of various techniques like Proton and 13C-NMR, IR Spectra,
Molecular weight with the aid of GPC, X-Ray diffraction and Glass transition
temperature by means of DSC.
 The areas we sit up for exploring with you are

Besides providing the bioresorbable polymers, we will paintings with you in developing the
proper and extended depot system and manufacture state-of-the-art injectable products

Dynamically responsive biomaterials,

Conductive polymers,
Biomaterials for cellular production,
Biomaterials and scaffolding for bone regeneration,
Biomaterials and scaffolding for neural regeneration,
Cardiovascular biomaterials.

Nanomaterials,
Implants,
High-potency API delivery,
Nanomaterials,
Ophthalmic biomaterials,
Orthopaedic biomaterials,
Dental biomaterials,
Tissue engineering.

This information and all further technical advice are primarily based on our present expertise and
experience. However, it implies no liability or other legal duty on our part. In particular, no
warranty, whether explicit or implied, or guarantee of product properties within the legal sense
is intended or implied. We reserve the proper to make any adjustments according to
technological progress or similarly developments. The customer is not launched from the
responsibility to conduct careful inspection and trying out of incoming goods. Performance of the
product described herein must be verified through checking out, which need to be carried out
most effective by way of qualified specialists in the only obligation of a customer. Reference to
change names utilized by different companies is neither a recommendation, nor does it imply
that similar products couldn't be used.
 BIO-POLYMER product range

CatLog No Polymer Identity Polymer Ratio & End group I.V range / Mw in kDa
NHBP08 DL 100-1A PDLLA 0/100 COOH 0.05-0.20 / 6-20
NHBP09 DL 100-2A PDLLA 0/100 COOH 0.15-0.30 / 10-25
NHBP10 DL 100-5A PDLLA 0/100 COOH 0.40-0.60 / 45-80
NHBP11 DL 100-7A PDLLA 0/100 COOH 0.60-0.80 / 70-120
NHBP12 DLL 10-15A P(L/DL)LA 90/10 COOH 1.30-1.70 / 200-250
NHBP13 DL 100-2E PDLLA 0/100 ESTER 0.15-0.30 / 10-25
NHBP14 DLG 45-2A PLGA 45/55 COOH 0.15-0.30 / 15-30
NHBP15 DLG 50-2A PLGA 50/50 COOH 0.15-0.25 / 5-20
NHBP16 DLG 50-3A PLGA 50/50 COOH 0.25-0.40 / 15-40
NHBP17 DLG 50-5A PLGA 50/50 COOH 0.40-0.55 / 42-65
NHBP18 DLG 50-6A PLGA 50/50 COOH 0.55-0.65 / 60-85
NHBP19 DLG 50-8A PLGA 50/50 COOH 0.65-0.90 / 80-130
NHBP20 DLG 55-5A PLGA 55/45 COOH 0.40-0.50 / 42-65
 NHBP21 DLG 65-3A PLGA 65/35 COOH 0.25-0.35 / 15-40
NHBP22 DLG 65-6A PLGA 65/35 COOH 0.50-0.65 / 45-85
NHBP23 DLG 75-2A PLGA 75/25 COOH 0.08-0.21 / 5-20
NHBP24 DLG 75-5A PLGA 75/25 COOH 0.38-0.64 / 37-84
NHBP25 DLG 75-7A PLGA 75/25 COOH 0.60-0.70 / 65-85
NHBP26 DLG 75-8A PLGA 75/25 COOH 0.70-0.90 / 76-130
NHBP27 DLG 75-10A PLGA 75/25 COOH 0.80-1.10 / 110-166
NHBP28 DLG 85-2A PLGA 85/15 COOH 0.15-0.25 / 10-15
NHBP29 DLG 85-7A PLGA 85/15 COOH 0.55-0.75 / 65-95
NHBP30 DLG 90-5A PLGA 90/10 COOH 0.35-0.55 / 30-70
NHBP31 DLG 90-7A PLGA 90/10 COOH 0.60-0.75 / 50-95
NHBP32 DLG 95-2A PLGA 95/5 COOH 0.15-0.25 / 5-20
NHBP33 DLG 95-4A PLGA 95/5 COOH 0.25-0.50 / 35-60
NHBP34 DLG 50-2E PLGA 50/50 ESTER 0.15-0.25 / 5-20
NHBP35 DLG 50-6E PLGA 50/50 ESTER 0.55-0.65 / 60-85
NHBP36 DLG 50-7E PLGA 50/50 ESTER 0.60-0.70 / 70-100
NHBP37 DLG 65-6E PLGA 65/35 ESTER 0.50-0.65 / 45-85
NHBP38 DLG 75-2E PLGA 75/25 ESTER 0.15-0.30 / 10-25
NHBP39 DLG 75-4E PLGA 75/25 ESTER 0.30-0.50 / 25-60
NHBP40 DLG 75-7E PLGA 75/25 ESTER 0.66-0.80 / 80-115
NHBP41 DLG 75-9E PLGA 75/25 ESTER 0.75-1.00 / 100-160
NHBP42 DLG 85-7E PLGA 85/15 ESTER 0.55-0.75 / 65-95
NHBP43 DLG 85-12E PLGA 85/15 ESTER 1.00-1.30 / 185-210
NHBP44 DLG 50-6P PLGA-PEG 50/50 PEG 0.45-0.65 / 30-60
NHBP45 DLG 50-7P PLGA-PEG 50/50 PEG 0.65-0.80 / 60-85
NHBP46 DLG 75-4A PLGA 75/25 COOH 0.30-0.50 / 25-60

Products available in non-GMP sample form; contact us for a quote on GMP manufacturing.

Nomisma Healthcare
www.nomismahealthcare.in
J-62 Gorwa BIDC,Vadodara Gujarat
India-390003

E mail us: info.nomisma@gmail.com

neha@nomismahealthcare.in

Call us: +91 8200708063

+91 9904447331