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ABSTRACT from the World Health Organization (5). The objectives of the 1st
Research on the effects of dietary polyphenols on human health has International Conference on Polyphenols and Health (Vichy,
developed considerably in the past 10 y. It strongly supports a role for France, November 18 –21, 2004) were to offer an overview of our
polyphenols in the prevention of degenerative diseases, particularly current knowledge on the associations between polyphenol in-
cardiovascular diseases and cancers. The antioxidant properties of take and disease and health and to discuss key issues awaiting
polyphenols have been widely studied, but it has become clear that resolution. More than 350 communications from 쏜 30 countries
the mechanisms of action of polyphenols go beyond the modulation were presented. The articles included in this volume correspond
of oxidative stress. This supplemental issue of The American Jour- to the invited lectures presented at the conference.
nal of Clinical Nutrition, published on the occasion of the 1st Much of the evidence on the prevention of diseases by poly-
International Conference on Polyphenols and Health, offers an over- phenols is derived from in vitro or animal experiments, which are
Am J Clin Nutr 2005;81(suppl):215S–7S. Printed in USA. © 2005 American Society for Clinical Nutrition 215S
216S SCALBERT ET AL