Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
AT KINGSPORT, TENNESSEE
1. I have been retained by the plaintiffs in this litigation to provide my opinion regarding
appropriate and effective programs for treating persons suffering from opioid use disorder
(OUD). I have outlined programs that the State of Vermont has used to expand treatment for
OUD and identified general principles that should inform efforts by Northeast Tennessee
officials to respond to the opioid crisis. As part of my opinion, I have analyzed the likely
prevalence of OUD in Northeast Tennessee and made recommendations about the services
needed to provide needed treatment for individuals with OUD in this area.
II. QUALIFICATIONS
4. When I moved “home” to Vermont in 2015, I was asked by Governor Peter Shumlin and
the Director of the Vermont Department of Health, Harry Chen, to evaluate Vermont’s response
to the opioid crisis. The Vermont Hub and Spoke model (H&S) is an innovative system of
treatment to rapidly expand medication treatment for OUD. In 2017-2018, I visited over 40
clinic sites throughout Vermont and interviewed over 200 individuals in treatment for OUD. I
completed a comprehensive report on this project1 and have published two articles on the results
of the evaluation.2 As a result of this experience I have a thorough understanding of the
treatment services for OUD throughout the state of Vermont.
5. I have published 6 books, 40 book chapters and over 240 professional papers and
annually conduct numerous workshops, paper presentations and training sessions in the US and
internationally. These are listed in my CV, which is included as Attachment A.
6. The present case is the first time I have been paid as an expert witness. The list of
materials I relied upon for this Report is included as Attachment B. My rate for work in this
matter is $300 per hour and $400 per hour of testimony. My compensation does not depend
upon the outcome of this litigation.
1
R. Rawson, “Vermont Hub-and-Spoke Model of Care for Opioid Use Disorders: An Evaluation,” Submitted
December 2017, available at https://www.healthvermont.gov/sites/default/files/documents/pdf/ADAP_Hub_and_
Spoke_Evaluation_2017_1.pdf.
2
R. Rawson et al., “Patient perceptions of treatment with medication treatment for opioid use (MOUD) in the
Vermont hub-and-spoke system,” Preventive Medicine, 2019, pp. 2-6 and R. Rawson et al., “Assessment of
medication for opioid use disorder as delivered within the Vermont hub and spoke system,” Journal of Substance
Abuse Treatment, 97, 2019, pp. 84-90.
7. The United States is currently grappling with an epidemic of opioid abuse and overdose.
Each day, on average, 130 Americans die from an opioid overdose.3 Overdose deaths from
heroin and other opioids have risen sharply over the past decade, now eclipsing deaths from
other external causes, such as gun-inflicted homicides or motor vehicle crashes, and some
experts predict continuing increases in death for the next decade.4 Opioid-related consequences
(e.g., criminality, infectious diseases, overdoses, pre-mature death) have resulted in economic
costs of $56 billion annually.5 The issue of opioid abuse and dependency is so pressing that, in
2017, the Acting HHS Secretary declared a national public health emergency. 6
8. Prescription opioid use is relatively common in the United States. A 2016 survey by
Kaiser Family Foundation and The Washington Post estimated that about 1 in 20 adults in the
United States had recently taken prescription opioids for a period of at least two months, not
including those treated for cancer or terminal illness.7 Among the opioid users surveyed, more
3
Centers for Disease Control and Prevention, “Understanding the Epidemic,” available at https://www.cdc.gov/
drugoverdose/epidemic/index.html.
4
“The Great Opioid Epidemic,” The Washington Post, December 11, 2016, available at
https://www.washingtonpost.com/opinions/the-great-opioid-epidemic/2016/12/11/77bd8998-be4d-11e6-91ee-
1adddfe36cbe_story.html; and M. Blau, “STAT forecast: Opioids could kill nearly 500,000 Americans in the next
decade,” STAT Blog, June 27, 2017, available at https://www.statnews.com/2017/06/27/opioid-deaths-forecast/.
5
W.C. Becker et al., “Non-medical use, abuse and dependence on prescription opioids among U.S. adults:
Psychiatric, medical and substance use correlates,” Drug and Alcohol Dependence, 94, 2008, pp. 38-47; H.G.
Birnhaum et al., “Societal costs of prescription opioid abuse, dependence, and misuse in the United States,” Pain
Medicine, 12, pp. 657-667; T. Clausen et al., “Mortality among opiate users: Opioid maintenance therapy, age and
causes of death,” Addiction, 104, 2009, pp. 1356-1362; C.M. Jones et al., “Vital signs: Demographic and substance
use trends among heroin users: United States, 2002-2013,” Morbidity and Mortality Weekly Report, 64, pp. 719-725;
L.J. Paulozzi, “Prescription drug overdoses: A review,” Journal of Safety Research, 43, 2012, pp. 283-289;
SAMHSA, Opioids, 2016, available at http://www.samhsa.gov/atod/opioids; and A. Wisneiwski et al., “The
epidemiologic association between opioid prescribing, non-medical use, and emergency department visits,” Journal
of Addictive Diseases, 27, 2008, pp. 1-11.
6
U.S. Department of Health & Human Services, “HHS Acting Secretary Declares Public Health Emergency to
Address National Opioid Crisis,” October 26, 2017, available at https://www.hhs.gov/about/news/2017/10/26/hhs-
acting-secretary-declares-public-health-emergency-address-national-opioid-crisis.html.
7
B. DiJulio, B. Wu, and M. Brodie, “The Washington Post/Kaiser Family Foundation Survey of Long-Term
Prescription Painkiller Users and Their Household Members,” Kaiser Family Foundation, December 2016, available
at http://files.kff.org/attachment/Survey-of-Long-Term-Prescription-Painkiller-Users-and-Their-Household-
Members.
9. It is well understood that opioid dependency can be fatal. The annual number of deaths
from opioid overdose has increased dramatically in the United States over the last two decades.
In particular, the age-adjusted mortality rate from opioid overdose increased more than fourfold
between 1999 and 2017, from 2.9 per 100,000 population in 1999 to 14.9 per 100,000 population
in 2017, with much of this increase occurring over just the last decade (See Figure 1).10 The
problem is so severe that 1 in 5 Americans now say they know someone who has died from a
prescription painkiller overdose.11
8
Ibid, p. 1.
9
Ibid, p. 9.
10
Kaiser Family Foundation analysis of CDC WONDER Database: Kaiser Family Foundation, “Opioid Overdose
Death Rates and All Drug Overdose Death Rates per 100,000 Population (Age-Adjusted),” available at
https://www.kff.org/other/state-indicator/opioid-overdose-death-rates.
11
Kaiser Family Foundation, “1 in 5 Americans Say They Know Someone Who Has Died from Prescription
Painkiller Overdose,” January 18, 2018, available at https://www.kff.org/other/slide/1-in-5-americans-say-they-
know-someone-who-has-died-from-prescription-painkiller-overdose/.
10. The opioid epidemic is even more severe in Tennessee than nationally, with the state’s
overdose death rate rising to 19.3 per 100,000 population in 2017, an eleven-fold increase from
1999 (see Figure 1).12 Furthermore, overdose deaths from opioids are rising faster than for other
drugs. By 2017, opioids were responsible for 71% of all drug overdose deaths in the state, up
from about 50% in 2007.13 More than 1,200 people died from an opioid overdose in Tennessee
in 2017 alone, with only about one-quarter of these deaths including heroin as an underlying
cause.14
11. Figure 2 depicts opioid prescribing rates from 2006-2017 in the United States, Tennessee,
and the nine Tennessee counties involved in this matter, with rates expressed as the number of
12
Kaiser Family Foundation, “Opioid Overdose Death Rates and All Drug Overdose Death Rates per 100,000
Population (Age-Adjusted),” available at https://www.kff.org/other/state-indicator/opioid-overdose-death-rates.
13
Kaiser Family Foundation, “Opioid Overdose Deaths and Opioid Overdose Deaths as a Percent of All Drug
Overdose Deaths,” available at https://www.kff.org/other/state-indicator/opioid-overdose-deaths/.
14
Ibid and Kaiser Family Foundation, “Opioid Overdose Deaths by Type of Opioid,” available at
https://www.kff.org/other/state-indicator/opioid-overdose-deaths-by-type-of-opioid/.
FIGURE 2
OPIOID PRESCRIBING RATES IN THE NINE TENNESSEE COUNTIES,
TENNESSEE, AND THE UNITED STATES
15
CDC, “U.S. Opioid Prescribing Rate Maps,” available at https://www.cdc.gov/drugoverdose/maps/rxrate-
maps.html. Data on opioid prescribing rates include prescriptions of “buprenorphine, codeine, fentanyl,
hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, propoxyphene, tapentadol, and
tramadol,” as identified using the National Drug Code. These data do not include: cough and cold formulations
containing opioids; buprenorphine products used to treat opioid use disorder; or methadone dispensed through
methadone maintenance treatment programs. I created one line for the nine Tennessee counties by weighting each
rate by the population for that year. Population data are from: US Census Bureau, “American FactFinder,” available
at https://factfinder.census.gov/faces/nav/jsf/pages/index.xhtml.
12. Prescribing rates in the nine Tennessee counties are even higher than the overall
Tennessee rates, and have historically been among the highest in the country. The prescribing
rate in 2009 in the nine Tennessee counties was extraordinarily high, at 191.6 prescriptions
dispensed per 100 persons. By comparison, the average county-level prescribing rate in the
United States was 90 per 100 persons in 2009, among counties for which data are available.
While the prescribing rate in the nine Tennessee counties has also been declining since 2010, it
remains quite high, at 114.9 per 100 persons.
13. OUD is described as “a problematic pattern of opioid use that causes clinically significant
impairment or distress.”16 A diagnosis of OUD is based on specific assessment criteria from the
Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5), such as unsuccessful efforts
16
“Substance-Related and Addictive Disorders,” in American Psychiatric Association, Diagnostic and Statistical
Manual of Mental Disorders, 5th edition, DSM Library. Arlington, VA, 2013 (hereafter DSM-5) and CDC,
“Commonly Used Terms,” February 12, 2019, available at https://www.cdc.gov/drugoverdose/opioids/terms.html.
A. The National Survey on Drug Use and Health (NSDUH) Provides a Gross
Underestimate of the Prevalence of OUD
14. The origins and limitations of the overdose death estimates described in Section III are
generally well understood. For example, not all medical examiners or coroners conduct
extensive drug tests of decedents, not all tests are comprehensive in the opioids they can detect,
and abuse of multiple substances concurrently may complicate cause of death attribution.19
Therefore, rates of involvement of specific drugs, such as prescription opioids or heroin, in
overdose deaths are likely to be underestimated.20 Nonetheless, there is no doubt that the
number of opioid-related deaths has grown rapidly.
15. The accuracy of estimates of the number of individuals with OUD is less clear. The
source typically used to estimate the number of people who use heroin or misuse prescription
opioids in the US is the National Survey on Drug Use and Health (NSDUH), which has been
conducted annually since 2002. The NSDUH interviews approximately 70,000 people per year
ages 12 and older,21 yielding 330,000 unique individuals interviewed between 2011 and 2016 for
17
Ibid.
18
J. Bose et al., “Key Substance Use and Mental Health Indicators in the United States: Results from the 2017
National Survey on Drug Use and Health,” Substance Abuse and Mental Health Services Administration, September
2018, available at https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/NSDUHFFR2017/
NSDUHFFR2017.pdf.
19
M. Warner, et al., “State variation in certifying manner of death and drugs involved in drug intoxication deaths,”
Academic Forensic Pathology, 3(2), 2013, pp.231-237 and C.J. Ruhm, “Drug poisoning deaths in the United States,
1999–2012: a statistical adjustment analysis,” Population Health Metrics, 14(2), 2016, pp. 1-12.
20
Ruhm, op. cit., pp. 1-2.
21
National Survey on Drug Use and Health, “About the Survey,” available at https://nsduhweb.rti.org/respweb/
about_nsduh.html.
16. There are numerous, well documented reasons why the NSDUH severely underestimates
the actual number of opioid users in the US. Reasons include:
22
I. Binswanger et al., “Release from prison--a high risk of death for former inmates,” New England Journal of
Medicine, 356(2), 2007, pp. 157–165.
23
M. Fendrich, et al., “Validity of drug use reporting in a high-risk community sample: a comparison of cocaine
and heroin survey reports with hair tests,” American Journal of Epidemiology, 149(10), 1999, pp. 955–962.
24
S. Magura, “Validating self-reports of illegal drug use to evaluate National Drug Control Policy: a reanalysis and
critique.” Evaluation and Program Planning, 33(3), 2010, pp. 234-237.
25
Substance Abuse and Mental Health Services Administration, “National Survey on Drug Use and Health,”
available at https://www.samhsa.gov/data/data-we-collect/nsduh-national-survey-drug-use-and-health.
26
D. Kaeble and M. Cowhig, “Correctional Populations in the United States, 2016,” U.S. Department of Justice,
Bureau of Justice Statistics; April 2018, available at https://www.bjs.gov/content/pub/pdf/cpus16.pdf.
27
J. Bronson et al., “Drug Use, Dependence, and Abuse Among State Prisoners and Jail Inmates, 2007- 2009,”
NCJ250546. Washington, DC: Bureau of Justice Statistics, US Department of Justice, 2017.
28
L.D. Harrison et al., “Comparing drug testing and self-report of drug use among youths and young adults in the
general population,” SAMHSA, Office of Applied Studies, May 2007, available at http://buckleysrenewalcenter.
com/wp-content/uploads/2012/02/drugtest.pdf.
FIGURE 4
AGE-ADJUSTED DRUG OVERDOSE DEATHS, BY OPIOID CATEGORY: UNITED STATES 1999-201730
18. Finally, there is direct, incontrovertible evidence that the NSDUH badly underestimates
the number of individuals with OUD. In the most recent state level NSDUH report, the State of
Vermont is estimated to have 6,000 individuals with OUD.31 However, there is excellent
documentation from Medicaid and Vermont’s Department of Health data, that in Vermont in
29
Centers for Disease Control and Prevention, “Understanding the Epidemic,” December 18, 2018, available at
https://www.cdc.gov/drugoverdose/epidemic/index.html.
30
H. Hedegaard, A.M. Minino, and M. Warner, “Drug Overdose Deaths in the United States, 1999-2017,” NCHS
Data Brief, 329, November 2018, available at file:///C:/Users/kdrake/Desktop/db329-h.pdf.
31
SAMHSA, “Behavioral Health Barometer: Vermont, Volume 5,” pp. 1-37 at p. 22, available at
https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/Vermont-BH-BarometerVolume5.pdf.
19. Therefore, in order to accurately estimate the number of people with OUD in the nine
Tennessee counties, and to estimate the number who will need treatment, NSDUH cannot be
relied upon and other estimation methods are needed.
20. In view of the limitations of the NSDUH as a method for estimating the number of
individuals with OUD, researchers have searched for alternative estimation methods. The
prestigious group at RAND Corporation have extensively addressed the methods available for
estimating the number of drug users in the US and they maintain that the NSDUH, while a fine
survey on many health issues, badly underestimates the number of heroin and other opioid
uses.34
32
“More Vermonters are Receiving Needed Medication Assisted Treatment,” Vermont Department of Health, July
2019. available at https://www.healthvermont.gov/sites/default/files/documents/pdf/ADAP_Medication%20
Assisted%20Treatment%20for%20Opioid%20Use%20Disorder%20Trends.pdf.
33
This is based on my personal communications with employees of the Vermont Health Department.
34
P. Reuter, J.P. Caulkins, and G. Midgette, “Measuring Problem Heroin use: Misuse of a General Population
Survey,” under review.
22. In a recent article in the highly respected American Journal of Public Health, Barocas
and colleagues performed a very well designed analysis of multiple datasets of Massachusetts
data and applied a multi-sample stratified capture–recapture analysis to estimate OUD
prevalence in Massachusetts.36 This approach, the capture-recapture methodology, is a
“foundational” methodology when estimating the size of a population in a situation where direct
measures of estimation are not possible. The resulting estimates in Massachusetts from 2011,
show a rapidly increasing percentage of the population, such that by 2015, the estimated
prevalence for OUD in Massachusetts was 4.60% of the population over the age of 11.37
23. The Appalachian region, including Northeast Tennessee, has been the epicenter of the
opioid epidemic.38 As illustrated in Figure 5, a much higher rate of opioids, more than double,
have been prescribed in the nine Tennessee counties compared to Vermont and Massachusetts.39
35
The 2018 population of Vermont over age 13 was 538,502. US Census Bureau, “American FactFinder,”
available at https://factfinder.census.gov/faces/nav/jsf/pages/index.xhtml.
36
J.A. Barocas et al., “Estimated Prevalence of Opioid Use Disorder in Massachusetts, 2011-2015: A Capture-
Recapture Analysis,” American Journal of Public Health, 108(12), 2018, pp. 1675-1681.
37
Ibid., p. 1678.
38
For example, see A.M. Bunting et al., “Clinician identified barriers to treatment for individuals in Appalachia
with opioid use disorder following release from prison: a social ecological approach,” Addiction Science & Clinical
Practice, 13(23), 2018, pp. 2-10.
39
CDC, “U.S. Opioid Prescribing Rate Maps,” available at https://www.cdc.gov/drugoverdose/maps/rxrate-
maps.html. This data includes prescriptions of “buprenorphine, codeine, fentanyl, hydrocodone, hydromorphone,
methadone, morphine, oxycodone, oxymorphone, propoxyphene, tapentadol, and tramadol, were identified using the
National Drug Code. Cough and cold formulations containing opioids and buprenorphine products typically used to
treat opioid use disorder were not included. In addition, methadone dispensed through methadone maintenance
treatment programs is not included in the IQVIA Xponent data.”
24. In addition to a higher rate of prescriptions per person, Tennessee, and Northeast
Tennessee in particular, has consistently had a substantially higher rate of high-risk opioid
prescribing and use than Vermont and Massachusetts.40 Risks of addiction and other adverse
outcomes are dose-responsive, meaning that increased morphine milligram equivalents
(MME) results in increased risks.41 In 2017, Tennessee had the highest mean MME per person
40
L. Schieber et al., “Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United
States, 2006-2017,” JAMA Network Open, 2(3), 2019 pp. 7-9; and J. Baumblatt et al., “High-Risk Use by Patients
Prescribed Opioids for Pain and Its Role in Overdose Deaths,” JAMA Internal Medicine, 174(5), 2014, pp. 796–801.
41
D. Dowell, T. Haegerich, and R. Chou, “CDC Guideline for Prescribing Opioids for Chronic Pain – United
States, 2016,” JAMA, 315(15), 2016, pp.1624-1645; A. Bohnert et al., “Association Between Opioid Prescribing
Patterns and Opioid Overdose-Related Deaths,” JAMA 305(13), 2016, pp. 1315-1321; A. Bohnert et al., “A Detailed
Exploration Into the Association of Prescribed Opioid Dosage and Overdose Deaths Among Patients With Chronic
Pain,” Medical Care, 54(5), 2016, pp. 435–441; T. Gomes et al., “Opioid dose and drug-related mortality in patients
with nonmalignant pain,” Arch Intern Med, 171(7), 2011, pp.686-691; K. Dunn et al., “Opioid prescriptions for
chronic pain and overdose,” Ann Intern Med, 152(2), 2010, pp. 85-92; Y. Liang & B. Turner, “National cohort
study of opioid analgesic dose and risk of future hospitalization,” Journal of Hospital Medicine, 10(7), 2015, pp.
425–431.
FIGURE 6
MORPHINE MILLIGRAM EQUIVALENT BY US COUNTY
25. Similarly, the greater the number of days for which opioids are prescribed, the greater the
risks.44 Each additional week of use has been associated with a 20% increased risk for the
development of OUD or occurrence of an overdose.45 The CDC’s 2016 Guideline for
Prescribing Opioid for Chronic Pain urges prescribers to provide the lowest effective dosage and
42
L. Schieber, et al., op. cit.
43
CDC Vital Signs, “Where you live matters,” July 2017, https://www.cdc.gov/vitalsigns/pdf/2017-07-
vitalsigns.pdf.
44
L. Paulozzi et al., “Risk of adverse health outcomes with increasing duration and regularity of opioid therapy,”
J Am Board Fam Med., 27(3), 2014, pp. 329-338; G. Brat et al., “Postsurgical prescriptions for opioid naive patients
and association with overdose and misuse: retrospective cohort study,” BMJ, 2018, 360.
45
M.Edlund et al.,“The role of opioid prescription in incident opioid abuse and dependence among individuals with
chronic noncancer pain: the role of opioid prescription,” Clin J Pain. 30(7), 2014, pp. 557-564; Brat, et al., op. cit.
26. Although the prevalence of OUD in the nine Tennessee counties is unknown, it is very
likely that the prevalence is higher than the 4.5%-4.6% prevalence in Vermont and
Massachusetts.
27. Over the past decade, as states have attempted to meet the needs of their citizens with
regard to treatment access for individuals with OUD, a number of models have emerged as very
promising. A state model of treatment that has been lauded as one of the most promising
approaches is the Vermont Hub-and-Spoke Model (H&S).
28. Vermont has been significantly impacted by the opioid epidemic. Opioid overdose
deaths in Vermont increased from 43 in 2010 to 114 in 2017.48 Along with the rest of New
England, Vermont has been one of the states most profoundly impacted by the consequences of
the opioid epidemic, fueled by large amounts of prescription opioid misuse and addiction.49 In
46
Dowell, Haegerich, and Chou, op. cit.
47
A. Shah, C. Hayes and B. Martin, “Characteristics of initial prescription episodes and likelihood of long-term
opioid use – United States, 2006-2015,” MMWR Morb Mortal Wkly Rep., 66(10), 2017, pp. 265-269.
48
Kaiser Family Foundation, “Opioid Overdose Deaths and Opioid Overdose Deaths as a Percent of All Drug
Overdose Deaths,” available at https://www.kff.org/other/state-indicator/opioid-overdose-deaths/.
49
Kaiser Family Foundation, “Opioid Overdose Death Rates and All Drug Overdose Death Rates per 100,000
Population (Age-Adjusted),” available at https://www.kff.org/other/state-indicator/opioid-overdose-death-rates; and
Substance Abuse and Mental Health Services Administration, “Behavioral Health Barometer: Vermont, Volume 5:
Indicators as measured through the 2017 National Survey on Drug Use and Health and the National Survey of
Substance Abuse Treatment Services,” HHS Publication No. SMA-19-Baro-17-VT. Rockville, MD: Substance
Abuse and Mental Health Services Administration, 2019.
29. Over the past decade, in response to its opioid epidemic, Vermont has developed an
innovative statewide treatment network to expand treatment for individuals with OUD. This
treatment network is the Care Alliance for Opioid Addiction, or the H&S system, which has
expanded since Governor Shumlin’s 2014 address.51 The purpose of the H&S is to provide
comprehensive, integrated care and improved care coordination for people experiencing opioid
dependence and addiction, while expanding access to medications for OUD (MOUD).52
30. In the H&S model, “hubs” and “spokes” are two types of treatment settings that offer
different levels of support to patients with different levels of need (see Figure 753). Each patient
is treated in the least restrictive setting that is clinically appropriate, and may move between
settings, depending on his or her unique care needs.
50
T.A. Simpatico, “Vermont responds to its opioid crisis,” Preventive Medicine, 80, 2015, pp. 10-11 and H. Epp, “5
Years After Gov. Shumlin Called For Action On Opioids In Vermont, What’s Changed?” Vermont Public Radio,
January 7, 2019, available at https://www.vpr.org/post/5-years-after-gov-shumlin-called-action-opioids-vermont-
whats-changed#stream/0.
51
Ibid.
52
State of Vermont, “Hub and Spoke,” 2019, available at https://blueprintforhealth.vermont.gov/about-
blueprint/hub-and-spoke and The Pew Charitable Trusts, “Innovative Approaches Can Help Improve Availability of
Opioid Use Disorder Treatment,” November 2018, available at https://www.pewtrusts.org/-
/media/assets/2018/11/supti_innovative_approaches_to_treating_opioid_use_disorder.pdf.
53
Figure source: State of Vermont, “Hub and Spoke,” 2019, available at https://blueprintforhealth.vermont.gov/
about-blueprint/hub-and-spoke.
31. “Hubs” are licensed regional opioid treatment programs (OTPs), which offer intensive
treatment for individuals experiencing complex addictions.54 There are nine hubs in the State of
Vermont, which offer daily support to patients and may dispense methadone and/or
buprenorphine.55 Hubs have an extensive staff of MDs with training and experience in
delivering MOUD, as well as staff physicians, nurses, and counselors, who provide intensive
specialty-care addiction treatment. Behavioral treatment staff include licensed clinical social
workers, alcohol and drug counselors, and case managers. Services include urine drug testing,
pregnancy and infectious disease screening, birth control information, and annual physical
exams.
32. By contrast, “spokes” are primary medical care settings located in communities across
the State of Vermont, which serve as Office Based Opioid Treatment (OBOT) settings. Spokes
integrate care for opioid dependence into more general medical care for patients with less
intensive treatment needs.56 While spokes may administer buprenorphine, they are not
54
Ibid.
55
Ibid.
56
Ibid.
57
This is based on my personal communications with employees of the Vermont Health Department.
58
State of Vermont, “Hub and Spoke,” 2019, available at https://blueprintforhealth.vermont.gov/about-
blueprint/hub-and-spoke.
59
For example, see: N.D. Volkow, et al., “Medication-Assisted Therapies – Tackling the Opioid-Overdose
Epidemic,” New England Journal of Medicine, 370(22), 2014, pp. 2063-2066; R.P. Schwartz, et al., “Opioid
Agonist Treatments and Heroin Overdose Deaths in Baltimore, Maryland, 1995-2009,” American Journal of Public
Health, 103(5), 2013, pp. 917-922; R.P. Mattick, et al., “Methadone maintenance therapy versus no opioid
replacement therapy for opioid dependence (Review),” Cochrane Database of Systematic Reviews, 2003(2); R.P.
Mattick, et al., “Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
(Review),” Cochrane Database of Systematic Reviews, 2014(2); and World Health Organization, Guidelines for the
Psychosocially Assisted Pharmacological Treatment of Opioid Dependence, 2009, available at
https://www.who.int/substance_abuse/publications/9789241547543/en/.
60
Rawson, 2017, op cit.
34. Vermont’s H&S system provides a useful benchmark for other areas. Research in the
peer-reviewed literature has documented the benefits of the H&S in expanding access to MOUD
throughout the State of Vermont.62 For example, in an evaluation of the impact of the H&S,
patients treated with MOUD reported dramatic reductions in opioid and other substance use,
overdose, crime, emergency department visits, and hospital stays.63 In addition, treatment with
MOUD in the H&S system is associated with reductions in symptoms of anxiety, depression, and
family conflict.64 In depth-interviews with individuals in treatment in the H&S system suggest
that the medications and other services provided within the H&S system are viewed as very
valuable to individuals in treatment, and that the services provided in the spokes (primary care
clinics) have been especially helpful in facilitating access to care and reducing stigma.65 And the
H&S system may be cost-saving: an economic analysis documented that those individuals with
OUD who are treated in the H&S have significantly lower healthcare costs than opioid addicted
individuals not in treatment.66
35. The H&S model has been lauded by experts as an innovative and effective model for
expanding access to MOUD. During the past five years, there have been numerous reviews of
strategies for expanding MOUD, and the H&S has been one of a very few approaches that are
61
Bipartisan Policy Center, “Tracking Federal Funding to Combat the Opioid Crisis,” March 2019, available at
https://bipartisanpolicy.org/wp-content/uploads/2019/03/Tracking-Federal-Funding-to-Combat-the-Opioid-
Crisis.pdf.
62
J.R. Brooklyn and S.C. Sigmon, “Vermont Hub-and-Spoke Model of care for opioid use disorder: Development,
implementation, and impact,” Journal of Addiction Medicine, 11(4), 2017, pp. 286-292.
63
R. Rawson, et al., “Assessment of medication for opioid use disorder as delivered within the Vermont hub and
spoke system,” Journal of Substance Abuse Treatment, 97, 2019, pp. 84-90.
64
Ibid, p. 87.
65
Rawson et al. (2019), op. cit.
66
M.K. Mohlman et al., “Impact of medication-assisted treatment for opioid addiction on Medicaid expenditures
and health services utilization rates in Vermont,” Journal of Substance Abuse Treatment, 67, 2016, pp. 9-14.
36. In order to promote communication and cooperation between hubs and spokes, the
Vermont Department of Health and Medicaid office hosts a “Learning Collaborative” (LC) on a
quarterly basis for all staff in the H&S system. These LCs are full-day teaching and group
learning forums, led by addiction experts from Dartmouth and UVM, that are designed to
provide staff with guidance on the best evidence-based treatment. The LCs also provide a forum
for H&S personnel to get to know each other, coordinate patient care, and collectively review
data on H&S performance. In the early years of the H&S, LCs were held at least monthly, and
they are currently held at least quarterly. These meetings appear to have been instrumental to the
success of the H&S system.70
37. In addition to the H&S service system, Vermont has four inpatient treatment facilities,
with a total of 80 beds.71 All of these facilities are integrated with the outpatient H&S network
and deliver MOUD as part of their treatment programs. Other OUD services in Vermont
67
The Pew Charitable Trusts, 2018, op cit.; and D. Raths, “Vermont’s Hub-and-Spoke Approach to Opioid
Treatment Catching On,” Healthcare Innovation, May 22, 2018, available at https://www.hcinnovationgroup.com/
population-health-management/article/13030249/vermonts-hubandspoke-approach-to-opioid-treatment-catching-on.
68
R. Chou, et al., “Medication-Assisted Treatment Models of Care for Opioid Use Disorder in Primary Care
Settings,” Technical Brief No. 28, Prepared by the Pacific Northwest Evidence-based Practice Center under Contract
No. 290-2015-00009-I, AHRQ Publication No. 16(17)-EHC039- EF. Rockville, MD: Agency for Healthcare
Research and Quality, December 2016, available at https://effectivehealthcare.ahrq.gov/sites/
default/files/pdf/opioid-use-disorder_technical-brief.pdf.
69
Miele, et al., op. cit.
70
B.R. Nordstrom, et al., “Using a learning collaborative strategy with office-based practices to increase access and
improve quality of care for patients with opioid use disorders.” Journal of Addiction Medicine, 10(2), 2016, pp. 117–
122.
71
This is one area where Vermont’s treatment capacity has room for improvement.
Residential care
38. Although the H&S is the centerpiece of the Vermont opioid response, it is not the only
component. There are four residential treatment programs in Vermont, encompassing 80 beds.
These residential beds are needed for individuals who require high levels of support during their
induction period or during their ongoing care on MOUD. Such individuals can include: younger
patients, pregnant women, patients with co-occurring psychiatric or medical disorders, or
patients on MOUD in the H&S system who are struggling with use of non-opioids, including
benzodiazepines, alcohol, or stimulants. For many of these patients, a period of stabilization and
intensive care is necessary to allow them to have an optimal treatment response. All residential
programs are classified as level 3.7 or 4.0 using the American Society of Addiction Medicine
(ASAM) patient placement criteria, reflecting their ability to care for patients requiring high
levels of care intensity,72 and all provide MOUD as part of their care. Residential care settings
emphasize successful transfer to ongoing care in the H&S system upon discharge.
39. A significant number of individuals in Vermont use less intensive residential settings,
including sober living for varying lengths of stay. Because of the informal nature of these
72
American Society of Addiction Medicine, “What are the ASAM Levels of Care?” May 13, 2015, available at
https://www.asamcontinuum.org/knowledgebase/what-are-the-asam-levels-of-care/.
40. When the opioid epidemic was unfolding in Vermont, and health and policy leaders came
together to discuss service priorities, they decided to focus on reducing overdose deaths and
serious medical consequences from opioid use, including HIV and Hepatitis C. Comprehensive
literature reviews of research inside and outside the US clearly established that syringe exchange
services were among the most effective and cost-efficient methods for reducing the spread of
HIV, Hepatitis C, and other blood-borne diseases, including endocarditis.73 Further, syringe
exchange services were seen both as an outreach opportunity to educate injection drug users
about the benefits of treatment and as an entry point into treatment services in Vermont.
Currently, Vermont has six syringe exchange sites around the state.74
Naloxone distribution
41. As a step in the effort to reduce overdose deaths, in 2013, Vermont implemented an
aggressive program of naloxone distribution.75 During its first year, the effort distributed 1,447
naloxone overdose kits to 1,029 individuals.76 In 2018, this effort has expanded to 7,507 kits to
2,016 individuals.77 Kits and training on their use are dispensed to first responders (i.e., EMTs,
members of fire departments, and police departments), as well as drug users and their family
73
F. Laufer, “Cost Effectiveness of Syringe Exchange as an HIV Prevention Strategy” Journal of Acquired Immune
Deficiency Syndromes, 28, 2001, pp.273-278; D.Vlahov and B. Junge, “The Role of Needle Exchange Programs in
HIV Prevention” Public Health Reports, 113(1), 1998, pp 75-80; F.I Bastos and S.A Strathdee, “Evaluating
Effectiveness of Syringe Exchange Programmes: Current Issues and Future Prospects” Social Science & Medicine,
51, 2000, pp. 1771-1782
74
Personal Communication with Anthony Folland, Vermont Department of Health.
75
Vermont Department of Health, “Naloxone Distribution and Administration in Vermont – Data Brief,” June
2019, available at https://www.healthvermont.gov/sites/default/files/documents/pdf/ADAP_Naloxone_Data
_Brief_1.pdf.
76
Ibid.
77
Ibid.
Recovery coaches
42. One of the major challenges of creating a strong response to the opioid crisis throughout
the US has been the shortage of personnel trained in delivering care to individuals with OUD.
To help respond to this shortage, Vermont has developed a cadre of “recovery coaches,” who use
lived experience from their own recovery to serve as peer support under the supervision of
licensed professionals.79 Recovery coaches work in hospitals, emergency departments, outpatient
medical clinics and syringe exchanges.80 They provide a level of support and assistance that
greatly expands the impact of the professional addiction treatment and health service systems.
78
Ibid.
79
SAMSHA, “Vermont Implements Peer Recovery Structure to Tackle Substance Use,” 2014, available at
https://www.samhsa.gov/homelessness-programs-resources/hpr-resources/vermonts-peer-recovery-structure
80
UVM Medical Center, “Recovery coaching: Peer support for patients with substance use disorder,” July 24, 2019,
available at https://www.burlingtonfreepress.com/story/sponsor-story/uvm-medical-center/2019/07/24/recovery-
coaching-peer-support-patients-substance-use-disorder/1793450001/ ; and Vermont Department of Health, “Peer
Recovery Coaches Provide Support and Assistance in Emergency Departments to Individuals with Substance Use
Disorders,” September 26, 2018, available at https://www.healthvermont.gov/media/newsroom/peer-recovery-
coaches-september-26-2018.
81
M. Faher, “More than 500 Vermont inmates receiving addiction treatment,” VTDigger, January 23, 2009,
available at https://vtdigger.org/2019/01/23/500-vermont-inmates-receiving-addiction-treatment/.
82
Personal Communication with Amy Kelly, Vermont Department of Corrections
44. The principal strategy in Vermont’s response to the opioid crisis has been to expand
MOUD and harm reduction services with the goal of reducing opioid overdose deaths. In the
graph below, it can be seen that from 2014, when the total number of people to receive MOUD
was 5,335, the number has increased to 10,025, almost a 100% increase. As of 2018, 2.6% of
Vermont’s population are receiving MOUD. This per capita rate is far higher than any other
state in the US. These H&S numbers do not present a complete picture. In addition to the
individuals on MOUD, there are individuals who are in other forms of treatment for OUD. In
2017, there were approximately 20 % of the number on MOUD, who were receiving behavioral
treatment, without MOUD (another 2,000). In addition, there are 661 incarcerated individuals
receiving MOUD in Vermont’s jails and prisons, several hundred in the VA program in White
River Junction and 100-200 in cash clinics that are not part of the Vermont H&S system. In
short, the effort to ramp up treatment using MOUD as the primary approach has been remarkably
successful.
FIGURE 8
Overdose deaths
45. As described above, the number one priority for policy makers in the State of Vermont as
they developed their response to the opioid crisis was to implement a set of activities that would
result in fewer overdose deaths, with the H&S system as the primary strategy. As presented in
the figure below, relative to the other 5 states in New England, the increased rate of overdose
deaths has been significantly slowed in Vermont. As seen in the figure, in 2013, the rates of 5 of
the NE states were virtually identical (with the exception of Rhode Island, which was higher).
However, starting in 2014 (the first year of the H&S implementation), the overdose death rate in
Vermont has been consistently lower than the other 5 NE states. Using overdose death rates as a
measure, the H&S and related efforts in Vermont have saved lives, when contrasted to the
neighbor states in NE.
46. In order to determine if patients treated in the Vermont H&S system derived benefits
beyond avoiding overdose death, in October 2016, the Vermont Department of Health awarded
the University of Vermont (UVM) Center for Behavior and Health, in the Department of
Psychiatry, a grant to evaluate the Vermont H&S system for the treatment of OUDs. The primary
objective of the evaluation was to collect data on the impact of participation in the Vermont H&S
system and to assess the usefulness of these services to opioid users.
47. The evaluation report is a 180-page document. In brief the evaluation showed that
individuals treated with MOUD in the Vermont H&S system dramatically reduced their opioid
use. Figure 10 illustrates the magnitude of the reduction in opioid use and injection drug use.
This figure based on a randomly selected group of 80 individuals in treatment in the H&S system
for at least 6 months, shows the change in the number of days of opioid use (and injection) from
Figure 10
60
50
40
30
20
10
0
Any Opioid Use Prescription Illicit Opioids Opioid Treatment Opioid Injection
Opioids without a Medication,
Doctor's without
Prescription Prescription
48. The data from the evaluation found many other major changes: Reductions in cocaine,
methamphetamine and alcohol use, reductions in arrests, days in jail and self-reported days of
criminal activity and reductions in overdose, visits to the emergency department and overnight
stays in the hospital. In addition, patients reported improvement in depression and anxiety,
family functioning and in overall quality of life. The results of the evaluation were
overwhelmingly supportive of the benefits of treatment within the H&S system and are available
in Rawson et al. (2018).
49. Efforts to address low barrier treatments in Chittenden County include buprenorphine
induction in the emergency department at the UVM Medical Center and buprenorphine induction
and maintenance in the syringe exchange program in Burlington and in the hospital ED.
50. As the overdose death data presented above indicate, as a result of Vermont’s robust
response to the opioid crisis, with the H&S service network and the other elements of treatment
and harm reduction, Vermont’s overdose death rate has remained significantly lower than the
other five New England States. As a result of the success of this innovative effort, many other
states are replicating the work in Vermont.
51. However, as illustrated in the overdose death graph above (Figure 9), despite this effort,
the emergence of fentanyl in 2015 to date, has caused the overdose rate in Vermont to continue
upward (albeit at a slower rate of increase than the other NE states). In response to this
continuing overdose death crisis, in Chittenden County, Vermont’s population center, several
new initiatives were undertaken in 2018 to reduce overdose deaths. These two programs are
considered “low barrier” programs, as they bring access to the addicted individuals who are not
willing or able to enter formal treatment programs. These programs offer immediate induction
onto buprenorphine without waiting at the syringe exchange in Burlington (and patients can
remain in treatment at the syringe exchange or transfer into H&S treatment; and induction onto
buprenorphine in the emergency department at the University of Vermont Medical Center,
without waiting during 21 of the 24 hours per day (3 am to 6 am the induction service is not
available), 7 days per week. By lowering the barrier to buprenorphine induction, the goal is to
bring people into treatment who are not accessing the standard H&S treatment services.
Vermont’s goal, as reflected throughout, is to reduce overdose deaths.
52. Although only one year of data is available, the effort appears to be very promising. In
the figure below, the overdose death rate for the state of Vermont is the top line, reflecting an
upward trend through 2018. The second line reflects the death rate in the 13 counties in
Vermont, except for Chittenden County, an upward trend through 2018. The bottom line in the
graph is the overdose death rate in Chittenden County. As can be seen, the upward trend is
53. It is not clear if the reduction in the death rate in Chittenden County can be accounted for
by the development of the low barrier services, but the results look very promising. One fact that
is clear, however, the expanded use of MOUD and other harm reduction services have reduced
the number of people in the State of Vermont who have died from opioid overdose. The primary
priority of the Vermont response to the opioid crisis, initiated in 2013, has been effectively
addressed, although more work is needed.
FIGURE 11
54. In addition to the differences in prescribing and high-risk use described in Section IV.C,
Tennessee’s experience with abuse and diversion, which are related to prescribing rates and
patterns, has been different from Vermont’s. This should inform the Northeast Tennessee
response to the opioid epidemic.
55. Over a decade ago, drug dealers began trafficking prescription opioids through Florida
pharmacies or prescribers for diversion into Tennessee communities, on a route that became
known as the “Florida Pipeline” or “Oxy Express,” referring to Interstate 75.83 Northeast
Tennessee’s proximity to I-75 exposed the region to trafficked prescription opioids. Following a
DEA crackdown in Florida, there was a “squeezing the balloon effect,” and pill mills began
migrating to Tennessee, where there were already a significant number of high-volume
prescribers.84 Tennessee’s struggle with high-volume prescribers continues, and multiple
prescribers and pharmacists have been arrested this year.85 The United States Office of Drug
83
G. Allen, “The ‘Oxy Express’: Florida’s Drug Abuse Epidemic,” NPR Morning Edition, March 2, 2011. available
at http://www. npr.org/2011/03/02/134143813/the-oxy-express-floridas-drugabuse-epidemic; “The government’s
struggle to hold opioid manufacturers accountable,” The Washington Post, April 2, 2017, available at
https://www.washingtonpost.com/graphics/investigations/dea-mallinckrodt/?hpid=hp_hp-top-table-main_dea-
645pm%3Ahomepage%2Fstory&utm_term=.600de72194cb.
84
J. Rannazzisi (Deputy Assistant Administrator, Drug Enforcement Administration), Statement before the Caucus
on International Narcotics Control, United States Senate, “Responding to the Prescription Drug Abuse Epidemic”
Hearing, July 18, 2012, p. 6; G. Kerlikowske (Director of National Drug Control Policy), Statement before the
Caucus on International Narcotics Control, United States Senate, “Responding to the Prescription Drug Abuse
Epidemic” Hearing, July 18, 2012, p. 10. (“There have been notable increases in doctors purchasing oxycodone in
Georgia, Tennessee, and Kentucky. Among oxycodone-purchasing doctors, 21 doctors located in Georgia and 11 in
Tennessee are among the top 100.”); C. Ornstein and R.G. Jones, “As Controlled Substance Use Rises in Medicare,
Prolific Prescribers Face More Scrutiny” National Public Radio, Propublica, USA Today, December 15, 2014,
available at https://www.propublica.org/article/as-controlled-substance-use-rises-in-medicare-top-prescribers-face-
scrutiny (stating, “In 2012, 269 providers wrote at least 3,000 prescriptions for Schedule 2 drugs, ProPublica’s
analysis shows. They were concentrated in a handful of states. Florida led the country with 52 prescribers, followed
by Tennessee with 25.”)
85
See e.g., “12 million pills and 700 deaths: How a few pill mills helped fan the U.S. opioid inferno,” The Los
Angeles Times, June 24, 2019, available at https://www.latimes.com/nation/la-na-pol-pill-mills-linked-to-hundreds-
of-deaths-20190614-story.html; Department of Justice, Press Release, “Appalachian Regional Prescription Opioid
(ARPO) Strike Force Takedown Results in Charges Against 60 Individuals, Including 53 Medical Professionals,”
58. The Northeast Tennessee region is served by only one OTP – Overmountain Recovery
(“Overmountain”), located in Gray, Tennessee, which has capacity to serve 600 patients and a
current census of approximately 275. TennCare does not currently cover methadone; however,
more importantly, Overmountain is too far away for many Northeast Tennessee residents.
59. The Northeast Tennessee treatment landscape presents at least two public health
challenges with regard to buprenorphine: in five rural counties there are insufficient providers, if
any, whereas in in two urban counties buprenorphine is available but often not prescribed
according to best practices that make for sustained effected treatment. For example, there are 34
OBOTs licensed by the Tennessee Department of Mental Health and Substance Abuse Services
in the nine Tennessee counties with Washington and Sullivan Counties containing the majority.92
Carter, Johnson, Unicoi, and Hancock Counties do not have any licensed OBOTs.93 These
smaller, more rural Counties also have many fewer buprenorphine-waivered prescribers
compared to Washington and Sullivan Counties.94 A recent study classified Carter, Hawkins,
and Unicoi Counties as “high-risk” counties, while Johnson and Hancock Counties’ status is
listed as unknown.95
91
J. Fortney et al., “The effects of travel barriers and age on the utilization of alcoholism treatment aftercare,”
American Journal of Drug and Alcohol Abuse, 21, 1995, pp. 391-406; S.K. Schmitt, C.S. Phibbs, J.D. Piette, “The
influence of distance on utilization of outpatient mental health aftercare following inpatient substance abuse
treatment,” Addict Behavior, 28(6), 2003, pp. 1183-92.
92
Tennessee Department of Mental Health and Substance Abuse Services, “Fast Facts: TDMHSAS Licensed Sites”
available at https://www.tn.gov/content/tn/behavioral-health/research/tdmhsas-fast-facts-test-3/fast-facts--tdmhsas-
licensed-sites.html.
93
Ibid.
94
SAMHSA, “Buprenorphine Practitioner Locator” available at https://www.samhsa.gov/medication-assisted-
treatment/practitioner-program-data/treatment-practitioner-locator?field_bup_physician_us_state_value=TN.
95
R.L. Haffajee et al., “Characteristics of US Counties With High Opioid Overdose Mortality and Low Capacity to
Deliver Medications for Opioid Use Disorder,” JAMA Network Open., 2(6), 2019.
61. At the present time, the nine Tennesse counties have 3 residential treatment programs that
provide counseling and non-medication treatments with a combined capacity of 131 beds.99 The
Tennessee Department of Mental Health and Substance Abuse Services 2019 Needs Assessment
for Region 1, which encompasses all of the nine counties in Northeast Tennessee except
Hamblen County, stated that there is a need to “[i]ncrease recovery housing to include peer run
recovery residences, halfway houses, and three-quarter housing options to support treatment
adherence and recovery skills.”100 In support, the Needs Assessment stated:
According to the Tennessee Department of Health (DOH), the overdose rates continue to
rise. In FY 2018, Region 1 crisis data indicates that 3,170 individuals presented to area
hospitals for substance use treatment needs. Similarly, residential treatment needs
continue to rise as court referrals are increasing due to diversionary programs through
Office of Criminal Justice Programs (OCJP). As a result, there are limited beds available
96
See e.g.,“Endless prescription: Suboxone, Subutex plaguing region,” Kingsport Times, July 3, 2016, available at
https://www.timesnews.net/Local/2016/07/03/An-endless-prescription-Suboxone-Subutex-becoming-an-epidemic-
in-the-region; Tennessee Department of Mental Health and Substance Abuse Services, “Tennessee Nonresidential
Buprenorphine Treatment Guidelines, Summer 2018 Update,” (stating “In 2017…there was widespread
acknowledgement of the need for these treatment Guidelines due to the growing prevalence of individuals who have
an opioid use disorder, an increased number of individuals using medication-assisted treatment with buprenorphine,
and diversion issues associated with buprenorphine.”); “TennCare Cut Coverage For Suboxone; A Nashville Doctor
Says Aftermath Shows It Was Being Abused,” Nashville Public Radio, August 23, 2016, available at
https://www.nashvillepublicradio.org/post/tenncare-cut-coverage-suboxone-nashville-doctor-says-aftermath-shows-
it-was-being-abused#stream/0; “Heroin, Buprenorphine Drug Busts on the Rise in Tennessee,” February 10, 2016,
https://www.tn.gov/behavioral-health/news/2016/2/10/heroin-buprenorphine-drug-busts-on-the-rise-in-
tennessee.html; “TDH Finds Some Overdose Deaths Associated With Buprenorphine,” January 18, 2018, available
at https://www.tn.gov/health/news/2018/1/8/tdh-finds-some-overdose-deaths-associated-with-buprenorphine.html.
97
“Local addiction treatment facility raided by federal agents,” Johnson City Press, May 2, 2018, available at
https://www.johnsoncitypress.com/law-enforcement/2018/05/02/Local-addiction-treatment-facility-raided-by-
federal-agents-owner-denies-anything-illegal-or-unethical.html.
98
Ibid.
99
Ibid.
100
Tennessee Department of Mental Health and Substance Abuse Service, “Planning and Policy Council 2019
Needs Assessment Summary,” available at
https://www.tn.gov/content/dam/tn/mentalhealth/documents/planning/FINAL%202019%20NA%20Summary.pdf
62. “Expand transitional recovery housing beyond sober living home” was listed in the
agency’s 2018 Needs Assessment as well, stating that “Oxford House is currently the only
transitional recovery option in Region I. While the number of Oxford House beds have increased
in Johnson City, outlying communities such as Greeneville, Bristol, Kingsport, and Rogersville
are still at a deficit.”102
63. In order to meaningfully address the opioid crisis and harms related to the illegal opioid
market in the region, the nine Tennessee counties should implement a coordinated, fully
integrated plan incorporating the following:
• A system of OUD services located throughout Northeast Tennessee, such that
individuals have ready access to care (30 minutes or less from their home); where
they can be admitted within 72 hours of presenting for admission;
• A netork of connections to treatment, referrals, and “warm handoffs” at each point
of care;
• Continuity of care provided by a multidisciplinary team that can facilitate patient
transitions between various health services and higher and lower levels of service
based on patients’ evolving needs and treatment responses;
• Addiction specialists providing expertise, support, and training for other
providers; and
• Care for psychiatric conditions and complex and challenging patients.
64. Elements of Eastern Tennessee’s system should include: Outpatient settings provide
medication treatment for MOUD, primarily buprenorphine treatment (with naltrexone for
patients as clinically indicated). This network of outpatient sites will provide the majority of
101
Ibid.
102
Tennessee Department of Mental Health and Substance Abuse Services, “Planning and Policy Council, 2018
Needs Assessment Summary,” available at https://www.tn.gov/content/dam/tn/mentalhealth/documents/
planning/2018%20NA%20Summary.pdf.
65. Although this network can serve as the centerpiece of the Eastern Tennessee opioid
response, it will be accompanied by other components to meet the diverse needs of individuals. I
estimate that, based on the effort in Vermont’s and in California’s H&S system,103 approximately
10%-15% of the individuals receiving treatment for OUD should reside in residential care and 3-
5% should reside in an inpatient detoxification facility. These beds are needed for individuals
who need high levels of support during their induction period or during their ongoing care on
MOUD. Individuals who may require this care include: individuals under the age of 21,
pregnant women, patients with co-occurring psychiatric or medical disorders, or patients on
MOUD in the H&S system who are struggling with use of non-opioids, including
benzodiazepines, alcohol or stimulants. For many of these patient categories a period of
stabilization and intensive care is necessary to allow them to have an optimal treatment response.
These programs should meet the ASAM criteria as level 3.7 or 4.0, and they will be required to
promote the use of MOUD as part of their inpatient care and continuing outpatient care.
Emphasis on successfully transferring to ongoing care upon discharge.
Housing
66. Less intensive residential settings, including sober living for varying lengths of stay will
also be critical for a significant number of individuals in Eastern Tennessee. Best estimates from
Vermont are that approximately 10% of individuals receiving treatment need a safe and drug free
environment to stabilize their recovery. It will be important for Tennessee to use facilities that
103
In my opinion, both Vermont and California should improve access to these facilities.
Recovery coaches
67. Recovery coaches who are using lived experience in their own recovery can provide
valuable peer support under supervision of licensed professionals. Recovery coaches are valuable
personnel to working in hospitals, emergency departments, outpatient medical clinics and
syringe exchanges. With the proper training and supervision (which is critical) they can build
bridges between the addiction service providers and other aspects of the health system.
104
For example, see Zaller et al., “Intitiation of buprenorphine during incarceration and retention in treatment upon
release,” Journal of Substance Abuse Treatment, 45(2), August 2013, pp. 222-226.
105
For example, see C. Moraff, “Pennsylvania DOC to Pilot Injectable Buprenorphine for Detoxing Prisoners,”
available at https://filtermag.org/pennsylvania-doc-to-pilot-injectable-buprenorphine-for-detoxing-prisoners/.
Training and Technical Assistance Services Needed to Build the Eastern Tennessee System
71. Eastern Tennessee will need a very ambitious implementation plan to scale up the
treatment services rapidly and build treatment capacity. For that purpose it could use the model
described by Miele and colleagues.108 The Eastern Tennessee implementation plan will be
designed to: increase the number and capacity of waivered buprenorphine prescribers; enhance
skills of prescribers and multidisciplinary teams; promote enrollment of individuals with OUD
into treatment and create a coordinated regional system of opioid treatment and support services.
The training and technical assistance activities will include: Buprenorphine waiver trainings and
provider support, a practice facilitator program that will provide mentoring to new prescribers,
Project ECHO sessions and webinars to provide clinical guidance on common clinical challenges
in treating individuals with OUD and in-person clinical skills trainings. In addition, regional
Learning Collaboratives will be created to ensure communication and cooperative relationship
building among the different practitioners and organizations involved in service delivery in
Eastern Tennessee.109 These quarterly regional Learning Collaborative meetings will help
106
Miele et al., op. cit.
107
Simpatico, op. cit.
108
Miele et al., op. cit.
109
Nordstrom et al., op. cit.
72. Tennessee has not expanded Medicaid, which has been an essential component of
Vermont’s progress in combatting the opioid epidemic. The Tennessee agency charged with
addressing substance abuse treatment, the Tennessee Department of Mental Health and
Substance Abuse Services, is under-funded and ill-equipped to facilitate the system
transformation needed to address the crisis in Northeast Tennessee. Publicly-funded programs
present an opportunity to reconfigure and link services so that “systems of care—collections of
services, structures, and processes that are purposively designed and interconnected in order to
treat substance use disorder systematically—can maximize the clinical impact and cost
efficiency of substance use disorder treatment.”111 In the past, these efforts have failed due to
challenges related to planning, logistics, provider resistance, and resource scarcity.112
73. It is well-documented that Northeast Tennessee, like the Appalachian region generally,
has been more severely impacted by the opioid epidemic than other areas, and the nature of the
opioid epidemic in the region presents a unique set of challenges and issues.113 This supports the
need for a region-driven, locally-coordinated response. Data shows that the odds of adopting
pharmacotherapies were significantly greater in government owned programs.114 Studies have
also shown that nonelderly adults with OUD who had Medicaid were significantly more likely to
110
See https://joingroups.com/.
111
H. Padwa et al., “Organizing Publicly Funded Substance Use Disorder Treatment in the United States: Moving
Toward a Service System Approach,” Journal of Substance Abuse Treatment, 69, 2016, pp. 9-18.
112
Ibid.
113
B. Paykamian “Local treatment and prevention expert weighs in on Tennessee opioid statistics,” Johnson City
Press, November 29, 2018, available at https://www.johnsoncitypress.com/Health-Care/2018/11/28/Tennessee-
ranks-first-in-opioid-sales-consumer-report-says
114
H. Knudsen et al., “Facilitating Factors and Barriers to the Use of Medications in Publicly Funded Addiction
Treatment Organizations,” Journal of Addiction Medicine, 4(2), 2010, pp. 99–107.
Conclusion
74. Dr. Stern has outlined a plan to supplant the existing, fragmented treatment system in
Eastern Tennessee with a county-funded system that is at least partially modeled on Vermont’s
H&S system. Dr. Stern estimates that his system could engage 10,000 patients within five years.
Based on my understanding of the situation in Eastern Tennessee, my experience in Vermont, as
well as my correspondence with Cooper Zelnick of Groups, I believe that Dr. Stern’s estimates
are conservative in the sense that they might be able to scale up treatment capacity even faster.
115
Henry J. Kaiser Family Foundation, “The Opioid Epidemic and Medicaid’s Role in Facilitating Access to
Treatment,” available at https://www.kff.org/medicaid/issue-brief/the-opioid-epidemic-and-medicaids-role-in-
facilitating-access-to-treatment/.
116
“State and Local Policy Levers for Increasing Treatment and Recovery Capacity to Address the Opioid
Epidemic: Final Report,” available at https://aspe.hhs.gov/system/files/pdf/259511/SLlevers.pdf; Padwa, et al., op.
cit.
117
Ibid.
Curriculum Vitae
Dec 10, 2018
PERSONAL HISTORY
EDUCATION
PROFESSIONAL EXPERIENCE
2016 - Present Research Professor, Center for Behavior and Health, Department of Psychiatry, University
of Vermont, Burlington Vermont
2016 - Present Professor Emeritus, Department of Psychiatry and Biobehavioral Sciences, UCLA, Los
Angeles California
2012 – Present Adjunct Clinical Professor, Department of Psychiatry, University of Hawaii, Manoa,
Honolulu, Hawaii
2013 – 2015 Co-Director, UCLA Integrated Substance Abuse Programs (ISAP), UCLA Department of
Psychiatry and Biobehavioral Sciences, Los Angeles, CA.
2006 – 2015 Professor-in-Residence, UCLA Department of Psychiatry and Biobehavioral Science, Los
Angeles, CA.
1995 – 2013 Associate Director, UCLA Integrated Substance Abuse Programs (ISAP),
UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA.
1999 – 2006 Adjunct Associate Professor, UCLA Department of Psychiatry and Biobehavioral Science,
Los Angeles, CA.
1996 – 2001 Director of Research, NIDA Medication Development Unit, Long Beach Veterans Affairs,
Long Beach, CA.
1988 – 1998 Executive Director and Board Member, Matrix Institute on Addictions, Los Angeles, CA.
1984 – 1998 President and Chairman of the Board, Matrix Center, Los Angeles, CA.
1979 – 1984 Director of Operations, Community Health Projects, West Covina, CA.
1978 – 1980 Assistant Research Psychologist, Department of Psychiatry, New York Medical
College, NY.
1974 – 1978 Assistant Research Psychologist, Department of Psychiatry, UCLA, Los
Angeles, CA.
Richard A. Rawson, PhD
PROFESSIONAL ACTIVITIES
Editorial Services
2016 – Present Executive Board and Editorial Board, International Addiction Review
2014 – Present Associate Editor, Journal of Studies on Alcohol and Drugs
2009 – Present Editorial Board, Journal of African Behavioral Health
2004 – 2007 Editorial Board, NIDA Science & Practice Perspectives
2001 – 2010 Associate Editor, Journal of Substance Abuse Treatment
Continuous Ad hoc reviewer for numerous journals
2007 Guest Editor for Addiction special issue on Methamphetamine.
2003 Guest Editor for the Journal of Psychoactive Drugs special issue on California Policy Issues
2002 Guest Editor for the Journal of Drug Issues special issue on Practice-Research Integration
2002 Guest Editor for the Journal of Substance Abuse Treatment special issue on Blending Practice
and Research
2002 Guest Editor for the Journal of Addictive Diseases special issue on
Methamphetamine
2000 Guest Editor for the Journal of Psychoactive Drugs special issue on Methamphetamine
1996 – 1999 Member of the Editorial Advisory Board for the CSAT Treatment Improvement Protocol
(TIPs)
1994 – 1998 Editorial Board for Journal of Maintenance in the Addictions
1993 – 1997 Editorial Board of Behavioral Healthcare Management Magazine
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Richard A. Rawson, PhD
Member SAMHSA-sponsored training team to work with the Iraqi Health Ministry on substance
abuse treatment, Cairo, Egypt, March 2006
Co-Chair Governor’s (California) Commission on Methamphetamine, 2006-2007
3
Richard A. Rawson, PhD
2007-2012 Principal Investigator, NIDA Institutional Training Grant. $1,500,000. National Institute
on Drug Abuse
2008-2010 Principal Investigator, Double-blind, Placebo Controlled Trial of Bupropion for
Methamphetamine Dependence, NIDA Contract, $1,200,000.
2008-2010 Principal Investigator, Evaluation of the Co-occurring Disorders Court. $157,000.
Funded by L.A County Department of Alcohol and Drug Programs.
2008-2009 Principal Investigator, Continuum of Services Redesign. $480,000. Funded by the
State of California.
2007-2008 Co-principal Investigator, Training Contract to Improve Treatment for Individuals with
Co-occurring Disorders $2,250.000. Funded by LA County Department of Mental
Health, Thomas Freese, PI.
2007-2008 Principal Investigator, CARE Evaluation Contract. $250,000. Funded by the State of
California.
2007-2008 Principal Investigator, California Outcomes Measurement System (CalOMS) Evaluation
Contract. Funded by the State of California, $630,000.
2005-2007 Principal Investigator, Double-blind, Placebo Controlled Trial of Modafinil for
Methamphetamine Dependence, NIDA Contract, $575,000.
2007-2011 Principal Investigator, LA County Evaluation System: An Outcomes Reporting Program
(LACES), Phase III. Funded by the County of Los Angeles, California, $980,000.
2005-2007 Principal Investigator, Training and Capacity Building Center for the UNODC Worldwide
Network of Substance Abuse Resource Centers. Funded by the UNODC, $480,000.
2005-2010 Co-principal Investigator, Four Models of Telephone Support for Stimulant Recovery,
$2,585,197, NIDA, David Farabee, PI.
2005-2007 Co-principal Investigator, Children Endangered by Methamphetamine Use and
Manufacture, NIDA, $387, 400, Nena Messina, PI.
2005-2010 Co-principal Investigator, Cognitive Behavioral Therapy for the Republic of South
Africa, NIDA $1,487,500, Donnie Watson, PI.
2005-2009 Principal Investigator, UCLA Access to CARE Project, SAMHSA, $1,500,000.
2003-2005 Principal Investigator, Double-Blind, Placebo Controlled Study of Ondansetron for the
Treatment of Methamphetamine Dependence. UCLA ISAP, NIDA, Methamphetamine
Clinical Trials Group, $500,000.
2002-2005 Principal Investigator, Double-Blind, Placebo Controlled Study of Bupropion for the
Treatment of Methamphetamine Dependence. UCLA ISAP, NIDA, Methamphetamine
Clinical Trials Group; NIDA $2,042,000.
2004-2005 Co-principal Investigator, Using Drug Abuse Research to Build Cooperation in the
Middle East, $45,000, U.S. Institute of Peace, Darren Urada, PI.
2004-2007 Principal Investigator, Los Angeles County Evaluation System (LACES). Contract with
LA County Office of Alcohol and Drug Programs, $950,000.
2003-2008 Principal Investigator, Methamphetamine Clinical Trials Group. A contract with NIDA,
$8,000,000. Walter Ling, PI of Medication Development Services Master Contract.
2002-2003 Principal Investigator, Substance Abuse Research Training in South Africa, NIDA,
$75,000.
2002-2007 Principal Investigator, Pacific Southwest Regional Addiction Technology Transfer
Center (ATTC). Funded by CSAT, $2,200,000.
2002-2004 Principal Investigator, An Expansion of the Drug Abuse Early Warning System to
include Data Collection in Egypt. U.S. Department of State: Middle East Regional
Cooperative Grant to UCLA, $500,000.
2001-2003 Principal Investigator, A Drug Abuse Warning System for Israeli and Palestinian
Communities. U.S. Department of State: Middle East Regional Cooperative Grant to
Friends Research Institute, $500,000.
2001-2004 Co-principal Investigator. (Patricia Marinelli-Casey, PI) CSAT Methamphetamine
Special Studies Contract $5,750,000.
2001-2006 Co-principal Investigator. (Barry Lester, PI) Prenatal Effects of Methamphetamine.
NIDA Grant to Brown University with UCLA serving as a subcontractor for site
coordination and data management. Subcontract, $880,000.
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Richard A. Rawson, PhD
2000-2005 Principal Investigator, NIDA Methamphetamine Medication Network. Part of the NIDA
Contract to UCLA Thomas Newton, Contract PI, $10,000,000.
2001-2004 Principal Investigator, CSAT Practice Improvement Collaborative (Phase 2),
$1,042,000.
2000-2001 Co-Principal Investigator, (Natasha Brown, PI.) CSAT Practice Research Collaborative.
(Phase 1) $200,000.
1999-2004 Co-Principal Investigator, (Michael Prendergast, PI) Application of Positive
Contingencies in a Drug Court Setting. NIDA Grant to UCLA, $1,950,000.
1999-2001 Principal Investigator, Factors Influencing the Implementation of Naltrexone for the
Treatment of Alcoholism. Robert Wood Johnson Foundation Grant to Friends Research
Institute, $340,000.
1998-2003 Principal Investigator, Psychosocial Treatment Dose: A Prospective Evaluation. NIDA
Grant to Friends Research Institute, $2,1400,000.
1999-2004 Co-principal Investigator (M.D. Anglin, PI), Los Angeles County Alcohol and Drug
Program Outcome Project. Los Angeles County Contract with UCLA, $1,250,000.
1998-2001 Co-principal Investigator, Coordinating center for methamphetamine treatment project. A
CSAT Grant to UCLA, $2,400,000.
1997-1998 Principal Investigator SCH 39166 for Cocaine Dependence and contract from Schering
Plough awarded to Friends Research Institute, $350,000.
1997-1998 Principal Investigator, The implementation of LAAM: Factors affecting the use of a new
opiate addiction treatment alternative. A Robert Wood Johnson Foundation grant awarded
to Friends Research Institute, $203,906.
1997-2001 Co-principal Investigator, (A. Huber, PI) Medication/behavior therapy for
methamphetamine abuse (1R01 DA10923). NIDA Grant, to Friends Research Institute,
$1,788,253.
1997-1998 Co-principal Investigator, (S. Shoptaw, PI) Acamprosate for alcohol dependence. A contract
from Lipha Pharmaceutical awarded to Friends Research Institute, $250,000.
1996-2000 Co-principal Investigator, (M.D. Anglin, PI) LAAM maintenance: HIV risk reduction
potential and application. NIDA Grant, to UCLA DARC, $2,584,080.
1996-1999 Co-principal Investigator, (S. Shoptaw, PI) Contingency management-tobacco smoking in
opiate addicts NIDA grant, Friends Research Institute, $709,802.
1995-1997 Co-principal Investigator, (S. Shoptaw, PI) A structured treatment manual for HIV+
substance abusers. NIDA, Small Business Innovative Research (SBIR), Phase II Grant to
Matrix Center, $727,069.
1994-1999 Principal Investigator, Behavioral/Cognitive trial for cocaine abuse. NIDA Grant to Friends
Medical Science Research, Inc. $1,939,653.
1993-1998 Co-principal Investigator, (Y. Hser, PI) Drug treatment counselors: Current practices and
effectiveness. NIDA Grant to UCLA, $2,546,347.
1993-1994 Principal Investigator, Ritanserin for alcohol abuse. A contract from Janssen Foundation to
Matrix Center, $350,000.
1992-1994 Principal Investigator, Ritanserin for cocaine abuse. A contract from Janssen Foundation to
Matrix Center, $545,000.
1993-1994 Co-principal Investigator, (S. Shoptaw, PI) A structured treatment manual for HIV+
Substance Abusers. NIDA, Small Business Innovative Research (SBIR), Phase I Grant to
Matrix Center, Inc. $72,453.
1991-1992 Principal Investigator, A rehabilitative framework for methadone treatment. A contract
from the State of California to Matrix Institute, $125,000.
1991-1996 Co-Principal Investigator, (M D. Anglin, PI), UCLA center on treatment careers. NIDA
Center grant to UCLA, $4,132,063.
1993-1995 Principal Investigator, A structured manual to facilitate naltrexone treatment. NIDA, Small
Business Innovative Research (SBIR), Phase II Grant to Matrix Center, $472,600.
1991-1992 Principal Investigator, A structured manual to facilitate naltrexone treatment. NIDA, Small
Business Innovative Research (SBIR), Phase I Grant to Matrix Center, $38,450.
1991 Principal Investigator, The Matrix model of alcoholism treatment. NIAAA, Small Business
Innovative Research (SBIR), Phase I Grant to Matrix Center, $49,075.
5
Richard A. Rawson, PhD
1989-1994 Principal Investigator, Treatment of stimulant users to reduce HIV transmission. NIDA
Research Demonstration Project to Friends Medical Research, Inc., $3,102,371.
1990-1992 Principal Investigator, A neurobehavioral model for outpatient cocaine addiction treatment.
NIDA, SBIR Phase 2 Grant to Matrix Center, $499,075.
1988-1989 Principal Investigator, A neurobehavioral model for outpatient cocaine addiction treatment.
NIDA, SBIR Phase 1 Grant to Matrix Center, $49,725.
1988-1991 Co-principal Investigator, (F. Castro, PI) Matches and mismatches in treatment for cocaine
users. NIDA grant to San Diego State University, $450,000.
1985-1986 Principal Investigator, Lofexidine hydrochloride for methadone withdrawal. Merrill-Dow
Contract, $40,000.
1980-1981 Principal Investigator, Clonidine hydrochloride for opiate detoxification. Boeringer
Engelheim Contract, $50,000.
1978-1980 Project Director, Naltrexone and psychotherapy for opiate addiction. (R. Resnick, PI) NIDA
grant to New York Medical College, $120,000.
1978-1981 Co-principal Investigator and Project Director. (R. Coombs, PI) "Social and familial
components of combined use of alcohol and other drugs in a youthful population." State of
California Office of Alcoholism Grant to UCLA, $200,000.
1978-1979 Co-principal Investigator and Project Director, (R. Coombs, PI) Family strengthening to
redirect drug-prone youth. NIDA grant to UCLA, $600,000.
1974-1977 Co-principal Investigator and Project Director, (E.J. Callahan, PI) Heroin antagonist and
learning therapy for opiate addiction. NIDA grant to UCLA, $525,000.
Selected Presentations
2019 Medication treatment for opioid use disorders, Burlington City Council, Burlington
Vermont, March 2019.
2019 Treatment for opioid addiction. Training seminar for Vermont law enforcement personnel,
March, 2019.
2019 Wisconsin Annual Addictions Conference, Update on Stimulant use trends and treatments.
Green Bay Wisconsin. March 2019.
2019 Expansion of medication assisted treatment for OUD with the Hub and Spoke, Green Bay,
Wisconsin, March 2019.
2019 Treatments for methamphetamine use disorders by men who have sex with men, UVM
Department of Infectious Diseases, Burlington Feb 2019.
2019
2019 Treatment of stimulant use disorders. Webinar for San Francisco Dept of Public Health,
San Francisco Cal
2012–2018 Every year, I conducted 30–50 presentations/training sessions/workshops in the United
States . Topics include research on physical exercise, health system development,
performance measures, cognitive behavioral strategies, use of screening and brief
interventions, addiction medications, methamphetamine, research methods, and
epidemiology of drug use in Iraq.
2018 WHO Regional meeting on treatment systems for SUD, Elements of a Treatment system.
Abu Dhabi, Nov 2018
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Richard A. Rawson, PhD
7
Richard A. Rawson, PhD
8
Richard A. Rawson, PhD
9
Richard A. Rawson, PhD
10
Richard A. Rawson, PhD
June 6-10
2010 Invited Speaker, Kasr Al-Ainy International Psychiatry Conference. Cairo, Egypt.
“Licensing Counselors and Psychotherapists in Egypt.” Feb. 20-27.
2009 Invited Speaker, Society for the Study of Addiction Annual Symposium. York, United
Kingdom. “Treatment Policy.” Nov. 12.
2009 Invited Plenary Speaker, The International Society of Addiction Medication Anniversary
meeting. Calgary, Alberta, Canada. “An Update on the Biopsychological Management of
Stimulant Dependence.” Sept. 23-27
2009 Lead Trainer, UNODC: Drug Dependence Treatment and Care: Master Trainers
Workshop. Vienna, Austria. May 24-28.
2009 Consultant, 4th Sino-US Training Program of Psychological Counseling and Therapy on
Substance Dependence. Shanghai, China. April 4-12.
2009 Consultant, National Rehabilitation Center and International Society of Medicine. Abu
Dhabi, UAE, and Cairo, Egypt. Feb. 10-23.
2009 Training Expert for Vietnamese Ministry of Health, Hanoi, Vietnam
2008 International Society of Addiction Medicine: Meth: New Knowledge. Cape Town, South
Africa.
2008 International Society of Addiction Medicine Pre-Conference: Meth Treatment. Cape
Town, South Africa
2008 First International Global Institute on Methamphetamine, Prague, Czech Republic
2008 Cracked but Not Broken Conference, Vancouver, BC
2008 Invited Speaker, International Society of Addiction Medicine, Cape Town, South Africa.
2008 Invited Speaker, World Methamphetamine Conference, Prague, Czech Republic.
2007 Conference Chair. Delivery Systems for Substance Abuse Treatment: Integration with
Primary Care and Mental Health and Social Services, Istanbul, Turkey Sept 3-6.
2007 Invited Speaker, Recent Advances in Methamphetamine Treatment, Vancouver, Canada.
2006 Invited Speaker: Bridges Have Been Built: Is Anyone Using Them? Amsterdam,
Netherlands
2006 Chair for the UNODC Treatnet Orientation, Cairo, Egypt.
2006 Invited Speaker, Advances in Addiction Treatment, Jeddah, Saudi Arabia.
2006 Methamphetamine and the Brain: New Knowledge; New Treatments, (US Embassy),
Vienna, Austria
2006 Invited Speaker, International Conference of Counselors in Addiction, Edinburgh,
Scotland.
2005 Invited Speaker, Methamphetamine: New Knowledge, United Nations Office of Drugs and
Crime, Vienna, Austria.
2005 Invited Speaker, Innovations in Substance Abuse Treatment, Beirut, Lebanon
2005 Invited Speaker, Recent Advances in the Integration of Substance Abuse Research and
Practice in the U.S. Radboud University, Nijmegen, Netherlands.
2005 Invited Speaker, Ministry of Health, Muscat, Oman.
2005 Methamphetamine: Brain and Behavior-Research Findings, Treatments for
Methamphetamine, Saskatoon, Saskatchewan
2004 Speaker at World Psychiatry Association Conference, Cairo, Egypt.
2004 Invited Speaker, Substance Abuse and Culture Conference, Vienna, Austria.
2004 Invited Speaker, World Health Organization, North Africa Region, Cairo, Egypt.
2004 Invited Speaker, United Nations Office on Drugs and Crime, Middle East Region, Cairo,
Egypt.
2004 Speaker at Grand Rounds, Ain Shams University, Cairo, Egypt
2004 Co-chair and Speaker, Delivery Systems for Substance Abuse Treatment conference,
Istanbul, Turkey.
2004 Invited Speaker, ISAM meeting, Helsinki, Finland.
2004 Invited Speaker, Ministry of Health, Bratislava, Slovakia.
2004 Speaker at Grand Rounds, Department of Psychiatry, University of Cairo, Egypt.
2004 Invited Speaker, First African Conference on Social Psychiatry, Johannesburg,
South Africa.
2003 Speaker at Grand Rounds, Department of Psychiatry, University of Cairo, Cairo, Egypt.
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Richard A. Rawson, PhD
2003 Speaker at Grand Rounds, Department of Psychiatry, University of the Free State,
Bloemfountain, Republic of South Africa.
2003 Invited Speaker to the Israeli Society of Addiction Medicine, Tel Aviv, Israel.
2002 Invited Speaker to Addictions 2002 Conference in Amsterdam, Netherlands.
2002 Invited Speaker to the International Society of Addiction Medicine Meeting, Reykjavik,
Iceland.
2000, 2001 Trainer for U.S. Dept. of State on Stimulant Abuse Treatment, Bangkok, Thailand.
2000 Invited Speaker for the NIDA Conference on Methamphetamine, Budapest, Hungary.
2000 Invited Speaker on Addiction Pharmacotherapies, Amsterdam, Netherlands.
2000 Trainer for U.S. Department of State on Stimulant Abuse Treatment, Tijuana, Guadalajara,
and Mexico City.
1999, 2001 Invited Speaker at the U.S.-Mexico Bi-national Conferences on
Substance Abuse Treatment, Mexico City, Mexico.
1999 Keynote Speaker on Research to Practice Issues, International Congress
on Substance Abuse, Vienna, Austria.
1999 Invited Representative for NIDA on Substance Abuse Treatment at the
U.S.-Netherlands Bi-National Substance Abuse Program. Amsterdam,
Netherlands.
1997, 1998 Consultant to the Economic Cooperation Foundation (Oslo Peace
Accord Organizers) on Addiction Training in West Bank and Gaza,
Palestinian Authority, weeklong addiction training at Al Quds University,
Ramallah, Palestinian Authority.
1997 Consultant to Swiss Government on Psychosocial Treatment Issues for
Substance Abuse Disorders, Thun, Switzerland.
1997 Invited Speaker. Addiction and Society, Presented for the Palestinian Authority Health
Committee, Arafat Health Center, Khan Younis, Gaza, November
1997 Keynote Speaker for Palestinian and Israeli People Against Substance
Use, Beersheva, Israel, November
BIBLIOGRAPHY
RESEARCH PAPERS
12
Richard A. Rawson, PhD
8. Joffe, J.M., Mulick, J.A., Ley, K.F., & Rawson, R.A. (1978). Effects of prenatal stress procedures on maternal
corticosterone levels and behavior during gestation. Bulletin of the Psychonomic Society, 11(2), 93-96.
9. Joffe, J.M., Rawson, R.A., & Mulick, J.A. (1973). Control of their environment reduces emotionality in rats.
Science, 180, 1383-1384.
10. Washton, A.M., Resnick, R.B., & Rawson, R.A. (1979). Clonidine Hydrochloride: A non-opiate treatment for
opiate withdrawal. Proceedings of the Committee on Problems of Drug Dependence. NIDA Research Monograph,
27, 233-239.
11. Rawson, R.A., Glazer, M., Callahan, E.J., & Liberman, R.B. (1979). Naltrexone and behavior therapy for heroin
addiction. In N. Krasnegor (Ed.), Behavioral approaches to analysis and treatment of substance abuse. NIDA
Research Monograph, June (25), 26-43.
12. Callahan, E.J., Rawson, R.A., McCleave, B., Arias, R., Glazer, M., & Liberman, R.P. (1980). The treatment of
heroin addiction: Naltrexone alone and with behavior therapy. The International Journal of the Addictions, 15(6),
795-807.
13. Tennant, F.S., & Rawson, R.A. (1980). Heroin detoxification, Nurse Practitioner, 5, 35-39.
14. Washton, A.M., Resnick, R.B., & Rawson, R.A. (1980). Clonidine for opiate detoxification. Communication to
Lancet, 1(8177), 1078-1079.
15. Tennant, F.S., Rawson, R.A., & McCann, M.J. (1981). Withdrawal from chronic phencyclidine (PCP) dependence
with desipramine. American Journal of Psychiatry, 138, 845-847.
16. Tennant, F.S., & Rawson, R.A. (1981). Propoxyphene napsylate maintenance treatment for narcotic dependence:
A non-methadone model. Drug and Alcohol Dependence, 8, 79-83.
17. Rawson, R.A., Tennant, F.S., & McCann, M.J. (1981). Characteristics of 68 chronic phencyclidine abusers who
sought treatment. Drug and Alcohol Dependence, 8, 223-227.
18. Rawson, R.A., Mann, A.J., Tennant, F.S., & Clabough, D. (1982). Efficacy of psychotherapeutic counseling during
21 day ambulatory detoxification. Proceedings of the Committee on Problems of Drug Dependence. NIDA
Research Monograph, 43, 310-314.
19. Tennant, F.S., & Rawson, R.A. (1982). Cocaine and amphetamine dependence treated with Desipramine.
Proceedings of the Committee on Problems of Drug Dependence. NIDA Research Monograph, 43, 351-355.
20. Tennant, F.S., & Rawson, R.A. (1982). Outpatient treatment of prescription opioid dependence: Comparison of
two methods. Archives of Internal Medicine, 142, 1845-1847.
21. Tennant, F.S., Rawson, R.A., Cohen, A.M., Tarver, A., & Clabough, D. (1983). Methadone plasma levels and
persistent drug abuse in high dose maintenance patients. Substance and Alcohol Actions/Misuse, 4, 369-374.
22. Tennant, F.S., & Rawson, R.A. (1983). Guanabenz Acetate: A new long acting alpha-two adrenergic agonist for
opioid withdrawal. Proceedings of the Committee on Problems of Drug Dependence. NIDA Research Monograph,
49, 338-343.
23. Rawson, R.A., Mann, A.J., Tennant, F.S., & Clabough, D. (1983). Efficacy of psychotherapeutic counseling during
21-day ambulatory heroin detoxification. Drug and Alcohol Dependence, 12, 197-200.
24. Tennant, F.S., Tarver, A., & Rawson, R.A. (1983). Clinical evaluation of mecamylamine for withdrawal from
nicotine dependence. Proceedings of the Committee on Problems of Drug Dependence. NIDA Research
Monograph, 49, 239-246.
25. Rawson, R.A., & Tennant, F.S. (1983). Five year follow-up of opiate addicts with naltrexone and behavior therapy.
Proceedings of the Committee on Problems of Drug Dependence. NIDA Research Monograph, 49, 289-295.
26. Tennant, F.S., Rawson, R.A., Miranda, L., & Obert, J. (1983). Outpatient treatment of prescription opioid
dependence: Comparison of two methods. Proceedings of the Committee on Problems of Drug Dependence.
NIDA Research Monograph, 43, 315-321.
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Richard A. Rawson, PhD
27. Tennant, F.S., Rawson, R.A., Cohen, A.M., Tarver, A., & Clabough, D. (1984). Methadone plasma levels and
persistent drug abuse in high dose maintenance patients. Proceedings of the Committee on Problems of Drug
Dependence. NIDA Research Monograph, 49, 262-265.
28. Rawson, R.A., Washton, A.M., Resnick, R.B., & Tennant, F.S. (1984). Clonidine hydrochloride detoxification
from methadone treatment: The value of naltrexone aftercare. Advances in Drug and Alcohol Dependence, 3, 41-
49.
29. Tennant, F.S., Rawson, R.A., Cohen, A.M., & Mann, A.J. (1984). Clinical experience with naltrexone in suburban
opioid addicts. Journal of Clinical Psychiatry, 45, 42-45.
30. Rawson, R.A., Obert, J.L., McCann, M.J., & Mann, A.J. (1985). Cocaine treatment outcome: Cocaine use
following inpatient, outpatient, and no treatment. Proceedings of the Committee on Problems of Drug Dependence.
NIDA Research Monograph, 67, 271-277.
31. Rawson, R.A. (1986). Relapse prevention programming in the treatment of opioid users. Substance Abuse Bulletin,
2, 1-5.
32. Tennant, F.S., Rawson, R.A., Pumphrey, E.A., & Secoff, R. (1986). Clinical experiences with 959 opioid-
dependent patients treated with levo-alpha-acetylmethadol (LAAM). Journal of Substance Abuse Treatment, 3,
195-202.
33. Baxter, L.R., Schwartz, J.M., Phelps, M.E., Mazziotta, J.C., Barrio, J., Rawson, R.A., Engel, J., Guze, B.H., Selin,
C., & Sumida, R. (1988). Localization of the neurochemical effects of cocaine and other stimulants in the human
brain. Journal of Clinical Psychiatry, 49, 23-26.
34. Rawson, R.A., Obert, J.L., McCann, M.J., Smith, D.P., & Ling, W. (1990). Neurobehavioral treatment for cocaine
dependency. Journal of Psychoactive Drugs, 22(2),159-171.
35. Rawson, R.A. (1990). Cut the crack: The policymakers guide to cocaine treatment. Policy Review Journal, 51, 10-
19.
36. Rawson, R.A., Obert, J.L., McCann, M.J., Castro, F.G., & Ling, W. (1991). Cocaine abuse treatment: A review of
current strategies. Journal of Substance Abuse, 3, 457-491.
37. Rawson, R.A., Obert, J.L., McCann, M.J., & Ling, W. (1991). Psychological approaches for the treatment of
cocaine dependence: A neurobehavioral approach. Journal of Addictive Diseases, 11(2), 97-119.
38. Rawson, R.A., & Ling, W. (1991). Opiate addiction treatment modalities and some guidelines for their optimal use.
Journal of Psychoactive Drugs, 23(2), 151-163.
39. Rawson, R.A., Obert, J.L., McCann, M.J., Marinelli-Casey, P., & Suti, E. (1991). Outpatient chemical dependency
treatment and the managed care system: An unrealized symbiosis. Journal of Ambulatory Care Management,
14(4), 48-59.
40. Rawson, R.A. (1990-1991). Chemical dependency treatment: The integration of the alcoholism and drug
addiction/use systems. International Journal of the Addictions, 25(12A), 1515-1536.
41. Castro, F.G., Sharp, E.V., Barrington, E.H., Walton, M., & Rawson, R.A. (1991). Drug abuse and identity in
Mexican Americans: Theoretical and empirical considerations. Hispanic Journal of Behavioral Sciences, 13(2),
209-225.
42. Castro, F.G., Barrington, E.H., Sharp, E.V., Dial, L.S., Wang, B., & Rawson, R.A. (1992). Behavioral and
psychological profiles of cocaine users upon treatment entry: Ethnic comparison. Drugs and Society, 6, 231-251.
43. Ling, W., & Rawson, R.A. (1993). American opiate substitution treatment programs: From methadone to LAAM
and Buprenorphine. Proceedings of the Swiss Services Project for the Medical Prescription of Narcotics. Thun,
Switzerland.
44. Rawson, R.A., Obert, J.L., McCann, M.J., & Marinelli-Casey, P. (1993). Relapse prevention models for substance
abuse treatment. Psychotherapy, 30(2), 284-298.
45. Rawson, R.A., Obert, J.L., McCann, M.J., & Marinelli-Casey, P. (1993). Relapse prevention strategies in outpatient
substance abuse treatment. Psychology of Addictive Behaviors, 7(2), 85-95.
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Richard A. Rawson, PhD
46. Rawson, R.A., Obert, J.L., McCann, M.J., & Ling, W. (1993). Neurobehavioral treatment for cocaine dependency:
A preliminary evaluation. NIDA Research Monograph, 135, 92-115.
47. Harvey, E.M., Rawson, R.A., & Obert, J.L. (1994). History of sexual assault and the treatment of substance abuse
disorders. Journal of Psychoactive Drugs, 26(4), 361-367.
48. Shoptaw, S., Rawson, R.A., McCann, M.J., & Obert, J.L. (1994). The Matrix Model of outpatient stimulant abuse
treatment: Evidence of efficacy. Journal of Addictive Diseases, 13(4), 129-141.
49. Harvey, E.M., Rawson, R.A., Alexander, E., & Bacher, K. (1994). Binge eating in males: A sample description
and treatment outcomes study. Eating disorders: Journal of Treatment and Prevention, 2(3), 215-230.
50. Grella, C.E., Anglin, M.D., Wugalter, S.E., Rawson, R.A., & Hasson, A. (1994). Reasons for discharge from
methadone maintenance for addicts at high risk of HIV infection or transmission. Journal of Psychoactive Drugs,
26(2), 223-232.
51. Ling, W., Rawson, R.A., & Compton, M.A. (1994). Substitution pharmacotherapies for opiate addiction: From
methadone to LAAM and buprenorphine. Journal of Psychoactive Drugs, 26(2), 119-127.
52. Rawson, R.A., McCann, M.J., Hasson, A., & Ling, W. (1994). Cocaine abuse among methadone maintenance
patients: Are there effective treatment strategies? Journal of Psychoactive Drugs, 26(2), 129-136.
53. Hasson, A.L., Grella, C.E., & Rawson, R.A. (1994). Case management within a methadone maintenance program:
A research demonstration project for HIV risk reduction. Journal of Case Management, 3(4), 167-172.
54. Rawson, R.A., Shoptaw, S.J., Obert, J.L., McCann, M.J., Hasson, A.L., Marinelli-Casey, P.J., Brethen, P.R., &
Ling, W. (1995). An intensive outpatient approach for cocaine abuse treatment: The Matrix Model. The Journal
of Substance Abuse Treatment, 12(2), 117-127
55. Frosch, D., Shoptaw, S., Huber, A., Rawson, R.A., & Ling, W. (1996). Sexual HIV risk among gay and bisexual
male methamphetamine users. Journal of Substance Abuse Treatment, 13(6), 483-486. PMID: 9219145
56. McCann, M.J., Miotto, K., Rawson, R.A., Huber, A., Shoptaw, S., & Ling, W. (1996). Outpatient non-opioid
detoxification for opioid withdrawal: Who is likely to benefit? American Journal on Addictions, 6(3), 218-223.
57. Shoptaw, S., Jarvik, M.E., Ling, W., & Rawson, R.A. (1996). Contingency management for tobacco smoking in
methadone maintained opiate addicts. Addictive Behaviors, 21(3), 409-412.
58. Grella, C.E., Anglin, A.D., Rawson, R.A., Crowley, R., & Hasson, A. (1996). What happens when a demonstration
project ends: Consequences for a clinic and its clients. Journal of Substance Abuse Treatment, 13(3), 249-256.
59. Johnson, B.A., Jasinski, D.R., Galloway, G., Kranzler, H., Weinrieb, R., Anton, R.F., Mason, B.J., Bohn, M.J.,
Pettinatti, H.M., Rawson, R.A., & Clyde, C. (1996). Ritanserin in the treatment of alcohol dependence: A multi-
center clinical trial. Psychopharmacology, 128, 206-215.
60. Shoptaw, S., Frosch, D., Rawson, R.A., & Ling, W. (1997). Cocaine abuse counseling as HIV prevention. AIDS
Education and Prevention, 9(6), 511-520. PMID 9451479
61. Obert, J.L., Rawson, R.A., & Miotto, K. (1997). Substance abuse treatment for "hazardous users": An early
intervention. Journal of Psychoactive Drugs, 29, 291-298.
62. Miotto K., McCann M.J., Rawson R.A., Frosch D., Ling W. (1997). Overdose, suicide attempts and death among
a cohort of naltrexone-treated opioid addicts. Drug and Alcohol Dependence, 45, 131-134.
63. Huber, A., Ling, W.L., Shoptaw, S., Gulati, V., Brethen, P, & Rawson, R. (1997). Integrating treatments for
methamphetamine abuse: A psychosocial perspective. Journal of Addictive Diseases, 16(4), 41-50.
64. Frosch D., Shoptaw, S., Jarvik, M.E., Rawson, R.A., & Ling, W. (1998). Interest in smoking cessation among
methadone maintained outpatients. Journal of Addictive Diseases, 17(2), 9-19.
65. Ling, W., Shoptaw, S., Wesson, D., Rawson, R.A., Compton, M., & Klett, C.J. (1998). Treatment effectiveness
score as an outcome measure in clinical trials. NIDA Research Monograph, 175, 208-220.
66. Rawson, R., Hasson, A., Huber, A., McCann, M., & Ling, W. (1998). A 3-year progress report on the
implementation of LAAM in the United States. Addiction, 93(4), 533-540.
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67. Shoptaw, S., Reback, C.J., Frosch, D.L., & Rawson, R.A. (1998). Stimulant abuse treatment as HIV prevention.
Journal of Addictive Diseases, 17(4), 19-32.
68. Gonzalez Castro, F., Barrington, E.H., Walton, M.A. & Rawson, R.A. (2000). Cocaine and methamphetamine:
Differential addiction rates. Psychology of Addictive Behaviors, 14(4), 390-396.
69. Rawson, R.A., McCann, M.J., Hasson, A., & Ling, W. (2000). Addiction pharmacotherapy 2000: New options
and new challenges. Journal of Psychoactive Drugs, 32, 371-378.
70. Domier, C.P., Simon, S.L., Rawson, R.A., Huber, A., & Ling, W. (2000). A comparison of injecting non-
injecting methamphetamine users. Journal of Psychoactive Drugs, 32, 229-232.
71. Huber, A., Lord, R., Gulati, V., Marinelli-Casey, P., Rawson, R. & Ling, W. (2000). The CSAT
Methamphetamine Treatment Project: Research design accommodations for “real world” application. Journal
of Psychoactive Drugs, 32, 149-156.
72. Rawson, R.A., Huber, A., Brethen, P.B., Obert, J.L., Gulati, V., Shoptaw, S., & Ling,W. (2000).
Methamphetamine and cocaine users: Differences in characteristics and treatment retention. Journal of
Psychoactive Drugs, 32, 233-238.
73. Anglin, M.D., & Rawson, R.A. (2000). The CSAT Methamphetamine Treatment Project: What are we trying to
accomplish? Journal of Psychoactive Drugs, 32, 209-210.
74. Rawson, R.A., McCann, M.J, Huber, A., Marinelli-Casey, P., & Williams, L. (2000). Moving research into
community settings in the CSAT Methamphetamine Treatment Project: The coordinating center perspective.
Journal of Psychoactive Drugs, 32(2), 201-208.
75. Shoptaw, S., Stein, J., & Rawson, R.A. (2000). Burnout in substance abuse counselors: Impact of environment,
attitudes and clients with HIV. Journal of Substance Abuse Treatment, 19, 117-126.
76. Obert, J.L., McCann, M.J., Marinelli-Casey, P., Weiner, A., Minsky, S., Brethen, P., & Rawson, R.A. (2000).
The Matrix Model of outpatient substance abuse treatment: History and description. Journal of Psychoactive
Drugs, 32(2), 157-164.
77. Simon, S.L., Domier, C., Carnell, J., Brethen, P., Rawson, R.A., & Ling, W. (2000). Cognitive impairment in
individuals currently using methamphetamine. American Journal on Addictions, 9(3), 222-231.
78. Blackwell, B., Nace, D., Rawson, R., Greenberg, P., Shaffer, I., Rofman, E.S., Callahan, J., Mee-Lee, D., Kasser,
C., Miller, M.M., & Radcliffe, A. (2000.) Practice guidelines: An ASAM-AMBHA joint statement. Journal of
Addictive Diseases, 19(2), 117-119.
79. Anglin, M.D., & Rawson, R.A. (Eds.) (2000). The CSAT Methamphetamine Treatment Project: Moving
research into the “real world.” Journal of Psychoactive Drugs, 32(2), 135-136.
80. Rawson, R.A., McCann, M.J., Shoptaw, S., Miotto, K., Frosch, D.L., Obert, J.L., & Ling, W. (2001). Naltrexone
for opiate addiction: Evaluation of a manualized psychosocial protocol to enhance treatment response. Drug and
Alcohol Review, 20, 67-80.
81. Ling, W., Huber, A., & Rawson, R.A. (2001). New trends in opiate pharmacotherapy: A review. . Drug and
Alcohol Review, 20, 51-68.
82. Isralowitz, R., Sussman, G., Afifi, M. Rawson, R., Babor, T., & Monteiro, M. (2001). Substance abuse policy
and peace in the Middle East: A Palestinian and Israeli Partnership. Addiction, 96, 973-980
83. Burden, W., Prendergast, M., Roll, J., & Rawson, R.A. (2001). The role of contingency management in drug
courts. Journal of Drug Issues, 31, 73-90.
84. Sim, T., Simon, S., Domier, C.P., Richardson, K., Rawson, R.A., & Ling, W. (2002). Cognitive deficits among
methamphetamine users with attention deficit hyperactivity disorder symptomatology. Journal of Addictive
Diseases, 21(1), 75-89.
85. Simon, S.L., Richardson, K., Dacey, J., Glynn, S., Domier, C., Rawson, R.A., & Ling, W. (2002). A comparison
of patterns of methamphetamine and cocaine use. Journal of Addictive Diseases, 21(1), 35-44.
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86. Rawson, R.A., Huber, A., Brethen, P., Obert, J.L., Gulati, V., Shoptaw, S., & Ling, W. (2002). Status of
methamphetamine users 2-5 years after outpatient treatment. Journal of Addictive Diseases 21, 107-119.
87. Rawson, R.A., Anglin, M.D., & Ling, W. (2002). Will the methamphetamine problem go away? Journal of
Addictive Diseases 21, 5-19.
88. Miotto, K., McCann, M.J., Basch, J., Rawson, R.A., & Ling, W. (2002) Naltrexone and dysphoria: Fact or
myth? American Journal on Addictions, 11(2), 151-160.
89. Marinelli-Casey, P.J., Domier, C. & Rawson, R.A. (2002). The gap between research and practice in substance
abuse treatment. Psychiatric Services 53(8), 984-987.
90. Rawson, R.A., Washton, A.M., Domier, C.P., & Reiber, C. (2002). Drugs and sexual effects: Role of drug type
and gender. Journal of Substance Abuse Treatment 22(2), 103-108.
91. Shoptaw, S., Rotheram-Fuller, E., Yang, X., Frosch, D., Nahom, D., Jarvik, M.E., Rawson, R.A., & Ling, W.
(2002). Smoking cessation in methadone maintenance. Addiction, 97(10), 1317-1328.
92. Reiber, C., Ramirez, A., Parent, D., & Rawson, R.A. (2002). Predicting treatment success at multiple timepoints
in diverse patient populations of cocaine dependent individuals. Drug and Alcohol Dependence, 68, 35-48.
93. McNeese-Smith, D., Crook M.W., Marinelli-Casey, P., Williams, L., & Rawson, R. (2002). Benefit
determination under managed care for substance abuse treatment clients. Care Management Journals, 3, 55-62.
94. Rawson, R.A., Marinelli-Casey, P., & Ling, W. (2002). Dancing with strangers: Will U.S. substance abuse
practice and research organizations build mutually productive relationships? Addictive Behaviors, 27(6), 941-
950.
95. Rawson, R.A., Gonzales, R.G., & Brethen, P. (2002). Methamphetamine: Current research findings and clinical
challenges. Journal of Substance Abuse Treatment 23, 145-150.
96. Rawson, R.A., & Stein, J. (2002). Blending clinical practice and research: Forging partnerships to enhance drug
addiction treatment. Journal of Substance Abuse Treatment, 23, 67-68.
97. Spear, S., & Rawson, R.A. (2002). Linking substance abuse researchers and practitioners in the substance abuse
field: Perspectives of two bridgers. Journal of Drug Issues, 32, 881-892.
98. Rawson, R.A. & Branch, C. (2002). Connecting substance abuse treatment and research: “Let’s make a deal.”
Journal of Drug Issues, 32, 769-782.
99. Crevecoeur, D., Finnerty, B., & Rawson, R. (2002) The Los Angeles County Evaluation System (LACES): A
large scale substance abuse treatment system evaluation program. Journal of Drug Issues, 32, 865-880.
100. Spear, S.A., & Rawson, R.A. (2002). Preface: Perspectives from the conference, “Common Ground, Common
Goals, Common Language: Bringing Substance Abuse Practice and Research Together. Journal of Drug
Issues, 32, 751-756.
101. Obert, J.L., London, E.D., & Rawson, R.A (2002). Incorporating brain research findings into standard treatment:
An example using the Matrix Model. Journal of Substance Abuse Treatment, 23, 107-114.
102. Foreman, R., Dackis, C., & Rawson, R. (2002). Substance abuse: Twelve principles to more effective outpatient
treatment. Current Psychiatry, 1, 16-24.
103. Rawson, R.A., Marinelli-Casey, P., & Huber, A. (2002). Treating methamphetamine dependence in adults. In
R. Straw & J.M. Herrell (Eds.), Conducting multiple site evaluations in real world settings. New Directions in
Evaluation, 94, 73-87.
104. Farabee, D., Rawson, R.A., & McCann, M. (2002). Adoption of drug avoidance activities among patients in
contingency management and cognitive-behavioral treatments. Journal of Substance Abuse Treatment, 23, 343-
350.
105. Rawson, R.A., Huber, A., McCann, M.J, Shoptaw, S., Farabee, D., Reiber, C., & Ling, W. (2002). A comparison
of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for
cocaine dependence. Archives of General Psychiatry, 59(9), 817-824.
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106. Miotto, K., Darakjian, J., Basch, J., Murray, S., Zogg, J., & Rawson, R.A. (2002). Gamma-hydroxybutric Acid
(GHB): Patterns of use, effects and withdrawal. American Journal on Addictions, 10(3), 232-241.
107. Stizer, M.L., Owen, P.L., Hall, S.M., Rawson, R.A., & Petry, N.M. (2003). CPDD policy statement. Standards
for drug abuse treatment providers. Drug and Alcohol Dependence, 71, 213-215.
108. Messina, N., Farabee, D., & Rawson, R. (2003). Treatment responsivity of cocaine-dependent patients with
antisocial personality disorder in cognitive behavioral and contingency management interventions. Journal of
Consulting and Clinical Psychology, 71,320-329.
109. McNeese-Smith, D.K., Crook, M.W., Marinelli-Casey, P., & Rawson, R.A. (2003). Processes and outcomes of
substance abuse treatment within managed care: A preliminary report. Journal of Addictions Nursing, 14, 65-
73.
110. Ling, W., Rawson, R.A., & Compton, M. (2003). Clinical treatment of opioid addiction and dependence.
Methods in Molecular Medicine, 84, 285-295.
111. Watson, D.W., Rawson, R.A., Rataemane, S., Shafer, M.S., Obert, J.L., Bisesi, L., Tanamly, S. (2004). A
distance education model for teaching substance abuse providers in cognitive behavioral therapy. Journal of
Teaching in the Addictions, 2, 45-57.
112. Simon, S.L., Dacey, J., Glynn, S. , Rawson, R.A., & Ling, W. (2004). The effect of relapse on cognition in
abstinent methamphetamine users. Journal of Substance Abuse Treatment, 27, 59-66.
113. Rawson, R.A., Marinelli-Casey, P., Anglin, M.D., Dickow, A., Frazier, Y., Gallagher, C., Galloway, G.P.,
Herrell, J., Huber, A., McCann, M.J., Obert, J., Pennell, S., Reiber, C., Vandersloot, D., Zweben, J., and the
Methamphetamine Treatment Project Corporate Authors. (2004). A multi-site comparison of psychosocial
approaches for the treatment of methamphetamine dependence. Addiction, 99, 708-717.
114. Ling, W., Cunningham-Rathner, J., & Rawson, R.A. (2004). Diffusion of substance abuse treatment: Will
buprenorphine be a success? Journal of Psychoactive Drugs, May(Suppl. 2), 115-117.
115. London, E.D., Simon, S.L., Berman, S.M., Mandelkern, M.A., Lichtman, A.M., Bramen, J., Shinn, A.K., Miotto,
K., Learn, J., Dong, Y., Matochik, J.A., Kurian, V., Newton, T., Woods, R., Rawson, R.A., & Ling, W.L. (2004).
Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine
abusers. Archives of General Psychiatry, 61,73-84.
116. Shoptaw, S., Watson, D.W., Reiber, C., Rawson, R.A., Montgomery, M.A., Majewska, M.D., & Ling, W.
(2005). Randomized controlled pilot trial of cabergoline, hydergine and levodopa/carbidopa: Los Angeles
Cocaine Rapid Efficacy Screening Trial (CREST). Addiction, 100(Suppl. 1), 78-90.
117. Brown, A.H., Domier, C., & Rawson, R. (2005). Stimulants, sex, and gender. Sexual Addiction and
Compulsivity, 12, 169-180.
118. Longshore, D., Anglin, D., Annon, J., & Rawson, R.A. (2005). Levo-alpha-acetylmethyadol (LAAM) vs
methadone: Treatment retention and opiate use. Addiction. 100, 1131-1139
119. London, E.D., Berman, S., Voytek, B., Simon, S.L., Mandelkern, M.A., Monterrosso, J., Thompson, P., Brody,
A., Gaega, J., Hong, M., Hayashi, K., Rawson, R.A., & Ling, W. (2005). Cerebral metabolic dysfunction and
impaired vigilance in recently abstinent methamphetamine users. Biological Psychiatry, 58, 770-778.
120. Spear, S., Hamilton, A., & Rawson, RA. (2005). Painting a picture of the client: Implementing the ASI in
community treatment programs. Journal of Substance Abuse Treatment, 29, 277-282.
121. Rawson, R.A., Gonzales, R., Obert, J.L., McCann, M.J., & Brethen, P. (2005). Methamphetamine use among
treatment-seeking adolescents in Southern California: Participant characteristics and treatment response.
Journal of Substance Abuse Treatment, 29(2), 67-74.
122. Rawson, R.A., McCann, M.J., Flammino, F., Shoptaw, S., Miotto, K., Reiber, C., & Ling, W. (2006). A
comparison of contingency management and cognitive-behavioral approaches for stimulant-dependent
individuals. Addiction, 101(2), 267-74.
123. Hser, Y.I., Stark, M.E., Paredes, A., Huang, D., Anglin, M.D., & Rawson, R.A. (2006). A 12-year follow-up of
a treated cocaine-dependent sample. Journal of Substance Abuse Treatment, 30, 219-226.
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124. Isralowitz, R., & Rawson, R. (2006). Gender differences in prevalence of drug use among high risk adolescents
in Israel. Addictive Behaviors, 31, 355-358.
125. Rawson, R.A., Gonzales, R., & Ling, W. (2006) Methamphetamine abuse and dependence: An update. New
Directions in Psychiatry, 26, 221-236.
126. Gonzales, R.G., Marinelli-Casey, P.M., Shoptaw, S., Ang, A., & Rawson, R.A. (2006). Hepatitis C virus
infection among methamphetamine dependent individuals in outpatient treatment. Journal of Substance Abuse
Treatment, 31, 195-202.
127. Venneman, S., Leuchter, A., Bartzokis, G., Beckson, M., Simon, S.L., Schaefer, M., Rawson, R., Newton, T.,
Cook, I.A., Uijtdehaage, S., & Ling W. (2006). Variation in neurophysiological function and evidence of
quantitative electroencephalogram discordance: Predicting cocaine-dependent treatment attrition. Journal of
Neuropsychiatry and Clinical Neuroscience, 18, 208-216.
128. Ling, W., Rawson, R.A., & Shoptaw, S. (2006) Management of methamphetamine abuse and dependence.
Current Psychiatry Reports, 8, 345-354.
129. Anglin, M.D., Urada, D., Brecht, M.L., Hawken, A., Rawson, R., & Longshore, D. (2007). Criminal justice
treatment admissions for methamphetamine use in California: A focus on Proposition 36. Journal of
Psychoactive Drugs, Suppl. 4, 367-381.
130. Castro, F., Rawson, R.A., & Stamper, E. (2007). Response: TIPsters weigh in: Putting good science to work.
Science & Practice Perspectives, 3(2),35-36. PMCID: PMC2851078
131. Spear, S., Crèvecoeur, D.A., Rawson, R.A., & Clark, R. (2007). The rise in methamphetamine use among
American Indians in Los Angeles County. American Indian and Alaska Native Mental Health Research, 14(2),
1-15.
132. Rawson, R.A., & Rutkowski, B.A. (2007, October 11). Prime numbers: A matter of life or meth. Foreign Policy,
163, 32-33.
133. Rawson, R.A., & Condon, T., (2007). Why do we need a special issue of Addiction focused on
methamphetamine? Addiction, 102, 1-4.
134. Rutkowski, B., Freese, T., & Rawson, R. (2007). Editors’ introduction: California Substance Abuse Research
Consortium 2006. Journal of Psychoactive Drugs, SARC Supplement 4, 309-311.
135. Rawson, R.A., Gonzales, R., McCann, M., & Ling, W. (2007). Use of methamphetamine by young people: Is
there reason for concern? Addiction, 102(7), 1021-1022.
136. Rawson, R., Gonzales, R., Marinelli-Casey, P., & Ang, A. (2007). Methamphetamine dependence: A closer look
at treatment response and clinical characteristics associated with route of administration in outpatient treatment.
American Journal on Addictions, 16(4), 291-299.
137. Rawson, R.A., Maxwell, J., & Rutkowski, B. (2007). OxyContin abuse: Who are the users? American Journal
of Psychiatry, 164(11), 1634-1636.
138. Messina, N., Farabee, D., & Rawson, R. (2007). Cocaine-dependent patients with antisocial personality disorder.
Journal of Drug Addiction, Education and Eradication, 3(1/2), 75-96.
139. Isralowitz, R., Reznik, A., Spear, S., Brecht, M.L., & Rawson, R.(2007) Severity of heroin use in Israel:
Comparisons between native Israelis and former Soviet Union immigrants. Addiction, 102, 630-637.
140. Hillhouse, M., Marinelli-Casey, P. Gonzales, R., Ang, A., & Rawson, R.A., & the Methamphetamine Treatment
Project Corporate Authors. (2007). Predicting in-treatment performance and post-treatment outcomes in
methamphetamine users. Addiction, 102, 84-95.
141. Elkashef, A.M., Rawson, R.A., Anderson, A.L., Li, S.-H., Holmes, T., Smith, E.V., Chiang, N., Kahn, R., Vocci,
F., Ling, W., Pearce, V.J., McCann, M., Campbell, J., Gorodetzky, C., Haning, W., Carlton, B., Mawhinney, J.,
& Weis, D. (2007). Buproprion for the treatment of methamphetamine dependence. Neuropsychopharmacology,
33(5), 1162-1170.
142. Elkashef, A., Rawson R.A., Smith, E., Pearce, V., Flammino, F., Campbell, J., Donovick, R. Gorodetsky, C.,
Haning, W., Mahwinney, J., McCann, M., Weis, D., Williams, L., Ling, W., & Vocci, F. (2007). The NIDA
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Methamphetamine Clinical Trials Group: A strategy to increase clinical trials research capacity. Addiction, 102,
107-113.
143. Crevecoeur, D., Rutkowski, B., & Rawson, R. (2007). The rise in treatment admissions for methamphetamine
use in Los Angeles County from 2001 through 2005. Journal of Psychoactive Drugs, SARC Supplement 4, 383-
392.]
144. Rawson, R., Gonzales, R., Pearce, V., Ang, A., Marinelli-Casey, P., Brummer, J., and the Methamphetamine
Treatment Project Corporate Authors. (2008). Methamphetamine dependence and human immunodeficiency
virus. Journal of Substance Abuse Treatment, 35, 279-284. PMCID: PMC2630179
145. Messina, N., Marinelli-Casey, P., Hillhouse, M., Hunter, J., & Rawson, R. (2008). Childhood adverse events
and health outcomes among methamphetamine-dependent men and women. International Journal of Mental
Health and Addiction, 6(4), 522-536.
146. Marinelli-Casey, P., Gonzales, R., Hillhouse, M., Ang, A., Zweben, J., Cohen, J., Fulton Hora P., Rawson, R.A.,
and the Methamphetamine Treatment Project Corporate Authors (2008). Drug court treatment for
methamphetamine dependence: Treatment response and post-treatment outcomes. Journal of Substance Abuse
Treatment, 34(2), 242-248. PMID: 17596903
147. Gonzales, R., Ang, A., McCann, M., & Rawson, R. (2008). An emerging problem: Methamphetamine use among
treatment seeking youth. Substance Abuse, 29(2), 71-80. PMID: 19042326
148. Lee, N.K., & Rawson, R.A. (2008). A systematic review of cognitive and behavioural therapies for
methamphetamine dependence. Drug and Alcohol Review, 27(3), 309-317. PMCID: PMC 4445690
149. Khalil, A., Okasha, T., Shawky, M., Haroon, A, Elhabiby, M., Carise, D., Annon, J.J., Hasson, A.M., Rawson,
R.A. (2008). Characterization of substance abuse patients presenting for treatment at a university psychiatric
hospital in Cairo, Egypt. Addictive Disorders and Their Treatment, 7(4), 199-209.
150. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., & Rawson, R.; the
Methamphetamine Treatment Project Corporate Authors. (2008). Identifying methamphetamine users at risk for
major depressive disorder: Findings from the Methamphetamine Treatment Project at three-year follow-up.
American Journal on Addictions, 17(2), 99-102. PMID: 18393051
151. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., & Rawson, R., the
Methamphetamine Treatment Project Corporate Authors. (2008). Risk factors for suicide attempts in
methamphetamine-dependent patients. American Journal on Addictions, 17(1), 24-27. PMID: 18214719
152. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., Rawson, R.; the
Methamphetamine Treatment Project Corporate Authors. (2008). Clinical course and outcomes of
methamphetamine-dependent adults with psychosis. Journal of Substance Abuse Treatment, 35(4), 445-450.
PMID: 18294802
153. Messina, N., Marinelli-Casey, P., Hillhouse, M., Rawson, R., Hunter, J., & Ang, A. (2008). Childhood adverse
events and methamphetamine use among men and women. The Journal of Psychoactive Drugs, Suppl. 5, 399-
409. PMID: 19248397
154. Rutkowski, B., Freese, T., & Rawson, R. (2008). Editors' introduction: California Substance Abuse Research
Consortium, 2007: A focus on women. Journal of Psychoactive Drugs, Suppl. 5, 321-323. PMID: 19248391
155. Glasner-Edwards, S., Marinelli-Casey, P., Hillhouse, M., Ang, A., Mooney, L.J., & Rawson, R.;
Methamphetamine Treatment Project Corporate Authors. (2009). Depression among methamphetamine users:
Association with outcomes from the Methamphetamine Treatment Project at 3-year follow-up. Journal of
Nervous and Mental Disease, 197(4), 225-231. PMCID: PMC2749575
156. Gonzales, R., Ang, A., Marinelli-Casey, P., Glik, D.C., Iguchi, M.Y., & Rawson, R.A.; Methamphetamine
Treatment Project Corporate Authors. (2009). Health-related quality of life trajectories of methamphetamine-
dependent individuals as a function of treatment completion and continued care over a 1-year period. Journal of
Substance Abuse Treatment, 37(4), 353-361. PMID: 19553066
157. Roll, J.M., Madden, G.J., Rawson, R., & Petry, N.M. (2009). Facilitating the adoption of contingency
management for the treatment of substance use disorders. Behavior Analysis in Practice, 2(1), 4-13. PMCID:
PMC2854061
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158. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., Rawson, R.A., & the
Methamphetamine Treatment Project Corporate Authors. (2009). Psychopathology in methamphetamine-
dependent adults 3 years after treatment. Drug and Alcohol Review, 29, 12-20. PMID: 20078677 NIHMSID
475182
159. Mooney, L.J., Glasner-Edwards, S., Marinelli-Casey, P., Hillhouse, M., Ang, A., Hunter, J., Haning, B.,
Colescott, P, Ling, W., & Rawson, R.A. (2009). Health conditions in methamphetamine-dependent adults 3
years after treatment. Journal of Addiction Medicine, 3(3), 155-163. PMID: 21769012
160. Spear, S., Tillman, S., Moss, C., Gong-Guy, E., Ransom, L., & Rawson, R.A. (2009). Another way of talking
about substance abuse: Substance abuse screening and brief intervention in a mental health clinic. Journal of
Human Behavior in the Social Environment, 19, 959-977. PMCID: PMC3137280
161. Hasan, N.M., Loza, N., El-Dosoky, A., Hamdi, N., Rawson, R., Hasson, A.L., Shawky, M.M. (2009).
Characteristics of clients with substance abuse disorders in a private hospital in Cairo, Egypt. Journal of Muslim
Mental Health, 4(1), 9-15.
162. Sodano, R., Watson, D.W., Rataemane, S., Rataemane, L., Ntlhe, N., & Rawson, R. (2010). The substance
abuse treatment workforce of South Africa. International Journal of Mental Health and Addiction, 8(4), 608-
615. PMCID: PMC2965395
163. Shetty, V., Mooney, L.J., Zigler, C.M., Belin, T.R., Murphy, D., & Rawson, R. (2010). The relationship between
methamphetamine use and increased dental disease. Journal of the American Dental Association, 141, 307-318.
PMCID: PMC2947197
164. Gonzales, R., Mooney, L., & Rawson, R.A. (2010). The methamphetamine problem in the United States. Annual
Review of Public Health, 31, 6.1-6.14. PMCID: PMC4440680
165. Rutkowski, B.A., Gallon, S., Rawson, R.A., Freese, T.E., Bruehl, A., Crèvecoeur-Macphail, D., Sugita, W.,
Molfenter, T., & Cotter, F. (2010). Improving client engagement and retention in treatment: The Los Angeles
County experience. Journal of Substance Abuse Treatment, 39, 78-86. PMID: 20409672
166. Rawson, R.A., & Gonzales, R. (2010). Commentary on Marshall et al. (2010): Are long-term negative health
consequences of methamphetamine use important to youth? Addiction, 105, 1003-1004. PMCID: PMC4074535
167. Glasner-Edwards, S., & Rawson, R. (2010). Evidence-based practices in addiction treatment: Review and
recommendations for public policy. Health Policy, 97, 93-104. PMCID: PMC2951979
168. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., & Rawson, R.;
Methamphetamine Treatment Project Corporate Authors. (2010). Anxiety disorders among methamphetamine
dependent adults: Association with post-treatment functioning. American Journal on Addictions, 19(5), 385-
390. PMCID: PMC3159418
169. Momtazi, S., & Rawson, R. (2010). Substance abuse among Iranian high school students. Current Opinion in
Psychiatry, 23, 221-226. PMCID: PMC4479403
170. Zorick, T., Nestor, L., Miotto, K., Sugar, C., Hellemann, G., Scanlon, G., Rawson, R., & London, E.D. (2010).
Withdrawal symptoms in abstinent methamphetamine-dependent subjects. Addiction, 105(10), 1809-1818.
PMCID: PMC3071736
171. Crèvecoeur-MacPhail, D., Bellows, A., Rutkowski, B.A., Ransom, L., Myers, A.C., & Rawson, R.A. (2010).
“I’ve been NIATxed”: Participants’ experience with process improvement. Journal of Psychoactive Drugs,
SARC Supplement 6, 249-259. PMID: 21138201
172. Crèvecoeur-MacPhail, D., Ransom, L., Myers, A.C., Annon, J.J., Diep, N., Gonzales, R., Rawson, R.A., Viernes,
J., Jr., Sugita, W., & Barger, J. (2010). Inside the black box: Measuring addiction treatment services and their
relation to outcomes. Journal of Psychoactive Drugs, SARC Supplement 6, 269-276. PMID: 21138203
173. Davoudi, M., & Rawson, R.A. (2010). Screening, brief intervention, and referral to treatment (SBIRT) initiatives
in California: Notable trends, challenges, and recommendations. Journal of Psychoactive Drugs, SARC
Supplement 6, 239-248. PMID: 21138200
174. Herbeck, D.M., Gonzales, R., & Rawson, R.A. (2010). Performance improvement in addiction treatment: Efforts
in California. Journal of Psychoactive Drugs, SARC Supplement 6, 261-268. PMID: 21138202
175. Tomás-Rosselló, J., Rawson, R.A., Zarza, M.J., Bellows, A., Busse, A., Saenz, E., Freese, T., Shawkey, M.,
Carise, D., Ali, R., & Ling, W. (2010). United Nations Office on Drugs and Crime International Network of
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Drug Dependence Treatment and Rehabilitation Resources Centres: Treatnet. Substance Abuse, 31, 251-263.
PMID: 21038179
176. Galloway, G.P., Singleton, E.G., Buscemi, R., Baggott, M.J., Dickerhoof, R.M., Mendelson, J.E.;
Methamphetamine Treatment Project Corporate Authors. (2010). An examination of drug craving over time in
abstinent methamphetamine users. American Journal on Addictions, 19(6), 510-514. doi: 10.1111/j.1521-
0391.2010.00082.x. PubMed PMID: 20958846. NIHMS228815
177. Rawson, R.A., Gonzales, R., Crèvecoeur-MacPhail, D., Urada, D., Brecht, M.-L., Chalk, M., Kemp, J., &
Cunningham, M. (2011). Improving the accountability of California’s public substance abuse treatment system
through the implementation of performance models. Journal of Psychoactive Drugs, 42(SARC Suppl. 6), 211-
214. PMID: 21138197
178. Rutkowski, B.A., Rawson, R.A., & Freese, T.E. (2011). Editors’ introduction: Improving the addiction treatment
system in California through the use of data and evidence-based practices – California Substance Abuse
Research Consortium (SARC) meetings, 2009. Journal of Psychoactive Drugs, 42(SARC Suppl. 6), 207-210.
PMID: 21138196
179. Glasner-Edwards, S., Mooney, L.J., Marinelli-Casey, P., Hillhouse, M., Ang, A., & Rawson, R.A. (2011).
Bulimia nervosa among methamphetamine dependent adults: Association with outcomes three years after
treatment. Eating Disorders: The Journal of Treatment and Prevention, 19(3), 259-269. PMCID: 3159413
180. Baser, O., Chalk, M., Rawson, R., & Gastfriend, D.R. (2011). Alcohol dependence treatments: Comprehensive
healthcare costs, utilization outcomes, and pharmacotherapy persistence. The American Journal of Managed
Care, 17(Suppl. 8), S222-S234. PMID: 21761948
181. Dickerson, D., Spear, S., Marinelli-Casey, P., Rawson, R.A., Li, L., & Hser, Y.-I. (2011). American
Indians/Alaska Natives and substance abuse treatment outcomes: Positive signs and continuing challenges.
Journal of Addictive Diseases, 30(1), 63-74. PMCID: PMC3042549
182. Gonzales, R., Brecht, M.-L., Mooney, L., & Rawson, R.A. (2011). Prescription and over-the-counter drug
treatment admissions to the California public treatment system. Journal of Substance Abuse Treatment, 40(3),
224-229. PMCID: PMC4018412
183. Gonzales, R., Ang, A., Glik, D.C., Rawson, R.A., Lee, S., Iguchi, M.Y.; Methamphetamine Treatment Project
Corporate Authors. (2011). Quality of life among treatment seeking methamphetamine-dependent individuals.
The American Journal on Addictions, 20(4), 366-372. PMCID: PMC4026308
184. Anderson, A.L., Li, S.-H., Biswas, K., McSherry, F., Holmes, T., Iturriaga, E., Kahn, R., Chiang, N., Beresford,
T., Campbell, J., Haning, W., Mawhinney, J., McCann, M., Rawson, R., Stock, C., Weis, D., Yu, E., & Elkashef,
A.M. (2012). Modafinil for the treatment of methamphetamine dependence. Drug and Alcohol Dependence,
120(1-3), 135-141. PMCID: PMC3227772
185. Elkashef, A., Kahn, R., Yu, E., Iturriaga, E., Li, S.-H., Anderson, A., Chiang, N., Ait-Daoud, N., Weiss, D.,
McSherry, F., Serpi, T., Rawson, R., Hrymoc, M., Weis, D., McCann, M., Pham, T., Stock, C., Dickinson, R.,
Campbell, J., Gorodetzky, C., Haning, W., Carlton, B., Mawhinney, J., Li, M.D., & Johnson, B.A. (2012).
Topiramate for the treatment of methamphetamine addiction: A multi-center placebo-controlled trial.
Addiction, 107(7), 1297-1306. PMCID: PMC3331916
186. Karno, M., Farabee, D., Brecht, M.L., & Rawson, R.A. (2012). Patient reactance moderates the effect of
directive telephone counseling for methamphetamine users. Journal of Studies on Alcohol and Drugs, 73, 844–
850. PMCID: PMC3410952
187. Farabee, D., Cousins, S.J., Brecht, M.-L., Antonini, V.P., Lee, A.B., Brummer, J., Hemberg, J., Karno, M., &
Rawson, R.A. (2012). A comparison of four telephone-based counseling styles for recovering stimulant users.
Psychology of Addictive Behavior, 27, 223-229. PMCID: PMC3500433
188. Urada, D., Schaper, E., Alvarez, L., Reilly, C., Dawar, M., Field, R., Antonini, V.P., Oeser, B.T., Crèvecoeur-
MacPhail, D., & Rawson, R.A. (2012). Perceptions of mental health and substance use disorder services
integration among the workforce in primary care settings. Journal of Psychoactive Drugs, 44(4), 292-298.
PMID: 23210377
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189. Padwa, H., Urada, D., Antonini, V.P., Ober, A., Crèvecoeur-MacPhail, D., & Rawson, R.A. (2012). Integrating
substance use disorder services with primary care: The experience in California. Journal of Psychoactive
Drugs, 44(4), 299-306. PMCID: PMC3664544
190. Cousins, S.J., Antonini, V.P., & Rawson, R.A. (2012). Utilization, measurement, and funding of recovery
supports and services in California. Journal of Psychoactive Drugs, 44(4), 325-333. PMID: 23210381
191. Rawson, R.A., Gonzales, R., Greenwell, L., & Chalk, M. (2012). Process-of-care measures as predictors of
client outcome among a methamphetamine-dependent sample at 12- and 36-month follow-ups. Journal of
Psychoactive Drugs, 44(4), 342-349. PMCID: PMC4018415
192. Rutkowski, B.A., Rawson, R.A., & Freese, T.E. (2012). Editors’ introduction: The evidence for integrated
care—substance use disorders, mental health and primary care: California Substance Abuse Research
Consortium (SARC) meetings, 2011. Journal of Psychoactive Drugs, 44(4), 281-284. PMID: 23210375
193. Evans, E., Pierce, J., Li, L., Rawson, R., & Hser, Y.I. (2012). More alike than different: Health needs, services
utilization, and outcomes of Asian American and Pacific Islander (AAPI) populations treated for substance use
disorders. Journal of Ethnicity in Substance Abuse, 11(4), 318-338. PMCID: PMC3526835
194. Dolezal, B.A., Chudzynski, J., Storer, T.W., Abrazado, M., Penate, J., Mooney, L., Dickerson, D., Rawson,
R.A., & Cooper, C.B. (2013). Eight weeks of exercise training improves fitness measures in
methamphetamine-dependent individuals in residential treatment. Journal of Addiction Medicine, 7(2), 122-
128. PMCID: PMC3617407
195. Rawson, R.A., Rataemane, S., Rataemane, L., Ntlhe, N., Fox, R.S., McCuller, J., & Brecht, M.-L. (2013).
Dissemination and implementation of cognitive behavioral therapy for stimulant dependence: A randomized
trial comparison of 3 approaches. Substance Abuse, 34(2), 108-117. PMCID: PMC3625982
196. Farabee, D., McCann, M., Brecht, M.-L, Cousins, S.J., Antonini, V.P., Lee, A.B., Hemberg, J., Karno, M., &
Rawson, R.A. (2013). An analysis of relapse prevention factors and their ability to predict sustained abstinence
following treatment completion. American Journal on Addictions, 22(3), 206-211. PMID: 23617860 doi:
10.1111/j.1521-0391.2012.00328.x. PMCID: PMC4437594
197. Ma, J.Z., Johnson, B.A., Yu, E., Weiss, D., McSherry, F., Saadvandi, J., Iturriaga, E., Ait-Daoud, N., Rawson,
R.A., Hrymoc, M., Campbell, J., Gorodetzky, C., Haning, W., Carlton, B., Mawhinney, J., Weis, D., McCann,
M., Pham, T., Stock, C., Dickinson, R., Elkashef, A., & Li, M.D. (2013). Fine-grain analysis of the treatment
effect of topiramate on methamphetamine addiction with latent variable analysis. Drug and Alcohol
Dependence, 130(1-3), 45-51. PMID: 23142494
198. Glasner-Edwards, S., Mooney, L., Ang, A., Hillhouse, M., & Rawson, R. (2013). Does posttraumatic stress
disorder (PTSD) affect post-treatment methamphetamine use? Journal of Dual Diagnosis, 9(2), 123-128.
doi:10.1080/15504263.2013.779157 PMCID: PMC3779468
199. Rawson, R.A. (2013). Current research on the epidemiology, medical and psychiatric effects, and treatment of
methamphetamine use. Journal of Food and Drug Analysis, 21(4), S77-S81. doi: 10.1016/j.jfda.2013.09.039
PMCID: PMC4158843
200. Hser, Y.-I., Chang, L., Wang, G.-J., Li, M.D., Rawson, R., Shoptaw, S., Normand, J., & Tai, B. (2013).
Capacity building and collaborative research on cross-national studies in the Asian region. Journal of Food
and Drug Analysis, 21(4), S117-S122. http://dx.doi.org/10.1016/j.jfda.2013.09.048 PMCID: PMC3931525
201. Giang, L.M., Ngoc, L.B., Hoang, V.H., Mulvey, K., & Rawson, R.A. (2013). Substance use disorders and
human immunodeficiency virus in Vietnam since Doi Moi (Renovation): An overview. Journal of Food and
Drug Analysis, 21(4), S42-S45. PMCID: PMC 4179236 http://dx.doi.org/10.1016/j.jfda.2013.09.032
202. Mooney, L.J., Cooper, C., London, E.D., Chudzynski, J., Dolezal, B., Dickerson, D., Brecht, M.-L., Peñate, J.,
& Rawson, R.A. (2013). Exercise for methamphetamine dependence: Rationale, design, and methodology.
Contemporary Clinical Trials, 37(1), 139-147. doi: 10.1016/j.cct.2013.11.010. PMCID: PMC4431553
203. Abolmaged, S., Kodera, A., Okasha, T., Gawad, T., & Rawson, R. (2013). Tramadol use in Egypt: Emergence
of a major new public health problem. Canadian Journal of Addiction Medicine, 4(1), 5.
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204. Dolezal, B.A., Chudzynski, J., Dickerson, D., Mooney, L., Rawson, R.A., Garfinkel, A., Cooper, C.B. (2014).
Exercise training improves heart rate variability after methamphetamine dependency. Medicine and Science in
Sports and Exercise, 46(6), 1057-1066. PMCID: PMC3999306
205. Urada, D., Teruya, C., Gelberg, L., & Rawson, R. (2014). Integration of substance use disorder services with
primary care: Health center surveys and qualitative interviews. Substance Abuse Treatment, Prevention, and
Policy, 9(1), 15. doi:10.1186/1747-597X-9-15 PMCID: PMCID 3978198
206. Rawson, R.A., Rieckmann, T., & Gust, S.W. (2014). Addiction science: A rationale and tools for a public
health response to drug abuse. Public Health Reviews, 35(2). http://www.publichealthreviews.eu/show/f/147
NIHMSID 644383
207. Al-Hemiary, N.J., Al-Diwan, J.K., Hasson, A.L., & Rawson, R.A. (2014). Drug and alcohol use in Iraq:
Findings of the inaugural Iraqi Community Epidemiological Workgroup. Substance Use & Misuse, 49(13),
1759-1763. DOI: 10.3109/10826084.2014.913633. PMCID: PMC4431571
208. Urada, D., Rawson, R.A., & Onuki, M. (2014). Peace building through a substance use conference structured
on peace psychology principles. Peace and Conflict: Journal of Peace Psychology, 20(1), 84-94.
http://dx.doi.org/10.1037/a0035579
209. Radfar, S.R., & Rawson, R.A. (2014). Current research on methamphetamine: Epidemiology, medical and
psychiatric effects, treatment, and harm reduction efforts. Addiction & Health, 6(3-4), 146-154.
http://ahj.kmu.ac.ir/index.php/ahj/article/view/187/229 PMCID: PMC4354220.
210. Nosyk, B., Li, L., Evans, E., Urada, D., Huang, D., Wood, E., Rawson, R., & Hser, Y.-I. (2014). Utilization
and outcomes of detoxification and maintenance treatment for opioid dependence in publicly-funded facilities
in California, US: 1991-2012. Drug and Alcohol Dependence, 143, 149-157. doi:
10.1016/j.drugalcdep.2014.07.020 PMCID: PMC4484858
211. Nosyk, B., Li, L., Evans, E., Urada, D., Huang, D., Wood, E., Rawson, R., & Hser, Y.-I. (2015). Erratum to
“Utilization and outcomes of detoxification and maintenance treatment for opioid dependence in publicly-
funded facilities in California, US: 1991–2012” [Drug Alcohol Depend. 143 (2014) 149–157]. Drug and
Alcohol Dependence, 148, 230-232. doi: http://dx.doi.org/10.1016/j.drugalcdep.2014.10.018
212. Radfar, S.R., Sedaghat, A., Banihashemi, A.T., Gouya, M., & Rawson, R.A. (2014). Behaviors influencing
human immunodeficiency virus transmission in the context of positive prevention among people living with
HIV/acquired immunodeficiency syndrome in Iran: A qualitative study. International Journal of Preventive
Medicine, 5(8), 976-983. PMCID: PMC4258663
213. Messina, N., Jeter, K., Marinelli-Casey, P., West, K., Rawson, R.A. (2014). Children exposed to
methamphetamine use and manufacture. Child Abuse & Neglect, 38(11), 1872-1883. doi:
10.1016/j.chiabu.2006.06.009. PMCID: PMC3029499
214. Rawson, R.A., Chudzynski, J., Gonzales, R., Mooney, L., Dickerson, D., Ang, A., Dolezal, B., & Cooper, C.B.
(2015). The impact of exercise on depression and anxiety symptoms among abstinent methamphetamine-
dependent individuals in a residential treatment setting. Journal of Substance Abuse Treatment, 57, 36-40.
doi:10.1016/j.jsat.2015.04.007. PMC4560957
215. Haglund, M., Ang, A., Mooney, L., Gonzales, R., Chudzynski, J., Cooper, C.B., Dolezal, B.A., Gitlin, M., &
Rawson, R.A. (2015). Predictors of depression outcomes among abstinent methamphetamine-dependent
individuals exposed to an exercise treatment. American Journal on Addictions, 24(3), 246-251. doi:
10.1111/ajad.12175.
216. Rawson, R.A., Woody, G., Kresina, T.F., & Gust, S. (2015). The globalization of addiction research: Capacity
building mechanisms and selected examples. Harvard Review of Psychiatry, 23(2), 147-156. PMCID:
PMC4356020 doi: 10.1097/HRP.0000000000000067
217. Rawson, R.A., Chudzynski, J., Mooney, L., Gonzales, R., Ang, A., Dickerson, D., Penate, J., Salem, B.A.,
Dolezal, B., & Cooper, C.B. (2015). Impact of an exercise intervention on methamphetamine use outcomes
post-residential treatment care. Drug and Alcohol Dependence, 156, 21-28. PMCID: PMC4633370. doi:
10.1016/j.drugalcdep.2015.08.029.
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218. Glasner-Edwards, S., Mooney, L., Ang., A., Garneau, H.C., Hartwell, E.E., Brecht, M.-L., Rawson, R.A.
(2015). Mindfulness based relapse prevention improves stimulant use among adults with major depression and
generalized anxiety disorder. Drug and Alcohol Dependence, 156, e80. doi:
http://dx.doi.org/10.1016/j.drugalcdep.2015.07.1135
219. Bart, G., Le, G.M., Nguyen, H., Tran, H., Rieckmann, T.R., Nguyen, S., Darfler, K., & Rawson, R.A. (2015).
Alcohol and drug use among patients receiving HIV services in Hanoi, Vietnam. Alcohol and Drug
Dependence, 156, e16.
220. Robertson, C.L., Ishibashi, K., Chudzynski, J., Mooney, L.J., Rawson, R.A., Dolezal, B.A., Cooper, C.B.,
Brown, A.K., Mandelkern, M.A., & London, E.D. (2016). Effect of exercise training on striatal dopamine
D2/D3 receptors in methamphetamine users during behavioral treatment. Neuropsychopharmacology, 41(6),
1629-1636. doi: 10.1038/npp.2015.331. PMCID: PMC4832026 [Available May 1, 2017]
221. Cousins, S.J. , Denering, L., Crèvecoeur-MacPhail, D., Viernes, J., Sugita, W., Barger, J., Kim, T., Weismann,
S., & Rawson, R.A. (2016). A demonstration project implementing extended-release naltrexone in Los
Angeles County. Substance Abuse, 37(1), 54-62. DOI: 10.1080/08897077.2015.1052868
222. Cousins, S.J., Radfar, S.R., Crèvecoeur-MacPhail, D., Ang, A., Darfler K., & Rawson, R.A. (2016). Predictors
of continued use of extended-release naltrexone (SR-NTX) for opioid dependence: An analysis of heroin and
non-heroin opioid users in Los Angeles County. Journal of Substance Abuse Treatment, 63, 66–71.
doi: http://dx.doi.org/10.1016/j.jsat.2015.12.004
223. Kohno, M., Okita, K., Morales, A.M., Robertson, C.L., Dean, A.C., Ghahremani, D.G., Saab, F.W., Rawson,
R.A., Mandelkern, M.A., Bilder, R.M., & London, E.D. (2016). Midbrain functional connectivity and ventral
striatal dopamine D2-type receptors: Link to impulsivity in methamphetamine users. Molecular Psychiatry.
doi: 10.1038/mp.2015.223 [Epub ahead of print]. PMCID: PMC4970974
224. Radfar, S.R., Cousins, S.J., Shariatirad, S., Noroozi, A., & Rawson, R.A. (2016). Methamphetamine use among
patients undergoing methadone maintenance treatment in Iran; a threat for harm reduction and treatment
strategies: A qualitative study. International Journal of High Risk Behaviors & Addiction.
doi: 10.5812/ijhrba.30327 [Epub ahead of print].
225. Glasner-Edwards, S., Patrick, K., Ybarra, M., Reback, C.J., Rawson, R.A, Chokron Garneau, H, Chavez, K., &
Venegas, A. (2016). A cognitive behavioral therapy-based text messaging intervention versus medical
management for HIV-infected substance users: Study protocol for a pilot randomized trial. JMIR Research
Protocols, 5(2), e131. PMCID: 4938885 doi: 10.2196/resprot.5407
226. Padwa, H., Urada, D., Gauthier, P., Rieckmann, T., Hurley, B., Crèvecoeur-MacPhail, D., & Rawson, R.A.
(2016). Organizing publicly funded substance use disorder treatment in the United States: Moving toward a
service system approach. Journal of Substance Abuse Treatment, 69, 9-18.
doi: http://dx.doi.org/10.1016/j.jsat.2016.06.010
227. Glasner-Edwards, S., Hartwell, E.E., Mooney, L., Ang, A., Garneau, H.C., Brecht, M.-L., & Rawson, R.A.
(2016). Changes in stress reactivity among stimulant dependent adults after treatment with mindfulness based
relapse prevention: Results from a pilot randomized clinical trial. Journal of Addiction Research & Therapy,
7:298. doi:10.4172/2155-6105.1000298
228. Miotto, K., Cho, A.K., Khalil, M.A., Blanco, K., Sasaki, J.D., & Rawson, R.A. (2017). Trends in tramadol:
Pharmacology, metabolism, and misuse. Anesthesia & Analgesia, 124(1), 44-51. doi:
10.1213/ANE.0000000000001683
229. Glasner-Edwards, S., Mooney, L.J., Ang, A., Garneau, H.C., Hartwell, E., Brecht, M.-L., & Rawson, R. A.
(2017). Mindfulness based relapse prevention for stimulant dependent adults: A pilot randomized clinical trial.
Mindfulness, 8(1), 126-135. doi:10.1007/s12671-016-0586-9. PMCID: PMC5300086 (Available Feb. 1,
2018).
230. Al-Hemiery, N., Dabbagh, R., Hashim, M.T., Al-Hasnawi, S., Abutiheen, A., Abdulghani, E.A., Al-Diwan,
J.K., Kak, N., Al Mossawi, H., Maxwell, J.C., Brecht, M.-L., Antonini, V., Hasson, A., & Rawson, R.A.
(2017). Self-reported substance use in Iraq: Findings from the Iraqi National Household Survey on Alcohol
and Drug Use, 2014. Addiction. [Epub ahead of print] doi: 10.1111/add.13800
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231. Rawson, R.A., & Clark, N. (2017). Interventions for the management of substance use disorders: An overview.
Eastern Mediterranean Health Journal, 23(3), 214-221.
232. Elkashef, A., Alhyas, L., Al Hashmi, H., Mohammed, D., Gonzalez, A., Paul, R., Wanigaratne, S., Gawad, T.,
Rawson, R., Al Marzooqi, A., & Al Ghaferi, H. (2017). National Rehabilitation Center programme
performance measures in the United Arab Emirates, 2013. Eastern Mediterranean Health Journal, 23(3), 182-
188.
233. Rawson, R.A., Mooney, L.J., Glasner, S., & Gonzales, R. (2017). Innovations in behavioral treatments for
substance use disorders. International Addiction Review, 1(1), 14-21.
234. Cousins, S.J., Crèvecoeur-MacPhail, D., Kim, T., & Rawson, R.A. (2018). The Los Angeles County hub-and-
provider network for promoting the sustained use of extended-release naltrexone (XR-NTX) in Los Angeles
County (2010-2015). Journal of Substance Abuse Treatment, 85, 78-83. doi: 10.1016/j.jsat.2017.02.011.
235. Garneau, H.C., Venegas, A., Rawson, R.A., Ray, L.A., & Glasner, S. (2018). Barriers to initiation of extended
release naltrexone among HIV-infected adults with alcohol use disorders. Journal of Substance Abuse
Treatment, 85, 34-37.
236. Crèvecoeur-MacPhail, D., Cousins, S.J., Denering, L., Kim, T., & Rawson, R.A. (2018). Effectiveness of
extended release naltrexone to reduce alcohol cravings and use behaviors during treatment and at follow-up.
Journal of Substance Abuse Treatment, 85, 105-108.
237. Krebs, E., Enns, B., Evans, E., Urada, D., Anglin, M.D., Rawson, R.A., Hser, Y.-I., & Nosyk, B. (2018). Cost-
effectiveness of publicly funded treatment for opioid use disorders in California. Annals of Internal Medicine,
168(1), 10-19. doi: 10.7326/M17-0611
238. Wolitzky-Taylor, K., Drazdowski, T.K., Niles, A., Roy-Byrne, P., Ries, R., Rawson, R., & Craske, M.G.
(2018). Change in anxiety sensitivity and substance use coping motives as putative mediators of treatment
efficacy among substance users. Behaviour Research and Therapy, 107, 34-41.
239. Wolitzky-Taylor, K., Niles, A.N., Ries, R., Krull, J.L., Rawson, R., Roy-Byrne, P., & Craske, M. (2018). Who
needs more than standard care? Treatment moderators in a randomized clinical trial comparing addiction
treatment alone to addiction treatment plus anxiety disorder treatment for comorbid anxiety and substance use
disorders. Behaviour Research and Therapy, 107, 1-9.
240. Wolitzky-Taylor, K., Krull, J., Rawson, R., Roy-Byrne, P., Ries, R., & Craske, M.G. (2018). Randomized
clinical trial evaluating the preliminary effectiveness of an integrated anxiety disorder treatment in substance
use disorder specialty clinics. Journal of Consulting and Clinical Psychology, 86(1), 81-88.
241. .El Magd, S.A., Khalil, M.A., Gohar, S.M., Enaba, D., Abdelgawad, T.M.S., Hasan, N.M., Miotto, K., &
Rawson, R.A. (2018). Tramadol misuse and dependence in Egypt and the UAE: User characteristics and drug-
use patterns. International Addiction Review, 2, 6-13.
242. Rawson, R.A., Cousins, S.C., McCann, M. J., Pearce, R., Van Donsel, A. (2019) Assessment of medication
for opioid use disorder as delivered within the Vermont hub and spoke system. Journal of Substance Abuse
Treatment. 97, 84-90.
243. Wolitzky-Taylor, K., Rawson, R., Ries, R., Roy-Byrne, P. & Craske, M.G. (in press). Adaptation of
Coordinated Anxiety Learning and Management (CALM) for comorbid anxiety and substance use disorders:
Delivery of evidence-based treatment for anxiety in addictions treatment centers. Implementation Science
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