ANALISIS JURNAL

KEPERAWATAN GAWAT DARURAT 2

Untuk memenuhi tugas mata kuliah keperawatan gawat darurat Program Studi Keperawatan

Disusun Oleh :

Nama : Fathurozak
Nim : A11701546
Kelas : S1 Keperawatan 3A

PROGRAM STUDI S1 KEPERAWATAN

SEKOLAH TINGGI ILMU KESEHATAN MUHAMMADIYAH
GOMBONG
2019
 Clinical and laboratory profile of diabetic ketoacidosis in elderly with type 2 diabetes
mellitus

No Author Tahun Sampel Metode Hasil Kesimpulan

1 B. Anupama, P. 2019 A total of 100 type 2 Most of them DKA is more
Chandrasekhara, diabetes mellitus had prolonged common in
M. S. (T2DM) patients, diabetes with T2DM than
Krishnamurthy, ≥60 years, mean duration anticipated. The
Mohsin Aslam admitted in a rural of 7.3 ± 4.6 most common
tertiary medical years. 24 precipitating
center were included patients factor is
in this study. were newly infection
detected followed by
diabetes noncompliance
mellitus. even in elderly.
Systemic Majority had
infections seen poor glycemic
in 67 patients control.
(respiratory – All elderly
32.8%, diabetic patients
sepsis – with high serum
28.4%, acute glucose level
gastroenteritis must be
– 22.4%, and investigated for
urinary tract ketosis as the
infections– symptoms of
16.4%), were DKA are
the main minimal and
precipitating morbidity and
factors, mortality are
followed by high in these
noncompliance patients.
to drugs (34).
Osmotic
symptoms
were reported
by most (62)
followed by
pain abdomen
(56).
Dehydration
was seen in 72
patients,
whereas
altered
sensorium in
48. Blood
glucose at
presentation
(493.12 ±
72.38 mg/dl)
 and HbA1c
levels (9.63 ±
0.94%)
were found to
be elevated
with lowered
arterial pH
(7.14 ± 0.07)
and
bicarbonate
(13.7 ± 4.2
mEq/L).
22 had severe
acidosis and
10 had mild
acidosis.
There was no
mortality in the
present series.

Daftar pustaka
Anupama. B,Chandrasekhara. Krishnamurthy. S. M, Aslam Mohsin. (2019). Clinical and
laboratory profile of diabetic ketoacidosis in elderly with type 2 diabetes mellitus. Downloaded
free from http://www.bldeujournalhs.in on Monday, April 15, 2019, IP: 36.80.220.151]
 Dynamic regulation of plasma matrix metalloproteinases in human diabetic ketoacidosis

No Author Tahun Sampel Metode Hasil Kesimpulan

2. Martin Woo, Eric K. 2015 Plasma was DKA was associated MMPs are
Patterson, Gediminas obtained from with altered plasma dynamically
Cepinskas, Cheril children with type levels of regulated during
Clarson, Tatsushi 1 diabetes, either in MMP-2 (P < DKA.
Omatsu and Douglas DKA (n = 16) or 0.001), MMP-8 (P Plasma MMP-8 and
D. Fraser insulin controlled < 0.001), MMP-9 MMP-9
(CON; (P < 0.05), concentrations
n = 16). Antibody and TIMP-4 (P < correlate with DKA
microarray and 0.001), as severity and are
gelatin zymography compared with known to degrade
were CON. Elevated brain microvascular
used to quantify MMP-8 and MMP-9 endothelial
plasma MMPs and were both cell tight junctions.
their endogenous positively Thus, leukocyte-
tissue correlated with derived MMPs
inhibitors (TIMPs). DKA might
MMP severity (P < 0.05). contribute to DKA-
concentrations DKA was associated associated
were correlated with increased cerebrovascular
with leukocyte complications.
DKA severity (blood mRNA for MMP-8,
pH). Quantitative MMP-9, and TIMP-
PCR of leukocyte 4 (P < 0.005).
mRNA
was used to help
determine the
origin of plasma
MMPs.

Daftar Pustaka
Woo Martin , Patterson. K Eric , Cepinskas Gediminas , Clarson Cheril, Omatsu Tatsushi and D.
Fraser.D Douglas. (2015). Dynamic regulation of plasma matrix metalloproteinases in human
diabetic ketoacidosis. Received 4 May 2015; accepted 31 July 2015; advance online publication
18 November 2015. doi:10.1038/pr.2015.215
 Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis

No Author Tahun Sampel Metode Hasil Kesimpulan

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