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MV COmiD Wena Diver Protection Ante Mycotoxin Additive a an mA . r ie FE 4 et . rs cy INTRODUCTION Fungal contamination of agricultural products is often Mycotoxins cause toxic, teratogenic, _ mutagenic, unavoidable and of growing concer, because the carcinogenic effects, and/or depression of the immune frequency these products have toxic metabolites known as system. The fact that a great variety of mycotoxins affect, mycotoxins, Mycotoxin contamination can occur in the different organs in the urinary, digestive, nervous, repro- crop, during harvest, during storage, or even after the feed ductive and immune systems, makes difficult to establish a is manufactured. Mycotoxins are fairly stable compounds precise differential diagnosis. The most dangerous myco- that cause a wide variely of deleterious effects in poutry toxins in_poultry are aflatoxin, ochratoxin, T-2 toxin, and other animals, depending on age, and nutritional and fumonisin and deoxynivalenol (D0N).. health status at the time of exposure to contaminated feed. taace Anoroves : @B) feats rexteaoy: SPAR AFLATOXIN Effect of Afiatoxin and Mycoad on broiler chicks after 21 days of consuming the experimental diets COA m Sa bral a Sha 74a 1.458 2.968 5.0 kg MYCOAD 7352 1088 21.462 3.008 2.8 ppm Aflatoxin sae 737 | 1468 4616 2.8 ppm Afiatoxin+ 25kgMYCOaD 668b 701.47 3834 _8,¢ Values within each column with iterent letters are significantly different (P< 0.05) Poultry Science Vol. 89, Suppl. tp. 817 2010. OCHRATOXIN Effect of Ochratoxin and Mycoad on 28 day old brollers Step ediel Meee Ud a Pres — er ce a irr A cs Control 31058490 (Negalive 2.5 kg MYCORD 3uiza 498 Negative = 1.198 Negative 19+ 8+ 2.0 ppm Ochratoxin —2967h_— 4894+. Bie Base reer 2.0 ppm Ochr: a i ! ppm Ochratoxin 194 19+ eee 48 1230 +25kg MYCOAD ale+ Oe ‘ Bate 13448 Score in Nagata (), Moderate (1, sont (+), Severe (20). F rb" aes wn ccc wih alert ters ae signa erent 6.8) pny sce ot oma 70tn eI T-2 TOXIN Effect of T-2 toxin and Mycoad on broilers at different ages CD Bg Cd ray Contcol 538a 08 0.308 ppm T-2Toxin 463b 1.84b 0.20 788b 1.63b 0.20b 1 ppm T-2 Toxin ald ¥ zany mvcoao 528 0362 0.282 838a O22 0.402 ‘Vues within each coluran wi diferent loters ac significantly afferent (P< 0.08) Total incidence and severity of oral lesions 2 30 s 2 amr Control 5 20 2 15 mm 1-2 3 10 ummm 7-2+ MYCOAD Ss #0 5 Poultry Science Vol, 84, Supp. tp. 132.2005 Mild Moderate Severe FUMONISIN Effect of Fumonisin and Mycoad on broiler chicks after 21 days of consuming the experimental diets Co ee Treatment Per ed ror Cory O O Controt Tia 15a 1600 31ST 100 ppm Furnonisin 651c 1093¢ «1.68 = 3.908035. 100 ppm Furnonisin + 2.5kgMYCOMD 679b 1115b 64a 32a Sha ‘ybye aloes within each clam wit liforent ters are signiicaneterent P< 0.05) Poultry Science Vol. 91, Supp. 1p. 128.2012 CONCLUSIONS MYCOAD controlled in a statistically significant manner the toxic effects caused by aflatoxin, ochratoxin, T-2 toxin, and fumonisin on broiler performance, with a significant protection of target organs. No negative effects were seen on productive parameters of birds treated only with MYCOAD, showing results statistically similar to those of the controls. Uuss fui le heaton d Cron Meet ihe Pasig OR BArAGTS 7) Target Qrgan Protection Aflatoxin Uver YES No Ochratoxin Kidney YES No T2Toxin Oral lesion YES YES Fumonisin Heart / Lung / Liver YES YES Zearalenone Reproductive No YES DON Liver No YES | Se es In vivo dosage with TOP results 2.5 kg / MT 1kg/ MT" Commercial recommended dosage 25 kg/ MT 1kg/MT The CLAY component always from the same MINE YES Yes Approved in TEXAS YES No Approved by LAMIG for atleast TWO mycotoxins YES YES Approved by LAMIC in 5 species YES No Nutrient Absorption No No {In vitro efficacy test every 18 Mt or 100 MT YES YES ENDOTOXIN adsorption NO YES Tesperformeawith kg with 30,000 ppb ol Famonsie # Special Nutrients Inc. 4g ‘The mycotoxins specialist ‘www.mycotoxin.com et ——

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