Slide 1

GI Histology Review
Jennifer Dennis, PhD
jdennis@kcumb.edu

Slide 2 1. Identify these

1. Mucous acini -> Mucous secretory
structures, what do they
produce?
product
2. Identify these
2. Serous acini -> serous/watery
structures, what do they
produce?
secretory product
3. Mucoserous acini -> Mixed
secretory product
3. Identify these structures
(yellow circles), what do
they produce?

Slide 3 1. Identify this organ

1. Parotid salivary gland
2. Submandibular salivary gland
2. Identify this organ
Slide 4 Complete the duct pathway: Acinus -> Intercalated duct
Acinus
↓
(squamous-to-low cuboidal
_________ (________epithelium) epithelium) -> Striated duct
↓
_________ (________epithelium) (cuboidal-to-columnar epithelium)
↓
_________ (________epithelium) ->Interlobular duct
↓
_________ (________epithelium) (pseudostratified columnar) ->
↓
Main duct Lobar duct (stratified columnar) ->
Main duct

Slide 5 1. This is the upper third of the

1. Identify
this layer esophagus; therefore, the outer
tunic is the adventitia
2. Identify
this layer 2. Submucosa (glands are included in
the image)

Slide 6 1. Identify the region 1. Pyloric stomach

2. How do you know? Describe the hallmarks for this region.

2. Gastric pits & glands. Gastric pits

are wide & extend deeper into
mucosa (as compared to other
gastric regions). Straight glands
that branch; lined with mucous
producing cells, lack of parietal
cells.
Slide 7 1. This is the myenteric plexus of
1. Identify these
structures
Auerbach
1. Identify these
2. Muscularis/muscularis externa
structures

2. What tunic is this

structure located within?

Slide 8 1. Muscularis/muscularis externa

2. Identify
this layer 2. Mucosa
3. Gastroesophageal junction

1. Identify 3. What specific area

this layer of the GI tube is this?

Slide 9 1. Duodenum w/Brunner’s glands

2. Pyloric sphincter

1. Identify
this organ
(yellow)

2. Identify
this
structure
Slide 10 1. Identify this organ
2. What specific region is shown in the image? 1. Stomach
2. This is the cardiac region, as
Same tissue with
indicated by the tubular coiled
mucosa enlarged
glands shown in cross-section &
oblique section

Slide 11 1. Identify this organ

2. What specific region is 1. Small intestine
shown in the image?

2. Jejunum (elongated villi, but no

Brunner’s glands & no Peyer’s
patches)

Slide 12 Same organ as previous slide:

1. Identify the structure in the 1. Plica circulares
red bracket.
2. What are indicated by the
red arrows? 2. Villi
3. What lymphatic structure
would you find in the core of
#2?
3. lacteal
Slide 13 1. Identify ‘A’ vs ‘B’
2. Give the epithelium
found in each location
Slide 14 1. Identify this specific organ
2. Identify these
structures (blue circles)
Slide 15 1. Identify this organ
2. What specific region is shown in the image?
‘A’ ‘B’
1. A=large intestine; B=upper
rectum/rectum proper
2. A=simple columnar epithelium;
B=nonkeratinized stratified
squamous
1. SI, duodenum
2. Brunner’s glands
• Review/identify the regions of the
gastric pit/glands
3. Identify cell types in each region
1. Stomach
2. Fundus/body region
3. Pit (surface mucous cells), neck
(mucous neck cells, some parietal
cells), body (extensive parietal
cells, stem cells), lower body
(extensive chief cells,
enteroendocrine cells)
Slide 16 1. Identify this organ 1. Pancreas
2. How are the glands organized? What is the gland structure?

2. Branched tubuloacinar gland

Slide 17 1. Identify this organ (red bracket) 1. Large intestine

2. This is the serosa/adventitia layer:
ascending/descending
colon/rectum (adventitia),
cecum/transverse/sigmoid colon
(serosa)
2. Identify this layer for the length of the organ, indicate
changes, if any, depending on position.

Slide 18 1. Identify this organ - specific location?

2. How are the glands organized/what is the gland structure?
1. Stomach, fundus/body region
2. Simple tubular, branched glands,
EXCEPTION: cardiac glands – these
are simple tubular, coiled!
Slide 19 1. Identify the regions shown by the brackets
2. Give the cell types in each 1. A: pit; B: neck; C: body
A 2. Pit (surface mucous cells), neck
B
(mucous neck cells, some parietal
cells), body (extensive parietal
C cells, stem cells), lower body
(extensive chief cells,
3. What is this
structure
(yellow circle)?
enteroendocrine cells)
3. GALT

Slide 20 1. Identify this organ

2. Identify these cells
1. Large intestine
2. Goblet cells
(red arrow)

Slide 21 1. Identify this organ 2. Identify these structures (blue circles) 1. Ileum
2. Peyer’s patches
Slide 22 1. Identify this organ 2. Identify these structures (yellow circles) 1. Veriform appendix
2. Lymphoid follicles/nodules