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VIRUS (HSV)
Liza Qurrah Ayuniyyah
St. Wahida Adawiah Ansar
Tya Putri Permata
Opportunistic Infections
OPPORTUNISTIC INFECTIONS (OIS) ARE INFECTIONS THAT
OCCUR MORE OFTEN OR ARE MORE SEVERE IN PEOPLE WITH
WEAKENED IMMUNE SYSTEMS THAN IN PEOPLE WITH
HEALTHY IMMUNE SYSTEMS. PEOPLE WITH WEAKENED
IMMUNE SYSTEMS INCLUDE PEOPLE LIVING WITH HIV
opportunistic infections (OIs), including a variety of viral, fungal,
bacterial, and protozoal diseases. Herpes simplex virus (HSV)
infections in persons infected with HIV usually occur as a result of
the reactivation of virus that has been present in the body long
before infection with HIV. HSV causes skin and mucous
membrane infections in persons with HIV infection, just as it does
in individuals with normal immune systems. In persons with HIV,
however, these reactivated infections may be severe and
protracted. Longstanding severe HSV lesions, in fact, can be one
of the first symptoms of AIDS. Nonetheless, even in AIDS patients,
HSV lesions typically remain localized and do not spread
throughout the body
HERPES SIMPLEX
VIRUS
Herpes simplex viruses (HSV) commonly
known as herpes. herpes simplex is an
infection of the skin with the hsv. HSV
remains latent in nerve root ganglia of
infected persons and is trought to reactive
several time yearly. hsv is transmitted by
closed personal contact and infection occur via
inoculation of virus into susceptible mucosal
surfaces (eg. oropharyx, cervix, conjunctiva)
or through small cracks in the skin.
There are 2 types of herpes
virus :
HERPES TYPE 1 (HSV-1) WHICH IS TRANSMITTED
THROUGH ORALSECRETION OR SORES ON THE
SKIN.
HERPES TYPE 2 (HSV-2) TRANSMITTED DURING
SEXUAL CONTACT WITH SOMEONE WHO HAS A
GENITAL HSV-2 INFECTION.
Epidemiology
Worldwide rates of either HSV-1 or HSV-2 are
between 60 and 95% in adults.
Prevalence of HSV-2 in those between the ages of
15 and 50 is about 535 million as of 2003 or 16% of
the population, with highest rates in in sub-Sahara
Africa and lowest in western Europe, and with
greater rates among women and those in the
developing world
In 2012, an estimated 3.7 billion people under the age of 50,
or 67% of the population, had HSV-1 infection. Estimated
prevalence of the infection was highest in Africa (87%) and
lowest in the Americas (40-50%). With respect to genital
HSV-1 infection, 140 million people aged 15-49-years were
estimated to have genital HSV-1 infection worldwide in 2012,
but prevalence varied substantially by region. Most genital
HSV-1 infections are estimated to occur in the Americas,
Europe and Western Pacific, where HSV-1 continues to be
acquired well into adulthood.
CLINICAL MANIFESTATION
MANY PEOPLE INFECTED WITH
HSV-2 DISPLAY NO PHYSICAL NEONATAL HERPES SIMPLEX IS
SYMPTOMS-INDIVIDUALS WITH A HSV INFECTION IN AN GINGIVOSTOMATITIS AND
NO SYMPTOMS ARE DESCRIBED INFANT. IT IS A RARE BUT OROLABIAL HSV INFECTION.
AS ASYMPTOMATIC OR AS SERIOUS CONDITION, USUALLY GINGIVOSTOMATITIS IS A
FOLLOWING A PRIMARY INFECTION, SUBCLINICAL HERPES. PEOPLE CAUSED BY VERTICAL SYMPTOMATIC PRIMARY HSV-1
THE VIRUS ENTERS AT THE SITE OF WITH IMMATURE OR TRANSMISSION OF ( HSV-1 OR 2) INFECTION, USUALLY
PRIMARY INFECTION, MIGRATES TO FROM MOTHER TO NEWBORN. OCCURRING IN CHILDREN, AND
SUPPRESSED IMMUNE SYSTEMS,
CELL BODY OF THE NEURON, AND DURING IMMUNODEFICIENCY CHARACTERIZED BY LESIONS IN
SUCH AS NEWBORNS,
BECOMES LATENT IN THE GANGLION. ,HERPES SIMPLEX CAN CAUSE AND AROUND THE ORAL CAVITY.
TRANSPLANT RECIPIENTS, OR
AS A RESULT OF PRIMARY UNUSUAL LESIONS IN THE SKIN CHILDREN ARE OFTEN UNABLE
PEOPLE WITH AIDS, ARE PRONE
INFECTION; THE BODY PRODUCES .ONE OF THE MOST STRIKING IS TO SWALLOW BECAUSE OF THE
TO SEVERE COMPLICATIONS
ANTIBODIES TO PARTICULAR TYPE OF THE APPEARANCE OF CLEAN ASSOCIATED PAIN AND MAY
FROM HSV INFECTIONS
HSV INVOLVED, PREVENTING A LINEAR EROSIONS IN SKIN BECOME DEHYDRATED.
SUBSEQUENT INFECTION OF THAT CREASES
TYPE AT A DIFFERENT SITE
TREATMENT