DRUG STUDY

GENERIC NAME: MECHANISM OF ACTION: SIDE EFFECTS: NURSING RESPONSIBILITIES:

CEFUROXIME Second generation cephalosporin
that inhibits cell-wall synthesis,
promoting osmotic instability; usually
BRAND NAME: bactericidal.
ZOLTAX
INDICATION:
CLASSIFICATION: Pharyngitis, Tonsillitis, infections of
ANTIBIOTIC the urinary and lower respiratory
tracts, and skin structure infections
caused by streptococcus pneumonia
DOSAGE/FREQUENCY: and S. pyogenes, Haemophillus
1 tab 500mg BID influenza, Staphylococcus aureus,
Escherechia Coli
ROUTE:
PO
CONTRAINDICATION:
Contraindicated in patients
hypersensitive to drugs.
Use cautiously in patients
hypersensitive to penicillin because
of possibility of cross sensitivity with
other beta-lactam antibiotics
 Determine history of
Body as a whole: hypersensitivity reactions to
Thrombophlebitis (IV Site); pain, cephalosphorins, penicillins
burning, cellulitis (IM Site); and history of allergies
superinfections, positive Coomb’s particularly to drugs before
Test. therapy is initiated.
GI:  Report onset of loose stools
Diarrhea, antibiotic-associated colitis.
Skin:  Absorption of cefuroxime is
Rash, pruritus, urticartia. enhanced by food.
Urogenital:  Notify prescriber about
Increased serum cretonne and BUN, rashes or superinfections.
decreased creatinine clearance
ADVERSE EFFECTS:
Large doses can cause cerebral
irritation and convulsions; nausea,
vomiting, diarrhea, GI disturbances;
erythema multiforme, Stevens-
Johnson syndrome, epidermal
necrolysis.

Potentially Fatal: Anaphylaxis,

nephrotoxicity, pseudomembranous
colitis.
 DRUG STUDY

GENERIC NAME: MECHANISM OF ACTION: SIDE EFFECTS: NURSING RESPONSIBILITIES:

MEFENAMIC ACID
BRAND NAME:
DOLFENAL
CLASSIFICATION:
NSAID(Nonsteroidal Anti-
inflammatory Compounds)
ANTIPYRETIC; CENTRAL NERVOUS
SYSTEM AGENT; ANALGESIC
The analgesic effects of NSAIDs may
result from interference with the
prostaglandins involved in pain.
Prostaglandin appear to sensitize
pain receptors to mechanical
INDICATION:
Mild to moderate pain, inflammation, occurs occasionally.
stiffness, swelling or tenderness
caused by surgical procedure
(Lipincott W, 2009)
 Assess patient’s level of pain
CNS: and inflammation before
Drowsiness, insomnia, diziiness, therapy.
nervousness, confusion, headache
 Monitor ophthalmic and
GI: auditory function before and
Abdominal pain, dyspepsia, epigastric periodically during therapy.
distress, nausea, nephrotoxicity
 Monitor RBC, platelet count,
Skin: and hepatic and renal
Rash, facial edema, urticartia. function studies periodically.

CONTRAINDICATION: Whole Body:  Be alert for adverse reactions

DOSAGE/FREQUENCY: Contraindicated in patients Perspiration and drug interactions.
1 tab 500mg PRN for pain hypersensitive to drugs.
Use cautiously in patients CV: Palpitation
ROUTE: hypersensitive to penicillin because
PO of possibility of cross sensitivity with Respiratory: Dyspnea, acute
other beta-lactam antibiotics exacerbation of asthma,
bronchoconstriction

ADVERSE EFFECTS:
Mefenamic acid can cause a severe
allergic reaction. Symptoms may
include: trouble breathing.