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DRUG NAME MECHANISM OF INDICATION / ADVERSE EFFECT NURSING RESPONSIBILITIES

ACTION CONTRAINDICATION

GENERIC: Paracetamol may INDICATIONs: Hematologic: BEFORE:


Paracetamol cause analgesia by Temporary relief of pain and hemolyticanemia, Dx:
inhibiting CNS discomfort from headache, neutropenia, a. Asses patient’s drug history and calculate
BRAND: prostaglandin fever, cold, flu, minor muscular leukopenia, total daily dosage accordingly:
Tylenol synthesis. The aches, overexertion, menstrual pancytopenia b. Assess patient’s temperature before
mechanism of cramps, toothache, minor therapy and regularly thereafter.
CLASS: morphine is believed arthritic pain. Hepatic: c. Check for allergies
Analgesics ( Non- to involve decreased liver damage, Tx:
opioid) permeability of the CONTRAINDICATION: d. Monitor CBC, liver and renal functions.
Antipyretics cell membrane to Paracetamol is Metabolic: EDx:
sodium, which results contraindicated for use in hypoglycaemia e. Educate SO on drug therapy to promote
THERAPEUTIC in diminished patients with known compliance.
Pain reliever and transmission of pain hypersensitivity or idiosyncratic Skin:
fever reducer impulses therefore reaction to paracetamol (or rash, urticaria DURING:
analgesia. any of the other ingredients in Dx:
PHARMACOLOGIC: the product); a. Monitor for adverse effects like respiratory
Source: dysfunctions
DOSAGE: https://onlinelibrary.w DRUG TO DRUG INTERACTION: b. Check for drug or herbal interactions
20/mg/kg/dose iley.com/doi/10.1111 Barbiturates, carbamapezine, Tx:
/j.1460- hydantoins, isoniazid, rifampin, c. Do not give children more than 5 doses in
ROUTE: 9592.2008.02764.x sulfinpyrazone: May reduce 24 h unless prescribed by physician.
IV therapeutic effect and EDx:
enhance hepatotoxic effects d. Report diarrhea, nausea, dyspepsia,
of acetaminophen with high insomnia, drowsiness, dizziness, or persistent
doses or long-term use of headache to physician.
these drugs. Avoid use
together. AFTER:
Warfarin: May increase Dx:
hypoprothrombin-emic effect a. Assess knowledge/teach SO appropriate
with long-term use of high use ,interventions to reduce side effects,
doses. and adverse symptoms to report
Zidovudine: May increase risk b. Monitor for effectiveness as exhibited by a
of bone marrow suppression decrease in symptoms
because of impaired c. Monitor for side effects.
zidovudine metabolism. Tx:
d. Provide safety measures to prevent injuries.
DRUG TO FOOD INTERACTION: e. Provide comfort measures like telling things
_________________ to avoid to help patient tolerate drug
effects.
f. Administer drug once a day in the evening
to achieve optimal therapeutic effects.
EDx:
g. Monitor patient for 2-4 weeks to ascertain
onset of full therapeutic effect.
h. Teach client warning signs that needs
immediate attention of the physician.

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