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Paracetamol is indicated for temporary relief of pain and fever. Its mechanism of action involves inhibiting central nervous system prostaglandin synthesis. Adverse effects include hematologic, hepatic, metabolic and skin reactions. Nursing responsibilities before administration include assessing drug history, allergies, and temperature. Nurses should monitor for adverse effects and drug interactions during treatment. After treatment, nurses educate patients on appropriate use and side effects to report.
Paracetamol is indicated for temporary relief of pain and fever. Its mechanism of action involves inhibiting central nervous system prostaglandin synthesis. Adverse effects include hematologic, hepatic, metabolic and skin reactions. Nursing responsibilities before administration include assessing drug history, allergies, and temperature. Nurses should monitor for adverse effects and drug interactions during treatment. After treatment, nurses educate patients on appropriate use and side effects to report.
Paracetamol is indicated for temporary relief of pain and fever. Its mechanism of action involves inhibiting central nervous system prostaglandin synthesis. Adverse effects include hematologic, hepatic, metabolic and skin reactions. Nursing responsibilities before administration include assessing drug history, allergies, and temperature. Nurses should monitor for adverse effects and drug interactions during treatment. After treatment, nurses educate patients on appropriate use and side effects to report.
DRUG NAME MECHANISM OF INDICATION / ADVERSE EFFECT NURSING RESPONSIBILITIES
ACTION CONTRAINDICATION
GENERIC: Paracetamol may INDICATIONs: Hematologic: BEFORE:
Paracetamol cause analgesia by Temporary relief of pain and hemolyticanemia, Dx: inhibiting CNS discomfort from headache, neutropenia, a. Asses patient’s drug history and calculate BRAND: prostaglandin fever, cold, flu, minor muscular leukopenia, total daily dosage accordingly: Tylenol synthesis. The aches, overexertion, menstrual pancytopenia b. Assess patient’s temperature before mechanism of cramps, toothache, minor therapy and regularly thereafter. CLASS: morphine is believed arthritic pain. Hepatic: c. Check for allergies Analgesics ( Non- to involve decreased liver damage, Tx: opioid) permeability of the CONTRAINDICATION: d. Monitor CBC, liver and renal functions. Antipyretics cell membrane to Paracetamol is Metabolic: EDx: sodium, which results contraindicated for use in hypoglycaemia e. Educate SO on drug therapy to promote THERAPEUTIC in diminished patients with known compliance. Pain reliever and transmission of pain hypersensitivity or idiosyncratic Skin: fever reducer impulses therefore reaction to paracetamol (or rash, urticaria DURING: analgesia. any of the other ingredients in Dx: PHARMACOLOGIC: the product); a. Monitor for adverse effects like respiratory Source: dysfunctions DOSAGE: https://onlinelibrary.w DRUG TO DRUG INTERACTION: b. Check for drug or herbal interactions 20/mg/kg/dose iley.com/doi/10.1111 Barbiturates, carbamapezine, Tx: /j.1460- hydantoins, isoniazid, rifampin, c. Do not give children more than 5 doses in ROUTE: 9592.2008.02764.x sulfinpyrazone: May reduce 24 h unless prescribed by physician. IV therapeutic effect and EDx: enhance hepatotoxic effects d. Report diarrhea, nausea, dyspepsia, of acetaminophen with high insomnia, drowsiness, dizziness, or persistent doses or long-term use of headache to physician. these drugs. Avoid use together. AFTER: Warfarin: May increase Dx: hypoprothrombin-emic effect a. Assess knowledge/teach SO appropriate with long-term use of high use ,interventions to reduce side effects, doses. and adverse symptoms to report Zidovudine: May increase risk b. Monitor for effectiveness as exhibited by a of bone marrow suppression decrease in symptoms because of impaired c. Monitor for side effects. zidovudine metabolism. Tx: d. Provide safety measures to prevent injuries. DRUG TO FOOD INTERACTION: e. Provide comfort measures like telling things _________________ to avoid to help patient tolerate drug effects. f. Administer drug once a day in the evening to achieve optimal therapeutic effects. EDx: g. Monitor patient for 2-4 weeks to ascertain onset of full therapeutic effect. h. Teach client warning signs that needs immediate attention of the physician.