1. Which site represents the most oxygenated blood in the fetus?

A. The fetal aorta

B. The umbilical vein
C. The fetal carotid artery
D. Both of all

2. In the fetus, essential amino acids are used for:

A. Oxidation
B. Growth
C. Both A and B

3. Which measurement represents the amount of a nutrient delivered to the fetus?

A. Umbilical blood flow
B. Umbilical uptake
C. Fetal arterial concentration
D. All of them

4. Are all 20 amino acids in the genetic code delivered to the fetal circulation from the
mother?
A. Yes
B. No

5. The metabolic rate of the placenta is:

A. Higher than that of the fetus
B. Lower than that of the fetus
C. The same as that of the fetus

6. Which is the last component of the lateral ventricle to undergo a modification of its
shape?
A. Frontal horns
B. Occipital horns
C. Atria
D. Body

7. The term mild ventriculomegaly is commonly used to indicate cases with an atrial
width of:
A. 10–12 mm
B. 10–15 mm
C. 10–18 mm
D. 15–20 mm

8. The etiology of aqueductal stenosis includes:

A. Infections
B. True malformations
C. Congenital tumors
 D. All of the above
9. Communicating hydrocephalus:
A. Results from failure of reabsorption of cerebrospinal fluid
B. Is characterized in the early stages by enlarged subarachnoid channels
overlying the cerebral hemispheres only
C. Has a multifactorial etiology with a recurrence risk of 1–2%
D. Is never associated with a choroid plexus papilloma

10. Which method is most reliable for the prenatal diagnosis of hydrocephalus?
A. Head ultrasound measurements
B. Measurement of the lateral ventricular ratio
C. Qualitative evaluation of the intracranial structures
D. Measurements of the internal diameter of the atria of the lateral ventricle

1.Which of the following is not a heritable thrombophilia ?

a. Factor V Leiden mutation
b. Homocysteine deficiency
c. Antithrombin III deficiency
d. G20210A prothrombin gene mutation
e. Protein S deficiency

2.The following statement is not true regarding heritable thrombophilias and pregnancy :
a. Heritable thrombophilias are associated with RPL
b. Heritable thrombophilias are associated with fetal death
c. Heritable thrombophilias are associated with venous thromboembolism
d. Most women with heritable thrombophilias suffer pregnancy loss

3.The following statement is not true regarding the use of leukocyte immunization and IVIG
to treat RPL :
a. These are two therapies aimed at treating alloimmune pregnancy loss
b. These therapies are expensive and have meaningful side-effects
c. These therapies have been proven to improve outcome in women with RPL in
randomized clinical trials
d. These therapies are not recommended for the treatment of RPL

4.Which of the following is incorrect ?

a. Ferritin levels should be checked when the patient is not taking iron
b. Parenteral iron can cause anaphylaxis
c. The mean corpuscular volume (MeV) of a patient with an iron deficiency can be in the
normocytic range
d. Useful iron studies include measurements of ferritin,total iron-binding capacity (TIBC),
and transferrin

5.Which of the following does not cause megaloblasticanemia ?

a. A deficiency in vitamin B12
b. A deficiency in folic acide
c. Lead poisoning
d. Malabsorbtion

6.Which of the following statements is correct ?

a. Gestational thrombocytopenia (GT) and immune thrombocytopenia purpura (lTP) can
easily be differentiated by checking anti platelet antibodies
b. A platelet count of 120000/1 can be attributed to ITP
c. Regional anesthesia can be administered safely to patients with a platelet count of
25000/1
d. A safe platelet count for vaginal delivery is around 50000/1

7.The first-line treatment of ITP is :

a. Administration of corticosteroids
b. Administration of intravenous immunoglobulin (IVIG)
c. A splenectomy
d. Administration of azathioprine

8.Which of the following statements about alloimmune thrombocytopenia purpura (AITP) is

incorrect ?
a. The first newborn may be affected with thrombocytopenia
b. In an infant, thrombocytopenia caused by ITP has a worse outcome than
thrombocytopenia caused by ITP
c. Corticosteroids have a consistent effect on the fetal platelet count
d. There is no reliable screening method available for AITP

9.Which of the following treatments is incorrectly matched to the disorder ?

a. Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome - high-dose
dexamethasone
b. Thrombotic thrombocytopenic purpura (TTP) -plasma pheresis
c. Hemolytic uremic syndrome - antibiotics
d. AITP - IVIG

10.Which of the following statements about von Willebrand's disease (vWD) is incorrect ?
a. von Willebrand's factor (vWF) binds platelets to damaged endothelium
b. vWD can only be treated with vasopressin or cryoprecipitate
c. Vasopressin increases the amount of vWF released by the endothelium
d. Type 2B and type 3 vWD patients should not receive vasopressin
 11.Which of the following statements is correct ?
a. Obstetrical antiphospholipid antibodies will cause thrombosis and cause the activated
partial thromboplastin time (PTI) to be elevated
b. The presence of antiphospholipid antibodies always requires treatment for prevention of
pregnancy loss
c. The current treatment for obstetrical anti phospholipid antibodies uses prednisone to
decrease the amount of circulating antibodies
d. Antiphospholipid antibodies can cause a false negative rapid plasma reagin (RPR)

12.Which of the following statements about Factor V Leiden is incorrect ?

a. The mutation results in Factor V being resistant to neutralization by the protein C/protein
S complex
b. Factor V Leiden is present in approximately 1 out of11 to 1 out of 20 pregnancies in
Northern Europe
c. Factor V Leiden heterozygosity is associated with a shortened lifespan
d. Factor V Leiden homozygosity is considered to be a "greater" thrombophilia

13.Which of the following associations is incorrect ?

a. Pregnancy - decreased protein C
b. Heparin - decreased antithrombin activity
c. Warfarin - decreased protein S antigen
d. Warfarin - increased antithrombin activity

14.Which of the following is not considered to be a "lesser" thrombophilia ?

a. Antithrombin deficiency
b. Protein C deficiency
c. Protein S deficiency
d. Factor V Leiden heterozygosity

15.During pregnancy, systemic lupus erythematosus (SLE) may be confused with :

a. Pregnancy-induced hypertension
b. Myasthenia gravis
c. Hypothyroidism
d. Epilepsy
e. All of the above

16.SLE affects pregnancy by :

a. Increasing late pregnancy fetal losses
b. Increasing neonatal heart block
c. Increasing the incidence of late abortions
d. All of the above
e. None of the above

17.What is the effect of pregnancy on SLE ?

 a. Does not affect the long-term prognosis
b. May cause "flare ups"
c. May have no effect
d. All of the above
e. None of the above

18.The incidence of SLE may be affected by :

a. Weight
b. Metabolic state
c. Race
d. Diet
e. History of multiple infections

19.Renal impairment associated with poor prognosis in pregnant women with lupus nephritis is determined
by :
a. Creatinine clearance < 60 mUmin
b. Proteinuria >3 gl24 h
c. Serum creatinine >1.5 mgldL
d. All of the above
e. None of the above

20.From the following antibodies, which one is most commonly present in women with SLE
?
a. Antinuclear antibodies (ANA)
b. Anti-ds DNA
c. Anti-Sm
d. Anti-Ro (SS-A)

21.For patients with lupus nephritis, what is the incidence of permanent renal failure
secondary to pregnancy ?
a. 40%
b. 7%
c. 80%
d. 2%
e. 30%

22.Which of the following is a risk factor for developing preeclampsia in a woman with SLE
?
a. Lupus nephritis
b. Antiphospholipid antibody syndrome
c. Chronic hypertension
d. All of the above

23.The risk of preterm labor in women with SLE is :

a. Approximately 20-50%
b. Frequently associated with premature rupture of the membranes (PROM)
c. Not different from that of the general population
d. A and B

24.Which of the following is not a clinical criterion for antiphospholipid syndrome (APS) ?
a. Thrombosis
b. Hypertension
c. Recurrent spontaneous abortion
d. Fetal death

25. The two anti phospholipid antibodies that are best characterized include :
a. Lupus anticoagulant and anticardiolipin antibodies
b. Lupus anticoagulant and antinuclear antibodies
c. Antinuclear and anticardiolipin antibodies
d. Antiphosphatidylinositol and antiethanolamine antibodies