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STRUCTURE DESCRIPTION

(a) Pancreatic It is also called as Islet of Langerhans. It has either


islet round or oval shaped that contains islands of small
cells which helps in regulate blood sugar level by
producing hormones. There are five different types
produced by it, first and foremost, it is alpha cell that
produces glucagon, it occupies approximately 15%
of pancreatic islet. Alpha cell will produce hormone
glucagon when our blood sugar level is low .
Glucagon converts glycogen into glucose in order
to raise the blood sugar level. Next, in the purpose
of reducing our blood sugar level, beta cell
produces insulin and amylin. Hormone insulin
synthesizes the glycogen, protein and fatty acids
followed by facilitating the uptake of glucose into
cells and stimulates the liver cell to activate
glucokinase (an enzyme that converts glucose into
glucose-6 phosphate and acts as glucose sensor).
Beta cells occupies the most in the pancreatic islet
which is approximate 75% and mostly located in the
centre. However, the amylin aids to slow down the
speed of gastric emptying and prevents spikes in
blood sugar level. Delta cells also locates in the
pancreatic islet that play a role as secreting
somatostatin to inhibit the release of alpha and
beta cells. Other than that, gamma cell produces
pancreatic polypeptide that stimulates gastric chief
cells, supresses the production of bile and the
secretion of bicarbonate. Lastly, epsilon cells
produces ghrelin that makes us feel hungry. ("The
Pancreas | Boundless Anatomy and Physiology", n.d.)
(b) Interlobular It is dense and collagenous tissue. Interlobular
connective connective ducts associates the interlobular duct to
tissue support blood and lymph vessels, nerve ,ganglia
and pancreatic duct.
( c) Interlobular It is also called as intercalated duct. It has the lining
duct of cuboidal epithelial cells that secrete bicarbonate
ions into the secretory products. This duct is
extended to acinar lumen which stains centroacinar
cells. It is also contains a small amount of
connective tissues surrounds them which may lead
to a larger interlobular duct that is prominent
connective tissue septa. When the ducts are lined
with a low columnar epithelium , it may contain
goblet cells which plays vital roles in mucosal
protection.
(d) Acinar cell Acinar comes from the Latin word acinus which
means berry .Indeed, it has a likely berry-shaped
and located in the exocrine cells of pancreas. It
synthesizes protein for exporting in a proactive
way .Hence, it is reflected in their bizonal staining
properties. Homogenzone which is the hemotoxylin
commonly stains intensely the basal region of these
secretory cells due to the presence of regimented
endoplasmic reticulum which contains ribosomes
that synthesize the protein . Zymogen zone which
means that the presence of large amounts of
zymogen granules containing high concentrations
of protein is because of the intense eosin staining in
the apical region of the secretory cells. After we
took a meal ,there is least abundant of these
granules in the acinar cell.
( e) Pacinian The It has oval-shaped and has a lining of
corpuscle connective tissues. In its centre, there is an inner
core that have a myelinated nerve ending. A
resemble of layers of an onion is surrounded the
core of layers of flattened cells.It is one of the major
types of mechanoreceptor which has high density
occurring in area that are for the sensitivity to touch.
It is found within joint capsule carry information to
the central nervous system regarding the
differences of joint pressure, they triggers action
potential to happen in the free nerve ending
embedded within them. ("What Is the Function of the
Pacinian Corpuscles?", n.d.)
(f) Blood vessel As we know, blood vessels play a role of supplying
nutrients and oxygen to all types of cells. However, it
is also found that it helps in pancreas formation from
early specification of the initial pancreatic bud
which means maturation or growth of the
pancreatic bud. It is essential for the endocrine
specification at the onset of pancreatic
budding .After a few days, blood vessels inhibit
pancreatic branching and exocrine differentiation.

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