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Carpal tunnel syndrome is a painful, progressive condition that occurs when the
median nerve in the wrist is compressed.
Also known as median nerve entrapment or median nerve compression, it may happen
when a nerve swells, the tendons become inflamed, or something causes swelling in
the carpal tunnel.
Symptoms include tingling, burning, or itching and numbness in the palm of the hand
and the fingers, especially the thumb and index finger.
The National Institute of Neurological Disorders and Stroke (NINDS), describe carpal
tunnel syndrome (CTS) as the "most common and widely known of the entrapment
neuropathies in which the body's peripheral nerves are compressed or traumatized."
CTS affects between 3 percent and 6 percent of adults in the United States. It
normally develops between the ages of 45 and 64 years, and the prevalence increases
with age. It can appear in one or both wrists. It is more common in women than in
men.
Without treatment, CTS can have a negative impact on a person's quality of life.
Eventually, the median nerve can become severely damaged, and there may be
permanent numbness in the fingers and permanent weakness in the muscles that are
innervated by the median nerve.
It is often linked to computer use, but reports date back to the 1800s. It was familiar to
orthopedic surgeons since before the widespread use of computers.
The first symptoms often appear during the night, or on waking up in the morning.
Patients may feel the need to "shake out" their hands when they wake up. The
discomfort may wake them repeatedly during the night.
pain
numbness
tingling
These symptoms occur in the thumb and the two fingers next to it, as well as half of
the ring finger. They may extend to the rest of the hand and into the forearm.
As the condition progresses, symptoms may persist during the day. The person may
lose grip strength and find it harder to form a fist or grasp small objects. Opening a
bottle of soda, doing up buttons, or typing on a keyboard can become a challenge.
If left untreated, the muscles at the base of the thumb may wither away, and the
person may no longer be able to tell hot from cold with the thumb and finger.
Symptoms tend to emerge or get worse after using the affected hand. The sensation of
tingling, burning, and pain may worsen if the arm or hand has been in the same
position for a long time.
Treatment
Treatment aims to relieve symptoms and slow the progression of CTS by reducing
pressure on the median nerve.
People with mild symptoms may find their condition improves without treatment
within a few months, especially if they are aged 30 years or under or if CTS occurs
during pregnancy.
Self-help tips
Resting the hand and wrist: The more rest the hand and wrist get, the greater
the chance of relieving the symptoms.
Cold compress: Placing an ice pack on the wrist may help when the problem
flares up, but ice should not be applied ice directly onto the skin.
Controlling the triggers: If CTS stems from repetitive hand movements, the
person should take breaks so the hand and wrist have time to rest and recover.
Occupational therapy: A therapist can teach a person how to repetitive tasks
differently.
Wrist splints: These keep the wrist in the same position and prevent it from
bending. They can be worn during sleep, but also during the day if they do not
interfere with daily activities. Wrist splints are available over the counter at
pharmacies. A doctor or pharmacist can advise about the best one to choose.
Most patients with mild symptoms who follow these strategies will notice an
improvement within 4 weeks.
Medications
Other treatments that may help include exercises and botox injections.
Surgery
In severe cases, where treatments have not been effective, and symptoms have lasted
at least 6 months, surgery may be appropriate.
Surgery involves cutting the carpal ligament, which is the roof of the carpal tunnel, to
reduce pressure on the median nerve.
The Cleveland Clinic estimates that surgery for CTS has a success rate of over 90
percent, and it is rare for the problem to return.
As with any surgery, there is always a risk of complications, including infection, post-
operative bleeding, nerve injury, and scarring.
Diagnosis
Self-tests for CTS include tapping the wrist lightly to see if this produces a tingling
sensation or numbness in the fingers.
Another test is to flex the wrist or hold it above the head for a minute. If there is pain,
numbness, or tingling, it may mean that CTS is present.
Tinel's test, or Tinel's sign: The doctor taps the median nerve at the wrist lightly to
see whether the patient feels numbness or tingling in one or more fingers.
Phalen's test for wrist-flexion: The patient presses the backs of the hands against
each other so that the wrist is bent. If tingling or numbness occurs within one minute,
there may be damage to the median nerve.
Nerve conduction study: Electrodes are placed on the hand and wrist. Small electric
shocks are applied. The test measures how quickly the nerves transmit the impulses to
the muscles.
Blood tests: Blood tests can detect an underlying condition that can be related to
carpal tunnel syndrome, including hypothyroidism, rheumatoid, arthritis, or diabetes.
Imaging scans: An x-ray can show whether there is a fracture or some other disorder,
such as rheumatoid arthritis. An ultrasound scan can check the structure of the median
nerve. Studies have found that MRI scans are not useful in diagnosing carpal tunnel
syndrome.
Exercises
Here are two exercises that may help relieve the discomfort of CTS:
1. Make a fist, with the back of the hand facing down. Slide the fingers up until they
are pointing straight up toward the ceiling. Repeat five to 10 times.
2. Make a fist. Open your hand and spread out the fingers, stretching them as far as
possible. Repeat five to 10 times.
Causes
The carpal tunnel, also known as the carpal canal, is a narrow, rigid passageway of
bones and ligaments at the base of the hand. The median nerve and tendons are also in
the carpal tunnel.
The carpal tunnel can sometimes narrow because the tendons become irritated and
inflamed, or because some other swelling puts pressure on the median nerve.
Sensations to the palm, the thumb, and three other fingers are controlled by the
median nerve. The median nerve also controls the muscle that brings the thumb across
the palm to touch the little finger. It does not control the little finger.
Pressure on this nerve can lead to pain, numbness, and weakness in the hand and
wrist, and this may cause pain to radiate up the arm and even to the shoulder.
CTS can develop for various reasons. However, it is more likely if the person
frequently uses extremes of wrist motion, if they are exposed to vibration, and if they
repeatedly use their fingers, for example when typing.
repetitive maneuvers
repeated use of vibrating hand tools
work stress
pregnancy, for example, because of edema, or fluid retention
inflammatory, degenerative, and rheumatoid arthritis
hypothyroidism, or an underactive thyroid
diabetes
trauma, such as dislocation or fracture of the wrist
structural problems in the wrist joint
lesions in the wrist
a cyst or tumor in the carpal tunnel
an overactive pituitary gland
any kind of swelling or inflammation around the tendons
Researchers have found that a previous wrist fracture and the use of insulin,
metformin, and sulphonylureas are associated with a higher chance of CTS. Smoking,
hormone replacement therapy (HRT), the combined oral contraceptive pill, and oral
corticosteroids did not appear to be not linked to a higher risk of CTS.
One study has suggested that obesity, combined with a square-shaped wrist shape,
may increase the likelihood of CTS developing. However, the team concluded that
obesity was probably not the cause, because when participants with obesity lost
weight, they continued to have CTS.
The same team concluded in other research that the age of women at the menopause
might be a factor, and that pregnancy-related hormones may increase the risk of CTS
in women at the time of the menopause.
Postmenopausal women who use aromatase inhibitor drugs for breast cancer often
experience CTS.
Apart from work-related factors, the main risk for CTS is inflammatory arthritis, but
hypothyroidism and diabetes also appear to increase the chance of developing it,
according to research published in the Journal of General Internal Medicine.
The National Institute of Neurological Disorders and Stroke (NINDS) says that CTS
is three times more likely to occur among people working in assembly operations than
in data-entry personnel.
The Canadian Centre for Occupational Health and Safety (CCOHS) list the following
occupations as risk factors for CTS:
CTS is linked to repetitive hand movements, but there is no evidence to suggest that
computer use is a significant factor.
Repetitive movements from activities such as knitting can also increase the risk.
Prevention
Measures to reduce the risk of developing CTS include:
Some people recommend hand movement exercises, including yoga, and massages,
but research has not confirmed that these are effective.